cellType

The cell type name from Cell Ontology for the corresponding CL identifier.

Valid values for this attribute are derived from the Cell Ontology (CL).

Valid Values Description source
neural crest derived fibroblast Any fibroblast that is derived from the neural crest. Synonyms: fibroblast neural crest derived http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
early embryonic cell (metazoa) A cell found in the embryo before the formation of all the gem layers is complete. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
migratory cranial neural crest cell Cell that is part of the migratory cranial neural crest population. Migratory cranial neural crest cells develop from premigratory cranial neural crest cells and have undergone epithelial to mesenchymal transition and delamination. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
migratory trunk neural crest cell Cell that is part of the migratory trunk neural crest population. Migratory trunk neural crest cells develop from premigratory trunk neural crest cells and have undergone epithelial to mesenchymal transition and delamination. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
egg cell A female gamete where meiosis has progressed to metaphase II and is able to participate in fertilization. Synonyms: mature oocyte, ovum http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle cell neural crest derived A smooth muscle cell derived from the neural crest. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
glioblast A non-terminally differentiated cell that develops form the neuroectoderm. Glioblast has the potential to differentiate into various types of glial cells, including astrocytes and oligodendrocytes. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
apocrine cell An exocrine cell characterized by loss of part of the cytoplasm during the process of secretion. The secreted substance is accumulated at the apical end and is either budded off through the plasma membrane producing secreted vesicles or dissolved in the cytoplasm that is lost during secretion. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stem cell A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
single fate stem cell A stem cell that self-renews as well as give rise to a single mature cell type. Synonyms: unipotent stem cell, unipotential stem cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial fate stem cell A somatic stem cell that is committed to an epithelial fate, possessing the capacity for self-renewal and the ability to differentiate into one or more distinct mature cell types of the epithelial lineage. This cell is crucial for the development, homeostasis, repair, and regeneration of epithelial tissues. Synonyms: epithelial stem cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hematopoietic stem cell A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119. Synonyms: blood forming stem cell, hemopoietic stem cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
erythroid progenitor cell A progenitor cell committed to the erythroid lineage. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
monoblast A myeloid progenitor cell committed to the monocyte lineage. This cell is CD11b-positive, has basophilic cytoplasm, euchromatin, and the presence of a nucleolus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature eosinophil A fully differentiated eosinophil, a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Cells are also differentiated from other granulocytes by a small nuclear-to-cytoplasm ratio (1:3). This cell type is CD49d-positive. Synonyms: mature eosinocyte, mature eosinophil leucocyte, mature eosinophil leukocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
neutrophilic myeloblast A myeloblast committed to the neutrophil lineage. This cell type is GATA-1 positive, C/EBPa-positive, AML-1-positive, c-myb-positive and has low expression of PU.1 transcription factor. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature basophil A fully differentiated basophil, a granular leukocyte with an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. Synonyms: mature basophil leucocyte, mature basophil leukocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
multi fate stem cell A stem cell that can give rise to multiple lineages of cells. Synonyms: multi-fate stem cell, multifate stem cell, multipotent cell, multipotent stem cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
common myeloid progenitor A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages. Synonyms: common myeloid precursor http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
megakaryocyte-erythroid progenitor cell A progenitor cell committed to the megakaryocyte and erythroid lineages. Synonyms: CFU-EM, CFU-MegE, MEP, Meg/E progenitor, colony forming unit erythroid megakaryocyte, megakaryocyte/erythrocyte progenitor, megakaryocyte/erythroid progenitor cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
common lymphoid progenitor A oligopotent progenitor cell committed to the lymphoid lineage. Synonyms: common lymphocyte precursor, common lymphocyte progenitor, common lymphoid precursor http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
totipotent stem cell A stem cell from which all cells of the body can form. Synonyms: totipotential stem cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myoblast A cell that is commited to differentiating into a muscle cell. Embryonic myoblasts develop from the mesoderm. They undergo proliferation, migrate to their various sites, and then differentiate into the appropriate form of myocytes. Myoblasts also occur as transient populations of cells in muscles undergoing repair. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
chondroblast Skeletogenic cell that is typically non-terminally differentiated, secretes an avascular, GAG rich matrix; is not buried in cartilage tissue matrix, retains the ability to divide, located adjacent to cartilage tissue (including within the perichondrium), and develops from prechondroblast (and thus prechondrogenic) cell. Synonyms: chrondoplast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ameloblast Skeletogenic cell that produces enamel, overlies the odontogenic papilla, and arises from the differentiation of a preameloblast cell. Synonyms: amelocyte, enamel secreting cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
odontoblast Skeletogenic cell that secretes dentine matrix, is derived from the odontogenic papilla, and develops from a preodontoblast cell. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cementoblast Skeletogenic cell that produces cementum (a bony substance that covers the root of a tooth), is part of the odontogenic papilla, and develops from a precementoblast cell. Synonyms: cementum secreting cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
osteoblast Skeletogenic cell that secretes osteoid, is capable of producing mineralized (hydroxyapatite) matrix, is located adjacent to or within osteoid tissue, and arises from the transformation of a preosteoblast cell. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ciliated cell A cell that has a filiform extrusion of the cell surface. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ependymal cell A neuroepithelial glial cell, derived from a radial glial cell originating from the neuroectoderm, lines the ventricles of the brain and the central canal of the spinal cord. This cell is characterized by the presence of cilia on its apical surface, which can be motile or non-motile. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina. Synonyms: epitheliocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ciliated epithelial cell An epithelial cell that has a cilia. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
duct epithelial cell An epithelial cell that is part of a duct. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
branched duct epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
blood vessel endothelial cell An endothelial cell that lines the vasculature. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
non-branched duct epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
columnar/cuboidal epithelial cell A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
squamous epithelial cell An epithelial cell that has a flattened morphology. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesothelial cell A flat, squamous-like epithelial cell of mesodermal origin. It forms the mesothelium, which lines the body's serous cavities including the pleural, peritoneal, and pericardial spaces. This cell plays a crucial role in synthesizing and secreting lubricants, such as glycosaminoglycans and surfactants, which minimize friction between adjacent tissues during movement. Synonyms: mesotheliocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
peridermal cell Any squamous epithelial cell that is part of some periderm. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stratified epithelial cell An epithelial cell, organized into multiple layers, with only the basal layer being in contact with the basement membrane. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
circulating cell A cell which moves among different tissues of the body, via blood, lymph, or other medium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
blood cell A cell found predominately in the blood. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of lung An epithelial cell of the lung. Synonyms: lung epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of pancreas An epithelial cell of the pancreas. Synonyms: pancreas epithelial cell, pancreatic epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
T cell A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex. Synonyms: T lymphocyte, T-cell, T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Kupffer cell A tissue-resident macrophage of the reticuloendothelial system found on the luminal surface of the hepatic sinusoids involved in erythrocyte clearance. Markers include F4/80+, CD11b-low, CD68-positive, sialoadhesin-positive, CD163/SRCR-positive. Irregular, with long processes including lamellipodia extending into the sinusoid lumen, have flattened nucleus with cytoplasm containing characteristic invaginations of the plasma membrane (vermiform bodies); lie within the sinusoid lumen attached to the endothelial surface; derived from the bone marrow, form a major part of the body's mononuclear phagocyte system. Synonyms: hepatic macrophage, littoral cell of hepatic sinusoid, liver macrophage, macrophagocytus stellatus, stellate cell of von Kupffer, von Kupffer cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
osteoclast A specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes. This cell has the following markers: tartrate-resistant acid phosphatase type 5-positive, PU.1-positive, c-fos-positive, nuclear factor NF-kappa-B p100 subunit-positive, tumor necrosis factor receptor superfamily member 11A-positive and macrophage colony-stimulating factor 1 receptor-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
granulocyte A leukocyte with abundant granules in the cytoplasm. Synonyms: granular leucocyte, granular leukocyte, polymorphonuclear leukocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature neutrophil A fully differentiated neutrophil, a granular leukocyte having a nucleus with three to five lobes connected by slender threads, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes. They are produced in bone marrow at a rate of 5e10-10e10/day and have a half-life of 6-8 hours. Neutrophils are CD15-positive, CD16-positive, CD32-positive, CD43-positive, CD181-positive, and CD182-positive. Synonyms: PMN, mature neutrocyte, mature neutrophil leucocyte, mature neutrophil leukocyte, mature neutrophilic leucocyte, mature neutrophilic leukocyte, polymorphonuclear neutrophil, polynuclear neutrophilic leucocyte, polynuclear neutrophilic leukocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mast cell A cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. Progenitors leave bone marrow and mature in connective and mucosal tissue. Mature mast cells are found in all tissues, except the bloodstream. Their phenotype is CD117-high, CD123-negative, CD193-positive, CD200R3-positive, and FceRI-high. Stem-cell factor (KIT-ligand; SCF) is the main controlling signal of their survival and development. Synonyms: histaminocyte, labrocyte, mastocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
sensory epithelial cell A specialized epithelial cell involved in sensory perception. Restricted to special sense organs of the olfactory, gustatory, and vestibulocochlear receptor systems; contain sensory cells surrounded by supportive, non-receptive cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mononuclear phagocyte A vertebrate phagocyte with a single nucleus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
surface ectodermal cell An ectodermal cell that is part of the external ectoderm, forming the outermost layer of the developing embryo. It is characterized by its polarized nature, with distinct apical and basal surfaces (Ferrante Jr., Reinke, & Stanley, 1995). Surface ectodermal cell gives rise to the epidermis, hair follicles, nails, sensory organs, and specialized structures like the apical ectodermal ridge crucial for limb development (Skoufa et al., 2024). Synonyms: cell of surface ectoderm, surface ectoderm cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endothelial cell An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm. Synonyms: endotheliocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
basket cell Basket cells are inhibitory GABAergic interneurons of the brain. In general, dendrites of basket cells are free branching and contain smooth spines. Axons are highly branched. The branched axonal arborizations give rise to basket-like structures that surround the soma of the target cell. Basket cells form axo-somatic synapses, meaning their synapses target somas of other cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
granule cell A neuron of the vertebrate central nervous system that is small in size. This general class includes small neurons in the granular layer of the cerebellar cortex, cerebral cortex neurons that are not pyramidal cells and small neurons without axons found in the olfactory bulb. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
macroglial cell A neuroglial cell of ectodermal origin, i.e., the astrocytes and oligodendrocytes considered together. Synonyms: macrogliocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
astrocyte A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with 'end feet' which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and 'reactive astrocytes' (along with microglia) respond to injury. Synonyms: astrocytic glia http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
oligodendrocyte A class of large neuroglial (macroglial) cells in the central nervous system. Form the insulating myelin sheath of axons in the central nervous system. Synonyms: OLs http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
microglial cell A transcriptomically distinct central nervous system macrophage found in the parenchyma of the central nervous system. Marker include CD11b-positive, F4/80-positive, and CD68-positive. Synonyms: brain-resident macrophage, hortega cells, microgliocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
gut endothelial cell An endothelial cell that lines the blood and lymphatic vessels of the digestive tract. This cell forms the gut–vascular barrier (GVB) through tight junctions and crosstalk with pericytes and enteric glial cells, regulating the passage of nutrients and immune cells while restricting microbial translocation into the bloodstream. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
corneal endothelial cell An hexagonal, flattened, mitochondria-rich endothelial cell that forms a monolayer on the posterior surface of the cornea (the corneal endothelium). Corneal endothelial cells are derived from the neural crest and are responsible for keeping the cornea transparent by maintaining the tissue in a semi-dry state through the action of their ionic pumps and tight junction barrier. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
neurectodermal cell Ectoderm destined to be nervous tissue. Synonyms: neurectoderm cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesenchymal stem cell A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
circulating fibrocyte A bone marrow-derived cell that predominantly develops from myeloid lineage-restricted progenitor cells and circulates in peripheral blood, characterized by co-expression of hematopoietic markers CD45 and CD34 along with stromal markers including collagen type I in both humans and mice (Chesney et al., 1997; Blakaj and Bucala, 2012). This spindle-shaped cell exhibits a unique dual identity, functionally bridging immune and stromal compartments with characteristics of both monocytes and fibroblasts. Predominantly arising from circulating monocytes, it migrates to injury sites via chemokine receptors and participates in wound repair through extracellular matrix deposition, cytokine secretion, and antigen presentation via MHC class II. As mesenchymal progenitors, fibrocytes can differentiate into fibroblasts, myofibroblasts, and adipocytes, contributing to both physiological repair and pathological fibrosis (Blakaj and Bucala, 2012). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
adipocyte A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides. Synonyms: adipose cell, fat cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
osteocyte A mature osteoblast that has become embedded in the bone matrix. They occupy a small cavity, called lacuna, in the matrix and are connected to adjacent osteocytes via protoplasmic projections called canaliculi. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
chondrocyte A skeletogenic cell that secretes a specialized, avascular, GAG-rich matrix, is embedded in cartilage tissue matrix, retains the ability to divide, and develops from a chondroblast cell. Synonyms: cartilage cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
odontocyte Skeletogenic cell that secretes dentine matrix, is derived from odontogenic papilla. Embedded in dentine tissue, and is the transformation of a non-terminally differentiated odontoblast cell. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cementocyte An osteocytelike cell with numerous processes, trapped in a lacuna in the cement of the tooth. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hyalocyte A cell occurring in the peripheral part of the vitreous body of the eye that may be responsible for production of hyaluronic acid and collagen. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
professional antigen presenting cell A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
simple columnar epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pigment cell A pigment cell is a cell that contains pigment granules. Synonyms: chromatocyte, chromatophore http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
melanocyte A pigment cell derived from the neural crest. Contains melanin-filled pigment granules, which gives a brown to black appearance. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
visual pigment cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
glandular secretory epithelial cell An epithelial cell, located in a gland, that is specialised for the synthesis and secretion of specific biomolecules, such as hormones, or mucous. Synonyms: glandular epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
secretory cell A cell that specializes in controlled release of one or more substances. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
exocrine cell A cell of an exocrine gland; i.e. a gland that discharges its secretion via a duct. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
glycosaminoglycan secreting cell A cell that secretes glycosaminoglycans. Synonyms: GAG secreting cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
protein secreting cell Any secretory cell that is capable of some protein secretion. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
peptic cell An epithelial cell of the stomach that is part of the fundic gastric gland. This cell is characterized by a basally located nucleus, abundant rough endoplasmic reticulum, and large apical secretory granules. It produces and secretes pepsinogen, the inactive precursor of the digestive enzyme pepsin. Synonyms: chief cell of stomach, gastric chief cell, pepsinogen secreting cell, zymogenic cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
surfactant secreting cell A cell that specializes in secretion of surfactant in the alveoli of the lung. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
club cell A non-mucous, epithelial secretory cell that is part of the tracheobronchial tree. A club cell has short microvilli but no cilia. A club cell is able to multiply and differentiate into ciliated cells to regenerate the bronchiolar epithelium and it also protects the tracheobronchial epithelium. Synonyms: Clara cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
seromucus secreting cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
goblet cell A specialized, columnar, mucus secreting epithelial cell shaped like a flask or goblet. A narrow basal end contains the nucleus while the apical end is swollen by the accumulation of mucus laden secretory granules. Short microvilli project from the apical plasma membrane. Synonyms: chalice cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
parietal cell An epithelial cell of the stomach that is part of the fundic gastric gland. This cell is characterized by its pyramidal shape, abundant mitochondria, and a complex network of secretory canaliculi lined with microvilli. It secretes hydrochloric acid into the stomach lumen and produces intrinsic factor, essential for vitamin B12 absorption. Synonyms: gastric parietal cell, oxyntic cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endocrine cell A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions. Synonyms: endocrinocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
enteroendocrine cell An endocrine cell that is located in the epithelium of the gastrointestinal tract or in the pancreas. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
chromaffin cell A cell that stores epinephrine secretory vesicles. During times of stress, the nervous system signals the vesicles to secrete their hormonal content. Their name derives from their ability to stain a brownish color with chromic salts. Characteristically, they are located in the adrenal medulla and paraganglia of the sympathetic nervous system. Synonyms: phaeochromocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
peptide hormone secreting cell Any secretory cell that is capable of some peptide hormone secretion. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
insulin secreting cell Any secretory cell that is capable of some insulin secretion. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type B pancreatic cell A cell that secretes insulin and is located towards the center of the islets of Langerhans. Synonyms: B-cell of pancreatic islet, beta cell of pancreatic islet, insulin-secreting cell, pancreatic B cell, pancreatic B-cell, pancreatic beta cell, pancreatic islet core, type B enteroendocrine cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
glucagon secreting cell A cell that secretes glucagon. Synonyms: glucagon-secreting cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pancreatic A cell A type A enteroendocrine cell found in the periphery of the islets of Langerhans that secretes glucagon. Synonyms: alpha cell of islet of Langerhans, pancreatic alpha cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
somatostatin secreting cell Any secretory cell that is capable of some somatostatin secretion. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pancreatic D cell A D cell located in the pancreas. Peripherally placed within the islets like type A cells; contains somatostatin. Synonyms: D-cell of pancreatic islet, delta cell of islet, delta cell of pancreatic islet, pancreatic D-cell, pancreatic delta cell, somatostatin-secreting pancreatic cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
steroid hormone secreting cell Any secretory cell that is capable of some steroid hormone secretion. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
luteal cell A progesterone secreting cell in the corpus luteum. The large luteal cells develop from the granulosa cells. The small luteal cells develop from the theca cells. Synonyms: corpus luteum cell, lutein cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ecdysteroid secreting cell Any secretory cell that is capable of some ecdysteroid secretion. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
testosterone secreting cell Any secretory cell that is capable of some testosterone secretion. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Leydig cell A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis. Synonyms: interstitial cell of Leydig http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
progesterone secreting cell Any secretory cell that is capable of some progesterone secretion. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
estradiol secreting cell A steroid hormone secreting cell that secretes estradiol. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hepatocyte The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
contractile cell A cell whose primary function is to shorten. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myoepithelial cell Contractile cells resembling smooth muscle cells that are present in glands, notably the mammary gland, and aid in secretion. This cell has long weaving dendritic processes containing myofilament. Synonyms: basket epithelial cell, myoepitheliocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myofibroblast cell An animal cell that has characteristics of both a fibroblast cell and a smooth muscle cell. Synonyms: MFB http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
muscle cell A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. Synonyms: muscle fiber, myocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cell of skeletal muscle A somatic cell located in skeletal muscle. Synonyms: skeletal muscle cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
slow muscle cell A muscle cell that develops tension more slowly than a fast-twitch fiber. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fast muscle cell A muscle cell that can develop high tension rapidly. It is usually innervated by a single alpha neuron. Synonyms: glycolytic muscle fiber http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle cell A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast). Synonyms: SMCs, myocytes, smooth muscle, smooth muscle fiber http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
insect flight muscle cell A muscle cell that is involved in the mechanism of insect flight. This encompasses both, cells that power flight and cells that control flight. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
sensory receptor cell A cell that is capable of detection of a stimulus involved in sensory perception. Synonyms: receptor cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pain receptor cell The peripheral receptor for pain. Includes receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli. All mammalian nociceptors are free nerve endings. Synonyms: nociceptor, nocireceptor http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mechanoreceptor cell A cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
touch receptor cell Any neuron that is capable of some detection of mechanical stimulus involved in sensory perception of touch. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
auditory hair cell A mechanoreceptor cell of the auditory or vestibular system that is sensitive to auditory stimuli. The accessory sensory structures are arranged so that appropriate stimuli cause movement of the hair-like projections (stereocilia and kinocilia) which relay the information centrally in the nervous system. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
gravity sensitive cell Any neuronal receptor cell that is capable of some detection of mechanical stimulus involved in sensory perception. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
acceleration receptive cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
thermoreceptor cell A cellular receptor which mediates the sense of temperature. Thermoreceptor cells in vertebrates are mostly located under the skin. In mammals there are separate types of thermoreceptors for cold and for warmth and pain receptor cells which detect cold or heat extreme enough to cause pain. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
chemoreceptor cell A cell specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptors may monitor external stimuli, as in taste and olfaction, or internal stimuli, such as the concentrations of oxygen and carbon dioxide in the blood. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pH receptor cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
taste receptor cell A specialized cell involved in gustatory sensory perception. Synonyms: taste bud cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
photoreceptor cell A cell specialized in detecting light stimuli that are involved in visual perception. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
electrically active cell A cell whose function is determined by the generation or the reception of an electric signal. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
synovial cell A cell located in the synovial joint. Synonyms: synoviocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myelinating Schwann cell A neuroglial cell of the peripheral nervous system which forms the insulating myelin sheaths of peripheral axons. Synonyms: neurilemmal cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
motile cell A cell that moves by its own activities. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ectodermal cell A cell of the outer of the three germ layers of the embryo. Synonyms: ectoderm cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesodermal cell A cell of the middle germ layer of the embryo. Synonyms: mesoblast, mesoderm cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endodermal cell A cell of the inner of the three germ layers of the embryo. Synonyms: endoderm cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
anucleate cell A cell that lacks a nucleus. Synonyms: non-nucleated cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
single nucleate cell A cell with a single nucleus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
binucleate cell Any cell that has characteristic some binucleate. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
multinucleate cell A cell with more than one nucleus. Synonyms: multinucleated cells, polynuclear cells http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
erythrocyte A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen. Synonyms: RBC, red blood cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
platelet A non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation. Synonyms: anucleate thrombocyte, blood platelet, enucleate thrombocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
phagocyte Any cell capable of ingesting particulate matter via phagocytosis. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
macrophage A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells. Synonyms: histiocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
B cell A lymphocyte of B lineage that is capable of B cell mediated immunity. Synonyms: B lymphocyte, B-cell, B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
keratinizing barrier epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
non keratinizing barrier epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
brush border epithelial cell An epithelial cell characterized by the presence of a brush border on its apical surface, which increases the surface area for absorption. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stratified squamous epithelial cell A stratified epithelial cell that is part of squamous epithelium, characterized by multiple layers of cells. The basal layer is directly attached to the basement membrane and the apical layer consists of flattened squamous cells. This provides a protective barrier, commonly found in areas subject to abrasion, such as the skin, oral cavity, and esophagus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stratified cuboidal epithelial cell A stratified epithelial cell that is part of cuboidal epithelium, characterized by multiple layers of cuboidal cells forming the apical layer. This provides a protective lining for ducts in large glands, such as sweat glands. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Merkel cell A specialized epithelial cell located in the skin epidermis and certain mucosal epithelia. It functions as a mechanoreceptor for light touch by forming synapse-like contacts with somatosensory afferent nerve endings, contributing to slowly adapting type I (SAI) tactile responses. Characterized by dense-core neuroendocrine granules, the Merkel cell exhibits both sensory and neuroendocrine properties, including regulated neurotransmitter release via SNARE complex-dependent mechanisms. Its development in mice depends on the transcription factor Atoh1. Synonyms: Merkel's cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
transitional epithelial cell A cell characteristically found lining hollow organs that are subject to great mechanical change due to contraction and distention; originally thought to represent a transition between stratified squamous and columnar epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hatching gland cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
extramedullary cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
eurydendroid cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
eukaryotic cell Any cell that in taxon some Eukaryota. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
uric acid accumulating cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
eye photoreceptor cell Any photoreceptor cell that is part of some eye. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
somatotropin secreting cell A peptide hormone secreting cell that produces growth hormone, somatotropin. Synonyms: growth hormone secreting cell, somatotrophin secreting cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
gamete A mature sexual reproductive cell having a single set of unpaired chromosomes. Synonyms: haploid nucleated cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
crystallin accumulating cell Synonyms: lens cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tracheal epithelial cell An epithelial cell found in the trachea. Synonyms: tracheocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
metal ion accumulating cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
copper accumulating cell Synonyms: cuprophilic cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
iron accumulating cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
keratin accumulating cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
keratinocyte An epithelial cell of stratified squamous tissues, including skin, oral mucosa (Hiroshima et al., 2011), and esophagus (Whelan et al., 2018), that produces keratin proteins and secretes antimicrobial peptides to form a resilient barrier against environmental damage, dehydration, pathogens, and microbial invasion. It undergoes successive stages of differentiation marked by changes in keratin expression, supporting tissue integrity, wound repair, and contributing to immune defense. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
serous secreting cell Columnar glandular cell with irregular nucleus, copious granular endoplasmic reticulum and supranuclear granules. Secretes a watery fluid containing proteins known as serous fluid. Synonyms: serous cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
milk secreting cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tear secreting cell A cell secreting tears, the fluid secreted by the lacrimal glands. This fluid moistens the conjunctiva and cornea. Synonyms: tears secreting cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
sebocyte An epithelial cell that is part of a sebaceous gland. This cell produces and secretes sebum, an oily, lipid-rich substance, through holocrine secretion where the entire cell ruptures to release its contents. Synonyms: sebum secreting cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
sweat secreting cell A cell secreting sweat, the fluid excreted by the sweat glands of mammals. It consists of water containing sodium chloride, phosphate, urea, ammonia, and other waste products. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mucus secreting cell Any cell that is capable of some mucus secretion. Synonyms: mucous cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pulmonary alveolar epithelial cell An epithelial cell that lines the peripheral gas exchange region of the lungs of air-breathing vertebrates. Synonyms: alveolar epithelial cell, alveolus of lung epithelial cell, epithelial cell of alveolus of lung, pneumocyte, pneumonocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lysozyme secreting cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
metanephric mesenchyme stem cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stuff accumulating cell A cell that is specialised to accumulate a particular substance(s). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
glycogen accumulating cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
extracellular matrix secreting cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
oxygen accumulating cell Any cell that is capable of some oxygen transport. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
migratory neural crest cell A cell derived from the specialized ectoderm flanking each side of the embryonic neural plate, which after the closure of the neural tube, forms masses of cells that migrate out from the dorsal aspect of the neural tube to spread throughout the body. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesenchyme condensation cell A mesenchymal cell in embryonic development found in a contracting mass and that gives rise to osteoprogenitors. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
adrenal medulla chromaffin cell A cell found within the adrenal medulla that secrete biogenic amine hormones upon stimulation. Synonyms: medullary chromaffin cell of adrenal gland http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
dental papilla cell A mesenchymal cell that is part of a small mass of condensed mesenchyme in the enamel organ; it differentiates into the dentin and dental pulp. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hair follicle dermal papilla cell A specialized fibroblast that resides in the dermal papilla located at the bottom of hair follicles. This cell orchestrates reciprocal epithelial-mesenchymal signaling essential for hair follicle morphogenesis and cycling, regulating matrix cell proliferation and differentiation to control hair shaft size, shape, and growth. The dermal papilla cell is replenished each hair cycle from bipotent hair follicle dermal stem cells in the dermal sheath that simultaneously self-renew and contribute progeny to the papilla, particularly during anagen. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
scleral cell A cell of the sclera of the eye. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
choroidal cell of the eye A cell that is part of optic choroid. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
extraembryonic cell Any cell that is part of some extraembryonic structure. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
trophoblast cell An extraembryonic cell that develops from a trophectodermal cell. This cell is found in the outer layer of the blastocyst and can invade other structures in the uterus once the blastocyst implants into the uterine wall. A trophoblast cell is involved in the implantation of the embryo into the uterine wall, placental formation, remodelling of maternal vasculature in the uterus, nutrient and gas exchange, hormone production, and immune modulation to support fetal development. Synonyms: trophoblastic cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epiblast cell A cell of the outer layer of a blastula that gives rise to the ectoderm after gastrulation. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
blastoderm cell An undifferentiated cell produced by early cleavages of the fertilized egg (zygote). Synonyms: blastomere http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
blastemal cell Synonyms: blastema cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
multi-potent skeletal muscle stem cell A multifate stem cell found in skeletal muscle than can differentiate into many different cell types, including muscle. Distinct cell type from satellite cell. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hair matrix stem cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stratified epithelial stem cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
sphincter associated smooth muscle cell A smooth muscle cell that is part of a sphincter. A sphincter is a typically circular muscle that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
vascular associated smooth muscle cell A smooth muscle cell associated with the vasculature. Synonyms: VSMC, vascular smooth muscle cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
morula cell A cell of the early embryo at the developmental stage in which the blastomeres, resulting from repeated mitotic divisions of the fertilized ovum (zygote), form a compact cell mass. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
gastrula cell A cell of the embryo in the early stage following the blastula, characterized by morphogenetic cell movements, cell differentiation, and the formation of the three germ layers. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epidermal cell An epithelial cell of the integument (the outer layer of an organism). Synonyms: cell of epidermis http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
animal zygote Diploid cell produced by the fusion of sperm cell nucleus and egg cell. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
humidity receptor cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tracheoblast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
thecogen cell The support cell that makes the thecogen dendritic cap - a cuticle-like matrix around the tip of the eo-dendrite and which encloses the soma of the eo-neuron. Synonyms: fly sheath cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
nephrogenic mesenchyme stem cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ligament cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tendon cell An elongated fibroblast that is part of a tendon. Its cytoplasm is stretched between the collagen fibres of the tendon, and it possesses a central nucleus with a prominent nucleolus. Tendon cell has a well-developed rough endoplasmic reticulum, and it is responsible for the synthesis and turnover of tendon fibres and ground substance. Synonyms: muscle attachment cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
electrically responsive cell A cell whose function is determined by its response to an electric signal. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
electrically signaling cell A cell that initiates an electrical signal and passes that signal to another cell. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
polyploid cell A cell that contains more than two haploid sets of chromosomes. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
haploid cell A cell whose nucleus contains a single haploid genome. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
diploid cell A cell whose nucleus has two haploid genomes. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
polytene cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endopolyploid cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
seam cell An epithelial fate stem cell found in flatworms. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
syncytial epithelial cell An epithelial cell that forms a syncytium, which is a multinucleated cell resulting from the fusion of multiple cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mitogenic signaling cell A cell whose primary function is to cause growth by stimulating cell division in its immediate cellular environment. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tip cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
excretory cell A cell involved in the elimination of metabolic and foreign toxins, and in maintaining the ionic, acid-base and water balance of biological fluids. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pore cell Forms the terminal part of the cuticle-lined excretory duct of C. elegans. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
GLR cell A scaffolding cell type found in C. elegans, this cell plays a supportive role to the muscle arms. May also have an endocrine role. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
yolk cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
xanthophore cell A pigment cell derived from the neural crest. Contains cartenoid pigments in structures called pterinosomes or xanthosomes. This gives an appearance ranging from a golden yellow to orange and red. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
iridophore A pigment cell derived from the neural crest. The cell contains flat light-reflecting platelets, probably of guanine, in stacks called reflecting platelets or iridisomes. The color-generating components produce a silver, gold, or iridescent color. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
reticular cell A fibroblast that synthesizes collagen and uses it to produce reticular fibers, thus providing structural support. Reticular cells are found in many organs, including the spleen, lymph nodes and kidneys. Subtypes of reticular cells include epithelial, mesenchymal, and fibroblastic reticular cells. Fibroblastic reticular cells are involved in directing B cells and T cells to specific regions within a tissue, whereas epithelial and mesenchymal reticular cells are associated with certain areas of the brain. Synonyms: reticulum cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
eccrine cell A secretory cell that discharges its product without loss of cytoplasm. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
alkali secreting cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
vaginal lubricant secreting cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
gonadtroph A rounded cell that is usually situated next to sinusoids; secretes follicular stimulating hormone (FSH) and luteinizing hormone (LH). Synonyms: delta basophil, follicle stimulating hormone secreting cell, gonadotrope, gonadotrope cell, gonadotroph, gonadotropic cell, pituitary delta cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
luteinizing hormone secreting cell A peptide hormone secreting cell pituitary that produces luteinizing hormone. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
prolactin secreting cell A peptide hormone cell that secretes prolactin. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
melanocyte stimulating hormone secreting cell A cell of the intermediate pituitary that produces melanocyte stimulating hormone. Synonyms: melanotrope, melanotroph http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
follicular dendritic cell A cell with extensive dendritic processes found in the B cell areas (primary follicles and germinal centers) of lymphoid tissue. They are unrelated to the dendritic cell associated with T cells. Follicular dendritic cells have Fc receptors and C3b receptors, but unlike other dendritic cells, they do not process or present antigen in a way that allows recognition by T cells. Instead, they hold antigen in the form of immune complexes on their surfaces for long periods and can present antigen to B cells during an immune response. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
calcitonin secreting cell Any secretory cell that is capable of some calcitonin secretion. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
obliquely striated muscle cell A muscle cell in which the fibers are organised into sarcomeres but in which adjacent myofibrils are offset from each other, producing an oblique banding pattern. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
apoptosis fated cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
chief cell of parathyroid gland An epithelial cell of the parathyroid gland that is arranged in wide, irregular interconnecting columns; responsible for the synthesis and secretion of parathyroid hormone. Synonyms: parathyroid chief cell, parathyroid gland chief cell, parathyroid hormone secreting cell, principal cell of parathyroid gland http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
carbohydrate secreting cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
white adipocyte An adipocyte with light coloration and few mitochondria. It contains a scant ring of cytoplasm surrounding a single large lipid droplet or vacuole. Synonyms: white adipose cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
brown adipocyte A cell from the thermogenic form of adipose tissue found in many species, particularly in newborns and hibernating mammals, but also in lesser amounts in adults of other mammals including humans. Brown fat is capable of rapid liberation of energy and seems to be important in the maintenance of body temperature immediately after birth and upon waking from hibernation. Synonyms: brown adipose cell, brown fat cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
dendritic cell A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Langerhans cell Langerhans cell is a conventional dendritic cell that has plasma membrane part CD207. A Langerhans cell is a stellate dendritic cell of myeloid origin, that appears clear on light microscopy and has a dark-staining, indented nucleus and characteristic inclusions (Birbeck granules) in the cytoplasm; Langerhans cells are found principally in the stratum spinosum of the epidermis, but they also occur in other stratified epithelia and have been identified in the lung, lymph nodes, spleen, and thymus. Synonyms: LC http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epinephrine secreting cell A cell capable of producing epinephrine. Epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme, which is expressed in the adrenal glands, androgenic neurons, and in other cell types. Synonyms: adrenaline secreting cell, epinephrin secreting cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mineralocorticoid secreting cell Any secretory cell that is capable of some mineralocorticoid secretion. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
biogenic amine secreting cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
serotonin secreting cell A cell type that secretes 5-Hydroxytryptamine (serotonin). Synonyms: 5-HT secreting cell, 5-Hydroxytryptamine secreting cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
noradrenergic cell A cell capable of producting norepiniphrine. Norepiniphrine is a catecholamine with multiple roles including as a hormone and a neurotransmitter. In addition, epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme. Synonyms: noradrenaline secreting cell, norepinephrin secreting cell, norepinephrine secreting cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
glucocorticoid secreting cell Any secretory cell that is capable of some glucocorticoid secretion. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epidermoblast An epidermal progenitor cell that arises from neuroectoderm and in turn gives rise to the epidermal sheath of ventral and cephalic regions. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
