RASLE Biospecimen Metadata Template

A template outlining metadata to be collected for biospecimen from the AMP RA/SLE program. Distinct validation rules are in place for this template relative to other biospecimen metadata templates.

Attribute Description Required Valid Values
Component A high-level attribute for grouping attributes into templates. TRUE
individualID Unique identifier assigned to each study participant. For multi-specimen data files provide all IDs in a comma-separated list. TRUE
visitID Ordinal ID distinguishing different patient visits FALSE
biospecimenID A unique identifier assigned to specimens collected from study participants. For multi-specimen data files provide all IDs in a comma-separated list. TRUE
parentBiospecimenID The biospecimenID associated with the originating biospecimen for derived or child biospecimens. FALSE
biospecimenType A label indicating the biological material collected for experimentation and data collection. Where applicable, provide all types in a comma-separated list. TRUE none, urine, stool, whole blood, serum, plasma, PBMCs, total leukocytes, kidney biopsy, synovial fluid, skin biopsy, salivary gland, saliva, skin swab, synovial tissue, suction blister cells, suction blister fluid, uvea
biospecimenSubtype Biospecimen status before sample is processed into a scRNA-seq library. Several scRNA-seq technologies support a variety of sample processing methods which can introduces sources of technical variation. FALSE nuclei suspension, cell suspension, fresh tissue, frozen tissue, FFPE tissue, flow-sorted cells, PFA-fixed tissue