adrenocorticotropic hormone secreting cell A peptide hormone secreting cell that produces adrenocorticotropin, or corticotropin. Synonyms: ACTH secreting cell, adrenocorticotrophic hormone secreting cell, corticotrophin hormone secreting cell, corticotropin hormone secreting cell, corticotropin secreting cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
digestive enzyme secreting cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
thyrotroph A basophil cell of the anterior pituitary that produces thyroid stimulating hormone, thyrotrophin. This cell type is elongated, polygonal and lie in clusters towards the adenohypophyseal center. Synonyms: beta-basophil, thyroid stimulating hormone secreting cell, thyrotrope http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
oxytocin stimulating hormone secreting cell A peptide hormone secreting cell that secretes oxytocin stimulating hormone http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
vasopressin stimulating hormone secreting cell A peptide hormone secreting cell that secretes vasopressin stimulating hormone http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
secretin stimulating hormone secreting cell A peptide hormone secreting cell that secretes secretin stimulating hormone http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cholecystokin stimulating hormone secreting cell A peptide hormone secreting cell that secretes cholecystokin stimulating hormone. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
juvenile hormone secreting cell An endocrine cell that secretes juvenile hormone. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
bombesin stimulating hormone secreting cell A peptide hormone secreting cell that secretes bombesin stimulating hormone. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
connective tissue type mast cell Mast cell subtype whose granules contain both the serine proteases tryptase and chymase. These cells are primarily found in connective tissue, such as the peritoneal cavity, skin, and intestinal submucosa. Their development is T-cell independent. Synonyms: MC(TC), MCTC, TC mast cells http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mucosal type mast cell Mast cell subtype that contains only the serine protease trypase in its granules. These cells are primarily found in mucosal tissue, such as intestinal mucosa and alveoli. They depend upon T-cells for development of phenotype. Synonyms: MC(T), MCT, T mast cells http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
visible light photoreceptor cell A photoreceptor cell that detects visible light. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
scotopic photoreceptor cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
photopic photoreceptor cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD4-positive helper T cell A CD4-positive, alpha-beta T cell that cooperates with other lymphocytes via direct contact or cytokine release to initiate a variety of immune functions. Synonyms: CD4-positive T-helper cell, CD4-positive helper T lymphocyte, CD4-positive helper T-cell, CD4-positive helper T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
UV sensitive photoreceptor cell A photoreceptor cell that detects ultraviolet light. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
blue sensitive photoreceptor cell A photoreceptor cell that is sensitive to blue light. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
green sensitive photoreceptor cell A photoreceptor cell that is sensitive to green light. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
red sensitive photoreceptor cell A photoreceptor cell that is sensitive to red light. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stromal cell A connective tissue cell of an organ found in the loose connective tissue. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
follicular epithelial cell An epithelial somatic cell associated with a maturing oocyte. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
granulosa cell A supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge. Granulosa cells form a single layer around the mammalian oocyte in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the ovum in the Graafian follicle. The major functions of granulosa cells include the production of steroids and LH receptors. Synonyms: granulosa cell of ovary http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type D enteroendocrine cell A cell found throughout the gastrointestinal tract and in the pancreas. They secrete somatostatin in both an endocrine and paracrine manner. Somatostatin inhibits gastrin, cholecystokinin, insulin, glucagon, pancreatic enzymes, and gastric hydrochloric acid. A variety of substances which inhibit gastric acid secretion (vasoactive intestinal peptide, calcitonin gene-related peptide, cholecystokinin, beta-adrenergic agonists, and gastric inhibitory peptide) are thought to act by releasing somatostatin. Synonyms: D cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
theca cell A specialized stromal cell that forms the theca layer outside the basal lamina lining the ovarian follicle, appearing during the secondary follicle stage. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
enterochromaffin-like cell A enteroendocrine cell part of the glands of the gastric mucosa. They produce histamine and peptides such as chromogranins. This cell type respond to gastrin by releasing histamine which acts as a paracrine stimulator of the release of hydrochloric acid from the gastric parietal cells. Synonyms: ECL http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
substance P secreting cell A peptide hormone secreting cell that secretes substance P. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
enkephalin secreting cell An endorphine cell that secretes enkephalin. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endorphin secreting cell A peptide hormone secreting cell that secretes endorphin. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type G enteroendocrine cell An endocrine cell found in the stomach and duodenum and is responsible for the secretion of gastrin and enkephalin. Most abundant in pyloric antrum, pyramidal in form with a narrow apex bearing long microvilli. Synonyms: G cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
gastrin secreting cell A peptide hormone secreting cell that secretes gastrin. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
paneth cell An epithelial cell found in the basal part of the intestinal glands (crypts of Lieberkuhn) including the appendix. Paneth cells synthesize and secrete lysozyme and cryptdins. Numerous in the deeper parts of the intestinal crypts, particularly in the duodenum, rich in zinc, contain large acidophilic granules, with irregular apical microvilli and prominent membrane-bound vacuoles containing matrix. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
androgen binding protein secreting cell A peptide hormone secreting cell that secretes androgen binding protein. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cardiac muscle myoblast A precursor cell destined to differentiate into cardiac muscle cell. Synonyms: cardiac muscle progenitor cell, cardiomyocyte progenitor cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle myoblast A precursor cell destined to differentiate into smooth muscle myocytes. Synonyms: myoblast, smooth muscle http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
skeletal muscle myoblast A myoblast that differentiates into skeletal muscle fibers. Synonyms: skeletal myoblast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
macrophage derived foam cell A type of foam cell derived from a macrophage containing lipids in small vacuoles and typically seen in atherolosclerotic lesions, as well as other conditions. Synonyms: lipophage http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mononuclear cytotrophoblast cell A cell from the inner layer of the trophoblast of the early mammalian embryo that gives rise to the outer surface and villi of the chorion. Mononuclear crytoblasts fuse to give rise to a multinuclear cytotrophoblast. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
syncytiotrophoblast cell A cell from the outer syncytial layer of the trophoblast of an early mammalian embryo, directly associated with the maternal blood supply. It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy. Synonyms: syncytial trophoblast cell, syncytiotrophoblastic cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pigmented epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
melanoblast A cell that originates from the neural crest and differentiates into a pigment cell. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lymphocyte A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
slowly adapting mechanoreceptor cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
T-helper 1 cell A CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive, CXCR3-positive, CCR6-negative, and is capable of producing interferon-gamma. Synonyms: T helper cells type 1, T(H)-1 cell, Th1 CD4+ T cell, Th1 T cell, Th1 T lymphocyte, Th1 T-cell, Th1 T-lymphocyte, Th1 cell, helper T cell type 1 http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
T-helper 2 cell A CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive, CXCR3-negative, CCR6-negative, and is capable of producing interleukin-4. Synonyms: T helper cells type 2, T(H)-2 cell, Th2 T cell, Th2 T lymphocyte, Th2 T-cell, Th2 T-lymphocyte, Th2 cell, helper T cell type 2 http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
proerythroblast An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers. Synonyms: rubriblast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
basophilic erythroblast A nucleated immature erythrocyte, having cytoplasm generally similar to that of the earlier proerythroblast but sometimes even more basophilic, and usually regular in outline. The nucleus is still relatively large, but the chromatin strands are thicker and more deeply staining, giving a coarser appearance; the nucleoli have disappeared. This cell is CD71-positive and lacks hematopoeitic lineage markers. Synonyms: basophilic normoblast, early erythroblast, early normoblast, prorubricyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
polychromatophilic erythroblast A nucleated, immature erythrocyte in which the nucleus occupies a relatively smaller part of the cell than in its precursor, the basophilic erythroblast. The cytoplasm is beginning to acquire hemoglobin and thus is no longer a purely basophilic, but takes on acidophilic aspects, which becomes progressively more marked as the cell matures. The chromatin of the nucleus is arranged in coarse, deeply staining clumps. This cell is CD71-positive and lacks hematopoeitic lineage markers. Synonyms: intermediate erythroblast, intermediate normoblast, polychromatic erythroblast, polychromatic normoblast, polychromatophilic normoblast, rubricyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
unimodal nocireceptor http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
orthochromatic erythroblast The final stage of the nucleated, immature erythrocyte, before nuclear loss. Typically the cytoplasm is described as acidophilic, but it still shows a faint polychromatic tint. The nucleus is small and initially may still have coarse, clumped chromatin, as in its precursor, the polychromatophilic erythroblast, but ultimately it becomes pyknotic, and appears as a deeply staining, blue-black, homogeneous structureless mass. The nucleus is often eccentric and sometimes lobulated. Synonyms: acidophilic erythroblast, eosinophilic erythroblast, late erythoblast, orthochromatic normoblast, pyknotic eto enrythroblast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
megakaryocyte progenitor cell The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative). Synonyms: CFU-Meg, Meg-CFC, MkP, colony-forming unit-megakaryocyte, megacaryoblast, megacaryocyte progenitor cell, megakaryoblast, megakaryocytic progenitor cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
gastrin stimulating hormone secreting cell A peptide hormone secreting cell that secretes gastrin stimulating hormone. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
megakaryocyte A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release. Synonyms: megacaryocyte, megalocaryocyte, megalokaryocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
granulocyte monocyte progenitor cell A hematopoietic progenitor cell that is committed to the granulocyte and monocyte lineages. These cells are CD123-positive, and do not express Gata1 or Gata2 but do express C/EBPa, and Pu.1. Synonyms: colony forming unit granulocyte macrophage, granulocyte-macrophage progenitor, granulocyte/monocyte precursor, granulocyte/monocyte progenitor http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
reticulocyte An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
promonocyte A precursor in the monocytic series, being a cell intermediate in development between the monoblast and monocyte. This cell is CD11b-positive and has fine azurophil granules. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
band form neutrophil A late neutrophilic metamyelocyte in which the nucleus is indented to more than half the distance to the farthest nuclear margin but in no area being condensed to a single filament. The nucleus is in the form of a curved or coiled band, not having acquired the typical multilobar shape of the mature neutrophil. These cells are fMLP receptor-positive, CD11b-positive, CD35-negative, and CD49d-negative. Synonyms: rod neutrophil http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
nucleate erythrocyte An erythrocyte having a nucleus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
neutrophilic promyelocyte A promyelocyte committed to the neutrophil lineage. This cell type is GATA-1-positive, C/EBPa-positive, AML-1-positive, MPO-positive, has low expression of PU.1 transcription factor and lacks lactotransferrin expression. Synonyms: neutrophilic premyelocyte, neutrophilic progranulocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fat body cell A cell found in fat bodies whose primary function is intermediary metabolism. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
angioblastic mesenchymal cell A mesenchymal stem cell capable of developing into blood vessel endothelium. Synonyms: angioblast, chondroplast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
polymodal nocireceptor http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
amine precursor uptake and decarboxylation cell A cell that originates in the neural crest, that has certain cytochemical and ultrastructural characteristics and is found scattered throughout the body; types include melanocytes, the cells of the chromaffin system, and cells in the hypothalamus, hypophysis, thyroid, parathyroids, lungs, gastrointestinal tract, and pancreas. This cell type concentrates the amino acid precursors of certain amines and decarboxylate them, forming amines that function as regulators and neurotransmitters. This cell type produces substances such as epinephrine, norepinephrine, dopamine, serotonin, enkephalin, somatostatin, neurotensin, and substance P, the actions of which may affect contiguous cells, nearby groups of cells, or distant cells, thus functioning as local or systemic hormones. The name is an acronym for amine precursor uptake and decarboxylation cell. Synonyms: APUD cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cardiac mesenchymal cell A mesenchymal cell found in the developing heart and that develops into some part of the heart. These cells derive from intra- and extra-cardiac sources, including the endocardium, epicardium, neural crest, and second heart field. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
parafollicular cell A neuroepithelial cells that occurs singly or in small groups, close to the outer follicular borders but within the follicular basement membrane of the thyroid. This cell expresses a form of the neural cell adhesion molecule (N-CAM) on its surface and secretes calcitonin and serotonin (5-hydroxytryptamine). Synonyms: C cell, C cell of thyroid gland, clear cell of thyroid gland, parafollicular cell of thyroid gland, thyroid parafollicular cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
leucophore A pigment cell derived from the neural crest. Contains uric acid or other purine crystals deposited in stacks called leucosomes. The crystals reflect light and this gives a white appearance under white light. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
retinal cone cell One of the two photoreceptor cell types in the vertebrate retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
erythrophore A pigment cell derived from the neural crest. Contains pteridine and/or carotenoid pigments in structures called pterinosomes or erythrosomes. This gives an orange to red appearance. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
corneal epithelial cell An epithelial cell of the cornea. Synonyms: epithelial cell of cornea http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
monocyte Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type EC enteroendocrine cell A subtype of enteroendocrine cells found in the gastrointestinal mucosa, particularly in the glands of pyloric antrum; duodenum; and ileum. These cell type secretes serotonin and some neurotransmitters including enkephalins and substance P. Their secretory granules stain readily with silver (argentaffin stain). Synonyms: Kulchitsky cell, argentaffin cell, enterochromaffin cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
experimentally modified cell in vitro A cell in vitro that has undergone physical changes as a consequence of a deliberate and specific experimental procedure. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
neutrophilic myelocyte A neutrophil precursor in the granulocytic series, being a cell intermediate in development between a promyelocyte and a metamyelocyte; in this stage, production of primary granules is complete and neutrophil-specific granules has started. No nucleolus is present. This cell type is CD13-positive, CD16-negative, integrin alpha-M-positive, CD15-positive, CD33-positive, CD24-positive, C/EBP-a-positive, C/EBPe-positive, PU.1-positive, lactotransferrin-positive, myeloperoxidase-positive and NGAL-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
peritoneal macrophage A macrophage resident in the peritoneum under non-inflammatory conditions. Markers include F4/80-high, CD11b-high, CD68-positive, SIGNR1-positive, CD115-high, MHC-II-negative, and Dectin-1-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
neutrophilic metamyelocyte A neutrophil precursor in the granulocytic series, being a cell intermediate in development between a myelocyte and the band form neutrophil. The protein synthesis seen in earlier stages decreases or stops; the nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare; and the cytoplasm becomes amphophilic like that of a mature granulocyte. This cell type is integrin alpha-M-positive, CD13-negative, CD15-positive, CD16-positive, CD33-positive, CD24-positive, fMLP receptor-negative and has expression of C/EBP-a, C/EBP-e, PU.1 transcription factor, lactotransferrin, myeloperoxidase and neutrophil gelatinase associated lipocalin. Synonyms: juvenile neutrophil http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
alveolar macrophage A tissue-resident macrophage found in the alveoli of the lungs. Ingests small inhaled particles resulting in degradation and presentation of the antigen to immunocompetent cells. Markers include F4/80-positive, CD11b-/low, CD11c-positive, CD68-positive, sialoadhesin-positive, dectin-1-positive, MR-positive, CX3CR1-negative. Synonyms: dust cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
enterocyte An epithelial cell that has its apical plasma membrane folded into microvilli to provide ample surface for the absorption of nutrients from the intestinal lumen. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cold sensing thermoreceptor cell A thermoreceptor cell that detects reduced temperatures. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
odontoclast A specialized osteoclast associated with the absorption and removal of cementum. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cochlear inner hair cell A bulbous cell that is medially placed in one row in the organ of Corti. In contrast to the outer hair cells, the inner hair cells are fewer in number, have fewer sensory hairs, and are less differentiated. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
small luteal cell A progesterone secreting cell in the corpus luteum that develops from theca cells. Synonyms: small lutein cell, theca lutein cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
warmth sensing thermoreceptor cell A thermoreceptor cell that detects increased temperatures. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
large luteal cell A large, progesterone secreting cell in the corpus luteum that develops from the granulosa cells. Synonyms: granulosa lutein cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
androgen secreting cell A steroid hormone secreting cell that secretes androgen. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
skeletal muscle satellite cell An elongated, spindle-shaped, cell that is located between the basal lamina and the plasmalemma of a muscle fiber. These cells are mostly quiescent, but upon activation they divide to produce cells that generate new muscle fibers. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
enucleate erythrocyte An erythrocyte lacking a nucleus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cochlear outer hair cell A mechanoreceptor in the organ of Corti. In mammals the outer hair cells are arranged in three rows which are further from the modiolus than the single row of inner hair cells. The motile properties of the outer hair cells may contribute actively to tuning the sensitivity and frequency selectivity of the cochlea. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pressoreceptor cell A receptor in the vascular system, particularly the aorta and carotid sinus, which is sensitive to stretch of the vessel walls. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
retinal rod cell One of the two photoreceptor cell types of the vertebrate retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
vestibular hair cell A mechanoreceptor located in the acoustic maculae and the semicircular canals that mediates the sense of balance, movement, and head position. The vestibular hair cells are connected to accessory structures in such a way that movements of the head displace their stereocilia. This influences the membrane potential of the cells which relay information about movements via the vestibular part of the vestibulocochlear nerve to the brain stem. Synonyms: vestibular receptor cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
eosinophil progenitor cell Any granulocytopoietic cell that has part some transcription factor PU.1 and has part some CCAAT/enhancer-binding protein alpha and has part some erythroid transcription factor and lacks plasma membrane part some CD19 molecule and lacks plasma membrane part some CD4 molecule and lacks plasma membrane part some integrin alpha-M and lacks plasma membrane part some CD3 epsilon and lacks plasma membrane part some neural cell adhesion molecule 1 and lacks plasma membrane part some CD2 molecule and lacks plasma membrane part some T-cell surface glycoprotein CD8 alpha chain and lacks plasma membrane part some membrane-spanning 4-domains subfamily A member 1 and lacks plasma membrane part some T-cell surface glycoprotein CD5 and lacks plasma membrane part some CD14 molecule and lacks plasma membrane part some lymphocyte antigen 6G and lacks plasma membrane part some lymphocyte antigen 76 (mouse) and has plasma membrane part some CD34 molecule and has plasma membrane part some ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 and has plasma membrane part some interleukin-3 receptor class 2 alpha chain and has plasma membrane part some interleukin-5 receptor subunit alpha and has plasma membrane part some mast/stem cell growth factor receptor and is capable of some eosinophil differentiation. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
eosinophilic myelocyte A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a promyelocyte and a metamyelocyte;in this stage, production of primary granules is complete and eosinophil-specific granules has started. No nucleolus is present. These cells are integrin alpha-M-positive, CD13-positive, CD15-positive, CD16-negative, CD24-positive, and CD33-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
basophil progenitor cell A progenitor cell committed to the basophil lineage. This cell lacks hematopoietic lineage markers (lin-negative) and is CD34-positive, T1/ST2-low, CD117-negative, and FceRIa-high. This cell also expresses Gata-1, Gata-2 and C/EBPa. Synonyms: BaP http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
basophilic myelocyte A basophil precursor in the granulocytic series, being a cell intermediate in development between a promyelocyte and a metamyelocyte; in this stage, production of primary granules is complete and basophil-specific granules has started. No nucleolus is present. Markers are being integrin alpha-M-positive, fucosyltransferase FUT4-positive, CD33-positive, CD24-positive, aminopeptidase N-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
sheath cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fusion competent myoblast A myoblast that is committed to a myotube-specific program of differentiation but not yet fused. It undergoes very limited additional proliferation. After fusion, it will take on a muscle identity specified by a `muscle founder cell` (CL:0008006). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
acinar cell A secretory cell that is grouped together with other cells of the same type to form grape shaped clusters known as acini (singular acinus). Synonyms: acinic cell, acinous cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
natural killer cell A lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors and also regulate immune responses via cytokine release and direct contact with other cells. Synonyms: NK cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD4-positive, alpha-beta T cell A mature alpha-beta T cell that expresses an alpha-beta T cell receptor and the CD4 coreceptor. Synonyms: CD4-positive, alpha-beta T lymphocyte, CD4-positive, alpha-beta T-cell, CD4-positive, alpha-beta T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD8-positive, alpha-beta T cell A T cell expressing an alpha-beta T cell receptor and the CD8 coreceptor. Synonyms: CD8-positive, alpha-beta T lymphocyte, CD8-positive, alpha-beta T-cell, CD8-positive, alpha-beta T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
olfactory granule cell A granule cell that has a soma located in an olfactory bulb granule cell layer. An olfactory granule cell is an interneuron that lacks an axon, makes reciprocal dendro-dendritic synapses with mitral cells and tufted cells and is involved in the fine spatio-temporal tuning of the responses of these principal olfactory bulb neurons to odors. Synonyms: olfactory bulb granule cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
storage cell A cell that is specialized to store a particular substance(s), which is(are) later released from the store for a particular purpose. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
supporting cell A cell whose primary function is to support other cell types. Synonyms: supportive cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
labyrinth supporting cell Cells forming a framework supporting the organ of Corti. Specific cells are those of Claudius, Deiters and Hensen. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hepatic stellate cell A cell that is found in the perisinusoidal space of the liver that is capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components that can contribute to liver fibrosis. This activated state has a myofibroblast-like phenotype, though it's not clear in the literature if this is terminally differentiated. This cell type comprises approximately 8-15% of total cells in the liver. Synonyms: Ito cell, hepatic perisinusoidal cell, perisinusoidal cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Hensen cell A tall supporting cell that is arranged in rows adjacent to the last row of outer phalangeal cells. This cell type constitutes the outer border of the organ of Corti. Synonyms: Hensen's cell, cell of Hensen, external limiting cell of organ of Corti http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Claudius cell A cuboidal cell which along with Boettcher's cells form the floor of the external spiral sulcus, external to the organ of Corti. Synonyms: cell of Claudius http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Deiter's cell The outer phalangeal cells of the organ of Corti. This cell holds the base of the hair cell in a cup-shaped depression. Synonyms: Deiters cell, outer phalangeal cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Mueller cell Astrocyte-like radial glial cell that extends vertically throughout the retina, with the nucleus are usually in the middle of the inner nuclear layer. Synonyms: Muller cell, Muller glia, Müller cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
chromophil cell of anterior pituitary gland A cell that stains readily in the anterior pituitary gland. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
acidophil cell of pars distalis of adenohypophysis An acidophilic chromophil cell that of the anterior pituitary gland. Synonyms: acidophil cell of pars anterior of adenohypophysis, acidophil of pars anterior of adenohypophysis, acidophil of pars distalis of adenohypophysis, pituitary alpha cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
basophil cell of pars distalis of adenohypophysis A basophilic chromophil cell that of the anterior pituitary gland. Synonyms: basophil cell of anterior lobe of hypophysis http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
chromophobe cell A cell that is resistant to stains. Synonyms: chromophobic cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
folliculostellate cell An agranular supporting cell of the anterior pituitary (adenohypophysis) that is characterized by a star-like morphology and ability to form follicles. Folliculostellate cells communicate with each other and with endocrine cells via gap junctions. Synonyms: folliculo-stellate cell, pituitary folliculostellate cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Bergmann glial cell Type of radial astrocyte in the cerebellar cortex that have their cell bodies in the Purkinje cell layer and processes that extend into the molecular layer, terminating with bulbous endfeet at the pial surface. Bergmann glia express high densities of glutamate transporters that limit diffusion of the neurotransmitter glutamate during its release from synaptic terminals. Besides their role in early development of the cerebellum, Bergmann glia are also required for the pruning or addition of synapses. Synonyms: Bergmann astrocyte, Bergmann glial cell of cerebellum http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pituicyte A glial cell of astrocytic lineage with long processes running parallel to adjacent axons in the proximal infundibulum of the neurohypophysis. These processes form a three-dimensional network among the axons of the hypothalamic neurosecretory cells and are connected by gap junctions which provide for their metabolic coupling. This cell type constitutes most of the nonexcitable tissue in the neurohypophsis; function may include possibly acting as an intermediate in the modulation of oxytocin and vasopressin release. This cell type is highly variable in size and shape and commonly contain lipid droplets and deposits of lipochrome pigment. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
basal cell Undifferentiated; mitotic stem cell for other epithelial cell types; rounded or elliptical with little cytoplasm and few organelles; contain cytokeratin intermediate filament. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
multinucleated giant cell A phagocytic syncytial cell formed by the fusion of macrophages, occurs in chronic inflammatory responses to persistent microorganism such as M.tuberculosis, component of granulomas. Sometimes used to refer to megakaryocytes. Synonyms: Langerhans giant cell, foreign body giant cell, macrophage polykaryon, multinucleate giant cell, syncytial giant cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney granular cell A smooth muscle cell that synthesizes, stores, and secretes the enzyme renin. This cell type are located in the wall of the afferent arteriole at the entrance to the glomerulus. While having a different origin than other kidney smooth muscle cells, this cell type expresses smooth muscle actin upon maturation. Synonyms: JG cell, renin secreting cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
spinous cell of epidermis A keratinocyte found within the stratum spinosum (prickle cell layer) of the epidermis, distinguished by numerous intercellular desmosomes, which give it a “prickly” or spiny appearance. Positioned above the mitotically active basal layer and beneath the granular layer, it contributes to the skin’s mechanical strength and barrier function, preventing water loss and pathogen entry. This cell expresses differentiation-specific keratins K1 and K10 in mice, unlike basal cells that express K5 and K14, and lacks the keratohyalin granules found in granular cells, marking its intermediate stage of epidermal differentiation. Synonyms: prickle cell of epidermis, spinous keratinocytes of epidermis http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesangial cell A cell type that encapsulates the capillaries and venules in the kidney. This cell secretes mesangial matrix that provides the structural support for the capillaries. Synonyms: kidney mesangial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pinealocyte This cell type produces and secretes melatonin and forms the pineal parenchyma. Extending from each cell body, which has a spherical, oval or lobulated mucleus, are one or more tortuous basophilic processes, containing parallel microtubules known as synaptic ribbons. These processes end in expanded terminal buds near capillaries or less, frequently, ependymal cells of the pineal recess. The terminal buds contain granular endoplasmic reticulum, mitochondria and electron-dense cored vesicles, which store monoamines and polypeptide hormones, release of which appears to require sympathetic innervation. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
podocyte A specialized kidney epithelial cell, contained within a glomerulus, that contains "feet" that interdigitate with the "feet" of other podocytes. Synonyms: glomerular podocyte, glomerular visceral epithelial cell, kidney podocyte, renal podocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
primary oocyte A primary oocyte is an oocyte that has not completed female meosis I. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
secondary oocyte A secondary oocyte is an oocyte that has not completed meiosis II. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
primary spermatocyte A diploid cell that has derived from a spermatogonium and can subsequently begin meiosis and divide into two haploid secondary spermatocytes. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
secondary spermatocyte One of the two haploid cells into which a primary spermatocyte divides, and which in turn gives origin to spermatids. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cuticle secreting cell An epithelial cell that secretes cuticle. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
eggshell secreting cell An extracellular matrix secreting cell that secretes eggshell. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
glycocalyx secreting cell An extracellular matrix secreting cell that secretes glycocalyx. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fenestrated endothelial cell An endothelial cell that has small pores, or fenestrations, which allow for the efficient exchange of substances between the blood and surrounding tissues. Synonyms: window cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
collagen secreting cell An extracellular matrix secreting cell that secretes collagen. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pericyte An elongated, contractile cell found wrapped about precapillary arterioles outside the basement membrane. Pericytes are present in capillaries where proper adventitia and muscle layer are missing (thus distingushing this cell type from adventitial cells). They are relatively undifferentiated and may become fibroblasts, macrophages, or smooth muscle cells. Synonyms: ARC, adventitial reticular cell, cell of Rouget, pericyte cell, pericyte of Rouget http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
female gamete A mature sexual reproductive cell of the female germline. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cap cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
gut absorptive cell Cell of the intestinal epithelium with a brush border made up of many parallel packed microvilli; associated with absorption, particularly of macromolecules. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
muscle precursor cell A non-terminally differentiated cell that is capable of developing into a muscle cell. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
radial glial cell A cell present in the developing CNS. Functions as both a precursor cell and as a scaffold to support neuronal migration. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
M cell of gut An absorptive cell of the gut epithelium that endocytoses microorganisms and intact macromolecules from the gut lumen and transports them to the subepithelial space where they are presented to antigen-presenting cells and lymphocytes. Synonyms: M-cell, microfold cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ependymoglial cell A cell that transports hormones from neurosecretory cells. This nerve cell is characterized by bipolar shape and endfeet that contact a basal lamina around blood vessels, and/or the pia mater or vitreous body of the eye and additionally contact the ventricular surface or sub-retinal space. Synonyms: ependymal astrocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
littoral cell of liver http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cerebrospinal fluid secreting cell A columnar/cuboidal epithelial cell that secretes cerebrospinal fluid. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
perijunctional fibroblast A fibroblast-like cell that provides support at neuromuscular junctions in vertebrates and are localized outside the synaptic basal lamina. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myoendocrine cell A cell with both myofibrils and secretory granules. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
terminal Schwann cell A neuroglial cell of the peripheral nervous system inside the basal lamina of the neuromuscular junction providing chemical and physical support to the synapse. Synonyms: perisynaptic Schwann cell, teloglia http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Cajal-Retzius cell A type of transient, early-born glutamatergic neuron located primarily in the marginal zone (future layer I) of the developing cerebral cortex and hippocampus in vertebrates. it is characterized by a bipolar morphology with an elongated soma, a single thick dendrite oriented toward the pial surface, and a long, thin axon that extends tangentially to form horizontal plexuses across the cortical surface. It is important for the multiple developmental processes including migration, dendritogenesis and synaptogenesis. It typically undergoes programmed cell death following cortical maturation with species- and region specific patterns of survival. In mice, it is predominantly observed in the hippocampal formation, particularly in the stratum lacunosum-moleculare and outer molecular layer of the dentate gyrus (van Bruggen et al., 2023). In contrast, in humans, a second morphologically distinct subpopulation emerges mid-gestation and persists postnatally, with surviving cells observed in the cortical sulci and the hippocampus. Synonyms: CR cells, Horizontal cells of Cajal http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
PP cell A cell that stores and secretes pancreatic polypeptide hormone. Synonyms: type F enteroendocrine cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
paraganglial type 1 cell A type of glomus or chief cell, is sensitive to hypoxia and produce catecholamines. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
paraganglia type 2 cell Supports paraganglial type 1 cell. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
sustentacular cell Cell that provides some or all mechanical, nutritional and phagocytic support to their neighbors. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endothelial tip cell A specialized endothelial cell that senses extracellular signals and guides the directed growth of blood vessels. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
choroid plexus epithelial cell A specialized ependymal cell that is part of the choroid plexus epithelium, responsible for producing cerebrospinal fluid (CSF) by selectively filtering and modifying blood plasma components before secreting it into the brain and spinal cord. This cell is characterized by a brush border on its apical surface, which enhances the secretion of CSF. Synonyms: epithelial cell of choroid plexus http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
leptomeningeal cell Stromal cell that forms the internal covering of the vertebrate brain and produces ECM for this and the choroid plexus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
neurecto-epithelial cell Epithelial cells derived from neural plate and neural crest. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cumulus granulosa cell Cumulus cell is a specialized granulosa cell that surrounds and nourishes the oocyte. This cell-type surrounds the fully-grown oocyte to form a cumulus-oocyte complex (abbr. COC). The terms cumulus oophorus cells, cumulus granulosa cells, cumulus oophorous granulosa cells, granulosa-cumulus cells are used to make a distinction between this cell and the other functionally different subpopulation of granulosa cells at the wall of the Graafian follicle. Synonyms: cumulus cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stratum granulosum cell Any epidermal cell that is part of some stratum granulosum of epidermis. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
corona radiata cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
somatic stem cell A stem cell that can give rise to cell types of the body other than those of the germ-line. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
nitrogen fixing cell Any cell that is capable of some nitrogen fixation. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
leading edge cell A cell at the front of a migrating epithelial sheet. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
urothelial cell A cell of a layer of transitional epithelium in the wall of the proximal urethra, bladder, ureter or renal pelvis, external to the lamina propria. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
amoeboid cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
striated muscle cell Muscle cell which has as its direct parts myofilaments organized into sarcomeres. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
leukocyte An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. Synonyms: WBC, leucocyte, white blood cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
retinal ganglion cell The set of neurons that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve. Synonyms: gangliocyte, ganglion cell of retina http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
periarticular chondrocyte A round chondrocyte that first differentiates in the late embryonic growth plate of bone. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hypertrophic chondrocyte A chondrocyte that is part of the hypertrophic cartilage zone. This cell is significantly enlarged and characterised by high expression of type X collagen (COL10A1) in both humans and mice. It actively coordinates endochondral ossification by mineralising the extracellular matrix, attracting blood vessels via angiogenic signalling, and mediating the transition from cartilage to bone - often by transdifferentiating into an osteoblast rather than undergoing apoptosis. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
columnar chondrocyte A columnar chondrocyte that differentiates in the late embryonic growth plate of bone. Columnar chondrocytes vigorously proliferate and form columns in the growth plate. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
retina horizontal cell A neuron that laterally connects other neurons in the inner nuclear layer of the retina. Synonyms: horizontal cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cardiac muscle cell Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. In mammals, the contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei. Synonyms: cardiac muscle fiber, cardiac myocyte, cardiomyocyte, heart muscle cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cyanophore A pigment cell derived from the neural crest. Contains blue pigment of unknown chemical composition in fibrous organelles termed cyanosomes. This gives a blue appearance. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ON-bipolar cell A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the inner half of the inner plexiform layer. These cells depolarize in response to light stimulation of their corresponding photoreceptors. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
OFF-bipolar cell A bipolar neuron found in the retina and having connections with photoreceptors cells and neurons in the outer half of the inner plexiform layer. These cells depolarize in response to light to dark transition. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
rod bipolar cell A bipolar neuron found in the retina that is synapsed by rod photoreceptor cells but not by cone photoreceptor cells. These neurons depolarize in response to light. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cone retinal bipolar cell A bipolar neuron found in the retina and having connections with cone photoreceptor cells and neurons in the inner plexiform layer. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
nucleated thrombocyte A nucleated blood cell involved in coagulation, typically seen in birds and other non-mammalian vertebrates. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myeloid cell A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
erythroid lineage cell A immature or mature cell in the lineage leading to and including erythrocytes. Synonyms: erythropoietic cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
erythroblast A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers. Synonyms: normoblast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myeloid leukocyte A cell of the monocyte, granulocyte, or mast cell lineage. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
basophil Any of the immature or mature forms of a granular leukocyte that in its mature form has an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse, bluish-black granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. A basophil is CD123-positive, CD193-positive, CD203c-positive, and FceRIa-positive. Synonyms: basophilic leucocyte, basophilic leukocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature basophil Any of the immature forms of a basophil, in which basophilic specific granules are present but other phenotypic features of the mature form may be lacking. Synonyms: immature basophilic leucocyte, immature basophilic leukocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
basophilic metamyelocyte A basophil precursor in the granulocytic series, being a cell intermediate in development between a basophilic myelocyte and a band form basophil. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare. Markers are CD11b-positive, CD15-positive, CD16-positive, CD24-positive, CD33-positive, and CD13-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
band form basophil A late basophilic metamyelocyte in which the nucleus is in the form of a curved or coiled band, not having acquired the typical multilobar shape of the mature basophil. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
eosinophil Any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Eosinophils are CD9-positive, CD191-positive, and CD193-positive. Synonyms: eosinocyte, eosinophilic granulocyte, eosinophilic leucocyte, eosinophilic leukocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature eosinophil Any of the immature forms of an eosinophil, in which eosinophilic specific granules are present but other phenotypic features of the mature form may be lacking. Synonyms: immature eosinocyte, immature eosinophilic leucocyte, immature eosinophilic leukocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
eosinophilic metamyelocyte A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a eosinophilic myelocyte and a band form eosinophil. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare. Markers are integrin alpha-M-positive, fucosyltransferase FUT4-positive, low affinity immunoglobulin gamma Fc region receptor III-positive, CD33-positive, CD24-positive and aminopeptidase N-negative. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
band form eosinophil A late eosinophilic metamyelocyte in which the nucleus is in the form of a curved or coiled band, not having acquired the typical multilobar shape of the mature eosinophil. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
neutrophil Any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes. Synonyms: neutrocyte, neutrophil leucocyte, neutrophil leukocyte, neutrophilic leucocyte, neutrophilic leukocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature neutrophil Any of the immature forms of a neutrophil in which neutrophilic specific granules are present but other phenotypic features of the mature form may be lacking. Synonyms: immatuer neutrophilic leukocyte, immature neutrocyte, immature neutrophil leucocyte, immature neutrophil leukocyte, immature neutrophilic leucocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesangial phagocyte A tissue-resident macrophage of the renal glomerular mesangium involved in the disposal and degradation of filtration residues, presentation of antigen to T cells and in tissue remodeling. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mononuclear osteoclast A specialized mononuclear osteoclast associated with the absorption and removal of bone, precursor of multinuclear osteoclasts. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
multinuclear osteoclast A specialized multinuclear osteoclast, forming a syncytium through the fusion of mononuclear precursor cells, associated with the absorption and removal of bone. Synonyms: multinucleated osteoclast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
multinuclear odontoclast A specialized multinuclear osteoclast associated with the absorption and removal of cementum. Synonyms: multinucleated odontoclast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mononuclear odontoclast A specialized mononuclear osteoclast associated with the absorption and removal of cementum. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myeloid dendritic cell A dendritic cell of the myeloid lineage. Synonyms: CD11c+CD123- DC, mDC http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
multinucleated phagocyte A phagocyte formed by the fusion of mononuclear phagocytes. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
plasmacytoid dendritic cell A dendritic cell type of distinct morphology, localization, and surface marker expression (CD123-positive) from other dendritic cell types and associated with early stage immune responses, particularly the release of physiologically abundant amounts of type I interferons in response to infection. Synonyms: DC2, IPC, T-associated plasma cell, interferon-producing cell, lymphoid dendritic cell, pDC, plasmacytoid T cell, plasmacytoid monocyte, type 2 DC http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature B cell A B cell that is mature, having left the bone marrow. Initially, these cells are IgM-positive and IgD-positive, and they can be activated by antigen. Synonyms: mature B lymphocyte, mature B-cell, mature B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
plasma cell A terminally differentiated, post-mitotic, antibody secreting cell of the B cell lineage with the phenotype CD138-positive, surface immunonoglobulin-negative, and MHC Class II-negative. Plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern and are devoted to producing large amounts of immunoglobulin. Synonyms: plasma B cell, plasma B-cell, plasmacyte, plasmocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
memory B cell A memory B cell is a mature B cell that is long-lived, readily activated upon re-encounter of its antigenic determinant, and has been selected for expression of higher affinity immunoglobulin. This cell type has the phenotype CD19-positive, CD20-positive, MHC Class II-positive, and CD138-negative. Synonyms: memory B lymphocyte, memory B-cell, memory B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
naive B cell A naive B cell is a mature B cell that has the phenotype surface IgD-positive, surface IgM-positive, CD20-positive, CD27-negative and that has not yet been activated by antigen in the periphery. Synonyms: naive B lymphocyte, naive B-cell, naive B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
alpha-beta T cell A T cell that expresses an alpha-beta T cell receptor complex. Synonyms: alpha-beta T lymphocyte, alpha-beta T-cell, alpha-beta T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature alpha-beta T cell An alpha-beta T cell that has an immature phenotype and has not completed T cell selection. Synonyms: immature alpha-beta T lymphocyte, immature alpha-beta T-cell, immature alpha-beta T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature alpha-beta T cell A alpha-beta T cell that has a mature phenotype. Synonyms: mature alpha-beta T lymphocyte, mature alpha-beta T-cell, mature alpha-beta T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD4-positive, CD25-positive, alpha-beta regulatory T cell A CD4-positive, CD25-positive, alpha-beta T cell that regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release. Synonyms: CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte, CD4-positive, CD25-positive, alpha-beta regulatory T-cell, CD4-positive, CD25-positive, alpha-beta regulatory T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD4-positive, alpha-beta intraepithelial T cell A CD4-positive, alpha-beta T cell that is found in the columnar epithelium of the gastrointestinal tract. Synonyms: CD4-positive, alpha-beta intraepithelial T lymphocyte, CD4-positive, alpha-beta intraepithelial T-cell, CD4-positive, alpha-beta intraepithelial T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD8-positive, alpha-beta cytotoxic T cell A CD8-positive, alpha-beta T cell that is capable of killing target cells in an antigen specific manner with the phenotype perforin-positive and granzyme B-positive. Synonyms: CD8-positive, alpha-beta cytotoxic T lymphocyte, CD8-positive, alpha-beta cytotoxic T-cell, CD8-positive, alpha-beta cytotoxic T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD8-positive, alpha-beta regulatory T cell A CD8-positive, alpha-beta T cell that regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release. Synonyms: CD8+ T(reg), CD8+ Treg, CD8+ regulatory T cell, CD8-positive T(reg), CD8-positive Treg, CD8-positive, alpha-beta Treg, CD8-positive, alpha-beta regulatory T lymphocyte, CD8-positive, alpha-beta regulatory T-cell, CD8-positive, alpha-beta regulatory T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD8-alpha-beta-positive, alpha-beta intraepithelial T cell A alpha-beta intraepithelial T cell found in the columnar epithelium of the gastrointestinal tract. Intraepithelial T cells often have distinct developmental pathways and activation requirements. Synonyms: CD8-positive, alpha-beta intraepithelial T lymphocyte, CD8-positive, alpha-beta intraepithelial T-cell, CD8-positive, alpha-beta intraepithelial T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
alpha-beta intraepithelial T cell A mature alpha-beta T cell of the columnar epithelium of the gastrointestinal tract. Intraepithelial T cells often have distinct developmental pathways and activation requirements. Synonyms: alpha-beta intraepithelial T lymphocyte, alpha-beta intraepithelial T-cell, alpha-beta intraepithelial T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
gamma-delta T cell A T cell that expresses a gamma-delta T cell receptor complex. Synonyms: gamma-delta T lymphocyte, gamma-delta T-cell, gamma-delta T-lymphocyte, gammadelta T cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature gamma-delta T cell A gamma-delta T cell that has an immature phenotype. Synonyms: immature gamma-delta T lymphocyte, immature gamma-delta T-cell, immature gamma-delta T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature gamma-delta T cell A gamma-delta T cell that has a mature phenotype. These cells can be found in tissues and circulation where they express unique TCR repertoire depending on their location. Synonyms: mature gamma-delta T lymphocyte, mature gamma-delta T-cell, mature gamma-delta T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
gamma-delta intraepithelial T cell A mature gamma-delta T cell that is found in the columnar epithelium of the gastrointestinal tract. These cells participate in mucosal immune responses. Synonyms: gamma-delta intraepithelial T lymphocyte, gamma-delta intraepithelial T-cell, gamma-delta intraepithelial T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD8-alpha alpha positive, gamma-delta intraepithelial T cell A gamma-delta intraepithelial T cell that has the phenotype CD8-alpha alpha-positive. Synonyms: CD8-positive, gamma-delta intraepithelial T lymphocyte, CD8-positive, gamma-delta intraepithelial T-cell, CD8-positive, gamma-delta intraepithelial T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD4-negative CD8-negative gamma-delta intraepithelial T cell A gamma-delta intraepithelial T cell that has the phenotype CD4-negative and CD8-negative. Synonyms: CD4-positive, gamma-delta intraepithelial T lymphocyte, CD4-positive, gamma-delta intraepithelial T-cell, CD4-positive, gamma-delta intraepithelial T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature single positive thymocyte A thymocyte that has the phenotype CD4-negative, CD8-positive, CD44-negative, CD25-negative, and pre-TCR-positive. Synonyms: ISP, T.ISP.th, immature single positive T cell, immature single positive T lymphocyte, immature single positive T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
DN2 thymocyte A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-positive, and CD25-positive. Synonyms: DN2 alpha-beta immature T lymphocyte, DN2 alpha-beta immature T-cell, DN2 alpha-beta immature T-lymphocyte, DN2 cell, DN2 immature T cell, TN2 cell, TN2 thymocyte, double negative 2, preT.DN2.Th http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
DN3 thymocyte A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-negative, and CD25-positive and expressing the T cell receptor beta-chain in complex with the pre-T cell receptor alpha chain. Synonyms: DN3 alpha-beta immature T lymphocyte, DN3 alpha-beta immature T-cell, DN3 alpha-beta immature T-lymphocyte, DN3 cell, DN3 immature T cell, TN3 cell, TN3 thymocyte, double negative 3, preT.DN3.Th http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
DN4 thymocyte A thymocyte that has the phenotype CD4-negative, CD8-negative, CD44-negative, CD25-negative, and pre-TCR-positive. Synonyms: DN4 alpha-beta immature T lymphocyte, DN4 alpha-beta immature T-lymphocyte, DN4 cell, DN4 immature T cell, DN4 immature T-cell, T.DN4.th, double negative 4 http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
double-positive, alpha-beta thymocyte A thymocyte expressing the alpha-beta T cell receptor complex as well as both the CD4 and CD8 coreceptors. Synonyms: DP cell, DP thymocyte, double-positive, alpha-beta immature T lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD4-positive, alpha-beta thymocyte An immature alpha-beta T cell that is located in the thymus and is CD4-positive and CD8-negative. Synonyms: CD4-positive, alpha-beta immature T lymphocyte, CD4-positive, alpha-beta immature T-cell, CD4-positive, alpha-beta immature T-lymphocyte, SP CD4 cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD8-positive, alpha-beta thymocyte An immature alpha-beta T cell that is located in the thymus and is CD8-positive and CD4-negative. Synonyms: CD8-positive, alpha-beta immature T lymphocyte, CD8-positive, alpha-beta immature T-cell, CD8-positive, alpha-beta immature T-lymphocyte, SP CD8 cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
memory T cell A long-lived, antigen-experienced T cell that has acquired a memory phenotype including distinct surface markers and the ability to differentiate into an effector T cell upon antigen reexposure. Synonyms: memory T lymphocyte, memory T-cell, memory T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature NK T cell A mature alpha-beta T cell of a distinct lineage that bears natural killer markers and a T cell receptor specific for a limited set of ligands. NK T cells have activation and regulatory roles particularly early in an immune response. Synonyms: mature NK T lymphocyte, mature NK T-cell, mature NK T-lymphocyte, mature NKT cell, mature natural killer T cell, mature natural killer T lymphocyte, mature natural killer T-cell, mature natural killer T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
regulatory T cell A T cell which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release. Synonyms: Treg, regulatory T lymphocyte, regulatory T-cell, regulatory T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature B cell An immature B cell is a B cell that has the phenotype surface IgM-positive and surface IgD-negative, and have not undergone class immunoglobulin class switching or peripheral encounter with antigen and activation. Synonyms: immature B lymphocyte, immature B-cell, immature B-lymphocyte, newly formed B cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
precursor B cell A precursor B cell is a B cell with the phenotype CD10-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
transitional stage B cell An immature B cell of an intermediate stage between the pre-B cell stage and the mature naive stage with the phenotype surface IgM-positive and CD19-positive, and are subject to the process of B cell selection. A transitional B cell migrates from the bone marrow into the peripheral circulation, and then to the spleen. Synonyms: transitional B cell, transitional stage B lymphocyte, transitional stage B-cell, transitional stage B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
B-1 B cell A B cell of distinct lineage and surface marker expression. B-1 B cells are thought to be the primary source of natural IgM immunoglobulin, that is, IgM produced in large quantities without prior antigenic stimulation and generally reactive against various microorganisms, as well as the source of T-independent IgA immunoglobulin in the mucosal areas. These cells are CD43-positive. Synonyms: B-1 B lymphocyte, B-1 B-cell, B-1 B-lymphocyte, B-1 cell, B1 B cell, B1 B lymphocyte, B1 B-cell, B1 B-lymphocyte, B1 cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
B-1a B cell A B-1 B cell that has the phenotype CD5-positive. Synonyms: B-1a B lymphocyte, B-1a B-cell, B-1a B-lymphocyte, B1a B cell, B1a B lymphocyte, B1a B-cell, B1a B-lymphocyte, B1a cell, CD5(+) B1 cell, CD5+ B1 cell, CD5-positive B1 cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
B-1b B cell A B-1 B cell that has the phenotype CD5-negative, but having other phenotypic attributes of a B-1 B cell. Synonyms: B-1b B lymphocyte, B-1b B-cell, B-1b B-lymphocyte, B1b B cell, B1b B lymphocyte, B1b B-cell, B1b B-lymphocyte, B1b cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
B-2 B cell A conventional B cell subject to antigenic stimulation and dependent on T cell help and with a distinct surface marker expression pattern from B-1 B cells. These cells are CD43-negative. Synonyms: B-2 B lymphocyte, B-2 B-cell, B-2 B-lymphocyte, B2 B cell, B2 B lymphocyte, B2 B-cell, B2 B-lymphocyte, B2 cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature natural killer cell A natural killer cell that is developmentally immature and expresses natural killer cell receptors (NKR). Synonyms: immature NK cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature natural killer cell A natural killer cell that is developmentally mature and expresses a variety of inhibitory and activating receptors that recognize MHC class I and other stress related molecules. Synonyms: mature NK cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pro-NK cell A lymphoid progenitor cell that is committed to the natural killer cell lineage, expressing CD122 (IL-15) receptor, but lacking many of the phenotypic characteristics of later stages of natural killer cell development such as expression of NK activating and inhibitory molecules. In human this cell has the phenotype CD34-positive, CD45RA-positive, CD10-positive, CD117-negative, and CD161 negative. Synonyms: NKP, natural killer cell progenitor, pro-natural killer cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pro-B cell A progenitor cell of the B cell lineage, with some lineage specific activity such as early stages of recombination of B cell receptor genes, but not yet fully committed to the B cell lineage until the expression of PAX5 occurs. Synonyms: pro-B lymphocyte, pro-B-cell, pro-B-lymphocyte, progenitor B cell, progenitor B lymphocyte, progenitor B-cell, progenitor B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pro-T cell A lymphoid progenitor cell of the T cell lineage, with some lineage specific marker expression, but not yet fully committed to the T cell lineage. Synonyms: pro-T lymphocyte, progenitor T cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
thromboblast A progenitor cell of the thrombocyte, a nucleated blood cell involved in coagulation typically seen in birds and other non-mammalian vertebrates. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
basophilic myeloblast A myeloblast committed to the basophil lineage. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
basophilic promyelocyte A promyelocyte committed to the basophil lineage. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mast cell progenitor A progenitor cell of the mast cell lineage. Markers for this cell are FceRIa-low, CD117-positive, CD9-positive, T1/ST2-positive, SCA1-negative, and lineage-negative. Synonyms: MCP http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
eosinophilic myeloblast A myeloblast committed to the eosinophil lineage. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
eosinophilic promyelocyte A promyelocyte committed to the eosinophil lineage. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
neutrophil progenitor cell A progenitor cell of the neutrophil lineage. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myeloblast The most primitive precursor in the granulocytic series, having fine, evenly distributed chromatin, several nucleoli, a high nuclear-to-cytoplasmic ration (5:1-7:1), and a nongranular basophilic cytoplasm. They reside in the bone marrow. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
promyelocyte A precursor in the granulocytic series, being a cell intermediate in development between a myeloblast and myelocyte, that has distinct nucleoli, a nuclear-to-cytoplasmic ratio of 5:1 to 3:1, and containing a few primary cytoplasmic granules. Markers for this cell are fucosyltransferase FUT4-positive, CD33-positive, integrin alpha-M-negative, low affinity immunoglobulin gamma Fc region receptor III-negative, and CD24-negative. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hematopoietic multipotent progenitor cell A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans. Synonyms: MPP, hemopoietic progenitor cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lymphoid lineage restricted progenitor cell A progenitor cell restricted to the lymphoid lineage. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myeloid lineage restricted progenitor cell A progenitor cell restricted to the myeloid lineage. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature conventional dendritic cell An immature cell of the conventional dendritic cell lineage, characterized by high levels of antigen uptake via endocytosis, macropinocytosis, and phagocytosis, and typically found resident in the tissues. Markers for this cell are CD80-low, CD86-low, and MHC-II-low. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature conventional dendritic cell A mature cell of the conventional dendritic cell lineage, characterized by a high capacity for antigen presentation and typically found in a lymph node. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mononuclear leukocyte A leukocyte with a single non-segmented nucleus in the mature form. Synonyms: mononuclear cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
follicular B cell A resting mature B cell that has the phenotype IgM-positive, IgD-positive, CD23-positive and CD21-positive, and found in the B cell follicles of the white pulp of the spleen or the corticol areas of the peripheral lymph nodes. This cell type is also described as being CD19-positive, B220-positive, AA4-negative, CD43-negative, and CD5-negative. Synonyms: Fo B cell, Fo B-cell, follicular B lymphocyte, follicular B-cell, follicular B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
germinal center B cell A rapidly cycling mature B cell that has distinct phenotypic characteristics and is involved in T-dependent immune responses and located typically in the germinal centers of lymph nodes. This cell type expresses Ly77 after activation. Synonyms: GC B cell, GC B lymphocyte, GC B-cell, GC B-lymphocyte, germinal center B lymphocyte, germinal center B-cell, germinal center B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
marginal zone B cell of spleen A mature B cell that is located in the marginal zone of the spleen with the phenotype CD23-negative and CD21-positive and expressing a B cell receptor usually reactive to bacterial cell wall components or senescent self components such as oxidized-LDL. This cell type is also described as being CD19-positive, B220-positive, IgM-high, AA4-negative, CD35-high. Synonyms: B cell of marginal zone of spleen, marginal zone of spleen B cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
vestibular dark cell An epithelial cell of the vestibular sensory organ that is characterized by intense enzymatic activities and numerous basal membrane infoldings. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
olfactory epithelial supporting cell Olfactory epithelial support cell is a columnar cell that extends from the epithelial free margin to the basement membrane of the olfactory epithelium. This cell type has a large, vertically, elongate, euchromatic nucleus, along with other nuclei, forms a layer superficial to the cell body of the receptor cell; sends long somewhat irregular microvilli into the mucus layer; at the base, with expanded end-feet containing numerous lamellated dense bodies resembling lipofuscin of neurons. Synonyms: olfactory epithelial support cell, olfactory sustentacular cell, supporting cell of olfactory epithelium, sustentaculocyte of olfactory epithelium http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
sensory hair cell Hair cell is a mechanoreceptor cell that is sensitive to movement of the hair-like projections (stereocilia and kinocilia) which relay the information centrally in the nervous system. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
slow muscle myoblast A skeletal muscle myoblast that differentiates into slow muscle fibers. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fast muscle myoblast A skeletal muscle myoblast that differentiates into fast muscle fibers. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
classical monocyte A monocyte that responds rapidly to microbial stimuli by secreting cytokines and antimicrobial factors and which is characterized by high expression of CCR2 in both rodents and humans, negative for the lineage markers CD3, CD19, and CD20, and of larger size than non-classical monocytes. Synonyms: inflammatory monocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
elicited macrophage A macrophage which develops from an inflammatory monocyte and is recruited into the tissues in response to injury and infection as part of an inflammatory response. Markers include CD11b-positive, CD68-positive, and F4/80-positive. Synonyms: free macrophage, wandering histiocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
suppressor macrophage A macrophage that suppresses immune responses. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
M1 macrophage An elicited macrophage that is recruited into the tissues in response to injury and infection as part of an inflammatory response, expresses high levels of pro-inflammatory cytokines, ROS and NO, and shows potent microbicidal activity. Synonyms: classically activated macrophage, inflammatory macrophage http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tissue-resident macrophage A macrophage constitutively resident in a particular tissue under non-inflammatory conditions, and capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells. Synonyms: fixed macrophage, resting histiocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
gastrointestinal tract (lamina propria) macrophage A gut-associated lymphoid tissue macrophage found in lamina propria of the gut. Synonyms: gastrointestinal system (lamina propria) macrophage, macrophage of gastrointestinal system (lamina propria), macrophage of gastrointestinal tract (lamina propria) http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
thymic macrophage A tissue-resident macrophage resident found in the thymus, involved in the clearance of apoptotic thymocytes. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
secondary lymphoid organ macrophage A tissue-resident macrophage found in a secondary lymphoid organ. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lymph node macrophage A secondary lymphoid organ macrophage found in a lymph node. This cell is CD169-high. Synonyms: MF.LN http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tonsillar macrophage A gut-associated lymphoid tissue macrophage found in tonsils. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Peyer's patch macrophage A gut-associated lymphoid tissue macrophage found in the Peyer's patches. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
splenic macrophage A secondary lymphoid organ macrophage found in the spleen. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
splenic marginal zone macrophage A splenic macrophage found in the marginal zone of the spleen, involved in recognition and clearance of particulate material from the splenic circulation. Markers include F4/80-negative, MARCO-positive, SR-A-positive, SIGN-R1-positive, and Dectin2-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
splenic metallophillic macrophage A splenic macrophage found in the areas surrounding the white pulp of the spleen, adjacent to the marginal sinus. Markers include F4/80-negative, Dectin2-low, sialoadhesin-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
splenic red pulp macrophage A splenic macrophage found in the red-pulp of the spleen, and involved in immune responses to blood-borne pathogens and in the clearance of senescent erythrocytes. Markers include F4/80-positive, CD68-positive, MR-positive, Dectin2-positive, macrosialin-positive, and sialoadhesin-low. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
non-classical monocyte A type of monocyte characterized by low expression of CCR2, low responsiveness to monocyte chemoattractant CCL2/MCP1, low phagocytic activity, and decrease size relative to classical monocytes, but increased co-stimulatory activity. May also play a role in tissue repair. Synonyms: patrolling monocyte, resident monocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
splenic white pulp macrophage A splenic macrophage found in the white pulp of the spleen. Markers include F4/80-negative, CD68-positive, and macrosialin-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
splenic tingible body macrophage A splenic white pulp macrophage found in and around the germinal centers of the white pulp of the spleen that participates in phagocytosis of apoptotic B cells from the germinal centers. A marker for a cell of this type is Mertk-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
central nervous system macrophage A tissue-resident macrophage found in the central nervous system. Synonyms: CNS macrophage http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
meningeal macrophage A border associated macrophage that is part of a meninx. This macrophage type is elongated and amoeboid spindle-shaped with limited mobility. This macrophage is highly phagocytic, expresses scavenger receptors, has dynamic protrusions and extends its processes during inflammation. Synonyms: subdural leptomeningeal macrophage, subdural meningeal macrophage http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
choroid plexus macrophage A border associated macrophage found at the interface between the blood and the cerebrospinal fluid in the brain. This central nervous system macrophage has a star-like shaped body and expresses scavenger receptors. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
perivascular macrophage A border associated macrophage that is adjacent to a small blood vessel of a brain. A perivascular macrophage expresses the markers CD14, CD16 and CD163. In homeostatic conditions, this central nervous system macrophage has a non-motile cell body with extending and retracting projections through the blood vessel wall. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
thymic medullary macrophage A thymic macrophage found in the thymic medulla. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
thymic cortical macrophage A thymic macrophage found in the thymic cortex. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mucosa-associated lymphoid tissue macrophage A tissue-resident macrophage found in the mucosa associated lymphoid tissue. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
gut-associated lymphoid tissue macrophage A mucosa-associated lymphoid tissue macrophage found in the mucosa-associated lymphoid tissues of the gut. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
nasal and broncial associated lymphoid tissue macrophage A mucosa-associated lymphoid tissue macrophage found in the nasal and bronchial mucosa-associated lymphoid tissues. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lymph node subcapsular sinus macrophage A lymph node macrophage found in the subcapsular sinus of lymph nodes that participates in sensing, clearance, and antigen presentation of lymph-borne particulate antigens. This macrophage is capable of activating invaraint NKT cells and is CD169-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lymph node tingible body macrophage A lymph node macrophage found in the cortex of lymph nodes, in particular in and around the germinal centers, and that participates in phagocytosis of apoptotic B cells from the germinal centers. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myeloid suppressor cell An immature myeloid leukocyte of heterogeneous phenotype found particularly in cancer and sepsis patients that is capable of suppressing activity of T cells in ex vivo assays. This cell type is CD45-positive, CD11b-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
M2 macrophage An elicited macrophage characterized by low production of pro-inflammatory and Th1 polarizing cytokines and high expression of arginase-1, and associated with tissue remodelling. Synonyms: alternatively activated macrophage http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
foam cell A type of cell containing lipids in small vacuoles and typically seen in atherolosclerotic lesions, as well as other conditions. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle cell derived foam cell A type of foam cell derived from a smooth muscle cell containing lipids in small vacuoles and typically seen in atherolosclerotic lesions, as well as other conditions. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
thymocyte An immature T cell located in the thymus. Synonyms: thymic lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
DN1 thymic pro-T cell A pro-T cell that has the phenotype CD4-negative, CD8-negative, CD44-positive, and CD25-negative. Synonyms: DN1 thymic pro-T lymphocyte, DN1 thymic pro-T-cell, DN1 thymic pro-T-lymphocyte, DN1 thymic progenitor T cell, DN1 thymocyte, double negative 1, preT.DN1.Th http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
naive thymus-derived CD4-positive, alpha-beta T cell An antigen inexperienced CD4-positive, alpha-beta T cell with the phenotype CCR7-positive, CD127-positive and CD62L-positive. This cell type develops in the thymus. This cell type is also described as being CD25-negative, CD62L-high, and CD44-low. Synonyms: T.4Nve.Sp, Th0, naive thymus-derived CD4-positive, alpha-beta T lymphocyte, naive thymus-derived CD4-positive, alpha-beta T-cell, naive thymus-derived CD4-positive, alpha-beta T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
activated CD4-positive, alpha-beta T cell A recently activated CD4-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, and CD25-positive. Synonyms: activated CD4-positive, alpha-beta T lymphocyte, activated CD4-positive, alpha-beta T-cell, activated CD4-positive, alpha-beta T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD4-positive, alpha-beta memory T cell A CD4-positive, alpha-beta T cell that has differentiated into a memory T cell. Synonyms: CD4-positive, alpha-beta memory T lymphocyte, CD4-positive, alpha-beta memory T-cell, CD4-positive, alpha-beta memory T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
naive T cell Mature T cell not yet exposed to antigen with the phenotype CCR7-positive, CD45RA-positive, and CD127-positive. This cell type is also described as being CD25-negative, CD62L-high and CD44-low. Synonyms: naive T lymphocyte, naive T-cell, naive T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
T-helper 17 cell CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive, CXCR3-negative, CCR6-positive, and capable of producing IL-17. Synonyms: IL-17-producing CD4+ T helper, T helper cells type 17, T(H)-17 cell, Th17 CD4+ T cell, Th17 T cell, Th17 T lymphocyte, Th17 T-cell, Th17 T-lymphocyte, Th17 cell, helper T cell type 17 http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
naive thymus-derived CD8-positive, alpha-beta T cell A CD8-positive, alpha-beta T cell that has not experienced activation via antigen contact and has the phenotype CD45RA-positive, CCR7-positive and CD127-positive. This cell type is also described as being CD25-negative, CD62L-high and CD44-low. Synonyms: naive thymus-dervied CD8-positive, alpha-beta T lymphocyte, naive thymus-dervied CD8-positive, alpha-beta T-cell, naive thymus-dervied CD8-positive, alpha-beta T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Tr1 cell CD4-positive alpha-beta T cell with regulatory function that produces IL-10. Synonyms: T-regulatory T cell type 1, Tr1 T cell, Tr1 T lymphocyte, Tr1 T-cell, Tr1 T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
induced T-regulatory cell CD4-positive alpha-beta T cell with the phenotype CD25-positive, CTLA-4-positive, and FoxP3-positive with regulatory function. Synonyms: iTreg, induced Treg, induced regulatory T cell, induced regulatory T lymphocyte, induced regulatory T-cell, induced regulatory T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
natural T-regulatory cell CD4-positive alpha-beta T cell with the phenotype FoxP3-positive, CD25-positive, CD62L-positive, and CTLA-4 positive with regulatory function. Synonyms: nTreg, natural Treg, natural regulatory T cell, natural regulatory T lymphocyte, natural regulatory T-cell, natural regulatory T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
central memory CD4-positive, alpha-beta T cell CD4-positive, alpha-beta memory T cell with the phenotype CCR7-positive, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative. Synonyms: central CD4-positive, alpha-beta memory T cell, central CD4-positive, alpha-beta memory T lymphocyte, central CD4-positive, alpha-beta memory T-cell, central CD4-positive, alpha-beta memory T-lymphocyte, central memory CD4-positive, alpha-beta T lymphocyte, central memory CD4-positive, alpha-beta T-cell, central memory CD4-positive, alpha-beta T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
effector memory CD4-positive, alpha-beta T cell CD4-positive, alpha-beta memory T cell with the phenotype CCR7-negative, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative. Synonyms: effector CD4-positive, alpha-beta memory T cell, effector CD4-positive, alpha-beta memory T lymphocyte, effector CD4-positive, alpha-beta memory T-cell, effector CD4-positive, alpha-beta memory T-lymphocyte, effector memory CD4-positive, alpha-beta T lymphocyte, effector memory CD4-positive, alpha-beta T-cell, effector memory CD4-positive, alpha-beta T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
activated CD8-positive, alpha-beta T cell A CD8-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, CD25-positive, and CCR7-negative. Synonyms: activated CD8-positive, alpha-beta T lymphocyte, activated CD8-positive, alpha-beta T-cell, activated CD8-positive, alpha-beta T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
central memory CD8-positive, alpha-beta T cell CD8-positive, alpha-beta memory T cell with the phenotype CCR7-positive, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative. Synonyms: central CD8-positive, alpha-beta memory T cell, central CD8-positive, alpha-beta memory T lymphocyte, central CD8-positive, alpha-beta memory T-cell, central CD8-positive, alpha-beta memory T-lymphocyte, central memory CD8-positive, alpha-beta T lymphocyte, central memory CD8-positive, alpha-beta T-cell, central memory CD8-positive, alpha-beta T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD8-positive, alpha-beta cytokine secreting effector T cell A CD8-positive, alpha-beta T cell with the phenotype CD69-positive, CD62L-negative, CD127-negative, and CD25-positive, that secretes cytokines. Synonyms: CD8-positive, alpha-beta cytokine secreting effector T lymphocyte, CD8-positive, alpha-beta cytokine secreting effector T-cell, CD8-positive, alpha-beta cytokine secreting effector T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD8-positive, alpha-beta memory T cell A CD8-positive, alpha-beta T cell that has differentiated into a memory T cell. Synonyms: CD8-positive, alpha-beta memory T lymphocyte, CD8-positive, alpha-beta memory T-cell, CD8-positive, alpha-beta memory T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cytotoxic T cell A mature T cell that differentiated and acquired cytotoxic function with the phenotype perforin-positive and granzyme-B positive. Synonyms: cytotoxic T lymphocyte, cytotoxic T-cell, cytotoxic T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
effector T cell A differentiated T cell with ability to traffic to peripheral tissues and is capable of mounting a specific immune response. Synonyms: effector T lymphocyte, effector T-cell, effector T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
helper T cell A effector T cell that provides help in the form of secreted cytokines to other immune cells. Synonyms: T-helper cell, helper T lymphocyte, helper T-cell, helper T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
effector memory CD8-positive, alpha-beta T cell CD8-positive, alpha-beta memory T cell with the phenotype CCR7-negative, CD127-positive, CD45RA-negative, CD45RO-positive, and CD25-negative. Synonyms: effector CD8-positive, alpha-beta memory T cell, effector CD8-positive, alpha-beta memory T lymphocyte, effector CD8-positive, alpha-beta memory T-cell, effector CD8-positive, alpha-beta memory T-lymphocyte, effector memory CD8-positive, alpha-beta T lymphocyte, effector memory CD8-positive, alpha-beta T-cell, effector memory CD8-positive, alpha-beta T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature NK T cell An immature alpha-beta T-cell that express Egr2. These cells give rise to T cells expressing NK markers. Synonyms: immature NK T lymphocyte, immature NK T-cell, immature NK T-lymphocyte, immature NKT cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD8-alpha-alpha-positive, alpha-beta intraepithelial T cell An alpha-beta intraepithelial T cell with the phenotype CD8-alpha-alpha-positive located in the columnar epithelium of the gastrointestinal tract. These cells have a memory phenotype of CD2-negative and CD5-negative. Synonyms: CD8-alpha-alpha-positive, alpha-beta intraepithelial T lymphocyte, CD8-alpha-alpha-positive, alpha-beta intraepithelial T-cell, CD8-alpha-alpha-positive, alpha-beta intraepithelial T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
dendritic epidermal T cell A mature gamma-delta T cell located in the epidermis that regulates wound healing. Synonyms: DETC, dendritic epidermal T lymphocyte, dendritic epidermal T-cell, dendritic epidermal T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Tc1 cell A CD8-positive, alpha-beta positive T cell that has the phenotype T-bet-positive, eomesodermin-positive, CXCR3-positive, CCR6-negative, and is capable of producing interferon-gamma. Synonyms: CD8-positive Th1 cell, T-cytotoxic T cell type 1, Tc1 CD8+ T cell, Tc1 T cell, Tc1 T lymphocyte, Tc1 T-cell, Tc1 T-lymphocyte, Th1 CD8-positive T cell, Th1 non-TFH CD8-positive T cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Tc2 cell A CD8-positive, alpha-beta positive T cell expressing GATA-3 and secreting IL-4. Synonyms: CD8-positive Th2 cell, T-cytotoxic T cell type 2, Tc2 T cell, Tc2 T lymphocyte, Tc2 T-cell, Tc2 T-lymphocyte, Th2 CD8-positive T cell, Th2 non-TFH CD8-positive T cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD8-positive, CD25-positive, alpha-beta regulatory T cell A CD8-positive alpha beta-positive T cell with the phenotype FoxP3-positive and having suppressor function. Synonyms: CD8+CD25+ T cell, CD8+CD25+ T lymphocyte, CD8+CD25+ T(reg), CD8+CD25+ T-cell, CD8+CD25+ T-lymphocyte, CD8+CD25+ Treg, CD8-positive, CD25-positive Treg, CD8-positive, CD25-positive, alpha-beta regulatory T lymphocyte, CD8-positive, CD25-positive, alpha-beta regulatory T-cell, CD8-positive, CD25-positive, alpha-beta regulatory T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD8-positive, CD28-negative, alpha-beta regulatory T cell CD8-positive, alpha-beta positive regulatory T cell with the phenotype CD28-negative and FoxP3-positive. Synonyms: CD8+CD28- T cell, CD8+CD28- T lymphocyte, CD8+CD28- T(reg), CD8+CD28- T-cell, CD8+CD28- T-lymphocyte, CD8+CD28- Treg, CD8-positive, CD28-negative T(reg), CD8-positive, CD28-negative Treg, CD8-positive, CD28-negative, alpha-beta regulatory T lymphocyte, CD8-positive, CD28-negative, alpha-beta regulatory T-cell, CD8-positive, CD28-negative, alpha-beta regulatory T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type I NK T cell An alpha-beta T cell expressing NK cell markers that is CD1d restricted and expresses specific V-alpha chains. NK T cells of this type recognize the glycolipid alpha-galactosylceramide in the context of CD1d. Synonyms: classical NK T cell, type I NK T lymphocyte, type I NK T-cell, type I NK T-lymphocyte, type I NKT cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type II NK T cell An alpha-beta T cell expressing NK call markers that is CD1d restricted and expresses a diverse TCR repertoire. Type II NKT cells do not become activated by alpha-galactosylceramide when presented by CD1d. Synonyms: type II NK T lymphocyte, type II NK T-cell, type II NK T-lymphocyte, type II NKT cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD4-positive type I NK T cell A type I NK T cell that has the phenotype CD4-positive. Synonyms: CD4-positive type I NK T lymphocyte, CD4-positive type I NK T-cell, CD4-positive type I NK T-lymphocyte, CD4-positive type I NKT cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD4-negative, CD8-negative type I NK T cell A type I NK T cell that has the phenotype CD4-negative and CD8-negative. Synonyms: CD4-negative, CD8-negative type I NK T lymphocyte, CD4-negative, CD8-negative type I NK T-cell, CD4-negative, CD8-negative type I NK T-lymphocyte, CD4-negative, CD8-negative type I NKT cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
activated CD4-positive type I NK T cell A type I NK T cell that has been recently activated, secretes interferon-gamma and IL-4, and has the phenotype CD4-positive, CD69-positive, and downregulated NK markers. Synonyms: activated CD4-positive type I NK T lymphocyte, activated CD4-positive type I NK T-cell, activated CD4-positive type I NK T-lymphocyte, activated CD4-positive type I NKT cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD4-positive type I NK T cell secreting interferon-gamma A mature NK T cell that secretes interferon-gamma and enhances type 1 immune responses. Synonyms: CD4-positive type I NK T cell secreting IFN-gamma, CD4-positive type I NK T lymphocyte secreting interferon-gamma, CD4-positive type I NK T-cell secreting interferon-gamma, CD4-positive type I NK T-lymphocyte secreting interferon-gamma, CD4-positive type I NKT cell secreting interferon-gamma http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD4-positive type I NK T cell secreting interleukin-4 A mature NK T cell that predominantly secretes type 2 cytokines such as interleukin-4 and interleukin-13 and enhances type 2 immune responses. Synonyms: CD4-positive type I NK T cell secreting IL-4, CD4-positive type I NK T lymphocyte secreting interleukin-4, CD4-positive type I NK T-cell secreting interleukin-4, CD4-positive type I NK T-lymphocyte secreting interleukin-4, CD4-positive type I NKT cell secreting interleukin-4 http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
activated CD4-negative, CD8-negative type I NK T cell A type I NK T cell that has been recently activated, secretes interferon-gamma and interleukin-4, and has phenotype CD4-negative, CD8-negative, CD69-positive, and downregulated NK markers. Synonyms: activated CD4-negative, CD8-negative type I NK T lymphocyte, activated CD4-negative, CD8-negative type I NK T-cell, activated CD4-negative, CD8-negative type I NK T-lymphocyte, activated CD4-negative, CD8-negative type I NKT cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD4-negative, CD8-negative type I NK T cell secreting interferon-gamma A mature NK T cell that secretes interferon-gamma and enhances Th1 immune responses. Synonyms: CD4-negative, CD8-negative type I NK T cell secreting IFN-gamma, CD4-negative, CD8-negative type I NK T lymphocyte secreting interferon-gamma, CD4-negative, CD8-negative type I NK T-cell secreting interferon-gamma, CD4-negative, CD8-negative type I NK T-lymphocyte secreting interferon-gamma, CD4-negative, CD8-negative type I NKT cell secreting interferon-gamma http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD4-negative, CD8-negative type I NK T cell secreting interleukin-4 A mature NK T cell that secretes interleukin-4 and enhances Th2 immune responses. Synonyms: CD4-negative, CD8-negative type I NK T cell secreting IL-4, CD4-negative, CD8-negative type I NK T lymphocyte secreting interleukin-4, CD4-negative, CD8-negative type I NK T-cell secreting interleukin-4, CD4-negative, CD8-negative type I NK T-lymphocyte secreting interleukin-4, CD4-negative, CD8-negative type I NKT cell secreting interleukin-4 http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
activated type II NK T cell A type II NK T cell that has been recently activated, secretes interferon-gamma and interleukin-4, and has the phenotype CD69-positive and downregulated NK markers. Synonyms: activated type II NK T lymphocyte, activated type II NK T-cell, activated type II NK T-lymphocyte, activated type II NKT cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type II NK T cell secreting interferon-gamma A type II NK T cell that has been recently activated, secretes interferon-gamma, and has the phenotype CD69-positive and downregulated NK markers. Synonyms: type II NK T cell secreting IFN-gamma, type II NK T lymphocyte secreting interferon-gamma, type II NK T-cell secreting interferon-gamma, type II NK T-lymphocyte secreting interferon-gamma, type II NKT cell secreting interferon-gamma http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type II NK T cell secreting interleukin-4 A type II NK T cell that has been recently activated, secretes interleukin-4, and has the phenotype CD69-positive and downregulated NK markers. Synonyms: type II NK T cell secreting IL-4, type II NK T lymphocyte secreting interleukin-4, type II NK T-cell secreting interleukin-4, type II NK T-lymphocyte secreting interleukin-4, type II NKT cell secreting interleukin-4 http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD4-positive, alpha-beta cytotoxic T cell A CD4-positive, alpha-beta T cell that has cytotoxic function. Synonyms: CD4-positive, alpha-beta cytotoxic T lymphocyte, CD4-positive, alpha-beta cytotoxic T-cell, CD4-positive, alpha-beta cytotoxic T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD4-negative, CD8-negative, alpha-beta intraepithelial T cell A CD4-negative, CD8-negative, alpha-beta intraepithelial T cell that is found in the columnar epithelium of the gastrointestinal tract. Synonyms: CD4-negative, CD8-negative, alpha-beta intraepithelial T lymphocyte, CD4-negative, CD8-negative, alpha-beta intraepithelial T-cell, CD4-negative, CD8-negative, alpha-beta intraepithelial T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
early lymphoid progenitor A lymphoid progenitor cell that is found in bone marrow, gives rise to B cells, T cells, natural killer cells and dendritic cells, and has the phenotype Lin-negative, Kit-positive, Sca-1-positive, FLT3-positive, CD34-positive, CD150 negative, and GlyA-negative. Synonyms: lymphoid-primed multipotent progenitor http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pre-natural killer cell Cell committed to natural killer cell lineage that has the phenotype CD122-positive, CD34-positive, and CD117-positive. This cell type lacks expression of natural killer receptor proteins. Synonyms: pre-NK cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD16-negative, CD56-bright natural killer cell, human NK cell that has the phenotype CD56-bright, CD16-negative, and CD84-positive with the function to secrete interferon-gamma but is not cytotoxic. Synonyms: CD16-CD56bright NK cell, CD16-negative, CD56-bright NK cell, CD56-bright cytokine secreting NK cell, CD56-bright cytokine secreting natural killer cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD16-positive, CD56-dim natural killer cell, human A mature natural killer cell that has the phenotype CD56-low, CD16-positive and which is capable of cytotoxicity and cytokine production. Synonyms: CD16+CD56+ NK cell, CD16-positive, CD56-dim NK cell, CD16-positive, CD56-low NK cell, CD16-positive, CD56-low natural killer cell, CD16-positive, CD56-positive NK cell, CD16-positive, CD56-positive natural killer cell, cytotoxic CD56-dim NK cell, cytotoxic CD56-dim natural killer cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mucosal-associated invariant T cell An alpha-beta T cell that is found in the lamina propria of mucosal tissues and is restricted by the MR-1 molecule. This cell develops from double-positive, alpha-beta thymocyte. Synonyms: mucosal invariant T cell, mucosal invariant T lymphocyte, mucosal invariant T-cell, mucosal invariant T-lymphocyte, mucosal-associated invariant T lymphocyte, mucosal-associated invariant T-cell, mucosal-associated invariant T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
thymic conventional dendritic cell A dendritic cell arising in thymus that has the phenotype CD11c-positive, CD11b-negative, and CD45RA-negative. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
thymic plasmacytoid dendritic cell A plasmacytoid dendritic cell developing in the thymus with phenotype CD11c-negative or low, CD45RA-positive, CD11b-negative, and CD123-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Be1 Cell A Be cell that facilitates development of T-helper 1 (Th1) phenotype in CD4-positive T cells, and secretes high levels of interleukin-2, tumor necrosis factor-alpha and interferon-gamma. Synonyms: B effector 1 cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Be2 cell A Be cell that facilitates development of T-helper 2 (Th2) phenotype T cells, and secretes high levels of interleukin-2, interleukin-10, interleukin-4, and interleukin-6. Synonyms: B effector 2 cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lymphocyte of B lineage A lymphocyte of B lineage with the commitment to express an immunoglobulin complex. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
antibody secreting cell A lymphocyte of B lineage that is devoted to secreting large amounts of immunoglobulin. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
IgE plasma cell A long lived plasma cell that secretes IgE. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
IgE memory B cell A class switched memory B cell that expresses IgE on the cell surface. Synonyms: IgE memory B lymphocyte, IgE memory B-cell, IgE memory B-lymphocyte, memory IgE B cell, memory IgE B lymphocyte, memory IgE B-cell, memory IgE B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
IgD plasmablast A plasmablast that secretes IgD, and which occur in a small proportion of B cells in the adult. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
IgE plasmablast A plasmablast that secretes IgE. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
IgE short lived plasma cell A short lived plasma cell that secretes IgE. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
preBCR-positive large pre-B-II cell An preBRC-positive large pre-B-II cell is a large pre-B-II cell that is pre-B cell receptor-positive, composed of surrogate light chain protein (SL), which is composed of VpreB , Lambda 5/14.1, in complex with immunoglobulin mu heavy chain (IgHmu) on the cell surface. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
preBCR-negative large pre-B-II cell A pre-BCR-negative large pre-B-II cell is a large pre-B-II cell that is pre-B cell receptor-negative, composed of surrogate light chain protein (SL), which is composed of VpreB and Lambda 5/14.1, in complex with immunoglobulin mu heavy chain (IgHmu), on the cell surface, and lack a DNA rearrangement of immunoglobulin light chain genes. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
small pre-B-II cell A small pre-B-II cell is a pre-B-II cell that is Rag1-positive, Rag2-positive, pre-BCR-negative, and BCR-negative, is not proliferating, and carries a DNA rearrangement of one or more immunoglobulin light chain genes. Synonyms: small pre-BII cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pre-B-II cell A pre-B-II cell is a precursor B cell that expresses immunoglobulin mu heavy chain (IgHmu+), and lack expression of CD34, TdT, immunoglobulin kappa light chain and immunoglobulin lambda light chain. Synonyms: pre-B-lymphocyte, pre-BII cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pre-B-I cell A pre-B-I cell is a precursor B cell that expresses CD34 and surrogate immunoglobulin light chain (VpreB , Lambda 5 (mouse)/14.1 (human)) on the cell surface, and TdT, Rag1,and Rag2 intracellularly. Cell type carries a D-JH DNA rearrangement, and lacks expression of immunglobulin heavy chain protein. Synonyms: pre-BI cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
large pre-B-II cell A large pre-B-II cell is a pre-B-II cell that is proliferating and is Rag1-negative and Rag2-negative. Synonyms: large pre-BII cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
T1 B cell A transitional stage B cell that migrates from the bone marrow into the peripheral circulation, and finally to the spleen. This cell type has the phenotype surface IgM-positive, surface IgD-negative, CD21-negative, CD23-negative, and CD62L-negative, and CD93-positive. This cell type has also been described as IgM-high, CD19-positive, B220-positive, AA4-positive, and CD23-negative. Synonyms: T1 B lymphocyte, T1 B-cell, T1 B-lymphocyte, transitional stage 1 B cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
T2 B cell A transitional stage B cell that has the phenotype surface IgM-positive, surface IgD-postive, CD21-positive, CD23-positive, CD62L-negative, CD93-positive and is located in the splenic B follicles. This cell type has also been described as IgM-high, CD19-positive, B220-positive, AA4-positive, and CD23-positive. Synonyms: T2 B lymphocyte, T2 B-cell, T2 B-lymphocyte, transitional stage 2 B cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
T3 B cell A transitional stage B cell that expresses surface IgM and IgD, and CD62L. This cell type appears to be an anergic B cell that does not proliferate upon BCR signaling, is found in the spleen and lymph nodes, and has the phenotype surface IgM-positive, surface IgD-positive, CD21-positive, CD23-positive, CD62L-positive, and CD93-positive. This cell type has also been described as IgM-low, CD19-positive, B220-positive, AA4-positive, and CD23-positive (i.e. this cell-type is distinguished from T2 cells by surface expression of IgM). Synonyms: An1 B cell, T3 B lymphocyte, T3 B-cell, T3 B-lymphocyte, transitional stage 3 B cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Bm1 B cell A follicular B cell that is IgD-positive, CD23-negative, and CD38-negative. This naive cell type is activated in the extrafollicular areas through interaction with interdigitating dendritic cells and antigen-specific CD4-positive T cells. Synonyms: Bm1 B lymphocyte, Bm1 B-cell, Bm1 B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Bm2 B cell A follicular B cell that is IgD-positive and CD23-positive and CD38-positive. This naive cell type is activated in the extrafollicular areas via interaction with dendritic cells and antigen specific T cells. Synonyms: Bm2 B lymphocyte, Bm2 B-cell, Bm2 B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Bm3-delta B cell A germinal center B cell that develops from a Bm3 B cell. This cell has the phenotype IgM-negative, IgD-positive, and CD38-positive. Synonyms: Bm3-delta B lymphocyte, Bm3-delta B-cell, Bm3-delta B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Bm2' B cell A germinal center B cell that founds a germinal center, and has the phenotype IgD-positive, CD38-positive, and CD23-negative. Synonyms: Bm2' B lymphocyte, Bm2' B-cell, Bm2-prime B cell, Bm2-prime B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Bm3 B cell A germinal center B cell that is rapidly dividing and has the phenotype IgD-negative, CD38-positive, and CD77-positive. Somatic hypermutation of the immunoglobulin V gene region can occur during proliferation of this cell type. Synonyms: Bm3 B lymphocyte, Bm3 B-cell, Bm3 B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Bm4 B cell A germinal center B cell that has the phenotype CD77-negative, IgD-negative, and CD38-positive. These cells have undergone somatic mutation of the B cell receptor. Synonyms: Bm4 B lymphocyte, Bm4 B-cell, Bm4 B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Bm5 B cell A memory B cell arising in the germinal center that is IgD-negative and has undergone somatic mutation of the variable region of the immunoglobulin heavy and light chain genes. Synonyms: Bm5 B lymphocyte, Bm5 B-cell, Bm5 B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Be cell A mature B cell that produces cytokines that can influence CD4 T cell differentiation. Synonyms: B effector cell, effector B cell, effector B lymphocyte, effector B-cell, effector B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
regulatory B cell A mature B cell that has the phenotype CD1d-positive and expresses interleukin-10. This cell type has been associated with suppression of chronic inflammatory responses and T cell responses. Synonyms: B(reg), B10 cell, Breg, regulatory B lymphocyte, regulatory B-cell, regulatory B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
unswitched memory B cell An unswitched memory B cell is a memory B cell that has the phenotype IgM-positive, IgD-positive, CD27-positive, CD138-negative, IgG-negative, IgE-negative, and IgA-negative. Synonyms: non-class-switched memory B cell, unswitched memory B lymphocyte, unswitched memory B-cell, unswitched memory B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
IgM memory B cell An IgM memory B cell is an unswitched memory B cell with the phenotype IgM-positive and IgD-negative. Synonyms: IgM memory B lymphocyte, IgM memory B-cell, IgM memory B-lymphocyte, memory IgM B cell, memory IgM B lymphocyte, memory IgM B-cell, memory IgM B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
class switched memory B cell A class switched memory B cell is a memory B cell that has undergone Ig class switching and therefore is IgM-negative on the cell surface. These cells are CD27-positive and have either IgG, IgE, or IgA on the cell surface. Synonyms: class switched memory B lymphocyte, class switched memory B-cell, class switched memory B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
IgA memory B cell A class switched memory B cell that expresses IgA. Synonyms: IgA memory B lymphocyte, IgA memory B-cell, IgA memory B-lymphocyte, memory IgA B cell, memory IgA B lymphocyte, memory IgA B-cell, memory IgA B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
long lived plasma cell A fully differentiated plasma cell that lives for years, as opposed to months, secretes immunoglobulin, and has the phenotype weakly CD19-positive, CD20-negative, CD38-negative, strongly CD138-positive, MHC Class II-negative, surface immunoglobulin-negative, IgD-negative, and strongly CXCR4-positive. The majority of these cells of this type reside in the bone marrow. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
short lived plasma cell A fully differentiated plasma cell that lives for months. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
IgA short lived plasma cell A short lived plasma cell that secretes IgA. These cells may be found in the bone marrow as well as in the mucosal immune system. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
IgG short lived plasma cell A short lived plasma cell that secretes IgG. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
IgM short lived plasma cell A short lived plasma cell that secretes IgM. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
IgG memory B cell An IgG memory B cell is a class switched memory B cell that is class switched and expresses IgG on the cell surface. Synonyms: IgG memory B lymphocyte, IgG memory B-cell, IgG memory B-lymphocyte, memory IgG B cell, memory IgG B lymphocyte, memory IgG B-cell, memory IgG B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
plasmablast An activated mature (naive or memory) B cell that is secreting immunoglobulin, typified by being CD27-positive, CD38-positive, CD138-negative. Synonyms: CD27-positive, CD38-positive, CD20-negative B cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
double negative memory B cell A memory B cell with the phenotype IgD-negative and CD27-negative. Synonyms: dn memory B cell, dn memory B lymphocyte, dn memory B-cell, dn memory B-lymphocyte, double negative memory B lymphocyte, double negative memory B-cell, double negative memory B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
IgG plasmablast A plasmablast that secretes IgG. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
IgM plasmablast A plasmablast that secretes IgM. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
IgA plasmablast A plasmablast that secretes IgA. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
IgG plasma cell A fully differentiated plasma cell that secretes IgG. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
IgM plasma cell A fully differentiated plasma cell that secretes IgM. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
IgA plasma cell A fully differentiated plasma cell that secretes IgA. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hematopoietic cell A cell of a hematopoietic lineage. Synonyms: haematopoietic cell, haemopoietic cell, hemopoietic cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
conventional dendritic cell Conventional dendritic cell is a dendritic cell that is CD11c-high. Synonyms: DC1, cDC, dendritic reticular cell, type 1 DC http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD11c-negative plasmacytoid dendritic cell CD11c-negative plasmacytoid dendritic cell is a leukocyte is CD11c-negative, CD45RA-positive, CD85g-positive(ILT7), CD123-positive, CD303-positive. Synonyms: CD303-positive dendritic cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature CD11c-negative plasmacytoid dendritic cell Immature CD11c-negative plasmacytoid dendritic cell is a CD11c-negative plasmacytoid dendritic cell is CD80-negative, CD86-low and MHCII-low. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD34-positive, CD38-positive common myeloid progenitor OR CD34-positive, CD38-positive common lymphoid progenitor http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature CD11c-negative plasmacytoid dendritic cell Mature CD11c-negative plasmacytoid dendritic cell is a CD11c-negative plasmacytoid dendritic cell is CD80-high, CD86-high, MHCII-high and is CD83-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature CD8-alpha-negative CD11b-positive dendritic cell Immature CD8-alpha-negative CD11b-positive dendritic cell is a CD8-alpha-negative CD11b-positive dendritic cell that is CD80-low, CD86-low, and MHCII-low. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD8-alpha-negative CD11b-negative dendritic cell CD8-alpha-negative CD11b-negative dendritic cell is a conventional dendritic cell that is CD11b-negative, CD4-negative CD8-alpha-negative and is CD205-positive. This cell is able to cross- present antigen to CD8-alpha-positive T cells. Synonyms: DC.8-4-11b-, triple negative dendritic cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD4-positive CD11b-positive dendritic cell CD8-alpha-negative CD11b-positive dendritic cell is a conventional dendritic cell that is CD11b-positive, CD4-positive and is CD205-negative and CD8-alpha-negative. Synonyms: DC.4+ http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD8-alpha-positive CD11b-negative dendritic cell CD8-alpha-positive CD11b-negative dendritic cell is a conventional dendritic cell that is CD11b-negative, CD4-negative and is CD205-positive and CD8-alpha-positive. Synonyms: DC.8+ http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature CD8-alpha-negative CD11b-negative dendritic cell Immature CD8-alpha-negative CD11b-negative dendritic cell is a CD8-alpha-negative CD11b-negative dendritic cell that is CD80-low, CD86-low, and MHCII-low. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature CD8-alpha-negative CD11b-negative dendritic cell Mature CD8-alpha-negative CD11b-negative dendritic cell is a CD8-alpha-negative CD11b-negative dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature CD8-alpha-negative CD11b-positive dendritic cell Mature CD8-alpha-negative CD11b-positive dendritic cell is a CD8-alpha-negative CD11b-positive dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature CD8-alpha-positive CD11b-negative dendritic cell Immature CD8-alpha-positive CD11b-negative dendritic cell is a CD8-alpha-positive CD11b-negative dendritic cell that is CD80-low, CD86-low, and MHCII-low. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature CD8-alpha-positive CD11b-negative dendritic cell Mature CD8-alpha-positive CD11b-negative dendritic cell is a CD8-alpha-positive CD11b-negative dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
dermal dendritic cell Dermal dendritic cell is a conventional dendritic cell that is CD11b-positive, CD205-positive and CD8 alpha-negative. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
interstitial dendritic cell Interstitial dendritic cell is a conventional dendritic cell that is CD11b-positive, CD1a-positive, CD206-positive, CD209-positive, and CD36-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Kit and Sca1-positive hematopoietic stem cell A hematopoietic stem cell that has plasma membrane part Kit-positive, SCA-1-positive, CD150-positive and CD34-negative. Synonyms: LSK stem cell, Sca1-positive hematopoietic stem cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature dermal dendritic cell Immature dermal dendritic cell is a dermal dendritic cell that is CD80-low, CD86-low, and MHCII-low. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature dermal dendritic cell Mature dermal dendritic cell is a dermal dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature interstitial dendritic cell Immature interstitial dendritic cell is a interstitial dendritic cell that is CD80-low, CD86-low, and MHCII-low. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD7-negative lymphoid progenitor OR granulocyte monocyte progenitor http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature interstitial dendritic cell Mature interstitial dendritic cell is a interstitial dendritic cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD1a-positive Langerhans cell CD1a-positive Langerhans cell is a Langerhans_cell that is CD1a-positive and CD324-positive. Synonyms: CD1a-LC http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD8-alpha-low Langerhans cell CD8-alpha-low Langerhans cell is a Langerhans cell that is CD205-high and is CD8-alpha-low. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature CD1a-positive Langerhans cell Immature CD1a-positive Langerhans cell is a CD1a-positive Langerhans cell that is CD80-low, CD86-low, and MHCII-low. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature CD1a-positive Langerhans cell Mature CD1a-positive Langerhans cell is a CD1a-positive Langerhans cell that is CD80-high, CD86-high, MHCII-high and is CD83-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature CD8-alpha-low Langerhans cell Immature CD8-alpha-low Langerhans cell is a CD8-alpha-low Langerhans cell that is CD80-low, CD86-low, and MHCII-low. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD115-positive monocyte OR common dendritic progenitor http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature CD8-alpha-low Langerhans cell Mature CD8-alpha-low Langerhans cell is a CD8-alpha-low Langerhans cell that that is CD80-high, CD86-high, MHCII-high and is CD83-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD34-positive, CD38-positive common lymphoid progenitor A common lymphoid progenitor that is CD10-positive, CD45RA-positive, CD34-positive and CD38-positive. Synonyms: CD10-positive common lymphocyte precursor, CD10-positive common lymphocyte progenitor, CD10-positive common lymphoid precursor http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD115-positive monocyte CD115-positive monocyte is a monocyte that is CD115-positive and CD11b-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Kit-positive, CD34-positive common myeloid progenitor A common myeloid progenitor that is Kit-positive and CD34-positive, Il7ra-negative, and is SCA1-low and Fcgr2-low and Fcgr3-low. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD34-positive, CD38-negative hematopoietic stem cell CD133-positive hematopoietic stem cell is a hematopoietic stem cell that is CD34-positive, CD90-positive, and CD133-positive. Synonyms: CD133-positive hematopoietic stem cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Kit-positive, Sca1-positive common lymphoid progenitor A common lymphoid progenitor that is Kit-low, FLT3-positive, IL7ralpha-positive, and SCA1-low. Synonyms: CD217-positive common lymphocyte precursor, CD217-positive common lymphocyte progenitor, CD217-positive common lymphoid precursor http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD34-positive, CD38-positive common myeloid progenitor A common myeloid progenitor that is CD34-positive, CD38-positive, IL3ra-low, CD10-negative, CD7-negative, CD45RA-negative, and IL-5Ralpha-negative. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD7-negative lymphoid progenitor cell CD7-negative lymphoid progenitor cell is a lymphoid progenitor cell that is CD34-positive, CD7-negative and CD45RA-negative. Synonyms: CD7-negative lymphoid precursor http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD7-positive lymphoid progenitor cell CD7-positive lymphoid progenitor cell is a lymphoid progenitor cell that is CD34-positive, CD7-positive and is CD45RA-negative. Synonyms: CD7-positive lymphoid precursor http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
common dendritic progenitor Common dendritic precursor is a hematopoietic progenitor cell that is CD117-low, CD135-positive, CD115-positive and lacks plasma membrane parts for hematopoietic lineage markers. Synonyms: CDP, common dendritic precursor, pro-DCs http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD117-positive common myeloid progenitor OR CD217-positive common lymphoid progenitor http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cerebellar granule cell An excitatory granule cell with a soma located in the granular layer of cerebellar cortex. A mature cerebellar granule cell has short dendrites with a characteristic claw-like appearance and a long axon that ascends to the molecular layer where it bifurcates (except in non-teleost fish, where it does not bifurcate) and extends mediolaterally to form parallel fibers. Synonyms: granule cell of the cerebellum http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cortical granule cell Granule cell that is part of the cerebral cortex. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hippocampal granule cell Granule cell with a soma found in the hippocampus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cell in vitro A cell that is maintained or propagated in a controlled artificial environment for use in an investigation. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
bone cell A connective tissue cell found in bone. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
terminally differentiated osteoblast Osteoblast that is terminally differentiated, located adjacent to acellular or cellular bone tissue within periosteum, and is capable of mineralizing the matrix. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
non-terminally differentiated osteoblast Osteoblast that is non-terminally differentiated and located in cellular bone tissue or under the periosteum in acellular bone. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD8-positive, CXCR3-positive, alpha-beta regulatory T cell A CD8-positive alpha-beta-positive T cell with the phenotype CXCR3-positive and having suppressor function. They are capable of producing IL-10, suppressing proliferation, and suppressing IFN-gamma production. Synonyms: CD8+CXCR3+ T cell, CD8+CXCR3+ T lymphocyte, CD8+CXCR3+ T(reg), CD8+CXCR3+ T-cell, CD8+CXCR3+ Treg, CD8-positive, CXCR3-positive, T(reg), CD8-positive, CXCR3-positive, Treg, CD8-positive, CXCR3-positive, alpha-beta regulatory T lymphocyte, CD8-positive, CXCR3-positive, alpha-beta regulatory T-cell, CD8-positive, CXCR3-positive, alpha-beta regulatory T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
T-helper 22 cell CD4-positive, alpha-beta T cell that produces IL-22. Synonyms: T(H)-22 cell, Th22 T cell, Th22 T lymphocyte, Th22 T-cell, Th22 T-lymphocyte, Th22 cell, helper T cell type 22 http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
activated CD4-positive, alpha-beta T cell, human A recently activated CD4-positive, alpha-beta T cell with the phenotype HLA-DRA-positive, CD38-positive, CD69-positive, CD62L-negative, CD127-negative, and CD25-positive. Synonyms: activated CD4-positive, alpha-beta T lymphocyte, human, activated CD4-positive, alpha-beta T-cell, human, activated CD4-positive, alpha-beta T-lymphocyte, human http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
effector CD4-positive, alpha-beta T cell A CD4-positive, alpha-beta T cell with the phenotype CCR7-negative, CD45RA-positive. Synonyms: effector CD4-positive, alpha-beta T lymphocyte, effector CD4-positive, alpha-beta T-cell, effector CD4-positive, alpha-beta T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
naive CCR4-positive regulatory T cell A naive regulatory T cell with the phenotype CD4-positive, CD25-positive, CD127lo, CCR4-positive, and CD45RO-negative. Synonyms: naive CCR4+ Treg, naive CCR4-positive regulatory T lymphocyte, naive CCR4-positive regulatory T-cell, naive CCR4-positive regulatory T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
memory CCR4-positive regulatory T cell A memory regulatory T cell with phenotype CD4-positive, CD25-positive, CD127lo, CCR4-positive, and CD45RO-positive. Synonyms: memory CCR4+ Treg, memory CCR4-positive regulatory T lymphocyte, memory CCR4-positive regulatory T-cell, memory CCR4-positive regulatory T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T cell A CD4-positive, CD25-positive, alpha-beta regulatory T cell with the additional phenotype CCR4-positive. Synonyms: CCR+ Treg, CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T lymphocyte, CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T-cell, CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
activated CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T cell, human A CD4-positive, CD25-positive, CCR4-positive, alpha-beta T regulatory cell with the phenotype HLA-DRA-positive, indicating recent activation. Synonyms: activated CCR4+ Treg, activated CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T lymphocyte, activated CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T-cell, activated CD4-positive, CD25-positive, CCR4-positive, alpha-beta regulatory T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
activated CD8-positive, alpha-beta T cell, human A recently activated CD8-positive, alpha-beta T cell with the phenotype HLA-DRA-positive, CD38-positive, CD69-positive, CD62L-negative, CD127-negative, CCR7-negative, and CD25-positive. Synonyms: activated CD8-positive, alpha-beta T lymphocyte, human, activated CD8-positive, alpha-beta T-cell, human, activated CD8-positive, alpha-beta T-lymphocyte, human http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
effector CD8-positive, alpha-beta T cell A CD8-positive, alpha-beta T cell with the phenotype CCR7-negative, CD45RA-positive. Synonyms: effector CD8-positive, alpha-beta T lymphocyte, effector CD8-positive, alpha-beta T-cell, effector CD8-positive, alpha-beta T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell A CD4-positive, alpha-beta T cell that has the phenotype CXCR3-negative, CCR6-negative. Synonyms: CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T lymphocyte, CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T-cell, CD4-positive, CXCR3-negative, CCR6-negative, alpha-beta T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T cell A CD8-positive, alpha-beta T cell that has the phenotype CXCR3-negative, CCR6-negative. Synonyms: CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T lymphocyte, CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T-cell, CD8-positive, CXCR3-negative, CCR6-negative, alpha-beta T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
IgD-negative memory B cell A memory B cell that lacks expression of surface IgD. Synonyms: IgD- memory B cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD14-positive monocyte A monocyte that expresses CD14 and is negative for the lineage markers CD3, CD19, and CD20. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD14-positive, CD16-low monocyte An intermediate monocyte that is CD14-positive and with low amounts of CD16. Synonyms: intermediate monocyte, human http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
dendritic cell, human A dendritic cell with the phenotype HLA-DRA-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myeloid dendritic cell, human A myeloid dendritic cell with the phenotype HLA-DRA-positive and CD14-negative. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
plasmacytoid dendritic cell, human A plasmacytoid dendritic cell with the phenotype HLA-DRA-positive, CD123-positive, CD11c-negative, and CD14-negative. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
common myeloid progenitor, CD34-positive A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages. These cells are CD34-positive, and express Gata1, Gata2, C/EBPa, and Pu.1. Synonyms: common myeloid precursor, CD34-positive http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hematopoietic oligopotent progenitor cell, lineage-negative A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. Cell lacks hematopoeitic lineage markers. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
abnormal cell A cell found in an organism or derived from an organism exhibiting a phenotype that deviates from the expected phenotype of any native cell type of that organism. Abnormal cells are typically found in disease states or disease models. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
effector memory CD8-positive, alpha-beta T cell, terminally differentiated A CD8-positive, alpha beta memory T cell with the phenotype CD45RA-positive, CD45RO-negative, and CCR7-negative. Synonyms: CD8+ TEMRA, CD8-positive TEMRA http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
neoplastic cell An abnormal cell exhibiting dysregulation of cell proliferation or programmed cell death and capable of forming a neoplasm, an aggregate of cells in the form of a tumor mass or an excess number of abnormal cells (liquid tumor) within an organism. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
malignant cell A neoplastic cell that is capable of entering a surrounding tissue http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
innate lymphoid cell A lymphocyte that lacks characteristic T cell, B cell, myeloid cell, and dendritic cell markers, that functions as part of the innate immune response to produce cytokines and other effector responses. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
erythroid progenitor cell, mammalian A progenitor cell committed to the erythroid lineage. This cell is ter119-positive but lacks expression of other hematopoietic lineage markers (lin-negative). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
group 1 innate lymphoid cell An innate lymphoid cell that is capable of producing the type 1 cytokine IFN-gamma, but not Th2 or Th17 cell-associated cytokines. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ILC1 A group 1 innate lymphoid cell that is non-cytotoxic. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
group 2 innate lymphoid cell An innate lymphoid cell that is capable of producing T-helper 2-cell associated cytokines upon stimulation. Synonyms: ILC2, natural helper cell, nuocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
beige adipocyte An adipocyte that is beige in color, thermogenic, and which differentiates in white fat tissue from a Myf5-negative progenitor. Synonyms: beige brown adipocyte, beige fat cell, beige/brite adipocyte, brite adipocyte, brite cell, brite fat cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
group 3 innate lymphoid cell An innate lymphoid cell that constituitively expresses RORgt and is capable of expressing IL17A and/or IL-22. Synonyms: ILC3 http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD34-negative, CD117-positive innate lymphoid cell, human An innate lymphoid cell in the human with the phenotype CD34-negative, CD117-positive, and a precusor to NK cells, ILC2 cells, and ILC3 cells. Synonyms: CD34-negative, CD117-positive ILC, CD34-negative, CD117-positive ILCP, CD34-negative, CD117-positive innate lymphoid cell precusor http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD34-negative, CD56-positive, CD117-positive innate lymphoid cell, human An innate lymphoid cell in the human with the phenotype CD34-negative, CD56-positive, CD117-positive.Thie cell type may include precusors to NK cells and ILC3 cells. Synonyms: CD34-negative, CD56-positive, CD117-positive ILC, CD34-negative, CD56-positive, CD117-positive ILCP, CD34-negative, CD56-positive, CD117-positive innate lymphoid cell precursor http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD34-positive, CD56-positive, CD117-positive common innate lymphoid precursor, human An innate lymphoid cell precursor in the human with the phenotype CD34-positive, CD56-positive, CD117-positive.Thie cell type may include precusors to NK cells and ILC3 cells. Synonyms: CD34-positive, CD56-positive, CD117-positive CILP http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
KLRG1-positive innate lymphoid cell, human An innate lymphoid cell in the human with the phenotype KLRG1-positive that is a precusor for ILC2 cells. Synonyms: KLRG1-positive ILC http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
NKp46-positive innate lymphoid cell, human An innate lymphoid cell in the human with the phenotype NKp46-positive that is a precusor for NK cells and ILC3 cells. Synonyms: NKp46-positive ILC http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ILC1, human An ILC1 cell in the human with the phenotype CD56-negative, IL-7Ralpha-positive, T-bet-positive. Synonyms: innate lymphoid cell 1, human http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
group 3 innate lymphoid cell, human A group 3 innate lymphoid cell in the human with the phenotype IL-7Ralpha-positive. Synonyms: ILC3, human http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
NKp44-positive group 3 innate lymphoid cell, human A group 3 innate lymphoid cell in the human with the phenotype IL-7Ralpha-positive, and NKp44-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
NKp44-negative group 3 innate lymphoid cell, human A group 3 innate lymphoid cell in the human with the phenotype IL-7Ralpha-positive, and NKp44-negative. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
group 2 innate lymphoid cell, human A group 2 innate lymphoid cell in the human with the phenotype CD25-positive, CD127-positive, CD161-positive, and GATA-3-positive. Synonyms: ILC2, human http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature innate lymphoid cell An innate lyphoid cell with an immature phenotype. Synonyms: immature ILC http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
effector memory CD4-positive, alpha-beta T cell, terminally differentiated A CD4-positive, alpha beta memory T cell with the phenotype CD45RA-positive, CD45RO-negative, and CCR7-negative. Synonyms: CD4+ TEMRA, CD4-positive TEMRA http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lymphocyte of B lineage, CD19-positive A lymphocyte of B lineage that is CD19-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
B cell, CD19-positive A B cell that is CD19-positive. Synonyms: B lymphocyte, CD19-positive, B-cell, CD19-positive, B-lymphocyte, CD19-positive, CD19+ B cell, CD19-positive B cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD86-positive plasmablast A plasmablast that is CD86-positive. Synonyms: CD86+ plasmablast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD8-positive, alpha-beta memory T cell, CD45RO-positive A CD8-positive, alpha-beta T cell with memory phenotype indicated by being CD45RO and CD127-positive. This cell type is also described as being CD25-negative. Synonyms: CD8-positive, alpha-beta memory T lymphocyte, CD45RO-positive, CD8-positive, alpha-beta memory T-cell, CD45RO-positive, CD8-positive, alpha-beta memory T-lymphocyte, CD45RO-positive http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD4-positive, alpha-beta memory T cell, CD45RO-positive CD4-positive, alpha-beta long-lived T cell with the phenotype CD45RO-positive and CD127-positive. This cell type is also described as being CD25-negative. Synonyms: CD4-positive, alpha-beta memory T lymphocyte, CD45RO-positive, CD4-positive, alpha-beta memory T-cell, CD45RO-positive, CD4-positive, alpha-beta memory T-lymphocyte, CD45RO-positive http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Kit-positive erythroid progenitor cell An erythroid progenitor cell is Kit-positive, Ly6A-negative, CD41-negative, CD127-negative, and CD123-negative. This cell type is also described as being lin-negative, Kit-positive, CD150-negative, CD41-negative, CD105-positive, and FcgR-negative. Synonyms: c- Kit-positive erythroid progenitor cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD34-positive, CD38-positive granulocyte monocyte progenitor A granulocyte monocyte progenitor is CD34-positive, CD38-positive, IL-3receptor-alpha-positive and is CD45RA-negative. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Kit-positive granulocyte monocyte progenitor A granulocyte monocyte progenitor that is Kit-positive, CD34-positive, Fc-gamma receptor II/II-positive, and is Sca-1-negative, Il7ra-negative, Cxc3r1-negative, and CD90-negative. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD34-positive, GlyA-negative erythroid progenitor cell An erythroid progenitor cell that is CD34-positive and is GlyA-negative. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD34-negative, GlyA-negative proerythroblast A proerythoblast that is CD34-negative and GlyA-negative. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell A megakaryocyte erythroid progenitor cell is CD34-positive, CD38-positive and is IL3-receptor alpha-negative and CD45RA-negative. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Kit-positive, CD34-negative megakaryocyte erythroid progenitor cell A megakaryocyte erythroid progenitor cell that is Kit-positive and is Sca1-negative, CD34-negative, CD90-negative, IL7r-alpha-negative and Fcgr II/III-low. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Kit-low, CD34-positive eosinophil progenitor cell A lineage marker-negative, CD34-positive, IL5r-alpha-positive, and Sca1-negative eosinophil progenitor cell. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD34-positive, CD38-positive eosinophil progenitor cell A lineage marker-negative, CD34-positive, CD38-positive, IL3r-alpha-positive, IL5r-alpha-positive, and CD45RA-negative eosinophil progenitor cell. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
macrophage dendritic cell progenitor A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages. Synonyms: MDP http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pre-conventional dendritic cell A lin-negative, MHC-II-negative, CD11c-positive, FLT3-positive cell with intermediate expression of SIRP-alpha. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Kit-positive macrophage dendritic cell progenitor A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages. Marker for this cell is Kit-high, CD115-positive, CD135-positive, Cx3cr1-positive, and is Il7ra-negative. Synonyms: murine MDP http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
GlyA-positive basophilic erythroblast A basophilic erythroblast that is GlyA-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD71-low, GlyA-positive polychromatic erythroblast A polychromatiic erythroblast that is Gly-A-positive and CD71-low. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD71-negative, GlyA-positive orthochromatic erythroblast An erythroblast that is GlyA-positive and CD71-negative. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
GlyA-positive reticulocytes A reticulocyte that is GlyA-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
GlyA-positive erythrocyte An enucleate erythrocyte that is GlyA-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD34-positive, CD41-positive, CD42-positive megakaryocyte progenitor cell A megakaroycotye progenitor cell that is CD34-positive, CD41-positive and CD42-positive on the cell surface. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Kit-positive megakaryocyte progenitor cell A megakaryocyte progenitor cell that is Kit-positive, CD41-positive, CD9-positive, Sca-1-negative, IL7ralpha-negative, CD150-negative, and Fcgamma receptor II/III-low. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD34-positive, CD41-positive, CD42-negative megakaryocyte progenitor cell A megakaryocyte progenitor cell that is CD34-positive, CD41-positive, and CD42-negative. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD34-negative, CD41-positive, CD42-positive megakaryocyte cell A megakaryocyte progenitor cell that is CD34-negative, CD41-positive and CD42-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD9-positive, CD41-positive megakaryocyte cell A megakaryocyte cell with is CD9-positive and CD41-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
basophil mast progenitor cell A cell type that can give rise to basophil and mast cells. This cell is CD34-positive, CD117-positive, CD125-positive, FceRIa-negative, and T1/ST2-negative, and expresses Gata-1, Gata-2, C/EBPa Synonyms: BMCP http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Fc-epsilon RIalpha-low mast cell progenitor A lineage-negative, Kit-positive, CD45-positive mast cell progenitor that is Fc-epsilon RIalpha-low. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Fc-epsilon RIalpha-high basophil progenitor cell A lineage negative, Sca1-negative basophil progenitor cell that is Fc epsilon RIalpha-high. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hematopoietic lineage restricted progenitor cell A hematopoietic progenitor cell that is capable of developing into only one lineage of hematopoietic cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hematopoietic oligopotent progenitor cell A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
short term hematopoietic stem cell A hematopoietic stem cell capable of rapid replenishment of myeloerythroid progenitors and limited self renewal capability. This cell is Kit-positive, Sca1-positive, CD34-positive, CD150-positive, and is Flt3-negative. Synonyms: ST stem cell, ST-HSC http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
long term hematopoietic stem cell A hematopoietic stem cell with long term self renewal capability. This cell is Kit-positive, Sca1-positive, CD150-positive, CD90-low, CD34-negative and Flt3-negative. Synonyms: LT stem cell, LT-HSC http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Slamf1-negative multipotent progenitor cell A hematopoietic progenitor that has restricted self-renewal capability. Cell is Kit-positive, Ly6-positive, CD150-negative and Flt3-negative. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Slamf1-positive multipotent progenitor cell A hematopoietic progenitor that has some limited self-renewal capability. Cells are lin-negative, Kit-positive, CD34-positive, and Slamf1-positive. Synonyms: KSL cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD2-positive, CD5-positive, CD44-positive alpha-beta intraepithelial T cell Intraepithelial T cells with a memory phenotype of CD2-positive, CD5-positive, and CD44-positive. Synonyms: memory alpha beta IEL http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
T follicular helper cell A CD4-positive, CXCR5-positive, CCR7-negative alpha-beta T cell located in follicles of secondary lymph nodes that is BCL6-high, ICOS-high and PD1-high, and stimulates follicular B cells to undergo class-switching and antibody production. Synonyms: T(FH), Tfh http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD34-positive, CD38-negative multipotent progenitor cell A hematopoietic multipotent progenitor cell that is CD34-positive, CD38-negative, CD45RA-negative, and CD90-negative. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Kit-positive, integrin beta7-high basophil mast progenitor cell A basophil mast progenitor cell that is Beta-7 integrin-high, Kit-positive FcRgammaII/III-positive and Sca1-negative. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
early pro-B cell A pro-B cell that is CD22-positive, CD34-positive, CD38-positive and TdT-positive (has TdT activity). Pre-BCR is expressed on the cell surface. Cell is CD19-negative, CD20-negative, complement receptor type 2-negative and CD10-low. D-to-J recombination of the heavy chain occurs at this stage. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
late pro-B cell A pre-B cell precursor is CD19-low, CD22-positive , CD34-positive, CD38-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD38-high pre-BCR positive cell A pre-BCR positive B cell that is CD38-high. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD22-positive, CD38-low small pre-B cell A small pre-B cell that is CD22-positive and CD38-low. Synonyms: small pre-B cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD38-negative immature B cell An immature B cell that is CD38-negative, CD10-low, CD21-low, and CD22-high. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD14-positive, CD16-negative classical monocyte A classical monocyte that is CD14-positive, CD16-negative, CD64-positive, CD163-positive. Synonyms: CD16- monocyte, CD16-negative monocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD8-alpha-positive thymic conventional dendritic cell A conventional thymic dendritic cell that is CD8-alpha-positive. Synonyms: CD8alpha-alpha-positive thymic conventional dendritic cell, DC.8+.Th http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
melanophage A melanin-containing macrophage that obtains the pigment by phagocytosis of melanosomes. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
T-helper 9 cell A T-helper cell that is characterized by secreting interleukin 9 and responding to helminth infections. This cell-type can derives from Th2 cells in the presence of TGF-beta and IL-4. Th2 cytokine production is surpressed. Synonyms: T helper cells type 9, T(H)-9 cell, Th9 http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pulmonary alveolar type 1 cell A squamous pulmonary alveolar epithelial cell that is flattened and branched. A pulmonary alveolar type 1 cell covers more than 98% of the alveolar surface. This large cell has thin (50-100 nm) cytoplasmic extensions to form the air-blood barrier essential for normal gas exchange. Synonyms: lung type 1 cells, membranous pneumocytes, pulmonary alveolar type I cell, small alveolar cells, squamous alveolar cell, squamous alveolar lining cell, type 1 alveolar epithelial cells, type 1 pneumocyte, type I alveolar cells, type I alveolar epithelial cells, type I pneumocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pulmonary alveolar type 2 cell A pulmonary alveolar epithelial cell that modulates the fluid surrounding the alveolar epithelium by secreting and recycling surfactants via specialized organelles called alveolar lamellar bodies. This cell type also contributes to tissue repair and can differentiate after injury into a pulmonary alveolar type 1 cell. This cuboidal cell is thicker than squamous alveolar cells, has a rounded apical surface that projects above the level of the surrounding epithelium, and its free surface is covered by short microvilli. Synonyms: cuboidal type II cell, granular pneumocyte, great alveolar cell, lung type 2 cell, type 2 alveolar epithelial cell, type 2 alveolocyte, type 2 pneumocyte, type II alveolar cell, type II alveolar epithelial cell, type II alveolocyte, type II pneumocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pancreatic acinar cell A secretory cell found in pancreatic acini that secretes digestive enzymes and mucins. This cell is a typical zymogenic cell, have a basal nucleus and basophilic cytoplasm consisting of regular arrays of granular endoplasmic reticulum with mitochondria and dense secretory granules. Synonyms: acinar cell of pancreas http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Feyrter cell A neuroendocrine cell found in the epithelium of the lungs and respiratory tract. This cell type is rounded or elliptical in shape, situated mainly in the basal part of the epithelium; regulates bronchial secretion, smooth muscle contraction, lobular growth, ciliary activity and chemoreception. Cell has an electron-lucent cytoplasm, contains numerous dense-cored vesicles with a clear halo between the core and the limiting membrane. Synonyms: Kultschitzky cell of bronchiole, bronchiolar Kulchitsky cell, respiratory enterochromaffin cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type A enteroendocrine cell An enteroendocrine cell that produces glucagon. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Purkinje myocyte Specialized cardiac myocyte that is subendocardially interspersed with the regular cardiac muscle cell. They are uninucleate cylindrical cells, associated end-to-end in long rows, continue from the node to the atrioventricular bundle; relatively short compared to ordinary myocytes but are nearly twice their diameter. Synonyms: Purkinje cell fiber, Purkinje muscle cell, myocytus conducens cardiacus http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type II vestibular sensory cell Mostly cylindrical, resemble Type 1 in their contents and the presence of a kinocilium and stereocilium apically; much greater variation in size, some almost span the entire thickness of the sensory epithelium, while others are smaller than Type 1; receive multiple efferent nerve boutons around their bases as well as afferent endings, which are small expansions rather than chalices. Synonyms: type 2 vestibular hair cell, type 2 vestibular sensory cell, type II hair cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type I vestibular sensory cell Bottle-shaped with narrow neck; broad, rounded basal portion where nucleus is located; stereocilia and a single kinocilium is present apically; receive nerve bouton at their base from an afferent cup-shaped (chalice or calyx) nerve ending. Synonyms: type 1 vestibular hair cell, type 1 vestibular sensory cell, type I hair cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
enterocyte of epithelium of large intestine A columnar absorptive epithelial cell found in the epithelium of large intestine, specialized for water and electrolyte absorption. Unlike small intestinal enterocytes, those in the large intestine have fewer apical microvilli. Synonyms: columnar cell of the colon, vacuolar absorptive cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
nodal myocyte A specialized cardiac myocyte in the sinoatrial and atrioventricular nodes. The cell is slender and fusiform confined to the nodal center, circumferentially arranged around the nodal artery. Synonyms: P cell, cardiac pacemaker cell, myocytus nodalis http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
transitional myocyte Specialized cardiac myocyte which is in the internodal tract and atrioventricular node. The cell is more slender than ordinary atrial myocytes and has more myofibrils than nodal myocytes. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myocardial endocrine cell The myoendocrine cellis a specialized myocyte localized mainly in the right and left atrial appendages, and also scattered within other areas of the atria and along the conductive system in the ventricular septum. The most conspicuous feature distinguishing myoendocrine cells from other atrial myoctyes is the presence of membane-bounded secretory granules (these granules contain precursor of cardiodilatins or atrial natriuretic polypeptides). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
brush cell of tracheobronchial tree A rare type of columnar epithelial cell that is part of the tracheobronchial epithelium. This cell is characterized by a distinctive tuft of apical microvilli, which extends into the cytoplasm, and a pear-shaped morphology, broad at the base and tapering to a narrow apex. It plays vital roles in chemosensation, producing cytokines like IL-25, and enhancing mucociliary clearance through acetylcholine release to support mucus movement and airway defense. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endo-epithelial cell An epithelial cell derived from endoderm. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ecto-epithelial cell An epithelial cell derived from ectoderm. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
meso-epithelial cell Epithelial cell derived from mesoderm or mesenchyme. Synonyms: epithelial mesenchymal cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pancreatic ductal cell Epithelial cell found in the ducts of the pancreas. This cell type contributes to the high luminal pH. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pancreatic centro-acinar cell A cubodial epithelial cell that is continuous with the lining of intercalated ducts that drain the acinus. This cell type secretes a high pH solution to aid in activation of zymogens, and can differentiate into endocrine and exocrine pancreatic cell types. Synonyms: centroacinar cell of Langerhans, pancreatic centroacinar cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type II cell of carotid body This cell resembles a glia cell, express the glial marker S100 and act as a supporting cell to type I cell. This cell is located in a small cluster of type I and type II cells near the fork of the carotid artery. Synonyms: sheath cell of carotid body http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type II cell of adrenal medulla A chromaffin cell of the adrenal medulla that produces epinephrine. Synonyms: adrenal secreting cell of the adrenal medulla, adrenergic chromaffin cell, epiniphrine secreting cell of the adrenal medulla http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type I cell of adrenal medulla A chromaffin cell of the adrenal medulla that produces norepinephrine. Synonyms: noradrenergic chromaffin cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Boettcher cell A Boettcher cell is a polyhedral cells on the basilar membrane of the cochlea, and is located beneath Claudius cells. A Boettcher cell is considered a supporting cell for the organ of Corti, and is present only in the lower turn of the cochlea. These cells interweave with each other, and project microvilli into the intercellular space. Because of their structural specialization, a Boettcher cell is believed to play a significant role in the function of the cochlea. They demonstrate high levels of calmodulin, and may be involved in mediating Ca(2+) regulation and ion transport. Synonyms: Boettcher's cell, Bottcher cell, Bottcher's cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tanycyte A specialized elongated ventricular ependymal cell with one or more processes that extend into the brain parenchyma or associated blood vessels where they contact blood vessel endothelial cells and/or neurons. These cells are found in the ventricles and circumventricular organs of the brain. They are involved in hormonal regulation, gatekeeping molecules between the bloodstream and cerebrospinal fluid, metabolic sensing, and regulating food intake. Synonyms: stretch cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
specialized cardiac myocyte A cardiac myocyte that is an excitable cells in the myocardium, specifically in the conducting system of heart. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
nongranular leukocyte A leukocyte that lacks granules. Synonyms: agranular leukocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
interstitial cell of Cajal This is a cell found in the gastrointestinal tract of mammals and serves as a pacemaker that triggers gut contraction. ICCs mediate inputs from the enteric nervous system to smooth muscle cells and are thought to be the cells from which gastrointestinal stromal tumors (GISTs) arise. Synonyms: ICC, intestinal pacemaker cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
polar body One of two small cells formed by the first and second meiotic division of oocytes. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
primary polar body A small cell formed by the first meiotic division of oocytes. Synonyms: first polar body, polocytus primarius http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
bone marrow cell A cell found in the bone marrow. This can include fibroblasts, macrophages, adipocytes, osteoblasts, osteoclasts, endothelial cells and hematopoietic cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
secondary polar body A small cell formed by the second meiotic division of oocytes. In mammals, the second polar body may fail to form unless the ovum has been penetrated by a sperm cell. Synonyms: polocytus secundarius, second polar body http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
interstitial cell of ovary A cell that makes up the loose connective tissue of the ovary. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hilus cell of ovary A cell in the hilum of the ovary that produces androgens. Synonyms: hilar cell of ovary http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
internodal tract myocyte A specialised myocyte that lies between the sinoatrial node and the atrioventricular node and is involved in the conduction of electrical signals. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cortical cell of adrenal gland A cell of the adrenal cortex. Cell types include those that synthesize and secrete chemical derivatives (steroids) of cholesterol. Synonyms: adrenal cortex cell, adrenocortical cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
regular cardiac myocyte A cardiac myocyte that is connected to other cardiac myocytes by transverse intercalated discs (GO:0014704) at a regular interval. Synonyms: regular cardiac muscle cell, regular cardiac muscle fiber http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type I cell of adrenal cortex A small, polyhedral, cell found in rounded groups or curved columns with deeply staining nuclei, scanty basophilic cytoplasm and a few lipid droplets. This cell in the zona glomerulosa produces mineralocorticoids. Synonyms: epithelial cell of zona glomerulosa of adrenal gland http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
regular interventricular cardiac myocyte A regular cardiac myocyte of the interventricular region of the heart. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD38-positive naive B cell A CD38-positive naive B cell is a mature B cell that has the phenotype CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, and that has not yet been activated by antigen in the periphery. Synonyms: CD38+ naive B cell, CD38+ naive B lymphocyte, CD38+ naive B-cell, CD38+ naive B-lymphocyte, CD38-positive naive B lymphocyte, CD38-positive naive B-cell, CD38-positive naive B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD38-negative naive B cell A CD38-negative naive B cell is a mature B cell that has the phenotype CD38-negative, surface IgD-positive, surface IgM-positive, and CD27-negative, that has not yet been activated by antigen in the periphery. Synonyms: CD38- naive B cell, CD38- naive B lymphocyte, CD38- naive B-cell, CD38- naive B-lymphocyte, CD38-negative naive B lymphocyte, CD38-negative naive B-cell, CD38-negative naive B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
IgG-positive double negative memory B cell An IgG-positive double negative memory B cell is a double negative memory B cell with the phenotype IgG-positive, IgD-negative, and CD27-negative. Synonyms: IgG+ dn memory B cell, IgG+ dn memory B lymphocyte, IgG+ dn memory B-cell, IgG+ dn memory B-lymphocyte, IgG+ double negative memory B cell, IgG+ double negative memory B lymphocyte, IgG+ double negative memory B-cell, IgG+ double negative memory B-lymphocyte, IgG-positive dn memory B cell, IgG-positive dn memory B lymphocyte, IgG-positive dn memory B-cell, IgG-positive dn memory B-lymphocyte, IgG-positive double negative memory B lymphocyte, IgG-positive double negative memory B-cell, IgG-positive double negative memory B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
IgG-negative double negative memory B cell An IgG-negative double negative memory B cell is a double negative memory B cell with the phenotype IgG-negative, IgD-negative, and CD27-negative. Synonyms: IgG- dn memory B cell, IgG- dn memory B lymphocyte, IgG- dn memory B-cell, IgG- dn memory B-lymphocyte, IgG- double negative memory B cell, IgG- double negative memory B lymphocyte, IgG- double negative memory B-cell, IgG- double negative memory B-lymphocyte, IgG-negative dn memory B cell, IgG-negative dn memory B lymphocyte, IgG-negative dn memory B-cell, IgG-negative dn memory B-lymphocyte, IgG-negative double negative memory B lymphocyte, IgG-negative double negative memory B-cell, IgG-negative double negative memory B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD38-positive IgG memory B cell A CD38-positive IgG memory B cell is a class switched memory B cell that expresses IgG on the cell surface with the phenotype CD38-positive and IgG-positive. Synonyms: CD38+ IgG memory B cell, CD38+ IgG memory B lymphocyte, CD38+ IgG memory B-cell, CD38+ IgG memory B-lymphocyte, CD38-positive IgG memory B lymphocyte, CD38-positive IgG memory B-cell, CD38-positive IgG memory B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
IgD-positive CD38-positive IgG memory B cell An IgD-positive CD38-positive IgG memory B cell is a CD38-positive IgG-positive class switched memory B cell that has class switched and expresses IgD on the cell surface with the phenotype IgD-positive, CD38-positive, and IgG-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
IgD-negative CD38-positive IgG memory B cell An IgD-negative CD38-positive IgG memory B cell is a CD38-positive IgG-positive that has class switched and lacks expression of IgD on the cell surface with the phenotype IgD-negative, CD38-positive, and IgG-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD38-negative IgG memory B cell A CD38-negative IgG memory B cell is a IgG-positive class switched memory B cell that has class switched and expresses IgG on the cell surface with the phenotype CD38-negative, IgD-negative, and IgG-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
B220-positive CD38-positive naive B cell A B220-positive CD38-positive naive B cell is a CD38-positive naive B cell that has the phenotype B220-positive, CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, and that has not yet been activated by antigen in the periphery. Synonyms: B220+CD38+ naive B cell, B220+CD38+ naive B lymphocyte, B220+CD38+ naive B-cell, B220+CD38+ naive B-lymphocyte, B220-positive CD38-positive naive B lymphocyte, B220-positive CD38-positive naive B-cell, B220-positive CD38-positive naive B-lymphocyte, CD38+B220+ naive B cell, CD38+B220+ naive B lymphocyte, CD38+B220+ naive B-cell, CD38+B220+ naive B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
B220-low CD38-positive naive B cell A B220-low CD38-positive naive B cell is a CD38-positive naive B cell that has the phenotype B220-low, CD38-positive, surface IgD-positive, surface IgM-positive, and CD27-negative, that has not yet been activated by antigen in the periphery. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD38-negative unswitched memory B cell An CD38-negative unswitched memory B cell is an unswitched memory B cell that has the phenotype CD38-negative, IgD-positive, CD138-negative, and IgG-negative. Synonyms: CD38- unswitched memory B cell, CD38- unswitched memory B lymphocyte, CD38- unswitched memory B-cell, CD38- unswitched memory B-lymphocyte, CD38-negative unswitched memory B lymphocyte, CD38-negative unswitched memory B-cell, CD38-negative unswitched memory B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
B220-positive CD38-negative unswitched memory B cell A B220-positive CD38-negative unswitched memory B cell is a CD38-negative unswitched memory B cell that has the phenotype B220-positive, CD38-negative, IgD-positive, CD138-negative, and IgG-negative. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
B220-low CD38-negative unswitched memory B cell A B220-low CD38-negative unswitched memory B cell is a CD38-negative unswitched memory B cell that has the phenotype B220-low, CD38-negative, IgD-positive, CD138-negative, and IgG-negative. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD38-positive unswitched memory B cell A CD38-positive unswitched memory B cell is an unswitched memory B cell that has the phenotype CD38-positive, IgD-positive, CD138-negative, and IgG-negative. Synonyms: CD38+ unswitched memory B cell, CD38+ unswitched memory B lymphocyte, CD38+ unswitched memory B-cell, CD38+ unswitched memory B-lymphocyte, CD38-positive unswitched memory B lymphocyte, CD38-positive unswitched memory B-cell, CD38-positive unswitched memory B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
B220-positive CD38-positive unswitched memory B cell A B220-positive CD38-positive unswitched memory B cell is a CD38-positive unswitched memory B cell that has the phenotype B220-positive, CD38-positive, IgD-positive, CD138-negative, and IgG-negative. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
B220-low CD38-positive unswitched memory B cell A B220-low CD38-positive unswitched memory B cell is a CD38-positive unswitched memory B cell that has the phenotype B220-low, CD38-positive, IgD-positive, CD138-negative, and IgG-negative. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
IgG-negative class switched memory B cell A class switched memory B cell that lacks IgG on the cell surface. Synonyms: IgG- class switched memory B cell, IgG- class switched memory B lymphocyte, IgG- class switched memory B-cell, IgG- class switched memory B-lymphocyte, IgG-negative class switched memory B lymphocyte, IgG-negative class switched memory B-cell, IgG-negative class switched memory B-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD38-negative IgG-negative class switched memory B cell A CD38-negative IgG-negative memory B cell is a IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD38-negative and IgG-negative. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD38-positive IgG-negative class switched memory B cell A CD38-positive IgG-negative memory B cell is an IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD38-positive and IgG-negative. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD24-positive CD38-negative IgG-negative class switched memory B cell An CD24-positive CD38-negative IgG-negative memory B cell is a CD38-negative IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD24-positive, CD38-negative, and IgG-negative. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD24-negative CD38-negative IgG-negative class switched memory B cell A CD24-negative CD38-negative IgG-negative memory B cell is a CD38-negative IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype CD24-negative, CD38-negative, and IgG-negative. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
B220-positive CD38-positive IgG-negative class switched memory B cell A B220-positive CD38-positive IgG-negative memory B cell is a CD38-positive IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype B220-positive, CD38-positive, and IgG-negative. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
B220-low CD38-positive IgG-negative class switched memory B cell A B220-low CD38-positive IgG-negative memory B cell is a CD38-positive IgG-negative class switched memory B cell that lacks IgG on the cell surface with the phenotype B220-low, CD38-positive, and IgG-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD27-positive gamma-delta T cell A circulating gamma-delta T cell that is CD27-positive and capable of producing IFN-gamma. Synonyms: gammadelta27-positive, gd27-positive http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD27-negative gamma-delta T cell A circulating gamma-delta T cell that expresses RORgamma(t), is CD27-negative and is capable of IL-17 secretion. Synonyms: gammadelta-17 cells http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD25-positive, CD27-positive immature gamma-delta T cell A CD25-positive, CD27-positive immature gamma-delta T cell found in the thymus that has an immature phenotype (i.e. CD24-high, CD25-high, CD62L-high, CD44-high, CD2-low, CD5-low). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
innate effector T cell A T cell with a receptor of limited diversity that is capable of immediate effector functions upon stimulation. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Tc17 cell A CD8-positive, alpha-beta T cell that has the phenotype CXCR3-negative, CCR6-positive, CCR5-high, CD45RA-negative, and capable of producing IL-17 and some IFNg. Synonyms: CD8-positive Th17 cell, Tc17 CD8+ T cell, Tc17 T cell, Tc17 T lymphocyte, Tc17 T-cell, Tc17 T-lymphocyte, Th17 CD8-positive T cell, Th17 non-TFH CD8-positive T cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
regular atrial cardiac myocyte Regular cardiac myocyte of a cardiac atrium. Synonyms: atrial cardiac muscle cell, atrial myocyte, regular atrial cardiac muscle fiber, regular cardiac muscle cell of atrium http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
regular interatrial cardiac myocyte A cardiac myocyte of the interatrial region of the heart. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
regular ventricular cardiac myocyte Regular cardiac myocyte of a cardiac ventricle. Synonyms: regular cardiac muscle cell of ventricle, regular ventricular cardiac muscle fiber, ventricular myocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stromal cell of ovary A stomal cell of the ovary Synonyms: ovarian stromal cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stromal cell of ovarian cortex A stromal cell of the ovarian cortex. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stromal cell of ovarian medulla A stromal cell of the ovarian medulla. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
nonkeratinized cell of epidermis Epidermal cells that do not contain keratin. Cell type is usually associated with moist epidermal tissues. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type II cell of adrenal cortex A cell in the zona fasciculata that produce glucocorticoids, e.g cortisol. Synonyms: type II cortical cell of adrenal gland http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type III cell of adrenal cortex A cell in the zona reticularis that produce sex hormones. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endothelial cell of lymphatic vessel A endothelial cell of a lymphatic vessel. The border of the oak leaf-shaped endothelial cell of initial lymphatics are joined by specialized buttons. The discontinuous feature of buttons distinguishes them from zippers in collecting lymphatics, but both types of junctions are composed of proteins typical of adherens junctions and tight junctions found in the endothelium of blood vessels. Buttons seal the sides of flaps of the oak leaf-shaped endothelial cell, leaving open the tips of flaps as routes for fluid entry without disassembly and reformation of intercellular junctions. Synonyms: LEC, lymphatic endothelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endothelial cell of vascular tree An endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels. Synonyms: vascular endothelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
skin sebocyte An acinar cell that is part of a skin sebaceous gland. This cell produces and secretes sebum into hair follicles. Synonyms: acinar cell of skin sebaceous gland http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
active chief cell of parathyroid gland A parathyroid chief cell that is actively secreting hormone. Have large Golgi complexes with numerous vesicles and small membrane-bound granules; secretory granules are rare, cytoplasmic glycogen sparse, much of the cytoplasm being occupied by flat sacs of granular endoplasmic reticulum in parallel arrays; in normal humans, inactive chief cells outnumber active chief cells in a ratio of 3-5:1 http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
dark cell of eccrine sweat gland A cell pyramidal in shape, with their broad ends facing and forming the greater extent of the lining of the main lumen. Secretes glycoproteins associated with mucus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
dark chief cell of parathyroid gland A chief cell that is smaller than light chief cells and has a smaller and darker nucleus and a finely granular cytoplasm with many granules. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
capillary endothelial cell An endothelial cell found in capillaries. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
multiciliated columnar cell of tracheobronchial tree A multi-ciliated epithelial cell located in the trachea and bronchi, characterized by a columnar shape and motile cilia on its apical surface. These cilia facilitate mucociliary clearance by moving mucus and trapped particles toward the pharynx. Synonyms: ciliated columnar cell of tracheobronchial tree http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
clear cell of eccrine sweat gland A sweat producing cell of eccrine sweat glands. Pyramidal in shape, with its base resting on the basal lamina or myoepitheliocytes, and its microvillus-covered apical plasma membrane line up the intercellular canaliculi. Cell is not stained by hematoxylin or eosin. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
clear chief cell of parathyroid gland A chief cell of parathyroid glands that does not stain with hematoxylin or eosin. This cell is larger, has a larger nucleus and fewer secretory granules than dark chief cells. Synonyms: clear chief cell of parathyroid cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
dental pulp cell A cell found within the dental pulp. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of uterus An epithelial cell of the uterus. This cell has a mesodermal origin. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelioid macrophage Epithelioid macrophage is an activated macrophage that resembles an epithelial cell with finely granular, pale eosinophilic cytoplasm and central, ovoid nucleus (oval or elongate). This cell type is able to merge into one another to form aggregates. The presence of such aggregates may characterize some pathologic conditions, mainly granulomatous inflammation. Synonyms: epithelioid histocyte, epitheloid macrophage http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
late promyelocyte A promyelocyte that is considerably smaller, with more condensed chromatin, and nucleoli are no longer conspicuous. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
columnar cell of endocervix A simple columnar epithelial cell located in the endocervix. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
corneocyte The dead keratin-filled squamous cell of the stratum corneum. This cell type lacks a nucleus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
early promyelocyte A promyelocyte with a nucleus that is indented and contains more marginated heterochromatin compared to its precursor cell (myeloblast); cytoplasm is deeply basophilic and contains numerous mitochondria and meandering cysternae of endoplasmic reticulum; largest of the granulocyte lineages. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
echinocyte A crenated erythrocyte with 30+ crenations, bumps or spurs that are the result of damage due to age or disease. Synonyms: burr cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endosteal cell A cell type that makes up the highly vascular membrane lining the marrow cavity of long bones. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
external epithelial cell of tympanic membrane Epithelial cell found on the external side of the tympanic membrane http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
general ecto-epithelial cell Epithelial cells derived from general body ectoderm and ectoderm placodes. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
basal external epithelial cell of tympanic membrane A cell type found in the basal epithelial layer on the external side of the tympanic membrane. Cell type is flattened with intracellular spaces of variable dimensions. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
superficial external epithelial cell of tympanic membrane A cell type found on the superficial layer of the external side of the tympanic membrane. This cell-type lacks a nucleus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
internal epithelial cell of tympanic membrane An extremely flattened cell type found on the inner side of the tympanic membrane. The surface of this cell type carries sparse pleomorphic microvilli that are more common near the junctional zones. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
internal pillar cell of cochlea A rod-shpaed cell that forms a single row adjacent to and supporting the inner hair cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
external pillar cell of cochlea A rod-shaped cell found in 3 or 4 rows that lie adjacent to and support the outer hair cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
phalangeal cell A supporting cell that is attached to the basement membrane and forms rows that support the hair cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of Malassez An epithelial cell that remains from the disintegration of the epithelial root sheath involved in the development of teeth. Synonyms: epithelial cell rests of Malassez, epithelial debris of Malassez http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
olfactory epithelial cell A specialized cell involved in sensory perception of smell. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
border cell of cochlea A border cell is a slender columnar cell on the medial portion of the basilar membrane. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
basal cell of olfactory epithelium An epithelial cell located on the basal lamina of the olfactory epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
keratinized cell of the oral mucosa A keratinized cell located in the hard palate or gingiva. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
globose cell of olfactory epithelium A rounded or elliptical epithelial cell, with pale-staining open face nucleus and pale cytoplasm rich in free ribosomes and clusters of centrioles; form a distinct basal zone spaced slightly from the basal surface of the epithelium. Synonyms: blastema cell of olfactory epithelium http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
interdental cell of cochlea A long, spindle-shaped supporting cells arranged in parallel rows that secretes components of the tectorial membrane and potassium ions into the endolymph. Synonyms: interdental cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
extraglomerular mesangial cell A cell that is a specialized type of pericyte providing structural support for the capillary loops of kidney. A flat, elongated cell with extensive fine cytoplasmic processes found outside the kidney glomerulus near the macula densa and bound laterally by afferent and efferent arterioles. Being phagocytic, this cell participates in the continuous turnover of the basal lamina by removing its outer portion containing residues of filtration, while the lamina is renewed on its inner surface by the endothelial cells. Synonyms: Goormaghtigh cell, polar cushion cells http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
follicular cell of ovary A cell within the follicle of an ovary. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
primary follicular cell of ovary A cell within the primary follicle of the ovary. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
secondary follicular cell of ovary A cell of a secondary follicile within the ovary. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
folliculostellate cell of pars distalis of adenohypophysis A supporting cell of the anterior pituitary gland involved in trophic and catabolic processes; expresses a broad spectrum of cytokeratins indicative of their epithelial nature. Synonyms: folliculostellate cell of pars anterior of adenohypophysis http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of stomach An epithelial cell found in the lining of the stomach. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
foveolar cell of stomach A simple columnar cell that populates the entire luminal surface including the gastric pits. This cell types secrete mucus to form a thick protective, lubricant layer over the gastric wall. Synonyms: surface mucosal cell of stomach http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mucous cell of stomach An epithelial cell of the stomach. This cell produces mucous. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mucous neck cell of gastric gland A columnar epithelial mucous secreting cell located in the neck of the gastric glands. These cells have numerous apical secretory vesicles containing mucins and a basally displaced nucleus. The mucous they secrete is distinct histochemically from that of the surface mucous cells of stomach. Synonyms: mucous neck cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stem cell of gastric gland A stomach epithelial cell that is olumnar in form with a few short apical microvilli; relatively undifferentiated mitotic cell from which other types of gland are derived; few in number, situated in the isthmus region of the gland and base of the gastric pit. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
basal proper cell of olfactory epithelium A flat or angular epithelial cell with condensed nuclei and darkly staining cytoplasm containing numerous intermediate filaments inserted into desmosomes contacting surrounding supporting cells; lie in contact with the basal lamina of olfactory epithelium. Synonyms: horizontal basal cells http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
basal cell of epidermis A mitotically active, columnar-shaped keratinocyte located in the stratum basale of the epidermis and attached to the basement membrane. This cell exhibits heterogeneity, encompassing stem and progenitor subpopulations with distinct molecular and proliferative characteristics (Haensel et al., 2020), and serves as the primary source of new keratinocytes for epidermal renewal, homeostasis, and regeneration. Synonyms: epidermal basal cell, epidermal basal keratinocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
glomerular endothelial cell An endothelial cell that is part of the glomerulus of the kidney. This cell is flattened, highly fenestrated, and plays a vital role in the formation of glomerular ultrafiltrate. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
granular cell of epidermis A keratinocyte located in the stratum granulosum of the epidermis, characterized by the presence of keratohyalin granules containing filaggrin—which aggregate keratin filament —and by lamellar granules that secrete lipids and enzymes essential for forming the skin’s waterproof barrier. As these cells progress toward the surface, they adopt a flattened morphology and initiate keratinization to become corneocyte and form the protective stratum corneum. In human epidermis, granular keratinocytes are transcriptomically distinguished by high expression of differentiation markers such as DSC1, KRT2, IVL, and TGM3 (Wang et al., 2020), and LOR, FLG, and SPINK5 (Cheng et al., 2018). Synonyms: granular keratinocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
squamous cell of epidermis A flat keratinocyte immediately below the cornified layer. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
granulocytopoietic cell A cell involved in the formation of a granulocyte. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
metamyelocyte A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a myelocyte and a band form cell. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myelocyte A cell type that is the first of the maturation stages of the granulocytic leukocytes normally found in the bone marrow. Granules are seen in the cytoplasm. The nuclear material of the myelocyte is denser than that of the myeloblast but lacks a definable membrane. The cell is flat and contains increasing numbers of granules as maturation progresses. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
monopoietic cell A cell involved in the formation of a monocyte (monopoiesis). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hepatic stem cell A stem cell that can give rise to the cells of the liver. The term usually refers to the self-renewing pool of hepatocyte precursors in the adult liver (differently from 'hepatoblast', often used for fetal precursors of hepatocytes). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hepatic oval stem cell A transient hepatic stem cell observed after liver injury with a high nuclear to cytoplasm ratio that can differentiate into mature hepatocytes and bile duct cells. Arises from more than one tissue. Synonyms: hepatic oval cell, hepatic progenitor cell, liver progenitor cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
inactive chief cell of parathyoid gland A parathyroid chief cell that is not actively secreting hormone. Contains small Golgi complexes with only a few grouped vesicles and membrane-bound secretory granules; glycogen and many lipofuscin granules abound but sacs of granular endoplasmic reticulum are rare and dispersed. In normal humans, inactive chief cells out number active chief cells in a ratio of 3-5:1. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
oncocyte A large epithelial cell with an extremely acidophilic and granular cytoplasm, containing vast numbers of mitochondria; such cells may undergo neoplastic transformation. From the Greek word onkos meaning swelling, this cell type is found in parathyroid, salivary and thyroid glands. Synonyms: oxyphil http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
oxyphil cell of parathyroid gland An oncocyte located in the parathyroid gland. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
oxyphil cell of thyroid An oncocyte located in the thyroid. Synonyms: Askanazy cells, Hurthle cells http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
renal beta-intercalated cell A renal intercalated cell that secretes base and reabsorbs acid in the distal segments of the kidney tubule to maintain acid/base balance. Synonyms: type B intercalated cell, type B-IC http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of tracheobronchial tree An epithelial cell of the tracheobronchial tree. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tuft cell of large intestine A tuft cell that is part of the epithelium of large intestine. Synonyms: brush cell of epithelium proper of large intestine, brush cell of large intestine, tuft cell of epithelium of large intestine http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tuft cell An epithelial cell found in various organs, including the gastrointestinal and respiratory tracts, characterized by a tuft of 120-140 blunt microvilli on its apical surface. This cell exhibits diverse functions depending on its location, which includes chemosensation, initiation of immune responses, contribution to mucociliary clearance, and defense against parasites. Synonyms: brush cell, caveolated cell, fibrillovesicular cell, multivesicular cell, peculiar cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
brush cell of lobular bronchiole A brush cell found in the epithelium of lobular bronchiole. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
brush cell of terminal bronchiole A brush cell of the epithelium in the terminal bronchiole. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
brush cell of trachea Brush cell of the epithelium in the trachea. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
brush cell of bronchus A brush cell found in the epithelium of bronchus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
intermediate epitheliocyte An epithelial cell present in the trachea and bronchi; columnar in shape; generally lack cilia; immature forms of ciliated or secretory cells which have been formed from stem cells. Synonyms: undifferentiated columnar cell of tracheobronchial tree http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
red muscle cell A slow muscle cell that contains high levels of myoglobin and oxygen storing proteins giving the cell a red appearance. Synonyms: oxidative muscle fiber, red muscle fiber http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type I muscle cell A slow muscle cell that has large amounts of myoglobin, stores energy as triglycerides, generates ATP by the oxidative method and is resistant to fatigue. Synonyms: slow twitch fiber, slow twitch muscle cell, slow twitch muscle fiber, slow-twitch muscle fiber, type 1 muscle cell, type 1 muscle fiber, type I muscle fiber http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type II muscle cell A fast muscle fiber cell that stores energy in the form of glycogen and creatine phosphate. Synonyms: type 2 muscle cell, type 2 muscle fiber, type II muscle fiber http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
white muscle cell A muscle cell with low content of myoglobin and other oxygen storing proteins. This muscle cell has a white appearance. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type IIa muscle cell A type II muscle cell that contains large amounts of myoglobin, has many mitochondria and very many blood capillaries. Type II A cells are red, have a very high capacity for generating ATP by oxidative metabolic processes, split ATP at a very rapid rate, have a fast contraction velocity and are resistant to fatigue. Synonyms: fast twitch A, fatigue resistant fast twitch muscle cell, type 2a muscle cell, type 2a muscle fiber, type IIa muscle fiber http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type IIb muscle cell A type II muscle cell that contains a low content of myoglobin, relatively few mitochondria, relatively few blood capillaries and large amounts of glycogen. Type II B fibres are white, geared to generate ATP by anaerobic metabolic processes, not able to supply skeletal muscle fibres continuously with sufficient ATP, fatigue easily, split ATP at a fast rate and have a fast contraction velocity. Synonyms: type 2b muscle cell, type 2b muscle fiber, type IIb muscle fiber http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
intermediate muscle cell An intermediate muscle cell that has characteristics of both fast and slow muscle cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
intermediate trophoblast cell A trophoblast that leaves the placenta and invades the endometrium and myometrium. This cell type is crucial in increasing blood flow to the fetus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature dendritic epithelial T cell precursor A double negative thymocyte that has a T cell receptor consisting of a gamma chain that has as part a Vgamma3 segment, and a delta chain. This cell type is CD4-negative, CD8-negative and CD24-positive. This cell-type is found in the fetal thymus with highest numbers occurring at E17-E18. Synonyms: immature DEC precursor, immature DETC precursor http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
anchoring trophoblast A trophoblast found at the junction of the placenta. This cell type makes a unique fibronectin-trophouteronectin junction that helps mediate attachment of the placenta to the uterus. This cell type is also found junction of the chorion layer of the external membranes and the decidua. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
interstitial cell of pineal gland A cell located between the pinealocytes. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
keratinized squamous cell of esophagus A squamous cell that has keratin in the esophagus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
vertebrate lens cell A cell comprising the transparent, biconvex body separating the posterior chamber and vitreous body, and constituting part of the refracting mechanism of the mammalian eye. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
anterior lens cell A cell of the transparent layer of simple cuboidal epithelium over the anterior surface of the lens; transform into lens fiber(s). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lens epithelial cell A cell of the cuboidal epithelium that covers the lens. The cells of the lens epithelium regulate most of the homeostatic functions of the lens. As ions, nutrients, and liquid enter the lens from the aqueous humor, Na+/K+ ATPase pumps in the lens epithelial cells pump ions out of the lens to maintain appropriate lens osmolarity and volume, with equatorially positioned lens epithelium cells contributing most to this current. The activity of the Na+/K+ ATPases keeps water and current flowing through the lens from the poles and exiting through the equatorial regions. The cells of the lens epithelium also serve as the progenitors for new lens fibers. It constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
secondary lens fiber A lens fiber cell that develops from primary lens fiber; located towards the center of lens; cell organelles are normally degraded or in the process of being degraded. Synonyms: secondary lens fibre http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
non-nucleated secondary lens fiber A secondary lens fiber cell that lacks a nucleus. Synonyms: non-nucleated secondary lens fibre http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
nucleated secondary lens fiber A secondary fiber cell that contains a nucleus. Synonyms: nucleated secondary lens fibre http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
primary lens fiber An elongating cell that rapidly obliterates the lumen of the lens vesicle. Subsequently, differentiation of this cell type at the lens equator leads to the formation of secondary fiber cells that come to overlie the primary fibers. Synonyms: primary lens fibre http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
light chief cell of parathyroid gland A chief cell that is bigger than dark chief cells and has a larger and lighter nucleus and a cytoplasm with few granules. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of prostate An epithelial cell of the prostate. Synonyms: prostate epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of prostatic duct An epithelial cell of prostatic duct. Synonyms: ductal epithelial cell of prostate http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of prostatic acinus An epithelial cell of the prostatic acinus. Synonyms: acinar epithelial cell of prostate http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
basal cell of prostatic acinus A cell of the basal layer of the epithelium in the prostatic acinus. Synonyms: basal epithelial cell of prostatic acinus http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
luminal cell of prostatic acinus A cell of the luminal layer of the epithelium in the prostatic acinus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
basal epithelial cell of prostatic duct A cell that constitutes the basal layer of epithelium in the prostatic duct. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
luminal epithelial cell of prostatic duct A cell that constitutes the luminal layer of epithelium of prostatic duct. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
marrow fibroblast A fibroblast in the bone marrow. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pulmonary interstitial fibroblast A fibroblasts found in interstitial spaces in the pulmonary tract. Greater numbers of these cells are found in idiopathic pulmonary fibrosis. Synonyms: pulmonary myofibroblast, pulmonary septal cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
nucleate cell A cell containing at least one nucleus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle cell of sphincter of pupil A circular smooth muscle cell of the iris, innervated by the ciliary nerves (parasympathetic), and acting to contract the pupil. This muscle cell derives from neuroectoderm. This smooth muscle cell results from transformation of epithelial cells to smooth muscle cells. Synonyms: smooth muscle fiber of sphincter of pupil http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
squamous cell of ectocervix A stratified squamous epithelial cell located in the ectocervix. Synonyms: ectocervical squamous cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
peripheral blood stem cell A hematopoeitic stem cell found in the blood. Normally found in very limited numbers in the peripheral circulation (less than 0.1% of all nucleated cells). Synonyms: PBSC http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pleural macrophage A tissue macrophage that is in the pleural space. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pluripotent stem cell A pluripotent stem cell has the ability to form cells from all three germ layers (ectoderm, mesoderm, and endoderm). However, unlike totipotent stem cells, they cell can not generate all the cells of the whole organism such as placenta. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
primitive cardiac myocyte A stem cell that can differentiate into a cardiac myocyte. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
intestinal crypt stem cell A stem cell located in epithelium the based of the crypt of Lieberkuhn. Division of these cells serve both to maintain the stem cell population and produce the transit amplifying cells that are all precursors of all cell types that populate the intestinal epithelium. Synonyms: stem cell of intestinal crypt of Lieberkuhn http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of alimentary canal An epithelial cell of the musculomembranous digestive tube extending from the mouth to the anus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of esophagus An epithelial cell of the lining of the esophagus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of large intestine An epithelial cell of the lining of the large intestine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of small intestine An epithelial cell of the lining of the small intestine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stromal cell of endometrium A stromal cell of the endometrium, characterized by its fibroblast-like morphology, regenerative capacity, and ability to undergo decidualization. It differentiates into a decidual stromal cell during pregnancy, essential for embryo implantation and maintenance. This cell is involved in tissue proliferation, remodeling, and breakdown, responding to hormonal changes, particularly estrogen and progesterone. Synonyms: endometrial stromal cell, endometrial stromal fibroblast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
supporting cell of carotid body A supportive cell that has characteristics of glial cell. Processes of this cell envelope the junctions between glomus cells and nerve endings. Synonyms: carotid body sustentacular cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of thyroid gland An epithelial cell of thyroid gland. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
thyroid follicular cell An epithelial cell that is part of the thyroid follicle epithelium, with a shape that ranges from squamous when inactive to cuboidal or columnar when active, reflecting its hormonal activity. Its apical surface is lined with microvilli projecting into the colloid-filled lumen, where it synthesizes, stores, and secretes the thyroid hormones thyroxine (T4) and triiodothyronine (T3), releasing them into the bloodstream in response to thyroid-stimulating hormone (TSH). Synonyms: follicular cell of thyroid gland, principal cell of thyroid gland, thyroid gland follicular cell, thyroid hormone secreting cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of parathyroid gland An epithelial cell of the parathyroid gland. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endothelial cell of viscerocranial mucosa An endothelial cell found in the mucosa associated with the facial skeleton. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endothelial cell of sinusoid An endothelial cell that lines any of the venous cavities through which blood passes in various glands and organs such as the spleen and liver. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
transitional cell of parathyroid gland One of three types of epithelial cells that populate the parathyroid gland; cytological characteristics intermediate between those of the chief cell and of the oxyphil cell. Because only one hormone is produced, the three cell forms are widely believed to be different phases in the life cycle of a single cell type, with the chief cell being its physiologically active stage. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type A cell of stomach A type of enteroendocrine cell found in the stomach that secretes glucagon. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type D cell of colon A D cell located in the colon. Synonyms: colon D-cell, colonic delta cell, delta cell of colon http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type D cell of small intestine A type D cell of the small intestine. Synonyms: delta cell of small intestine, small intestine D-cell, small intestine delta cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type D cell of stomach A type D cell found in the stomach. Synonyms: delta cell of stomach, stomach D-cell, stomach delta cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
P/D1 enteroendocrine cell An enteroendocrine cell that stores and secretes Ghrelin. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
vasoactive intestinal peptide secreting cell An endocrine cell that secretes vasoactive intestinal peptide. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type EC2 enteroendocrine cell A type EC enteroendocrine cell in the duodenum and jejunum that stores and secretes motilin and 5-hydroxytryptamine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type EC1 enteroendocrine cell A type EC enteredocrine cell in the intestines that stores and secretes substance P and 5-hydroxytryptamine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
motilin secreting cell A cell that secretes motilin, a gastric hormone that at low pH inhibits gastric motor activity, whereas at high pH has a stimulating effect. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type ECL enteroendocrine cell A type EC enteroendocrine cell type that is numerous in the fundus of the stomach; stores 5-hydroxytryptamine and histamine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
histamine secreting cell A cell type that secretes histamine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type I enteroendocrine cell An enteroendocrine cell commonest in the duodenum and jejunum, rare in ileum, that secretes cholecystokinin. This cell type is involved in the regulation of digestive enzymes and bile. Synonyms: CCK cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
GIP cell An enteroendocrine cell of duodenum and jejunum that produces gastric inhibitory peptide. Synonyms: type K enteroendocrine cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type L enteroendocrine cell A enteroendocrine cell type that is numerous in ileum, present in jejunum and large intestine, few in duodenum. This cell type produces glucagon-like immunoreactants (glicentin, glucagon-37, glucagon-29, GLP-1 and -2) and PYY. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type N enteroendocrine cell An enteroendocrine cell found in the ileum and jejunum that produces neurotensin. Synonyms: N cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type S enteroendocrine cell Scattered in duodenojejunal mucosa, this enteroendocrine cell secretes secretin and serotonin. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type TG enteroendocrine cell An enteroendocrine cell which produces a gastrin- and cholecystokinin-like peptide. The apical microvilli-rich plasma membrane is in open contact with the small intestine mucosa. This cell type is devoid of gastrin-17 but contains other fragments of the gastrin polypeptide. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ecto-epithelial cell of viscerocranial mucosa An epithelial cell of the mucosa associated with facial skeleton. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type X enteroendocrine cell An enteroendocrine cell found in the fundus and pylorus; this cell type has dense round secretory granules that contain ghrelin. Synonyms: A-like, X/A-like http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type III taste bud cell A taste receptor cell that is characterized by morphologically identifiable synaptic contacts with the gustatory nerve fibers and expression of the synaptic membrane protein-25 (SNAP-25) and NCAM. Synonyms: type 3 taste cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type II taste cell A taste receptor cell that has a short microvilli, a projecting apical region, a large rounded nucleus, and expresses taste chemoreceptors thus making them the transducing cell for taste qualities. Synonyms: type 2 taste cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type IV taste receptor cell A rounded, mitotically active stem cell which is the source of new cells of the taste bud; located basally. Synonyms: type 4 taste cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type V taste receptor cell A cell type that forms the boundary with the surrounding epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type I taste bud cell A densely staining taste receptor cell that contains many dense vacuoles in their apical regions which project into the apical space and bear microvilli. This cell type serves as a supporting cell by surrounding and isolating the other cell types from each other; secrete a dense amorphous material that surrounds the microvilli in the taste pore. This cell type expresses a glial glutumate transporter, GLAST. Synonyms: dark tongue cell, type I taste cell, type taste 1 cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Y chromosome-bearing sperm cell A sperm bearing a Y chromosome. Chromosomal and genetic sex is established at fertilization in mammals and depends upon whether an X-bearing sperm or a Y-bearing sperm fertilizes the X-bearing ovum. Synonyms: Y bearing sperm, Y-bearing sperm http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
X chromosome-bearing sperm cell A sperm bearing an X chromosome. Chromosomal and genetic sex is established at fertilization in mammals and depends upon whether an X-bearing sperm or a Y-bearing sperm fertilizes the X-bearing ovum. Synonyms: X bearing sperm, X-bearing sperm http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type I cell of carotid body A round or oval neuroepithelial cell that contacts other type I cells or capillaries. They occur in clusters that are surrounded by sheath cells (type-II cells) in the carotid body. This cell type is capable of secreting a number of neurotransmitters. Synonyms: glomus cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of thymus An epithelial cell of the thymus. Epithelial reticular cells are pleomorphic, stellate, non-phagocytic cells which seem to be supportive in function and are held together by desmosomes. They replace the fibroblastoid reticular cells found in other lymphoid organs. Other epithelial cells in the medulla have the ultrastructure of secretory cells. Although different epithelial cells throughout the thymus appear alike by light microscopy their ultrastructure and function varies. Synonyms: epithelial cell of thymus gland, epithelial reticular cell, epithelial reticular cell of thymus, thymic epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type-1 epithelial cell of thymus An epithelial cell with a well defined Golgi apparatus that makes up the continuous layer of cells bordering the thymic tissue beneath the capsule. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type-6 epithelial cell of thymus A thymic epithelial cell that has an eccentric, round, or irregularly shaped hetero or euchromatic nucleus. The hallmark of this cell type is the presence of vacuoles, which are clustered in one area of the cytoplasm in the vicinity of the nucleus. The vacuoles are small and acquire a grape-like form, occasionally showing delicate internal microvillous projections. Synonyms: cystic thymic epithelial cells, large mTEC, large medullary thymic epithelial cells http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type-4 epithelial cell of thymus An epithelial cell with high nuclear and cytoplasmic electron-density. This cell type is found in the deeper portions of the cortex but is more abundant in the medulla of the thymus. Synonyms: dark thymic epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type-3 epithelial cell of thymus A thymic epithelial cell with moderate nuclear and cytoplasmic electron-density. Scattered in the cortex, this cell type is predominant in the mid and deep cortex. Synonyms: intermediate thymic epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type-5 epithelial cell of thymus A thymic epithelial cell type with low nuclear and cytoplasmic electrondensity; has a round, euchromatic nucleus and occurs in small groups at the corticomedullary junction or scattered singly in the medulla. Synonyms: undifferentiated mTEC, undifferentiated medullary thymic epithelial cell, undifferentiated thymic epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type-2 epithelial cell of thymus An epithelial cell scattered in the cortex, predominant in the outer cortex with a large pale nucleus and a prominent nucleolus. Synonyms: pale thymic epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type-7 epithelial cell of thymus A small medullary thymic epithelial cell with a spindle shape, often arranged in groups and connected to each other by large desmosomes and interdigitations. The cytoplasm is sparse, with scanty organelles and thick bundles of cytokeratin. Synonyms: spindle shaped mTEC, spindle shaped medullary thymic epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type B synovial cell A resident stromal cell located in the synovial membrane and responsible for the production of immune-related cytokines and chemokines. This cell type secretes glycoproteins and hyaluronic acid, has abundant granular endoplasmic reticulum, but contains fewer vacuoles and vesicles. Synonyms: fibroblast-like synoviocyte, synovial fibroblast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type A synovial cell A synovial cell that is macrophage-like, characterized by surface ruffles or lamellipodia, plasma membrane invaginations and associated micropinocytotic vesicles, Golgi apparatus and little granular endoplasmic reticulum. Synonyms: type A synoviocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pigmented ciliary epithelial cell A cell that is part of pigmented ciliary epithelium. This cell type uptakes sodium and chloride ions from stromal interstitium and passes the ions to non-pigmented ciliary epithelial cells via gap junctions. Synonyms: PE cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
non-pigmented ciliary epithelial cell A cell that is part of non-pigmented ciliary epithelium. This cell type participates in aqueous humor formation by releasing solute, principally sodium and chloride ions received from pigmented epithelial cells via gap junctions, into the aqueous humor of the eye. Synonyms: NPE cell, nonpigmented ciliary epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of distal tubule An epithelial cell of the distal convoluted tubule of the kidney that helps regulate systemic levels of potassium, sodium, calcium, and pH. Synonyms: kidney distal tubule epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of proximal tubule An epithelial cell of the proximal tubule of the kidney. Synonyms: kidney proximal tubule epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
brush border cell of the proximal tubule A brush border epithelial cell located in the proximal tubule of the kidney, essential for reabsorbing substances like glucose and amino acids from the glomerular filtrate. These cells also secrete organic ions, playing a crucial role in maintaining kidney homeostasis, including electrolyte and acid-base balance, and excreting metabolic waste. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of skin gland An epithelial cell of a skin gland. Synonyms: epithelial cell of gland of skin http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
corticotroph A basophil chromphil cell of the anterior pitiutary gland that produce adrenocorticotropic hormone, melanocyte-stimulating hormone and lipotropin. This cell type is irregular in shape and has short dendritic processes which are inserted among other neighboring cells; http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mammosomatotroph An acidophil cell of the anterior pituitary gland that produces both prolactin and growth hormone. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mammotroph An acidophilic cell of the anterior pituitary that produces prolactin. Synonyms: epsilon-acidophil, lactotrope, lactotroph, lactotropic cell, mammotrope, mammotrophic cell, mammotropic cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
somatotroph An acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin. Synonyms: somatotrope, somatotropic cell, somatrophic cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
external supporting cell of vestibular epithelium An auditory epithelial support cell located in the vestibular epithelium that has many hallmarks of glial cells. This cell type express glial markers such as vimentin, S100, glutamate-aspartate transporter, low affinity neurotrophin receptor p75, glial fibrillary acidic protein, and proteolipid protein. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
supporting cell of cochlea An epithelial supporting cell located in the cochlea. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
supporting cell of vestibular epithelium A supporting cell of the vestibular epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
external limiting cell of vestibular epithelium An external limiting cell found in the vestibular epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
peripheral blood mesothelial cell A mesothelial cell capable of circulating in the blood by first losing its squamous character. This cell can incorporate into the regenerating mesothelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
neural cell A cell that is part of the nervous system. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
connective tissue cell A cell of the supporting or framework tissue of the body, which includes adipose tissue, cartilage, and bone. In vertebrates, this cell arises chiefly from the embryonic mesoderm and, in cranial regions, from neural crest. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
embryonic cell (metazoa) A cell of the embryo. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
embryonic stem cell A stem cell of embryonic origin. Synonyms: ESC http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
amniocyte A cell of a fetus which is suspended in the amniotic fluid. Amniocytes are considered to arise from several tissues including fetal skin, the fetal urinary tract, umbilical cord, and the inner amniotic surface. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
basal-myoepithelial cell of mammary gland A myoepithelial cell that is part of a mammary gland and is located in the basal layer. During lactation, a basal-myoepithelial cell of mammary gland contracts under the stimulation of oxytocin. In humans, a basal-myoepithelial cell of mammary gland can be identified by high levels of CD49f and low levels of EpCAM. Synonyms: myoepithelial cell of mammary gland http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lactocyte A milk-producing glandular epithelial cell that is part of a mammary gland alveolus and differentiates from a luminal adaptive secretory precursor cell during secretory differentiation (also termed lactogenesis I). Following secretory activation (also termed lactogenesis II), a lactocyte is involved in the synthesis and/or transport of milk constituents including proteins, oligosaccharides, lactose, micronutrients, fat, hormones, immunoglobulins, and cytokines into the lumen of the lactating mammary gland. Synonyms: epithelial cell of lactiferous gland, lactaction-associated mammary epithelial cell, lactation-derived mammary cell, luminal cell of alveolus of lactiferous gland, mammary alveolar epithelial cell, mammary gland alveolar epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
luminal epithelial cell of mammary gland A mammary epithelial cell that occurs in the lumen of the ductal and alveoli structure in the breast. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mammary gland epithelial cell An epithelial cell of the mammary gland. Synonyms: breast epithelial cell, mammary epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
bronchial epithelial cell An epithelial cell of the bronchus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
basal epithelial cell of tracheobronchial tree An epithelial cell type that lacks the columnar shape typical for other respiratory epithelial cells. This cell type is able to differentiate into other respiratory epithelial cells in response to injury. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
undifferentiated cell of bronchus epithelium An undifferentiated columnar cell of the bronchus epithelium http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
multiciliated epithelial cell of the bronchus A multi-ciliated epithelial cell located in the bronchus epithelium, characterized by a columnar shape and motile cilia on its apical surface. Synonyms: ciliated epithelial cell of the bronchus http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
neural crest derived adipocyte An adipocyte derived from a neural crest cell. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
preadipocyte An undifferentiated fibroblast that can be stimulated to form a fat cell. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
brown preadipocyte A preadipocyte that is capable of differentiating into a brown adipocyte. This cell type expresses uncoupling protein-1, PPAR-gamma, PR-domain-containing 16; and PGC-1alpha (peroxisome proliferator-activated receptor-gamma (PPARgamma) coactivator-1alpha). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
buccal mucosa cell An endothelial cell that lines the oral cavitiy including the mucosa of the gums, the palate, the lip, and the cheek. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
keratinocyte stem cell A stem cell found in the basal layer of the epidermis, hair follicle, and sebaceous gland, characterised by its quiescent nature, high proliferative potential, and capacity for long-term self-renewal. This cell maintains epidermal homeostasis by producing transit-amplifying cells that differentiate to replenish the stratified squamous epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD56-positive, CD161-positive immature natural killer cell, human A natural killer cell that is developmentally immature, has the phenotype CD34-negative, CD56-positive, CD117-positive, CD122-positive,and CD161-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
prostate stem cell A prostate epithelial cell that is CD133-positive, CD44-positive, integrin A2beta3-high. This cell is a stem cell for the prostate epithelium. Synonyms: CD133-positive prostate epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
luminal cell of prostate epithelium The exocrine cell of the prostate, this epithelial cell secretes prostatic acid phosphotase and PSA, and is dependent on androgen hormones for survival. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
basal cell of prostate epithelium An undifferentiated cell of the prostate epithelium that lacks secretory activity. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
circulating endothelial cell A circulating endothelial cell of the phenotype CD146-positive, CD105-positive, CD45-negative. This cell type is indicative of recent vascular damage. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
decidual natural killer cell, human A natural killer cell subset that is found in the decidual of the uterus and is CD56-high, Galectin-1-positive and CD16-negative. This cell type represents the most abundant immune cell type in the decidual during the first trimester of pregnancy. Synonyms: dNK cell, decidual NK cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD56-negative, CD161-positive immature natural killer cell, human A natural killer cell that is developmentally immature, has the phenotype CD34-negative, CD56-negative, CD117-positive, CD122-positive,and CD161-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endocardial cell An endothelial cell that lines the intracavitary lumen of the heart, separating the circulating blood from the underlying myocardium. This cell type releases a number of vasoactive substances including prostacyclin, nitrous oxide and endothelin. Synonyms: endocardial endothelial cell, endothelial cell of endocardium http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
progenitor cell of endocrine pancreas A progenitor cell that is able to differentiate into the pancreas alpha, beta and delta endocrine cells. This cell type expresses neurogenin-3 and Isl-1. Synonyms: pancreatic endocrine progenitor, pancreatic islet progenitor cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
gestational hematopoietic stem cell A hematopoietic stem cell that exists during embryogenesis. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fetal liver hematopoietic progenitor cell A hematopoietic stem cell that resides in the fetal liver. In mice, this cell type is first observed at E10.5. This cell type is MHC-positive, HSA-positive, AA4.1-positive, CD45-positive, Sca-1 positive, CD150-positive, CD48-negative and CD244-negative. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
yolk sac hematopoietic stem cell A hematopoietic stem found in the yolk sac. In mice, this cell type is Sca-1-negative, CD45-negative, MHC-negative, HSA-positive, AA4.1-positive, CD44-positive. Synonyms: hemangioblast precursor http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
primitive red blood cell A large nucleated basophilic erythrocyte found in mammalian embryos. This cell type arises from the blood islands of yolk sacs and expresses different types of hemoglobins (beta-H1, gamma-1 and zeta) than adult erythrocytes. Considered a type of erythroblast as this cell type can enucleate in circulation. Synonyms: primitive erythroblast, primitive erythrocyte, primitive erythroid cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
primitive reticulocyte A primitive erythrocyte that has undergone enucleation. This cell type is 3-6 fold bigger than the fetal derived erythrocytes that they co-circulate with during fetal development. Expresses epsilon-gamma hemoglobin chains. Synonyms: megalocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fetal derived definitive erythrocyte A fetal liver derived enucleated erythrocyte. This erythrocyte resembles adult erythrocytes in that they are small (3- to 6- times smaller than primitive erythrocytes) and produce adult hemaglobins. Synonyms: macrocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pyrenocyte Derived from the Greek word pyren (the pit of a stone fruit), this is a transient nucleated cell type that results from exclusion of the nucleus from the primitive erythrocyte. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
placental hematopoietic stem cell A hematopoietic stem cell of the placenta. This cell type is first observed E10.5 This cell type may give rise to fetal liver hematopoietic stem cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
AGM hematopoietic stem cell A hematopoietic stem cell from the aorta-gonad-mesonephros region of the developing embryo. First seen at E10.5 in mouse embryos. May give rise to fetal liver HSC. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
primitive erythroid progenitor A progenitor cell that is capable of forming colonies of primitive erythrocytes in the blood island of the yolk sac. First arrive at E7.5 in mouse and expresses CD41. Synonyms: EryP-CFC, inner blood island hemangioblast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cerebellar granule cell precursor A cell located in the outermost proliferative zone of the external germinal layer that can differentiate into astroglial cells and granule cells. This cell type is glial fibrillary acidic protein-positive and HNK1-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
keratocyte A keratocyte is a specialized fibroblast residing in the cornea stroma that has a flattened, dendritic morphology; located between the lamellae with a large flattened nucleus, and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratan sulfate. Synonyms: corneal fibroblast, corneal keratocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cortical thymic epithelial cell An epithelial cell of the cortical portion of the thymus. Epithelial cells in this region are required for positive selection of CD8-positive T cells. Synonyms: cTEC http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
medullary thymic epithelial cell An epithelial cell of the medullary thymus. This cell type expresses a diverse range of tissue-specific antigens. This promiscuous gene expression is a cell-autonomous property of medullary epithelial cells and is maintained during the entire period of thymic T cell output. Synonyms: mTEC http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myometrial cell A smooth muscle cell of the myometrium that enlarges and stretches during pregnancy, and contracts in response to oxytocin. Synonyms: myometrium smooth muscle cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
trabecular meshwork cell An ocular connective tissue cell that is part of the eye's trabecular meshwork and is directly responsible for regulating the outflow of aqueous humor from the anterior chamber of the eye, thereby maintaining proper intraocular pressure. Synonyms: trabeculocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
respiratory tract epithelial cell An epithelial cell of the respiratory tract epithelium. These cells have an endodermal origin. Synonyms: airway epithelial cell, respiratory epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
respiratory tract goblet cell A simple columnar epithelial cell that secretes mucin. Rough endoplasmic reticulum, mitochondria, the nucleus, and other organelles are concentrated in the basal portion. The apical plasma membrane projects microvilli to increase surface area for secretion. Synonyms: respiratory goblet cell, respiratory mucosa goblet cells http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myotube A transversely striated, multinucleated syncytial muscle cell, formed by the fusion of myoblasts during muscle development. Synonyms: myofiber, myofibril http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
growth hormone releasing hormone secreting cell A peptide hormone secreting cell that secretes growth hormone releasing hormone. Synonyms: GHRH secreting cell, somatocrinin secreting cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ear hair cell A hair cell of the ear that contains the organs of balance and hearing. Synonyms: ear receptor cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Schwann cell precursor A multipotent progenitor cell that develops from a migratory neural crest cell. The schwann cell precursor is embedded among axons, with minimal extracellular space separating them from nerve cell membranes. This cell lacks a basal lamina, which distinguishes it from more mature Schwann cells. In rodents, cadherin-19 (Cdh19) serves as a specific marker for this developmental stage. Synonyms: Schwann cell precursor cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
non-myelinating Schwann cell A glial cell that ensheaths multiple small diameter axons in the peripheral nervous system. The non-myelinating Schwann cell is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has a basal lamina. Cells can survive without an axon present. These cells can de-differentiate into immature Schwann cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature Schwann cell A glial cell that develops from a Schwann cell precursor. The immature Schwann cell is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has a basal lamina. Cells can survive without an axon present. Immature Schwann cell can be found communally ensheathing large groups of axons. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature Vgamma2-positive fetal thymocyte A double negative thymocyte that has a T cell receptor consisting of a gamma chain containing a Vgamma2 segment, and a delta chain. This cell type is CD4-negative, CD8-negative and CD24-positive and is found in the fetal thymus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
meningothelial cell A neurecto-epithelial cell found in the arachnoid villi of dura mater. This cell type facilitates flow of cerebrospinal fluid into the blood. Synonyms: arachnoid cap cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
intermediate monocyte A monocyte that has characteristics of both patrolling and inflammatory monocytes. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD141-positive myeloid dendritic cell A myeloid dendritic cell found in the blood, lymph nodes, tonsil, bone marrow, and spleen that is CD141-positive (BDCA-3), XCR1-positive, and Clec9A-positive. This cell-type can cross-present antigen to CD8-positive T cells and can produce inteferon-beta. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD14-low, CD16-positive monocyte A patrolling monocyte that is CD14-low and CD16-positive. Synonyms: non-classical monocyte, human http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD14-positive, CD16-positive monocyte A CD14-positive monocyte that is also CD16-positive and CCR2-negative. Synonyms: CD16+ monocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD1c-positive myeloid dendritic cell A myeloid dendritic cell that is CD1c-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature dendritic epithelial T cell precursor A thymocyte that has a T cell receptor consisting of a gamma chain that has as part a Vgamma3 segment, and a delta chain. This cell type is CD4-negative, CD8-negative and CD24-negative. This cell-type is found in the fetal thymus with highest numbers occurring at E17-E18. Synonyms: mature DEC precursor, mature DETC precursor http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Peyer's patch B cell A resting mature B cell within the Peyer's patch that is CD19-positive, B220-positive, IgM-positive, AA4-negative, CD23-positive, CD43-negative, and CD5-negative. Synonyms: Peyers patch B cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature Vgamma2-positive fetal thymocyte A thymocyte that has a T cell receptor consisting of a gamma chain containing Vgamma2 segment, and a delta chain. This cell type is CD4-negative, CD8-negative and CD24-negative. This cell-type is found in the fetal thymus. Synonyms: fetal Vgamma2-positive http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fetal thymocyte A thymocyte found in the fetal thymus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
gamma-delta thymocyte A post-natal thymocyte expressing components of the gamma-delta T cell receptor. This cell type is always double-negative (i.e. CD4-negative, CD8-negative). Synonyms: gammadelta thymocyte, gd thymocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature Vgamma2-positive thymocyte A double negative post-natal thymocyte that has a T cell receptor consisting of a gamma chain containing a Vgamma2 segment, and a delta chain. This cell type is CD4-negative, CD8-negative and CD24-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature Vgamma2-positive thymocyte A thymocyte that has a T cell receptor consisting of a gamma chain containing Vgamma2 segment, and a delta chain. This cell type is CD4-negative, CD8-negative and CD24-negative. Synonyms: Vgamma2-positive http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature Vgamma2-negative thymocyte A double negative post-natal thymocyte that has a T cell receptor consisting of a gamma chain that does not contain a Vgamma2 segment, and a delta chain. This cell type is CD4-negative, CD8-negative and CD24-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature Vgamma2-negative thymocyte A thymocyte that has a T cell receptor consisting of a gamma chain that does not contain the Vgamma2 segment, and a delta chain. This cell type is CD4-negative, CD8-negative and CD24-negative. Synonyms: Vgamma2-negative http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pancreatic stellate cell A cell that is found in the periacinar space of the exocrine pancreas and in perivascular and periductal regions of the pancreas, and has long cytoplasmic processes that encircle the base of the acinus. Expresses several intermediate filament proteins including vimentin and nestin. Shares many of the characteristics of hepatatic stellate cells, but not stellate cells of the central nervous system. Upon activation, this cell type undergoes morphological and gene expression changes that make the cell suggestive of being a type of myofibroblast. Synonyms: PaSC, pancreas stellate cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
primitive erythroid lineage cell An immature or mature cell of the first erythroid lineage to arise during embryonic development. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hemangioblast A pluripotent cell in the yolk sac that can give rise to mesenchymal cells including erythrocytes and endothelial cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature T cell A T cell that expresses a T cell receptor complex and has completed T cell selection. Synonyms: CD3e-positive T cell, mature T-cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature T cell A T cell that has not completed T cell selection. Synonyms: immature T-cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
nucleated reticulocyte A reticulocyte that retains the nucleus and other organelles. Found in birds, fish, amphibians and reptiles. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
enucleated reticulocyte A reticulocyte lacking a nucleus and showing a basophilic reticulum under vital staining due to the presence of ribosomes. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
early T lineage precursor A pro-T cell that is lin-negative, CD25-negative, CD127-negative, CD44-positive and kit-positive. Synonyms: ETP, preT.ETP.Th http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
resting double-positive thymocyte A double-positive, alpha-beta thymocyte that is small and not proliferating. Synonyms: T.DP.sm.Th http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
double-positive blast A double-positive thymocyte that is large (i.e. has a high forward scatter signal in flow cytometry) and is actively proliferating. Synonyms: T.DPb.Th, activated double-positive thymocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD69-positive double-positive thymocyte A double-positive thymocyte that is CD69-positive and has begun positive selection. Synonyms: T.DP69+.Th http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD4-intermediate, CD8-positive double-positive thymocyte A double-positive thymocyte that is undergoing positive selection, has high expression of the alpha-beta T cell receptor, is CD69-positive, and is in the process of down regulating the CD4 co-receptor. Synonyms: T.4int8+.Th, T_4int8+_Th http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD4-positive, CD8-intermediate double-positive thymocyte A double-positive thymocyte that is undergoing positive selection, has high expression of the alpha-beta T cell receptor, is CD69-positive, and is in the process of down regulating the CD8 co-receptor. Synonyms: T.4+8int.Th, T_4+8int_Th http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD24-positive, CD4 single-positive thymocyte A CD4-positive, CD8-negative thymocyte that is CD24-positive and expresses high levels of the alpha-beta T cell receptor. Synonyms: CD24-positive, CD4 single-positive semimature thymocyte, T.4SP24int.Th http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD69-positive, CD4-positive single-positive thymocyte A CD4-positive, CD8-negative thymocyte that expresses high levels of the alpha-beta T cell receptor and is CD69-positive. Synonyms: T.4SP69+.Th, intermediate CD4-single-positive http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD24-positive, CD8 single-positive thymocyte A CD8-positive, CD4-negative thymocyte that is CD24-positive and expresses high levels of the alpha-beta T cell receptor. Synonyms: CD24-positive, CD8 single-positive semimature thymocyte, T.8SP24int.Th http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD69-positive, CD8-positive single-positive thymocyte A CD8-positive, CD4-negative thymocyte that expresses high levels of the alpha-beta T cell receptor and is CD69-positive. Synonyms: T.8SP69+.Th, intermediate CD8-single-positive http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature CD4 single-positive thymocyte A mature CD4-positive, CD8-negative alpha-beta T cell found in the thymus that is CD24-low and has high expression of the T cell receptor. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature CD8 single-positive thymocyte A mature CD8-positive, CD4-negative alpha-beta T cell found in the thymus that is CD24-low and has high expression of the T cell receptor. Synonyms: T.8SP24-.Th http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tether cell A specialized hair cell that has an elongated kinocilium upon which an otolith accretes. The tether cell then anchors the otolith in place. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mammary stem cell A multi-fate stem cell that is the source of cells for growth of the mammary gland during puberty and gestation. This cell type gives rise to both the luminal and myoepithelial cell types of the gland, and have been shown to have the ability to regenerate the entire organ in mice. This cell type also plays an important role in carcinogenesis of the breast. This cell type is Lin-, CD24-positive, CD29-hi. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
oligodendrocyte precursor cell A proliferative and migratory glial progenitor cell that derives from a neural stem cell and resides within the central nervous system. It possesses the capacity to differentiate into a committed oligodendrocyte progenitor (COP) through a well-defined series of maturation steps, ultimately giving rise to a myelinating oligodendrocyte (MOL). In mice and humans, it is characterized by the expression of specific molecular markers, including Pdgfra, Cspg4 (also known as NG2) and Olig2. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD4-negative, CD8-alpha-negative, CD11b-positive dendritic cell CD4-negative, CD8-alpha-negative, CD11b-positive dendritic cell is a conventional dendritic cell that is CD11b-positive, CD4-negative, CD8-alpha-negative and is CD205-positive. Synonyms: DC.8-4-11b+, spleen double-negative dendritic cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epidermal Langerhans cell A Langerhans cell that is in the epidermis and is CD45-positive, MHCII-positive, and CD11b-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
langerin-positive dermal dendritic cell A dermal dendritic cell that is langerin-positive and CD103-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
langerin-negative dermal dendritic cell A dermal dendritic cell that is langerin-negative, CD103-negative, and CD11b-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD8-alpha-negative thymic conventional dendritic cell A conventional thymic dendritic cell that is CD8-alpha-negative. Synonyms: DC.8-.Th http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD103-positive dendritic cell A conventional dendritic cell that is CD103-positive. This cell type is usually found in non-lymphoid tissue. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
adipose dendritic cell A F4/80-negative dendritic cell located in adipose tissue. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
SIRPa-positive adipose dendritic cell An adipose dendritic cell that is SIRPa-positive. Synonyms: DC.SIRPa+.Ad http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
SIRPa-negative adipose dendritic cell An adipose dendritic cell that is SIRPa-negative. Synonyms: DC.SIRPa-.Ad http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD11b-positive dendritic cell A conventional dendritic cell that expresses CD11b (ITGAM). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
small intestine serosal dendritic cell A CD11b-positive dendritic cell located in the serosal portion of the small intestine epithelium. This cell type is CD45-positive, MHC-II-positive, CD11c-low, CD103-negative. Synonyms: DC.11cloSer.SI http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Gr1-high myeloid suppressor cell A myeloid suppressor cell that is Gr1-high and CD11c-negative. Synonyms: MDS.Gr1hi http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Gr1-low myeloid suppressor cell A myeloid suppressor cell that is Gr1-low and CD11c-positive. Synonyms: MDS.Gr1lo http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
bone marrow macrophage A tissue-resident macrophage located in the bone marrow. This cell type is B220-negative, CD3e-negative, Ly-6C-negative, CD115-positive, F4/80-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
adipose macrophage A macrophage located in adipose tissue that is CD45-positive, CD11c-positive, and SIRPa-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
F4/80-negative adipose macrophage An adipose macrophage that does not express F4/80but is MHC-II-positive. This cell type exhibits autofluorescence under typical flow cyometry conditions. Synonyms: MF.Autofl.Ad http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
F4/80-positive adipose macrophage An adipose macrophage that does not express MHC-II but is F4/80-positive. Synonyms: MF.F480+.Ad http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
nasal mucosa goblet cell A goblet cell located in the nasal epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
peritubular myoid cell The flattened smooth myoepithelial cells of mesodermal origin that lie just outside the basal lamina of the seminiferous tubule. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
dermal melanocyte A melanocyte that produces pigment in the dermis. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hair follicle melanocyte A melanocyte that produces pigment within the hair follicle. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial melanocyte A melanocyte that produces pigment in the epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
retinal melanocyte A melanocyte of the retina. This cell type is distinct from pigmented retinal epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
strial intermediate cell A melanocyte located between the epithelial marginal cell layer and the mesodermal basal cell layer within the intrastrial space; the predominant cellular component of the electrogenic machinery that generates an endocochlear potential (80-100 mV) . http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cutaneous/subcutaneous mechanoreceptor cell A neuronal receptor that respond to mechanical pressure or distortion in the skin. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
trophoblast giant cell A trophoblast cell that has a large volume of cytoplasm, is polyploid and is usually mononuclear but is also occasionally multi-nucleate. This cell type is important in establishing maternal physiology and remodeling of the vasculature of the placenta. Synonyms: giant trophoblast cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
double negative thymocyte A thymocyte that lacks expression of CD4 and CD8. Synonyms: CD4-CD8- T cell, double negative T cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
organ of Corti supporting cell A supporting cell of the organ of Corti. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
auditory epithelial cell A specialized cell involved in auditory sensory perception. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
strial marginal cell A polarized columnar cell that covesr the lateral surface of the cochlear duct, secretes potassium ions and forms a continuous sheet in contact with the endolymph; marginal cells form extensive interdigitations with the basal and intermediate cells in the normal adult stria. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
strial basal cell A polarized cell that is juxtaposed to fibrocytes in the underlying spiral ligament. This cell type secretes potassium ions derived from fibrocytes through gap junctions. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cardiocyte A cell located in the heart, including both muscle and non muscle cells. Synonyms: heart cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fetal cardiomyocyte A fetal and neonatal heart cell that undergoes proliferation and is not yet terminally differentiated into a binucleate or a multinucleate cardiac myocyte. Synonyms: embryonic cardiomyocyte, neonatal cardiomyocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
intraepithelial lymphocyte A tissue-resident lymphocyte located within the epithelial layer of mucosal tissues, particularly within the gastrointestinal, respiratory, and reproductive tracts. Characterised by permanent residency, this cell typically expresses CD103 (integrin alpha-E), which binds to E-cadherin on epithelial cells, enabling epithelial retention in both mice and humans. Phenotypically, IEL displays an activated, antigen-experienced state characterised by the constitutive expression of cytotoxic molecules (granzyme B, perforin) and innate-like receptors (such as NKG2D), enabling rapid, localised surveillance and immediate response to epithelial stress. Synonyms: IEL, intraepithelial T cell, intraepithelial T-cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
primary trophoblast giant cell A trophoblast giant cell derived from the mural trophectoderm. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
secondary trophoblast giant cell A trophoblast giant cell that is derived from ectoplacental cone and, later in gestation, the spongiotrophoblast. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
spongiotrophoblast cell A trophoblast cell that arises in the junctional zone (basal plate) of the placenta. Synonyms: spongiotrophoblast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
P enteroendocrine cell A P/D1 enteroendocrine cell that is Grimelius positive and stores bombesin-like polypeptide. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type D1 enteroendocrine cell A P/D1 enteroendocrine cell that is argyrophilic and stores vasoactive intestinal polypeptide. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type M enteroendocrine cell An enteroendocrine cell of the small intestine that secretes motilin. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
adventitial cell A cell of the adventitial layer of ductal structures such as the uterer, defent duct, biliary duct, etc http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
enteric smooth muscle cell A smooth muscle cell of the intestine. Synonyms: intestinal smooth muscle cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
liver CD103-negative dendritic cell A CD11b-positive dendritic cell that is CD11b-high, CD45-positive, MHC-II-positive and CD103-negative. Synonyms: DC.103-11b+.Lv http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
liver CD103-positive dendritic cell A CD11b-positive dendritic cell that is CD11b-low, CD45-positive, MHC-II-high and CD103-positive that is located in the liver. Synonyms: DC.103+11b-.Lv http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
langerin-positive lymph node dendritic cell A dermal dendritic cell isolated from skin draining lymph nodes that is langerin-positive, MHC-II-positive, and CD4-negative and CD8a-negative. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
langerin-negative, CD103-negative lymph node dendritic cell A dermal dendritic cell isolated from skin draining lymph nodes that is langerin-negative, MHC-II-positive, and CD4-negative and CD8a-negative. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD103-positive, langerin-positive lymph node dendritic cell A langerin-positive lymph node dendritic cell that is CD103-positive and CD11b-low. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD103-negative, langerin-positive lymph node dendritic cell A langerin-positive lymph node dendritic cell that is CD103-negative and CD11b-high. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD11b-low, CD103-negative, langerin-negative lymph node dendritic cell A langerin-negative lymph node dendritic cell that is CD103-negative and CD11b-low. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD11b-high, CD103-negative, langerin-negative lymph node dendritic cell A langerin-negative lymph node dendritic cell that is CD103-negative and CD11b-high. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Vgamma5-positive CD8-alpha alpha positive gamma-delta intraepithelial T cell A CD8-alpha alpha positive gamma-delta intraepithelial T cell that expresses a TCR encoded in part by the Vgamma5 gene segment. Synonyms: tgd.vg5+.IEL http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Vgamma5-negative CD8-alpha alpha positive gamma-delta intraepithelial T cell A CD8-alpha alpha positive gamma-delta intraepithelial T cell that does not express a TCR partially encoded by the Vgamma5 gene segment. Synonyms: tgd.vg5-.IEL http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
interrenal norepinephrine type cell An interrenal chromaffin cell found in teleosts that contain heterogeneous vesicles with electron-dense granules located asymmetrically within the vesicular membrane. Synonyms: interrenal noradrenaline type cell, type n interrenal cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
interrenal chromaffin cell A chromaffin cell interspersed among the interrenal epithelial layer of the anterior kidney of teloest fish. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
interrenal epinephrin secreting cell An interrenal chromaffin cell found in teleosts that contain small, homogeneous electron-lucent granules that are separated from the vesicular membrane by a visible halo. Synonyms: type a interrenal cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney epithelial cell An epithelial cell of the kidney. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
interrenal epithelial cell An interrenal epithelial kidney cell is an epithelial cell found in the anterior kidney of teleosts fish. This cell type is arranged in layers around the posterior cardinal vein and contains many mitochondria with tubulovesicular cristae. Interrenal chromaffin cells are interspersed among the tissue layer created by this cell type. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
subcutaneous adipocyte An adipocyte that is part of subcutaneous adipose tissue. Synonyms: subcutaneous fat cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
renal filtration cell A renal filtration cell is a specialized cell of the renal system that filter fluids by charge, size or both. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesonephric podocyte A specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells in the mesonephros. Synonyms: mesonephric glomerular visceral epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
metanephric podocyte A specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells in the metanephros. Synonyms: metanephric glomerular visceral epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD14-positive dermal dendritic cell A dermal dendritic cell that is CD1a-negative and CD14-positive. Synonyms: CD14+ dermal DC http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature CD14-positive dermal dendritic cell An immature CD14-positive dermal dendritic cell is CD80-low, CD86-low, and MHCII-low. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature CD14-positive dermal dendritic cell A mature CD14-positive dermal dendritic cell is CD80-high, CD86-high, MHCII-high and is CD83-positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD1a-positive dermal dendritic cell A dermal dendritic cell that is CD1a-positive and CD14-negative. Synonyms: CD1a+ dermal DC http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature CD1a-positive dermal dendritic cell An immature CD1a-positive dermal dendritic cell is CD80-low, CD86-low, and MHCII-low. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature CD1a-positive dermal dendritic cell A mature CD1a-positive dermal dendritic cell is CD80-high, CD83-positive, CD86-high, and MHCII-high. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD16-positive myeloid dendritic cell A myeloid dendritic cell found in the blood that is CD16-positive. Synonyms: CD16+ mDC, CD16-mDC http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature CD16-positive myeloid dendritic cell An immature CD16-positive myeloid dendritic cell is CD80-low, CD86-low, and MHCII-low. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature CD16-positive myeloid dendritic cell A mature CD16-positive myeloid dendritic cell is CD80-high, CD83-positive, CD86-high, and MHCII-high. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of cervix An epithelial cell of the cervix. Synonyms: cervical canal epithelial cell, cervical canal of uterus epithelial cell, cervix epithelial cell, cervix of uterus epithelial cell, epithelial cell of cervical canal, epithelial cell of cervical canal of uterus, epithelial cell of cervix of uterus, epithelial cell of neck of uterus, epithelial cell of uterine cervix, neck of uterus epithelial cell, uterine cervix epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of amnion An epithelial cell that is part of the amnion. Synonyms: amniotic epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
amnion mesenchymal stem cell A mesenchymal stem cell of the amnion membrane. Synonyms: amniotic membrane stem cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
intrahepatic cholangiocyte An epithelial cell of the intrahepatic portion of the bile duct. These cells are flattened or cuboidal in shape, and have a small nuclear-to-cytoplasmic ratio relative to large/extrahepatic cholangiocytes. Synonyms: small bile duct cholangiocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
aortic smooth muscle cell A smooth muscle cell of the aorta. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesenchymal stem cell of the bone marrow A mesenchymal stem cell that is part of the bone marrow. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
chorionic membrane mesenchymal stem cell A mesenchymal stem cell of the chorionic membrane. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
vein endothelial cell An endothelial cell that is part of the vein. Synonyms: endothelial cell of vein, venous endothelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
aortic endothelial cell An arterial endothelial cell that is part of the aorta endothelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
thoracic aorta endothelial cell An endothelial cell that is part of the thoracic endothelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
embryonic blood vessel endothelial progenitor cell An endothelial progenitor cell that participates in angiogenesis during development. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of the aortic adventitia A fibroblast of the aortic adventitia. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of cardiac tissue A fibroblast that is part of the heart. Synonyms: cardiac fibroblast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of choroid plexus A fibroblast that is part of the choroid plexus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of the conjunctiva A fibroblast that is part of the conjuctiva of the eye. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of dermis Any skin fibroblast that is part of some dermis. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of gingiva Any fibroblast that is part of some gingiva. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of lung A fibroblast that is part of lung. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of lymphatic vessel A fibroblast of the lymphatic system. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of mammary gland A fibroblast that is part of the mammary gland. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of periodontium A fibroblast of the periodontium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of pulmonary artery A fibroblast of pulmonary artery. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of villous mesenchyme A fibroblast that is part of villous mesenchyme. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hair follicle cell An animal cell that is part of a hair follicle. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
inner root sheath cell An epithelial cell that resides in the inner root sheath of the hair follicle. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
outer root sheath cell An epithelial cell that is part of the outer root sheath. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hair germinal matrix cell An epidermal cell that is part of the germinal matrix. Synonyms: trichocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
intestinal epithelial cell An epithelial cell of the lining of the intestine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
nucleus pulposus cell of intervertebral disc A connective tissue cell of the nucleus pulposus cell of intervertebral disc. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
iris pigment epithelial cell A pigment cell located in the epithelium of the iris. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
dark melanocyte A melanocyte that appears darker due to content or amount of melanin granules. Synonyms: melanotic melanocyte, melanotic melanophore http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
light melanocyte A melanocyte that appears lighter in color. Synonyms: amelanotic melanocyte, amelanotic melanophore http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesenchymal stem cell of Wharton's jelly A mesenchymal stem cell that is part of Wharton's jelly. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesenchymal stem cell of umbilical cord A mesenchymal stem cell of the umbilical cord. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesenchymal stem cell of adipose tissue A mesenchymal stem cell of adipose tissue. Synonyms: mesenchymal stem cell of adipose http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hepatic mesenchymal stem cell A mesenchymal stem cell of liver. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
vertebral mesenchymal stem cell A mesenchymal stem cell of the vertebrae. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stromal cell of pancreas A stromal cell of the pancreas. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
central nervous system pericyte A pericyte of the central nervous system. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
perineurial cell A glial cell that is part of the perineurium. This cell type has thin long bipolar cytoplasmic processes, pinocytotic vesicles, fragments of external lamina and/or external lamina-like material, attachment plaques, and desmosome-like junctions. Perineurial cells historically have been referred to as fibroblasts because of shape; however, unlike fibroblasts, a perineurial cell: does not have a compact nucleus and large endoplasmic reticulum; does have a double basement membrane opposed to a single basal lamina; is carefully joined to other perineurial cells by tight junctions into a single sheet as opposed to arranged in a large mass; and finally, can surround a small axon bundle at a nerve terminal whereas a fibroblast cannot. Synonyms: perineurial glial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
placental epithelial cell An epithelial cell of the placenta. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesenteric preadipocyte A preadipocyte found in mesenteric tissue. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
omentum preadipocyte A preadipocyte that is part of an omentum. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
preadipocyte of the breast A preadipocyte that is part of the breast. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
perirenal preadipocyte A preadipocyte that is part of a perirenal fat tissue. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
visceral preadipocyte A preadipocyte that is part of visceral tissue. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
subcutaneous preadipocyte A preadipocyte that is part of subcutaneous tissue. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
renal cortical epithelial cell An epithelial cell of the kidney cortex. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
retinal blood vessel endothelial cell A blood vessel endothelial cell that is part of the retina. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
retinal pigment epithelial cell An epithelial cell of the retinal pigmented epithelium. Synonyms: RPE http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle cell of the umbilical vein A smooth muscle cell of the umbilical vein. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle cell of the brachiocephalic vasculature A smooth muscle cell of the bachiocephalic vasculature. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle cell of the brain vasculature A vascular associated smooth muscle cell of the brain vasculature. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle cell of the pulmonary artery A smooth muscle of the pulmonary artery. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle cell of the coronary artery A smooth muscle cell of the coronary artery. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle cell of the internal thoracic artery A smooth muscle of the internal thoracic artery. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle cell of the umbilical artery A smooth muscle cell of the umbilical artery. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle cell of the subclavian artery A smooth muscle cell of the subclavian artery. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle cell of the carotid artery Smooth muscle cell of the carotid artery. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle cell of bladder A smooth muscle cell of the bladder. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
bronchial smooth muscle cell Any smooth muscle cell that is part of some bronchus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle cell of the esophagus A smooth muscle cell of the esophagus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle cell of trachea A smooth muscle cell of the trachea. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
uterine smooth muscle cell A smooth muscle cell of the uterus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
annulus pulposus cell Any connective tissue cell that is part of some annulus fibrosus disci intervertebralis. Synonyms: anulus pulposus cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
astrocyte of the cerebellum An astrocyte of the cerebellum. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hippocampal astrocyte An astrocyte that is part of the hippocampus. Synonyms: astrocyte of the hippocampal formation, astrocyte of the hippocampus http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
astrocyte of the cerebral cortex A transcriptomically distinct astrocyte that is found in the cerebral cortex. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
astrocyte of the spinal cord An astrocyte of the spinal cord. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
migratory enteric neural crest cell A neural crest cell that gives rise to cells of the enteric nervous system. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
adipocyte of omentum tissue An adipocyte that is part of omentum tissue. Synonyms: omental adipocyte, omental fat cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
perirenal adipocyte An adipocyte of perirenal fat tissue. Synonyms: perirenal adipocyte cell, perirenal fat cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
adipocyte of breast An adipocyte that is part of the breast. Synonyms: breast adipocyte, fat cell of breast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endothelial cell of umbilical vein An endothelial cell of the umbilical vein. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
adult endothelial progenitor cell An adult angioblastic cell released from the bone marrow, or from the kidney in some teleost species, capable of blood circulation and participation in angiogenesis by differentiating into blood vessel endothelial cells. Synonyms: EPC http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
skin fibroblast A fibroblast of skin. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
gingival epithelial cell Any stratified squamous epithelial cell that is part of some gingival epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
prostate stromal cell A stromal cell of the prostate. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
acinar cell of salivary gland An acinar cell that is part of the salivary gland epithelium, responsible for synthesizing and secreting the primary saliva essential for oral digestion, antimicrobial defense, and mucosal immunity. It features apical-basal polarity with apical secretory granules, and tight junctions that maintain polarity and regulate calcium-dependent saliva exocytosis triggered by parasympathetic and sympathetic signals (Ambudkar, 2015). This cell functions in coordination with contractile myoepithelial cells, which aid saliva flow through the ducts into the oral cavity (Khan et al., 2022). In mice and humans, acinar cell development relies on the transcription factor SOX2 (Emmerson et al., 2017), with self-renewal achieved primarily through acinar cell self-duplication and supported by progenitor populations during injury and regeneration (Aure et al., 2016). Synonyms: salivary acinar cell, salivary gland acinar cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
paneth cell of the appendix A paneth cell of the appendix. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
seminiferous tubule epithelial cell A cell of the seminiferous tubule epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature astrocyte An immature astrocyte. Synonyms: immature astrocytic glia http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature astrocyte A mature astrocyte that is capable of producing cytokines. Synonyms: activated astrocyte, mature astrocytic glia http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature microglial cell An immature microglial cell with a ramified morphology. Synonyms: immature microglia, quiescent microglia, resting microglia http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature microglial cell A mature microglial cell that has changed shape to an amoeboid morphology and is capable of cytokine production and antigen presentation. Synonyms: activated microglia, mature microglia, reactive microglia http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of upper respiratory tract Any epithelial cell that is part of some upper respiratory tract epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of lower respiratory tract Any epithelial cell that is part of some lower respiratory tract epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
respiratory basal cell A basal cell in the respiratory tract. Synonyms: airway basal cell, airway basal stem cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of anal column An epithelial cell of the anal column. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
nonkeratinized epithelial cell of anal column A nonkeratinized epithelial cell of the anal canal. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
nonkeratinized epithelial cell of inferior part of anal canal A nonkeratinized cell epithleial cell of the inferior part of the anal canal. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
keratinized epithelial cell of the anal canal An epithelial cell of the anal canal that is keratinized. This cell type is found towards the lower, rectal end of the anal canal. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
bronchioalveolar stem cell A respiratory stem cell found at the junction of the terminal (conductive) bronchiole and the respiratory bronchiole. This cell types gives rise to alveolar cell types and club cells in response to lung injury. This cell type expresses markers Scgb1a1 and Sftpc. Synonyms: BASC, basal epithelial cell of bronchioalveolar duct junction http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
amniotic stem cell An amniotic stem cell is a mesenchymalstem cell extracted from amniotic fluid. Amniotic stem cells are able to differentiate into various tissue type such as skin, cartilage, cardiac tissue, nerves, muscle, and bone http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
amniotic epithelial stem cell An epithelial fate stem cell derived form the amnion membrane. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of esophageal gland proper An epithelial cell of the esophageal gland proper. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of esophageal cardiac gland An epithelial cell of the esophageal cardiac gland that occurs both in the proximal and distal esophagus, within the lamina propia. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
nonkeratinized cell of stratum corneum of esophageal epithelium An epithelial cell of stratum corneum of esophageal epithelium that lacks keratin. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endo-epithelial cell of tympanic part of viscerocranial mucosa An endothelial cell of viscerocranial mucosa that is part of the tympanic region of the viscerocranial mucosa. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endo-epithelial cell of pharyngotympanic part of viscerocranial mucosa An endocranial viscerocranial mucosa cell that is part of viscerocranial mucosa. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endothelial cell of venous sinus of spleen An endothelial cell that is part of the venous sinus of spleen. This endothelial cell has an elongated, spindle-shaped, flattened morphology that is parallel to long axis of sinus. This cell type rests on a basement membrane interrupted by numerous narrow slits. Synonyms: stave cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endothelial cell of high endothelial venule A venule endothelial cell that is cubodial, expresses leukocyte-specific receptors, and allows for passage of lymphocytes into bloodstream. Synonyms: HEV cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
squamous endothelial cell A squamous shaped endothelial cell. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of stratum corneum of esophageal epithelium An epithelial cell of stratum corneum of esophageal epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of stratum spinosum of esophageal epithelium An epithelial cell of stratum spinosum of esophageal epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
glandular endometrial unciliated epithelial cell A glandular epithelial cell of the endometrium. Following ovulation, these cells secrete a glycogen-rich substance known as histotroph or uterine milk, which nourishes the embryo if implantation occurs. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
glandular cell of esophagus A glandular epithelial cell of the esophagus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
glandular cell of the large intestine A glandular epithelial cell of the large intestine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
glandular epithelial cell of stomach A glandular epithelial cell that is part of the stomach. Synonyms: glandular cell of stomach http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
luminal cell of acinus of lactiferous gland A luminal epithelial cell of mammary gland located in acinus of structure. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
luminal cell of lactiferous terminal ductal lobular unit A luminal cell of terminal ducts, i.e.e the terminal branch of a lactiferous duct which alveolar cells drain into. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
luminal cell of lactiferous duct A luminal epithelial cell of the lactiferous duct. This cuboidal epithelial cell expresses keratin-18 and is estrogen-receptor alpha positive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myocardial endocrine cell of atrium A myocardial endocrine cell that is part of the atrium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cardioblast A stem cell that can give rise to multiple cell types (i.e. smooth muscle, endothelial) in the developing heart. Synonyms: cardiovascular progenitor cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
otic fibrocyte A mesenchymal cell within the inner ear, specifically localised to supportive connective tissues such as the spiral ligament and spiral limbus. This cell has specialised structural and molecular adaptations, and it contributes to the homeostasis of the cochlear environment by participating in ionic regulation crucial for auditory function. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type II spiral ligament fibrocyte A spiral ligament fibrocyte that is located near the spiral prominence between the basilar crest and the stria and plays an important role in potassium recycling by actively pumping K+ from the extracellular space and facilitating transcellular K+ transport through gap junctions toward Type I fibrocytes. In mice, Type II fibrocytes express connexin 26 (Gjb2) and connexin 30 (Gjb6) as part of the mesenchymal gap junction system, as well as the Na‑K‑2Cl cotransporter NKCC1. Synonyms: type 2 spiral ligament fibrocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type V spiral ligament fibrocyte A spiral ligament fibrocyte located in the suprastrial region above the stria vascularis, distinguished from other fibrocytes by their unique expression of COX-1 in guinea pigs and end-foot structures that directly contact capillaries (Dai and Shi, 2011). This fibro-vascular coupling enables type V fibrocytes to regulate cochlear blood flow by translating Ca²⁺ signals into capillary vasodilation via COX-1-derived prostaglandins. This cell also participates in K⁺ recycling, expressing Na,K-ATPase (ATP1A1, ATP1B1) in mice and humans, and connexin 26/30 gap junctions enabling intercellular K⁺ transport within the spiral ligament syncytium (Peeleman et al., 2020). Synonyms: type V otic fibrocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type IV spiral ligament fibrocyte A spiral ligament fibrocyte that is located in the triangular space inferior to the crista basilaris (basilar crest). This cell is spindle-shaped and expresses NKCC1 but minimal to no Na,K-ATPase (ATP1A1, ATP1B1) in mice and humans, and lacks connexin 26/30 in mice, indicating it does not participate in K⁺ recycling, unlike type II fibrocytes. Type IV fibrocyte is uniquely characterised by strong expression of connective tissue growth factor (CTGF) in mice, suggesting roles in tissue remodelling and paracrine signalling to other cochlear cells. Synonyms: type 4 spiral ligament fibrocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type III spiral ligament fibrocyte A spiral ligament fibrocyte that is located in the deepest part of the inferior spiral ligament, directly lining the bony otic capsule. Distinguished from ion-transporting Type I and II fibrocytes, it utilises actin-myosin stress fibres and anchoring interactions to regulate basilar membrane tension. It has an elongated morphology, is most numerous in the basal, high-frequency cochlea, and expresses contractile and cytoskeletal proteins in mice, including α‑smooth muscle actin, non‑muscle myosin II, caldesmon, and the water channel Aquaporin‑1(Mahendrasingam et al., 2011; Kelly et al., 2012). Synonyms: tension fibroblast, type 3 spiral ligament fibrocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type I spiral ligament fibrocyte A spiral ligament fibrocyte that underlies the stria vascularis and is part of a mesenchymal gap junction network that regulates ionic homeostasis of the endolymph. In mice, expression of connexin 26 (Gjb2) and connexin 30 (Gjb6) serves as a distinguishing molecular signature. Synonyms: type 1 spiral ligament fibrocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endothelial stalk cell An endothelial stalk cell is a specialized endothelial cell that follows behind the tip cell of an angiogenic sprout. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
retinal progenitor cell A multi-fate stem cell that can give rise to different retinal cell types including rod and cone cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tongue muscle cell A skeletal muscle cell that is part of the tongue. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
naive regulatory T cell A regulatory T cell that has not encountered antigen. Synonyms: naive regulatory T lymphocyte, naive regulatory T-cell, naive regulatory T-lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
memory regulatory T cell A CD4-positive, CD25-positive alpha-beta regulatory T cell that has encountered antigen. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
natural helper lymphocyte A lymphocyte found in adipose tissue that lacks lineage markers of other lymphocytes but is capable of mediating TH2 cytokine responses. This cell type is found in fat associated lymphoid clusters, proliferates in response to IL2 and produce large amounts of TH2 cytokines such as IL5, IL6 and IL13 http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
PP cell of intestine A PP cell found in intestine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney cortical cell A cell that is part of a cortex of kidney. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
bistratified retinal ganglion cell A retinal ganglion cell that has dendrites stratified in two layers of the inner-plexiform layer. Synonyms: retinal ganglion D cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
L cone cell A cone cell that detects long wavelength light. Exact peak of spectra detected differs between species. In humans, spectra peaks at 564-580 nm. Synonyms: L cone, L-cone, long wavelength sensitive cone, long- (L) wavelength-sensitive cone, long-wavelength cone http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
M cone cell A cone cell that detects medium wavelength light. Exact peak of spectra detected differs between species. In humans, spectra peaks at 534-545 nm. Synonyms: M cone, M-cone, middle wavelength sensitive cone, middle- (M) wavelength-sensitive cone, middle-wavelength-sensitive (M) cone http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
S cone cell A cone cell that detects short wavelength light. Exact peak of spectra detected differs between species. In humans, spectra peaks at 420-440 nm. Synonyms: S cone, S-(short-wavelength sensitive) cone, S-cone, S-cone photoreceptor, short wavelength sensitive cone, short- (S) wavelength-sensitive cone, short-wavelength sensitive cone, short-wavelength-sensitive (S) cone http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
UV cone cell A cone cell that detects ultraviolet (UV) wavelength light. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
510 nm-cone A cone whose sensitivity measurements have an average spectral peak of 510 nm. These cones are described in rat. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
360 nm-cone A cone whose sensitivity measurements have an average spectral peak of 358.2 nm. These cones are described in rat. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type 3a cone bipolar cell A type of type 3 cone bipolar cell with distinctive curly dendrites. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type 3b cone bipolar cell A type of type 3 cone bipolar cell with distinctive crescent-shaped dendrites. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type 5a cone bipolar cell A type 5 cone bipolar cell with narrowly stratified post synaptic terminals. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type 5b cone bipolar cell A type 5 cone bipolar cell with diffuse axonal branches. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
H1 horizontal cell A horizontal cell with a large cell body, thick dendrites, and a large dendritic arbor. Synonyms: A Horizontal Cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
H2 horizontal cell A horizontal cell with a small cell body, thin dendrites, and small dendritic arbor. Synonyms: B Horizontal Cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
A2 amacrine cell A bistratifed retinal amacrine cell with a small dendritic field, dendrite stratification in S1-S2, and a second dendrite stratification in S5. This cell type releases the neurotransmitter glycine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
flag amacrine cell An amacrine cell with a small, asymteric dendritic field. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
flag A amacrine cell A flag amacrine cell with post-synaptic terminals in S2 and S3. This cell type releases the neurotransmitter glycine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
flag B amacrine cell A flag amacrine cell with post-synaptic terminals in S3, S4, and S5. This cell type releases the neurotransmitter glycine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
AB diffuse-1 amacrine cell A amacrine cell with a small dendritic field and post-synaptic terminals in S1, S2, S3, and S4. AB diffuse-1 amacrine cells have a tent-shaped dendritic arbor and undulate dendrites. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
AB diffuse-2 amacrine cell A broadly stratifying amacrine cell that has a small dendritic field and post-synaptic terminals in S2 and S3. This cell type releases the neurotransmitter glycine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
spider amacrine cell A broadly stratifying amacrine cell with a small dendritic field, straight dendrites and post-synaptic terminals in S1, S2, and S3. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
monostratified amacrine cell An amacrine cell with a small dendritic field with post-synaptic terminals in S3 and S4. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
flat bistratified amacrine cell A bistratified amacrine cell with a small dendritic field. Flat bistratified amacrine cells have post-synaptic terminals both on the border of S1 and S2, and on the border of S3 and S4. This cell type releases the neurotransmitter glycine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
broad diffuse amacrine cell An amacrine cell with a small dendritic field that has post-synaptic terminals in S1, S2, S3, and S4. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
A2-like amacrine cell A bistratified amacrine cell with a small dendritic field that has dendrite stratification in S2, and in S3 and S4. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
diffuse bistratified amacrine cell A bistratified amacrine cell with a small dendritic field that has post-synaptic terminals in S1 and the border of S1-S2, and termination of a second arbor within the border of S2-S3 and S3. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
recurving diffuse amacrine cell A broadly stratifying amacrine cell with a small dendritic field and a complex dendritic arbor. Recurving diffuse amacrine cells have post-synaptic terminals in S2, S3, and S4. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
starburst amacrine cell An amacrine cell with a flat dendritic arbor and a medium dendritic field. Starburst amacrine cells have post-synaptic terminals in S2. This cell type releases the neurotransmitters gamma-aminobutyric acid (GABA) and acetylcholine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
DAPI-3 amacrine cell An amacrine cell with a medium dendritic field and post-synaptic terminals that stratify at S2, with a second stratification that occurs in S3 and S4. This cell type releases the neurotransmitter glycine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
diffuse multistratified amacrine cell An amacrine cell with a medium dendritic field and post-synaptic terminals in S2, and in S3-S4. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
AB broad diffuse-1 amacrine cell An amacrine cell with a medium dendritic field and post-synaptic terminals in S2 and S3. This cell type releases the neurotransmitter gamma-aminobutyric acid (GABA). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
AB broad diffuse-2 amacrine cell An amacrine cell with a medium dendritic field and post-synaptic terminals in S2, S3, and S4. This cell type releases the neurotransmitter gamma-aminobutyric acid (GABA). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fountain amacrine cell A retinal amacrine cell with a medium dendritic field and post-synaptic terminals in S1, S2, S3, and S4. This cell type releases the neurotransmitter gamma-aminobutyric acid (GABA). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
asymmetric bistratified amacrine cell A bistratified amacrine cell with a medium dendritic field, a flat and sparse dendritic arbor, and post-synaptic terminals at the intersections of S1 and S2, and S3 and S4. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
wavy bistratified amacrine cell A bistratified amacrine cell with a medium dendritic field and post-synaptic terminals in S1-S2, and S4. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
WF1 amacrine cell An amacrine cell with a wide dendritic field, dendrites in S1, and post-synaptic terminals in S1. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
WF2 amacrine cell An amacrine cell with a wide dendritic field, dendrites in S2, and post-synaptic terminals in S1. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
WF3-1 amacrine cell An amacrine cell with a wide dendritic field, dendrites in S3, and post-synaptic terminals in S3. Dendrites of this cell type are straight and minimally branched. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
WF3-2 amacrine cell An amacrine cell with a wild dendritic field, dendrites in S3, and post-synaptic terminals in S3. Dendrites have spikes, cross over each other, and cover a larger volume than dendrties of W3-1 retinal amacrine cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
WF4 amacrine cell An amacrine cell with a wide dendritic field, dendrites in S4, and post-synaptic terminals in S4. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
indoleamine-accumulating amacrine cell An amacrine cell with a wide dendritic field and post-synaptic terminals in S5. This cell type releases the neurotransmitters gamma-aminobutyric acid (GABA) and serotonin. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
monostratified cell A central nervous system neuron that stratifies at one and only one location. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
bistratified cell A neuron that stratifies dendrites at two and only two locations. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
bistratified retinal amacrine cell An amicrine that stratifies dendrites at two and only two locations. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
narrow field retinal amacrine cell An amicrine that has a narrow dendritic field. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
medium field retinal amacrine cell An amicrine that has a medium dendritic field. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
wide field retinal amacrine cell An amicrine that has a wide dendritic field. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
iridoblast A non-terminally differentiated cell that originates from the neural crest and differentiates into an iridophore. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
xanthoblast A non-terminally differentiated cell that differentiates into a xanthophore. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
leucoblast A non-terminally differentiated cell that originates from the neural crest and differentiates into a leucophore. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pigment erythroblast A non-terminally differentiated cell that originates from the neural crest and differentiates into an erythrophore. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cyanoblast A non-terminally differentiated cell that originates from the neural crest and differentiates into a cyanophore. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ionocyte Specialized epithelial cells involved in the maintenance of osmotic homeostasis. They are characterized by abundant mitochondria and ion transporters. In amniotes, they are present in the renal system. In freshwater fish, ionocytes in the skin and gills help maintain osmotic homeostasis by absorbing salt from the external environment. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
macular hair cell An auditory hair cell located in the macula that is sensitive to auditory stimuli. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
renal principal cell A cuboidal epithelial cell of the kidney which regulates sodium and potassium balance. The activity of sodium and potassium channels on the apical membrane of the cell is regulated by aldosterone and vasopressin. In mammals this cell type is located in the renal collecting duct system. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
renal intercalated cell A cuboidal epithelial cell of the kidney that regulates acid/base balance. Synonyms: intercalated cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
renal alpha-intercalated cell A cuboidal epithelial cell of the kidney which secretes acid and reabsorbs base to regulate acid/base balance. Synonyms: type A intercalated cell, type A-IC http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
multiciliated epithelial cell A columnar/cuboidal epithelial cell with multiple motile cilia on its apical surface. These cells facilitate the movement of liquids such as mucus or cerebrospinal fluid across the epithelial surface. Synonyms: multi-ciliated epithelial cell, multiciliated epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
single ciliated epithelial cell A ciliated epithelial cell with a single cilium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
auditory epithelial supporting cell A non-sensory cell that extends from the basement membrane to the apical surface of the auditory epithelium and provides support for auditory hair cells. Synonyms: auditory epithelial support cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
inner phalangeal cell An auditory epithelial support cell that surrounds the nerve fibers and synapses of the auditory inner hair cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ghrelin secreting cell A cell that secretes ghrelin, the peptide hormone that stimulates hunger. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pancreatic epsilon cell Ghrelin secreting cells found in the endocrine pancreas. Synonyms: pancreatic E cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lymphangioblast Lymphatic progenitor cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesenchymal lymphangioblast Mesenchymal derived lymphatic progenitor cells that give rise to the superficial lymphatics. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
vascular lymphangioblast Lymphatic progenitor cells, derived from the veins, that give rise to lymphatic endothelial cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hepatoblast Multi fate stem cell that gives rise to both hepatocytes and cholangiocytes as descendants. The term often refers to fetal precursors of hepatocytes (differently from 'hepatic stem cell', usually applied to the self-renewing pool of hepatocyte precursors in the adult liver). Hepatoblasts may also be endogenous, as some stem cells found in the liver come from the bone marrow via blood circulation. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
preameloblast Skeletogenic cell that has the potential to develop into an ameloblast. Located in the inner enamel epithelium, these cells elongate, their nuclei shift distally (away from the dental papilla), and their cytoplasm becomes filled with organelles needed for synthesis and secretion of enamel proteins. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
skeletogenic cell Cell that has the potential to form a skeletal cell type (e.g. cells in periosteum, cells in marrow) and produce extracellular matrix (often mineralized) and skeletal tissue (often mineralized). Synonyms: scleroblast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
precementoblast Skeletogenic cell that has the potential to develop into a cementoblast. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
preodontoblast Skeletogenic cell that has the potential to form an odontoblast, deposits predentine, and arises from a cranial neural crest cell. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
premigratory neural crest cell Cell that is part of the neural crest region of the neuroepithelium, prior to migration. Note that not all premigratory neural crest cells may become migratory neural crest cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
notochordal cell Cell that is part of the notochord. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
chordamesodermal cell Mesodermal cell that is axially located and gives rise to the cells of the notochord. Synonyms: axial mesodermal cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
notochordal sheath cell Notochordal cell that is part of the outer epithelium of the notochord and surrounds the vacuolated notochord cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
notochordal vacuole cell Notochordal cell that is inner portion of the notochord and becomes vacuolated as development proceeds. Synonyms: chordablast, chordoblast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
prechondroblast Skeletogenic cell that has the potential to develop into a chondroblast; and arises from neural crest, meseosdermal and notochordal and connective tissue cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
preosteoblast Skeletogenic cell that has the potential to transform into an osteoblast, and develops from neural crest or mesodermal cells. Synonyms: osteoprogenitor cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
non-terminally differentiated odontoblast Odontoblast that non-terminally differentiated, located in the odontogenic papilla and dentine tissue, and transforms from a odontoblast cell. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
terminally differentiated odontoblast Odontoblast that is terminally differentiated and derived from an odontogenic papilla and associated with dentine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
adaxial cell Muscle precursor cell that is adjacent to the notochord and part of the presomitic mesoderm. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Stiftchenzellen An epidermal cell with apical microvilli or a single apical projection have synaptic associations with nerve fibres in the epidermis. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epidermal ciliary cell Ciliated cell of the embryonic epidermis and functions in embryonic movements. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epidermal mucus secreting cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
bottle cell Characteristic early embryonic cell with a bottle or flask shape that is first to migrate inwards at the blastopore during gastrulation in amphibians. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
alarm substance cell Secretory cell that produces a chemical mixture that triggers antipredator behavior. The substance is released only upon disruption of the epidermis. [Behavior of teleost fishes, second edition, edited by Pitcher, 1992] Synonyms: alarm substance secreting cell, club cell (zebrafish) http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
micropylar cell A specialized pore forming cell of the follicle, located adjacent to the animal pole of the oocyte. The micropylar cell makes the single micropyle (pore) through the chorion through which the sperm fertilizes the egg. Synonyms: plug cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
flask cell Epidermal cell rich in mitochondria. In amphibians, appears during metamorphosis. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
non-striated muscle cell Any muscle cell in which the fibers are not organised into sarcomeres. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hematopoietic precursor cell Any hematopoietic cell that is a precursor of some other hematopoietic cell type. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
skeletal muscle fiber A transversely striated, synctial cell of skeletal muscle. It is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
somatic muscle myotube A myotube that is part of some somatic muscle. Examples include arthropod somatic muscle cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
somatic muscle cell A muscle cell that is part of some somatic muscle. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
obliquely striated somatic muscle cell A somatic muscle cell that is obliquely striated and mononucleated. Examples include the somatic muscles of nematodes. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
muscle founder cell A myoblast that detemines the properties (size, shape and attachment to the epidermis) of a `somatic muscle myotube` (CL:0008003) . It develops into a somatic muscle myotube via fusion with `fusion component myoblasts` (CL:0000621). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
visceral muscle cell A muscle cell that is part of some visceral muscle. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
striated visceral muscle cell A visceral muscle cell that is striated. Examples include the visceral muscle cells of arhtropods. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
transversely striated visceral muscle cell A visceral muscle that is transversely striated. Examples include the visceral muscle cells of arthropods. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
skeletal muscle satellite stem cell A skeletal muscle satellite cell that divides by stem cell division. A proportion of this population undergoes symmetric stem cell division, producing two skeletal muscle satellite stem cells. The rest undergo asymmetric stem cell division - retaining their identity while budding off a daughter cell that differentiates into an adult skeletal muscle myoblast. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
quiescent skeletal muscle satellite cell A skeletal muscle satellite cell that is mitotically quiescent. These cells are wedge shaped and have a large nuclear to cytoplasmic ratio with few organelles, a small nucleus and condensed interphase chromatin. Satellite cells typically remain in this state until activated following muscle damage. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
activated skeletal muscle satellite cell A skeletal muscle satellite cell that has become mitotically active - typically following muscle damage. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
adult skeletal muscle myoblast A skeletal muscle myoblast that is part of a skeletal mucle. These cells are formed following acivation and division of skeletal muscle satellite cells. They form a transient population that is lost when they fuse to form skeletal muscle fibers. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
somatic muscle myoblast A myoblast that is commited to developing into a somatic muscle. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesenchymal cell A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration. Synonyms: mesenchyme cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
skeletal muscle satellite myogenic cell A skeletal muscle satellite cell that undergoes symmetric division to produce two adult skeleltal muscle myoblasts. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endocardial cushion cell A mesenchymal cell of the endocardial cushion. These cells develop via an epithelial to mesenchymal transition when endocardial cells break cell-to-cell contacts and migrate into the cardiac jelly. Cells from this population form the heart septa and valves. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pancreatic endocrine cell An endocrine cell that is part of the pancreas. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
decidual pericyte A pericyte of the decidual vasculature. Synonyms: decidual perivascular cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mural cell Mural cells are pericytes and the vascular smooth muscle cells (vSMCs) of the microcirculation. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
microcirculation associated smooth muscle cell Any vascular associated smooth muscle cell that is part of some microcirculatory vessel. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
extravillous trophoblast A trophoblast cell that is not part of a placental villous. Synonyms: EVT, extravillous cytotrophloblast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
squamous endothelial cell of venule An endothelial cell of the venule that is squamous shaped. This is in contrast to the cubodial shape of high endothelial venule cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesothelial cell of intestine A mesothelial cell that is part of the intestinal serosa. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tanycyte of subfornical organ A tanycyte of the subfornical organ (SFO). These cells extend long and slender fibers extending from their cell bodies in the ependyma toward fenestrated capillaries associated with the SFO, where they form a dense network surrounding these capillaries. Synonyms: tanycyte-like cell of subfornical organ http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tanycyte of area postrema A tanycyte of the area postrema (AP). These cells extend long and slender fibers extending from their cell bodies in the ependyma toward fenestrated capillaries associated with the AP, where they form a dense network surrounding these capillaries. Synonyms: tanycyte-like cell of area postrema http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tanycyte of subcommissural organ A tanycyte of the subcommisural organ (SCO). These cells extend long and slender fibers extending from their cell bodies in the ependyma toward fenestrated capillaries associated with the SCO, where they form a dense network surrounding these capillaries. Synonyms: tanycyte-like cell of subcommissural organ http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
extrafusal muscle fiber A skeletal muscle fiber that is innervated by alpha motor neuron and generates tension by contracting, thereby allowing for skeletal movement. These fibers make up the large mass of skeletal muscle tissue and are attached to bones by tendons. Synonyms: myofibra extrafusalis http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
intrafusal muscle fiber A skeletal muscle fiber that is part of a muscle spindle. These are specialized muscle fibers that serve as proprioceptors, detecting the amount and rate of change in length of a muscle. They are innervated by both sensory neurons and motor neurons (gamma and beta motorneurons, collectively referred to as fusimotor neurons). Synonyms: myofibra intrafusalis http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Betz cell A giant pyramidal neuron with a soma in layer Vb of the primary motor cortex that sends its axons down the spinal cord via the corticospinal tract, either synapsing directly with alpha motor neurons, or targeting interneurons in the spinal cord. In humans, Betz cells are the largest known in the central nervous system. Synonyms: pyramidal cell of Betz http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
circumventricular organ capillary endothelial cell A capillary endothelial cell that is part of the circumventricular organs (CVOs), characterized by fenestrations that facilitate selective permeability to molecules, distinguishing it from the non-fenestrated endothelial cells of the blood-brain barrier. This cell is integral to the unique vascular structure of CVOs, which lack a traditional blood-brain barrier. It enables bidirectional exchange of polar molecules between blood and neural tissue, supporting neuroendocrine signaling, fluid balance, and immune responses. It is marked by the expression of PLVAP, a component of the fenestral diaphragm, in both rodents and humans. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
respiratory tract secretory epithelial cell A secretory epithelial cell of the respiratory tract epithelium. These cells have an endodermal origin. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
inflammatory cell Any cell participating in the inflammatory response to a foreign substance, e.g. neutrophil, macrophage. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
retinal cell Any cell in the retina, the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
salivary gland cell Any cell in a salivary gland. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
enteroendocrine cell of small intestine An enteroendocrine cell that is located in the small intestine. Synonyms: small intestine enteroendocrine cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
gastrointestinal tract (lamina propria) macrophage of small intestine A macrophage which is resident in the lamina propria of the small intestine. Synonyms: small intestine lamina propria resident macrophage http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
gastrointestinal tract (lamina propria) macrophage of large intestine A macrophage which is resident in the lamina propria of the large intestine. Synonyms: large intestine lamina propria resident macrophage http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
paneth cell of colon A paneth cell that is located in the epithelium of the colon. Synonyms: paneth cell of epithelium of colon, paneth-like cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
transit amplifying cell Transit-amplifying cells (TACs) are an undifferentiated population in transition between stem cells and differentiated cells. Synonyms: transient amplifying cell, transit amplifying progenitor cell, transit-amplifying cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
transit amplifying cell of colon A rapidly proliferating population of cells that differentiate from stem cells of the intestinal crypt of the colon. Stem cells located in the crypts of Lieberkühn give rise to proliferating progenitor or transit amplifying cells that differentiate into the four major epithelial cell types. These include columnar absorptive cells or enterocytes, mucous secreting goblet cells, enteroendocrine cells and paneth cells. Synonyms: colon transit amplifying cell, transient amplifying cell of colon, transient amplifying cell of crypt of Lieberkuhn of colon, transit amplifying cell of crypt of Lieberkuhn of colon, transit-amplifying cell of colon http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
transit amplifying cell of small intestine A rapidly proliferating population of cells that differentiate from stem cells of the intestinal crypt of the small intestine. Stem cells located in the crypts of Lieberkühn give rise to proliferating progenitor or transit amplifying cells that differentiate into the four major epithelial cell types. These include columnar absorptive cells or enterocytes, mucous secreting goblet cells, enteroendocrine cells and paneth cells. Synonyms: small intestine transit amplifying cell, transient amplifying cell of crypt of Lieberkuhn of small intestine, transient amplifying cell of small intestine, transit amplifying cell of crypt of Lieberkuhn of small intestine, transit-amplifying cell of small intestine http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fetal hepatobiliary progenitor cell A progenitor cell with hepatic and biliary lineage potential, identified in mouse and human, and anatomically restricted to the ductal plate of fetal liver. Synonyms: HHyP cell, fetal hepatobiliary hybrid progenitor cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Peyer's patch lymphocyte A lymphocyte that is part of a Peyer's patch. These cells have a major role in driving the immune response to antigens sampled from the intestinal lumen, and in regulating the formation of follicle-associated epithelium and M cells in Peyer's patches by converting intestitial enterocytes into M cells. Synonyms: Peyer's patch resident lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Peyer's patch follicular dendritic cell A follicular dendritic cell located in the Peyer's patch. These cells from a meshwork in which Peyer's patch B cells reside. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
intestinal crypt stem cell of large intestine An intestinal stem cell that is located in the large intestine crypt of Liberkuhn. These stem cells reside at the bottom of crypts in the large intestine and are highly proliferative. They either differentiate into transit amplifying cells or self-renew to form new stem cells. Synonyms: stem cell of large intestine crypt of Lieberkuhn http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
intestinal crypt stem cell of small intestine An intestinal stem cell that is located in the small intestine crypt of Liberkuhn. These stem cells reside at the bottom of crypts in the small intestine and are highly proliferative. They either differentiate into transit amplifying cells or self-renew to form new stem cells. Synonyms: stem cell of small intestine crypt of Lieberkuhn http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lymphocyte of large intestine lamina propria A lymphocyte that resides in the lamina propria of the large intestine. Synonyms: lamina propria lymphocyte of large intestine http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
nephrogenic zone cell A kidney cortical cell that is part of the nephrogenic zone. Synonyms: cortical nephrogenic niche cell, cortical nephrogenic zone cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tuft cell of appendix An intestinal tuft cell that is a part of a vermiform appendix. Synonyms: appendix tuft cell, tuft cell of appendix vermiformis, tuft cell of vermiform appendix http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stromal cell of lamina propria of large intestine A stromal cell found in the lamina propria of the large intestine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stromal cell of lamina propria of small intestine A stromal cell found in the lamina propria of the small intestine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
small intestine Peyer's patch T cell A T cell which resides in the Peyer's patch of the small intestine. Synonyms: T cell of Peyer's patch of small intestine, T cell of small intestine Peyer's patch http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesothelial cell of small intestine A mesothelial cell that is part of the small intestine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesothelial cell of colon A mesothelial cell that is part of the colon. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
enterocyte of appendix An enterocyte that is a part of a vermiform appendix. Synonyms: appendix enterocyte, enterocyte of appendix vermiformis, enterocyte of vermiform appendix http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
transit amplifying cell of appendix A transit amplifying cell that is part of a crypt of Lieberkuhn of large intestine. Synonyms: appendix transit amplifying cell, transit amplifying cell of appendix vermiformis, transit amplifying cell of vermiform appendix http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
intestinal crypt stem cell of appendix An intestinal crypt stem cell that is located in the vermiform appendix. These stem cells reside at the bottom of crypts in the appendix and are highly proliferative. They either differentiate into transit amplifying cells or self-renew to form new stem cells. Synonyms: appendix intestinal crypt stem cell, intestinal crypt stem cell of appendix vermiformis, intestinal crypt stem cell of vermiform appendix, stem cell of intestinal crypt of Lieberkuhn of appendix, stem cell of intestinal crypt of Lieberkuhn of appendix vermiformis http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesothelial cell of appendix A mesothelial cell that is located in a vermiform appendix. Synonyms: appendix mesothelial cell, mesothelial cell of appendix vermiformis, mesothelial cell of vermiform appendix http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
enteroendocrine cell of appendix An intestinal enteroendocrine cell that is located in a vermiform appendix. Synonyms: appendix enteroendocrine cell, enteroendocrine cell of appendix vermiformis, enteroendocrine cell of vermiform appendix http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
T cell of appendix A T cell that is located in a vermiform appendix. Synonyms: T cell of appendix vermiformis, T cell of vermiform appendix, appendix T cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
B cell of appendix A B cell that is located in a vermiform appendix. Synonyms: B cell of appendix vermiformis, B cell of vermiform appendix, appendix B cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
plasma cell of appendix A plasma cell that is located in a vermiform appendix. Synonyms: appendix plasma cell, plasma cell of appendix vermiformis, plasma cell of vermiform appendix http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
dendritic cell of appendix A dendritic cell that is located in a vermiform appendix. Synonyms: appendix dendritic cell, dendritic cell of appendix vermiformis, dendritic cell of vermiform appendix http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stromal cell of lamina propria of vermiform appendix A stromal cell found in the lamina propria of the vermiform appendix. Synonyms: stromal cell of appendix lamina propria, stromal cell of lamina propria of appendix vermiformis http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
appendix macrophage A macrophage located in the vermiform appendix. Synonyms: macrophage of appendix, macrophage of appendix vermiformis, macrophage of vermiform appendix http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lymph node mantle zone B cell A B lymphocyte that resides in the mantle zone of the lymph node germinal center. These are generally IgM and IgD positive activated B cells that form a 'corona' around the germinal center and are part of the establishment of a secondary lymphatic follicule. Synonyms: mantle zone B cell of lymph node http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
colon macrophage A macrophage that is located in the colon. Synonyms: macrophage of colon http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
colon goblet cell A goblet cell that is located in the colon. Synonyms: goblet cell of colon http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stromal cell of lamina propria of colon A stromal cell found in the lamina propria of the colon. Synonyms: stromal cell of colon lamina propria http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tuft cell of colon A tuft cell that is part of the colonic epithelium, primarily adapted for microbial sensing in the dense colonic microbiota. Unlike its small intestinal counterpart, it does not participate in parasite-driven tuft cell–ILC2 circuits. Instead, it detects bacterial metabolites via taste-signaling pathways (Strine and Craig, 2022). The colonic tuft cell plays a key role in epithelial repair, modulates inflammatory responses through IL-25 secretion, and contributes to intestinal homeostasis by balancing microbiome interactions (Sebastian et al., 2021). Synonyms: colon tuft cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
enteroendocrine cell of colon An enteroendocrine cell that is located in the colon. Synonyms: colon enteroendocrine cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
intestinal crypt stem cell of colon An intestinal crypt stem cell that is located in the crypt of Lieberkuhn of colon. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lymphocyte of small intestine lamina propria A lymphocyte that resides in the lamina propria of the small intestine. Lamina propria leukocytes and intraepithelial lymphocytes are the effector compartments of the gut mucosal immune system. Lymphocytes circulate through gut associated lymphoid tissues until recruitment by intestinal antigens. They are involved in the gut immune response. Synonyms: gastrointestinal tract (lamina propria) lymphocyte of small intestine, lamina propria lymphocyte of small intestine, small intestine lamina propria lymphocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
B cell of medullary sinus of lymph node A B cell found in the lymph node medullary sinus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
T cell of medullary sinus of lymph node A T cell found in the lymph node medullary sinus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
macrophage of medullary sinus of lymph node A macrophage found in the medullary sinus of the lymph node. Synonyms: lymph node medullary sinus macrophage http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
anorectum macrophage A macrophage that is located in the anorectum. Synonyms: macrophage of anorectum http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle cell of high endothelial venule of lymph node A layer of smooth muscle cells that forms the outer layer of the high endothelial venule of lymph node and pumps to allow flow of lymph fluid carrying lymphocytes. Synonyms: high endothelial venule of lymph node smooth muscle cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
B cell of anorectum A B cell that is located in the anorectum. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
T cell of anorectum A T cell that is located in the anorectum. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle cell of anorectum A smooth muscle cell that is located in the anorectum. Synonyms: anorectum smooth muscle cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stromal cell of anorectum lamina propria A stromal cell found in the lamina propria of the anorectum. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
microfold cell of epithelium proper of anorectum A microfold cell (M cell) that is part of the anorectum. Synonyms: M cell of anorectum http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
paneth cell of anorectum A paneth cell that is located in the anorectum. Synonyms: anorectum paneth cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
transit amplifying cell of anorectum A transit amplifying cell that is located in the anorectum. Synonyms: anorectum transit amplifying cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
anorectum goblet cell A goblet cell that is located in the anorectum. Synonyms: goblet cell of anorectum http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
enterocyte of anorectum An enterocyte that is located in the anorectum. Synonyms: anorectum enterocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
plasma cell of medullary sinus of lymph node A plasma cell that is located in the medullary sinus of the lymph node. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
marginal zone B cell of lymph node A mature B cell located in the marginal zone of the lymph node. Synonyms: lymph node marginal zone B cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
intestinal crypt stem cell of anorectum An intestinal crypt stem cell that is located in the anorectum. Synonyms: anorectum intestinal crypt stem cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
germinal center T cell A specialized type of CD4 positive T cell, the follicular helper T cell (TFH cell), that upregulates CXCR5 expression to enable its follicular localization. These specialised T cells reside in the germinal center of the lymph node. Synonyms: T follicular helper cell of germinal center of lymph node, T follicular helper cell of lymph node germinal center, lymph node germinal center T follicular helper cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
enteroendocrine cell of anorectum An enteroendocrine cell that is located in the anorectum. Synonyms: anorectum enteroendocrine cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lymph node paracortex T cell A T cell located in the lymph node paracortex, where macrophages and dendritic cells present antigenic peptides to these naïve T cells, stimulating them to become activated helper T cells or cytotoxic T lymphocytes. Synonyms: T cell of lymph node paracortex http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tuft cell of anorectum An intestinal tuft cell that is located in the anorectum. Synonyms: anorectum tuft cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stratified squamous epithelial cell of anal canal A stratified squamous epithelial cell that is part of the anal canal. Synonyms: anal canal stratified squamous epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
vacuolated fetal-type enterocyte An enterocyte found in the small intestine of newborn mammals and characterized by the presence of an apical canalicular system (ACS) leading to production of large vacuoles, important for colostral macromolecule uptake. After birth, the vacuolated fetal-type enterocytes are replaced with enterocytes lacking an ACS. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD8aa(I) thymocyte An unconventional T lymphocyte population within the thymic medulla that is potentially a thymic resident population. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD8aa(II) thymocyte An unconventional T lymphocyte population within the thymic medulla that expresses both alpha/beta and gamma/delta T cell signatures. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
corticomedullary thymic epithelial cell A thymic epithelial cell located at the corticomedullary junction. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
medullary thymic epithelial cell type 1 A thymic medullary epithelial cell considered to be a pre-AIRE mTEC population. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
medullary thymic epithelial cell type 2 A thymic medullary epithelial cell that expresses AIRE or other canonical markers of mature mTECs like Fezf2. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
medullary thymic epithelial cell type 3 A thymic medullary epithelial cell considered to be a post-AIRE cell. This group of AIRE-mTECs is heterogeneous and also includes mTECs within Hassall's Corpuscles. Synonyms: corneocyte-like mTECs, corneocyte-like medullary thymic epithelial cell, post-Aire cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
medullary thymic epithelial cell type 4 A thymic medullary epithelial cell that expresses typical tuft cell markers instead of classical mTEC or cTEC markers. This population has a bulbous-like structure. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myo-medullary thymic epithelial cell A thymic medullary epithelial cell that expresses muscle-specific biomarkers. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
subcapsular thymic epithelial cell A thymic epithelial cell located within the subcapsular region of the thymus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
thymic fibroblast type 1 A fibroblast located in the thymic capsule. Synonyms: thymic capsular fibroblast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
thymic fibroblast type 2 A fibroblast located between thymic lobules. Synonyms: thymic interlobular fibroblast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tuft cell of small intestine A tuft cell located in the small intestine. Synonyms: brush cell of epithelium of small intestine, brush cell of epithelium proper of small intestine, brush cell of small intestine, tuft cell of epithelium of small intestine http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
specified double negative thymocyte (Homo sapiens) The human equivalent of a DN2 thymocyte; typically contains two phases, in the latter of which these thymocytes begin the process of beta selection. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
committed double negative thymocyte (Homo sapiens) The human equivalent of a DN3 thymocyte; these thymocytes finish the process of beta selection. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
rearranging double negative thymocyte (Homo sapiens) The human equivalent of a DN4 thymocyte. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
glandular epithelial cell of endometrium An epithelial cell that is part of an endometrium glandular epithelium. Synonyms: endometrial glandular epithelial cell, epithelial cell of endometrial gland http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
colony forming unit – Hill cell An adult endothelial progenitor cell characterised in vivo by homing to ischemic sites and paracrine support of angiogenesis. They may form discrete colonies. Synonyms: CFU-Hill http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endothelial cell of respiratory system lymphatic vessel An endothelial cell that is part of a respiratory system lymphatic vessel. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fused extravillous trophoblast An extravillous trophoblast that is polynuclear. Synonyms: fused EVT http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
circulating angiogenic cell An adult endothelial progenitor cell characterised in vivo by homing to ischemic sites and paracrine support of angiogenesis. These cells do not form colonies. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lung pericyte A pericyte cell that is part of a lung. Synonyms: lung pericyte cell, pulmonary pericyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endothelial colony forming cell An adult endothelial progenitor cell that is resident of adult vasculature and capable of differentiating to regenerate endothelial cell populations. Endothelial colony forming cells are characterised in vivo by clonal proliferative status, de novo vessel formation, homing to ischemic sites and paracrine support of angiogenesis. These cells are phenotypically similar to endothelial cells. Synonyms: ECFC http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Leydig stem cell A stem cell found in the interstitial compartment of the neonatal testis; it is capable of self-renewal as well as differentiation into steroidogenic cells (adult Leydig cells). Intermediate stages of development include progenitor Leydig cells and immature Leydig cells. Synonyms: stem Leydig cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endothelial cell of placenta An endothelial cell that is part of a placenta. Synonyms: placental endothelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle cell of placenta A smooth muscle cell that is part of a placenta. Synonyms: placental smooth muscle cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endothelial cell of hepatic portal vein An endothelial cell that is part of a hepatic portal vein. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endothelial cell of uterus An endothelial cell that is part of a uterus. Synonyms: uterine endothelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
esophagus non-keratinized squamous epithelial cell Any cell that is part of the esophageal non-keratinized stratified squamous epithelium. In humans, the esophagus, which requires flexibility to accommodate swallowing of a bolus, is covered with a non-keratinized epithelium. Synonyms: esophageal non-keratinized squamous epithelial cell, esophageal nonkeratinized squamous epithelial cell, esophagus non-keratinizing squamous epithelial cell, esophagus nonkeratinizing squamous epithelial cell, non-keratinized squamous epithelial cell of esophagus, non-keratinizing squamous epithelial cell of esophagus, nonkeratinized squamous epithelial cell of esophagus, nonkeratinizing squamous epithelial cell of esophagus http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
embryonic skeletal muscle fiber A skeletal muscle fiber found in an embryo. In mammalian embryos, skeletal muscle expresses myosin heavy chain-embryonic (MyHC-emb, encoded by the MYH3 gene), which regulates skeletal muscle development. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fetal and neonatal skeletal muscle fiber A skeletal muscle fiber found at the fetal and neonatal stages. In mammalian fetuses and neonates, skeletal muscle expresses myosin heavy chain-neonatal (MyHC-neo, encoded by the MYH8 gene). This expression disappears shortly after birth and is replaced by expression of adult heavy chain myosins. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibro/adipogenic progenitor cell A progenitor cell that is a tissue-resident mesenchymal cell, important for skeletal muscle regeneration, and able to differentiate into both adipocytes or fibroblasts. Synonyms: fibro/adipogenic progenitor http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hepatic portal fibroblast A fibroblast located in the portal triad. Hepatic portal fibroblast are a non-parenchymal cell population located adjacent to bile duct epithelia in liver and are distinct from stellate cells. They differentiate into fibrogenic myofibroblasts during chronic injury states producing high levels of collagen. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblastic reticular cell A reticular cell involved in directing B cells and T cells to specific regions within a tissue. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lymph node fibroblastic reticular cell A specialized, fibroblastic reticular cell of mesenchymal origin found in lymph nodes. In human, it expresses several markers common to myofibroblasts (desmin, vimentin, CD73, CD90, α-smooth muscle actin (αSMA)), and can be differentiated from endothelial cells by its lack of CD31 expression. These cells are critical for the overall organization and function of the lymph node. Lymph node fibroblastic reticular cells (FRCs) can be further classified based on their location, function, and unique marker expression. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lymph node marginal reticular cell A fibroblastic reticular cell found in the lymph node subcapsular sinus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
B cell zone reticular cell A fibroblastic reticular cell found in the lymph node germinal center dark zone (B cell zone). Synonyms: lymph node germinal center dark zone fibroblastic reticular cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
T cell zone reticular cell A fibroblastic reticular cell found in the lymph node T cell domain. Synonyms: lymph node T cell domain fibroblastic reticular cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
medullary reticular cell A specialized fibroblast found in the medulla of lymph node. Synonyms: lymph node medullary reticular cell, medullary reticular cell of lymph node http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lymphatic endothelial cell of subcapsular sinus ceiling A lymphatic endothelial cell located in the subcapsular sinus ceiling of a lymph node. In human, it's characterized by a unique marker expression (NT5e+ and Caveolin-1+). Synonyms: lymphatic endothelial cell of subcapsular sinus ceiling of lymph node http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lymphatic endothelial cell of subcapsular sinus floor A lymphatic endothelial cell located in the subcapsular sinus floor of a lymph node. In human, it's characterized by a unique marker expression (TNFRSF9+). Synonyms: lymphatic endothelial cell of subcapsular sinus floor of lymph node http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lymphatic endothelial cell of trabecula A lymphatic endothelial cell located in a lymph node trabecula. Synonyms: lymphatic endothelial cell of lymph node trabecula, lymphatic endothelial cell of trabeculae http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lymphatic endothelial cell of medulla ceiling A lymphatic endothelial cell located in the ceiling part of a lymph node medulla. Synonyms: lymphatic endothelial cell of lymph node medulla ceiling http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
centrocyte A germinal center B cell found in a lymph node germinal center light zone. Synonyms: lymph node centrocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
centroblast A germinal center B cell found in a lymph node germinal center dark zone. Synonyms: lymph node centroblast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
T follicular regulatory cell A regulatory T cell present in the B cell follicles and germinal centers of lymphoid tissues. In humans, it is CXCR5+. Synonyms: follicular regulatory T cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
monocytoid B cell A B cell found in the perisinusoidal area of a lymph node. In humans, monocytoid B cells are a morphologically distinct B cell population (oval nuclei, abundant cytoplasm, monocyte-like appearance), share many similarities with marginal zone B cells including marker expression, and are increased in disease settings. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lymph node lymphatic vessel endothelial cell An endothelial cell located in a lymph node lymphatic vessel. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
progenitor cell of mammary luminal epithelium A progenitor cell with the potential to differentiate into luminal epithelial cells of mammary glands. In mouse, CD61 and c-kit were found to be coexpressed by the majority of, but not all, committed luminal progenitor cells. Synonyms: progenitor cell of luminal mammary epithelium http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
keratinized cell of hair follicle A differentiating matrix keratinocyte that has initiated terminal differentiation and keratin synthesis. This cell undergoes a characteristic change while migrating upward from the hair follicle bulb, representing a committed progenitor cell destined to form the hair medulla, cortex and hair root sheath. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stromal cell of bone marrow A stromal cell that is part_of a bone marrow. Synonyms: bone marrow stromal cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of umbilical artery An epithelial cell that is part_of a umbilical artery. Synonyms: umbilical artery epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mononuclear cell of bone marrow A mononuclear cell that is part_of a bone marrow. Synonyms: bone marrow mononuclear cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
atrioventricular bundle cell A specialized cardiomyocyte that transmit signals from the AV node to the cardiac Purkinje fibers. Synonyms: AV bundle cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cardiac blood vessel endothelial cell Any blood vessel endothelial cell that is part of some heart. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
His-Purkinje system cell Any cell that is part of some His-Purkinje system. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cardiac endothelial cell Any endothelial cell that is part of some heart. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
camera-type eye photoreceptor cell Any photoreceptor cell that is part of some camera-type eye. Synonyms: camera type eye photoreceptor cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cerebellar stellate cell A GABAergic interneuron that is located in the molecular layer of the cerebellum. This cell receives excitatory inputs primarily from parallel fibers and plays a crucial role in feed-forward inhibition by suppressing the activity of Purkinje cells and modulating the output of the cerebellar cortex. The stellate cell is part of the local circuitry that contributes to the fine-tuning of motor coordination and a regulator of cerebellar blood flow via neurovascular coupling. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type I pinealocyte Synonyms: light pinealocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type II pinealocyte Synonyms: dark pinealocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
coronet cell A highly specialized cell type exclusive to and forming neuroepithelium of the Saccus vasculosus, covering the caudal diverticulum of the infundibular recess. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
collar cell A cell with a flagellum surrounded by a collar of microvilli. The motion of the flagellum draws water past the microvilli, serving either a feeding or sensory function. Collar cells are found in multiple animals, including sponges, echinoderms, and cnidarians. They are also found outside animals in the choanoflagellates. Although collar cells are superficially similar, their cytoskeletal structure and functional biology are different in different groups of organisms. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
zygote A zygote in a plant or an animal. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cardiac glial cell Any glial cell that is part of some heart. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cardiac myoblast Any myoblast that develops into some cardiac muscle cell. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lens fiber cell A vetebrate lens cell that is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye. Synonyms: lens fibre cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Lugaro cell A cerebellar interneuron characterized by a spindle-shaped or triangular soma, parasagittally oriented and located at the border between the granular layer and the Purkinje cell layer. The Lugaro cell extends dendrites predominantly in the parasagittal plane, forming synaptic interactions with basket, stellate, and Golgi cells. Its axonal projections extend upward into the molecular layer, where they form a parasagittal plexus and emit long transverse collaterals that run parallel to the long axis of the cerebellar folia. The Lugaro cell is capable of co-releasing GABA and glycine, as evidenced by the expression of glutamate decarboxylase (GAD65/67) and the glycine transporter GlyT2. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
paraxial cell A cell in the area of mesoderm in the neurulating embryo that flanks and forms simultaneously with the neural tube. The cells of this region give rise to somites. Synonyms: paraxial mesoderm cell, somitic mesoderm cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lateral mesodermal cell A cell derived from the mesoderm that is found at the periphery of the embryo. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
intermediate mesodermal cell A cell derived from the mesoderm that is located between the paraxial mesoderm and the lateral plate. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
neural crest cell A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
motile sperm cell A sperm cell that is cabaple of motion (motility). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
non-motile sperm cell A sperm cell that is not cabaple of motion (motility). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
amoeboid sperm cell A motile sperm cell that contain no F-actin, and their motility is powered by a dynamic filament system. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
flagellated sperm cell A motile sperm cell that contains a slender threadlike microscopic appendage that enables motion. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
vagal neural crest cell Cell that is part of the vagal neural crest population. The vagal neural crest arises from the axial level of somites 1-7 and has been described as a hybrid between the head and the trunk populations. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lymphoid tissue–inducer cell A group 3 innate lymphoid cell that express ROR gamma t and IL-7R alpha in the absence of lineage markers (e.g. CD3, CD19, B220, CD11c, Gr-1), with the functional ability to interact with mesenchymal cells through lymphotoxin and tumor necrosis factor. Lymphoid tissue-inducer cells are key to the development of lymph nodes and Peyer’s patches. Synonyms: LTi, lymphoid tissue inducer cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesothelial cell of epicardium A mesothelial cell that is part of the epicardium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
neural progenitor cell An undifferentiated cell derived from a neural stem cell, with a limited capacity to self-renew (Dibajnia and Morshead, 2013) and the ability to generate multiple types of lineage-restricted progenitors, contributing to the formation of neurons, astrocytes, and oligodendrocytes. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of upper back skin A fibroblast that is part of upper back skin. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of skin of back A fibroblast that is part of skin of back. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD25+ mast cell A mast cell that is CD25+. Synonyms: CD25+ neoplastic mast cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
double negative T regulatory cell A double negative thymocyte that is CD3-positive, CD4-negative, CD8-negative, that that are present in the periphery in very low numbers and predominantly produce INF-gamma, TNF-alpha, and a low amount of TGF-beta, but not IL-2, IL-4, IL-10 or IL-13 upon activation. Synonyms: CD4-negative, CD8-negative, alpha-beta regulatory T cells, DN Treg, double-negative alpha-beta regulatory T cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
exhausted T cell An effector T cell that displays impaired effector functions (e.g., rapid production of effector cytokines, cytotoxicity) and has limited proliferative potential. Synonyms: Tex cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
progenitor cell A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
skeletal muscle fibroblast Any fibroblast that is part of skeletal muscle tissue. Synonyms: skeleton muscle fibroblast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
olfactory ensheathing cell A neural-crest derived glial cell that supports the growth and survival of primary olfactory neuroons from the neuroepithelium in the nasal cavity to the brain by encasing large bundles of numerous unmyelinated axons. Synonyms: OEC http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
dermal microvascular endothelial cell Any microvascular endothelial cell that is part of the dermis. Synonyms: DMEC cell, dermal microvascular endothelium cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
monocyte-derived dendritic cell A dendritic cell that develops from a monocyte. Synonyms: MDDC cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lysosome-rich enterocyte An enterocyte that possesses a large supranuclear vacuolar system that preferentially internalizes dietary protein via receptor-mediated and fluid-phase endocytosis for intracellular digestion and trans-cellular transport. In zebrafish these cells are located in the posterior region of the mid intestine throughout life. In mammals they are found in the ileum pre-weaning and later are replaced by mature enterocytes. Synonyms: LRE http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
chorionic trophoblast cell Cells of the uterine chorion that acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
interplexiform cell A type of interneuron in the retinal inner nuclear layer which carries information from the inner plexiform layer and the outer plexiform layer. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
dopamanergic interplexiform cell A type of interneuron in the retinal inner nuclear layer which carries information from the inner plexiform layer and the outer plexiform layer, using dopamine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
GABAnergic interplexiform cell A type of interneuron in the retinal inner nuclear layer which carries information from the inner plexiform layer and the outer plexiform layer using GABA. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
colon epithelial cell Epithelial cell that is part of the colon epithelium. Synonyms: colonic epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
segmented neutrophil of bone marrow A segmented neutrophilic cell of the bone marrow reserve pool that expresses CD11b (integrin alpha-M) and high levels of CD16 (low affinity immunoglobulin gamma Fc region receptor III) on its cell surface. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
precursor cell A cell that, by division or terminal differentiation, can give rise to other cell types. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
astrocyte of the forebrain An astrocyte of the forebrain. Synonyms: forebrain astrocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
forebrain radial glial cell Any radial glial cell that is part of some forebrain. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pulmonary ionocyte An ionocyte that is part of the lung epithelium. The cells from this type are major sources of the CFTR protein in human and mice. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
splanchnic mesodermal cell A mesodermal cell that is part of the splanchnic layer of lateral plate mesoderm. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of prostatic urethra An epithelial cell that is part of the prostatic urethra. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
telocyte A supportive cell with a small, oval-shaped body and one to five telopodes. Telopodes are cytoplasmic protrusions from tens to hundreds of micrometers long and mostly below 0.2 microns of caliber. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lymphoblast A lymphocyte that has gotten larger after being stimulated by an antigen. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
B-lymphoblast A lymphocyte of B lineage that has gotten larger after being stimulated by an antigen. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Axl+ dendritic cell, human A human dendritic cell that expresses the AXL and SIGLEC6 genes. Synonyms: AS DC, human http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hillock cell of urethral epithelium A hillock cell that is part of the urethra. Synonyms: hillock cell of urethra http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hillock cell of prostatic urethral epithelium A hillock cell that is part of the prostatic urethra. Synonyms: hillock cell of prostatic urethra http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tracheobronchial serous cell Any serous secreting cell that is part of the tracheobronchial epithelium. Synonyms: serous cell of tracheobronchial tree http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tracheobronchial chondrocyte Any chondrocyte that is part of the tracheobronchial tree. Synonyms: chondrocyte of tracheobronchial tree http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tracheobronchial goblet cell Any goblet cell that is part of the tracheobronchial epithelium. Synonyms: goblet cell of tracheobronchial tree http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lung parenchyma resident eosinophil An eosinophil with a ring-shaped nucleus that is resident in the lung parenchyma. In mouse, lung parenchyma resident eosinophils are IL-5-independent Siglec-F(intermediate) CD62L+ CD101(low). In human, they are Siglec-8+ CD62L+ IL-3R(low). Synonyms: lung-resident eosinophil, rEos http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lymphatic vessel smooth muscle cell A smooth muscle cell that is part of any lymphatic vessel. Synonyms: smooth muscle cell of lymphatic vessel http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
blood vessel smooth muscle cell A smooth muscle cell that is part of any blood vessel. Synonyms: smooth muscle cell of blood vessel http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tracheobronchial smooth muscle cell A smooth muscle cell that is part of the tracheobronchial tree. Synonyms: smooth muscle cell of tracheobronchial tree http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
extrahepatic cholangiocyte An epithelial cell of the extrahepatic bile ducts, including the left and right hepatic duct, common hepatic duct, and common bile duct. They are columnar in shape, and have a large nuclear-to-cytoplasmic ratio relative to small/intrahepatic cholangiocytes. Synonyms: large bile duct cholangiocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endothelial cell of periportal hepatic sinusoid An endothelial cell found in the periportal region hepatic sinusoid, near the portal triad. The fenestrae of these cells are larger but fewer in number compared with those of endothelial cells near the centrilobular region of the hepatic sinusoid. Synonyms: periportal LSEC, periportal hepatic sinusoidal endothelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endothelial cell of pericentral hepatic sinusoid An endothelial cell found in the centrilobular region hepatic sinusoid, near the central vein. The fenestrae of these cells are smaller but more numerous compared with those of endothelial cells near the periportal region of the hepatic sinusoid. Synonyms: central venous hepatic sinusoidal endothelial cell, pericentral LSEC http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
periportal region hepatocyte Any hepatocyte that is part of the liver lobule periportal region. These cells are primarily involved in oxidative energy metabolism. Synonyms: periportal hepatocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
midzonal region hepatocyte Any hepatocyte that is part of the liver lobule midzonal region. These cells have mixed functionality in comparison with those in the other two regions of the liver lobule. Synonyms: midzonal hepatocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
centrilobular region hepatocyte Any hepatocyte that is part of the liver lobule centrilobular region. These cells are the primary location for the biotransformation of drugs. Synonyms: centrilobular hepatocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
intestine goblet cell Goblet cells reside throughout the length of the small and large intestine and are responsible for the production and maintenance of the protective mucus blanket by synthesizing and secreting high-molecular-weight glycoproteins known as mucins. Human intestinal goblet cells secrete the MUC2 mucin, as well as a number of typical mucus components: CLCA1, FCGBP, AGR2, ZG16, and TFF3. Synonyms: intestinal goblet cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
intestinal tuft cell A tuft cell that is part of the intestinal epithelium, characterized by a distinctive apical tuft and lateral cytospinules connecting to neighbouring cells. This cell senses luminal stimuli via taste receptors and succinate signalling, initiating type 2 immune responses through the secretion of interleukin-25 while modulating epithelial regeneration through prostaglandin synthesis. It expresses key molecular markers such as doublecortin-like kinase 1 (DCLK1) in mice (Hendel et al., 2022), and KIT proto-oncogene in humans (Huang et al., 2024). Developed from intestinal crypt stem cells, this cell requires transcription factor POU2F3 for its development. Synonyms: intestinal brush cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
gut mesenchymal lymphoid tissue organizer cell A mesenchymal stromal cell found in the gut during development, and interacts with lymphoid tissue inducer (LTi) cells to drive secondary lymphoid organ formation (Prados et al., 2021). It expresses LTβR, PDGFRα, and VCAM, and upon activation secretes chemokines(e.g. CXCL13) and cytokines to organise lymphoid tissue architecture and recruit immune cells in both mice and humans (Denton el al., 2019; Elmentaite et al., 2021). As a multipotent progenitor, an mLTo cell differentiates into adult stromal subsets, including fibroblastic reticular cells (FRCs) (Prados et al., 2021), and its descendants persist in the adult gut-associated lymphoid tissues to maintain immune homeostasis(Denton el al., 2019; Lütge et al., 2021). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
V1delta gamma-delta T cell A mature gamma-delta T Cell with T cell receptors consisting of the Vδ1 segment paired with various V gamma chains. This cell is enriched in the gut, skin (Davey et al., 2018) and the female reproductive tract (Wu et al., 2022). It exhibits potent cytotoxic capabilities through perforin/granzyme and death receptor pathways. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mucosal-associated invariant T cell, human A mucosal-associated invariant T (MAIT) cell found in various tissues including human blood, liver, gut, and lung, characterised by a semi-invariant T cell receptor (TCR) comprising TRAV1-2 (Vα7.2) predominantly paired with TRAJ33, and high expression of CD161. Upon activation, MAIT cells produce inflammatory cytokines, including IFN-γ, TNF-α, and IL-17. Synonyms: mucosal-associated invariant T lymphocyte, human, mucosal-associated invariant T-cell, human, mucosal-associated invariant T-lymphocyte, human http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
spiral ligament fibrocyte An otic fibrocyte that is part of the spiral ligament. This cell is crucial in maintaining the endocochlear potential, regulating blood flow, participating in immune responses by secreting chemokines including MCP-1 and MIP-2, and producing extracellular matrix proteins such as collagen and cochlin. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
OB-Dopa-GABA A transcriptomically defined GABAergic neuron coexpressing dopamine located in the olfactory bulb and part of the striatum. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hair follicle associated fibroblast A specialized dermal fibroblast within the hair follicle mesenchymal compartment that participates in epithelial-mesenchymal signaling to regulate hair morphogenesis, cycling, and homeostasis through production of inductive signals and extracellular matrix maintenance. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hair follicle isthmus-associated fibroblast A fibroblast that is part of the hair follicle isthmus (mid-hair shaft). In humans, this cell expresses CRABP1/COCH/RSPO4 and tendon-associated genes (MKX, TNMD). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
dermal sheath fibroblast A fibroblast forming the connective tissue sheath that encloses the hair follicle epithelium from the level of the bulge downward to the hair bulb. This cell expresses characteristic markers, including DPEP1 in humans and COL11A1 and ACTA2 (alpha-smooth muscle actin) in mice and humans. Dermal sheath fibroblast possesses contractile properties mediated by calcium-calmodulin-myosin light chain kinase signalling, generating centripetal force during hair follicle catagen that relocates the dermal papilla to the stem cell niche. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
intrinsically photosensitive retinal ganglion cell A retinal ganglion cell that is intrinsically photosensitive, functioning as a non-image-forming photoreceptor, distinguished from rod and cone photoreceptors by the expression of the photopigment melanopsin in mice and humans (Hattar et al., 2002; Tri Hoang Do & Yau, 2015). Located primarily in the ganglion cell layer with some displaced somata in the inner nuclear layer, this neuron depolarises directly in response to environmental irradiance (Tri Hoang Do & Yau, 2015). It projects via the retinohypothalamic tract to central targets, including the suprachiasmatic nucleus (SCN) for circadian photoentrainment and the olivary pretectal nucleus (OPN) for the pupillary light reflex. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
transitional principal-intercalated cell of kidney collecting duct A transitional cell located in the renal collecting duct that co-expresses markers of both principal cell (PC) and intercalated cell (IC). This hybrid cell is enriched in Chronic Kidney Disease (CKD). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
osteochondral skeletal stem cell A tissue-specific stem cell with long-term self-renewal capacity that is restricted to generating bone, cartilage, and stromal cell lineages. This cell is primarily located in the growth plate (resting zone), periosteum, and subchondral bone regions, and is marked by high clonogenicity and robust multipotent differentiation potential in both osteogenic and chondrogenic lineages. Distinctively, ocSSC lacks adipogenic capacity, distinguishing it from other mesenchymal stem cell populations. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
M0 macrophage A macrophage that has not yet undergone polarization into a specific macrophage subtype. These cells are non-activated and have the potential to differentiate into inflammatory (M1) or alternatively activated (M2) macrophage subtypes in response to appropriate stimuli. Synonyms: naive macrophage, non-activated macrophage, resting-state macrophages http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
proliferative fibrochondrocyte A fibrochondrocyte located in fibrocartilage that exhibits active proliferation capacity and is in S phase of the cell cycle. It functions as a progenitor cell positioned at the root of developmental trajectories alongside fibrochondrocyte progenitors (FCP), with the capacity to diverge toward one of two developmental fates: (1) fibrochondrocytes and prehypertrophic chondrocytes, or (2) regulatory chondrocytes and prehypertrophic chondrocytes. It is characterised by co-expression of COL1A1, the growth factors FGF7 and CTGF, and the cell-cycle genes STMN1, KIAA0101, and MCM3 in humans. During early progenitor differentiation, FGF7 and COL1A1 expression increases and then declines as the cell commits to terminal fates. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
regulatory chondrocyte A chondrocyte located mainly in the superficial zone of articular cartilage. In healthy human cartilage, regulatory chondrocytes are characterized by expression of EIF5A, PGK1, ANXA1, and TUBA1A. During osteoarthritis, a distinct subpopulation expands, marked by high expression of CHI3L1, CHI3L2, CRTAC1, and AEBP1, with enrichment for signaling pathway regulation (including Toll-like receptor, mTOR, and TGF-beta signaling) and antigen-processing gene expression, with a small proportion expressing MHC class II genes, suggesting potential immune cell-like regulatory functions during osteoarthritis progression. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
homeostatic chondrocyte A chondrocyte identified in both healthy and osteoarthritic human articular cartilage, and in intervertebral disc tissue. In healthy articular cartilage, a homeostatic chondrocyte is characterised by the expression of TXNIP, IFITM3, GDF15, and TIMP1 (Wang et al., 2021), among other extracellular matrix and regulatory molecules. This cell maintains cartilage integrity by producing key ECM components and supporting baseline tissue homeostasis. In OA cartilage, this cell is enriched for genes related to cellular homeostasis modulation, including regulation of the cell cycle, development, and RNA metabolism (Ji et al., 2018). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibrochondrocyte progenitor cell A mesenchymal progenitor cell located in fibrocartilaginous tissues, along the fibrochondrocytic differentiation pathway that co-expresses both fibrochondrocyte markers (COL1A1, COL3A1) and mesenchymal stem cell markers (MCAM/CD146, MYLK) in humans. This cell serves as a progenitor for mature fibrochondrocytes and other meniscal cell types, with differentiation regulated by TGF-β signaling, focal adhesion, and extracellular matrix-receptor interaction pathways. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
prehypertrophic chondrocyte A post-proliferative chondrocyte in the prehypertrophic zone of the cartilage tissue, located between the proliferative and hypertrophic zones. This cell is characterised by increased cell volume and expression of Indian Hedgehog (Ihh), PTH1R, and Runx2/3 in both humans and mice (Hallett et al., 2021). It coordinates the PTHrP-Ihh feedback loop that regulates chondrocyte differentiation and functions as a signalling hub for communication between proliferative chondrocytes, hypertrophic chondrocytes, and periosteal osteoblasts (Hallett et al., 2021). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
effector chondrocyte A metabolically highly active chondrocyte that is identified in the cartilaginous tissues, including articular cartilage and intervertebral disc cartilage. In the human articular cartilage, this cell is marked by genes such as CYTL1, FRZB, CLEC3A, and S100B (Ji et al., 2018; Raut et al.,2025). This cell demonstrates strong metabolic activity and is implicated in extracellular matrix regulation and adaptive responses (Ji et al., 2018; Gan et al., 2021; Raut et al.,2025). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cuboidal epithelial cell An epithelial cell that has a cuboidal morphology. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD4-positive exhausted alpha-beta T cell A CD4-positive alpha-beta T cell that displays impaired function and altered differentiation as a result of chronic antigenic stimulation (e.g., chronic infection, tumors, or persistent inflammation). This state is characterised by sustained expression of PD-1 as a shared feature. Additional exhaustion-associated molecules, including the transcription factor TOX, and context- or stage-dependent changes in markers such as LAG-3, TIM-3, CD39, and T-bet, may also be observed; however, the expression levels of these molecules vary depending on exhaustion stage and tissue environment. Synonyms: CD4+ exhausted T lymphocyte, exhausted CD4 T cell, exhausted CD4-positive T cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD8-positive exhausted alpha-beta T cell A CD8-positive alpha-beta T cell that displays impaired function and altered differentiation as a result of chronic antigenic stimulation (e.g., chronic infection, tumours, or persistent inflammation). This state is characterised by sustained expression of PD-1 as a shared feature. Additional exhaustion-associated molecules, including expression of the transcription factor TOX and reduced T-bet, and context- or stage-dependent changes in markers such as LAG-3, TIM-3, CD39, and EOMES, may also be observed; however, the expression levels of these molecules vary depending on exhaustion stage and disease context. Synonyms: CD8+ exhausted T lymphocyte, exhausted CD8 T cell, exhausted CD8-positive T cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
oRGC2 A conserved retinal ganglion cell orthotype whose transcriptomic profile groups together ON parasol RGCs from primate foveal and peripheral retina with their molecularly homologous mouse α RGC subtype (ON-transient α RGC, C41) (Hahn et al., 2023; Tran et al., 2019). Reference to the transcriptomic evidence is found at: GSE237215. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stem cell memory CD4-positive, alpha-beta T cell A CD4-positive memory alpha-beta T cell with stem-like properties that is long-lived, retains a naïve-like phenotype, and exhibits self-renewal and multipotent differentiation capacity. This cell acts as a stem-like reservoir capable of regenerating central and effector memory T cell subsets. Synonyms: CD4+ T memory stem cell, CD4+ TSCM cell, CD4-positive TSCM cell, stem cell memory CD4+ T-cell, stem cell memory CD4+ T-lymphocyte, stem cell memory CD4+ alpha-beta T cell, stem cell memory CD4-positive, alpha-beta T lymphocyte, stem cell–like memory CD4+ T cell, stem cell–like memory CD4-positive, alpha-beta T cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stem cell memory CD8-positive, alpha-beta T cell A CD8-positive memory alpha-beta T cell with stem-like properties that is long-lived, retains a naïve-like phenotype, and exhibits self-renewal and multipotent differentiation capacity. This cell acts as a stem-like reservoir capable of regenerating central and effector memory T cell subsets. Synonyms: CD8+ T memory stem cell, CD8+ TSCM cell, CD8-positive TSCM cell, stem cell memory CD8+ T-cell, stem cell memory CD8+ T-lymphocyte, stem cell memory CD8+ alpha-beta T cell, stem cell memory CD8-positive, alpha-beta T lymphocyte, stem cell–like memory CD8+ T cell, stem cell–like memory CD8-positive, alpha-beta T cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
intestinal intraepithelial lymphocyte A T cell that is located in the intestinal epithelium and is capable of a mucosal immune response. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
oRGC1 A conserved retinal ganglion cell orthotype whose transcriptomic profile groups together OFF midget RGCs from primate foveal and peripheral retina with their molecularly homologous mouse alpha RGC subtype (OFF-sustained alpha-RGC, C42) (Hahn et al., 2023; Tran et al., 2019). Reference to the transcriptomic evidence is found at: GSE237215. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
superficial zone articular chondrocyte An articular chondrocyte located in the most superficial zone of articular cartilage, characterized by flattened morphology and tangential alignment parallel to the joint surface, and residing within a matrix of fine collagen fibrils and relatively low proteoglycan content. In mice and humans, this cell typically expresses lubricin (PRG4) and contributes to lubrication and resistance to shear and tensile forces at the cartilage surface. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
middle zone articular chondrocyte An articular chondrocyte located in the middle (transitional) zone of articular cartilage, characterized by round morphology and relatively random spatial organization, and residing in a matrix enriched in proteoglycans and thicker collagen fibrils oriented obliquely to the articular surface. This cell contributes to the largest volume fraction of articular cartilage and functions primarily in distributing and absorbing compressive loads between the superficial and deep zones. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
deep zone articular chondrocyte An articular chondrocyte located in the deep (radial) zone of articular cartilage, characterized by columnar arrangement perpendicular to the joint surface and residence within a matrix containing the highest proteoglycan concentration and large-diameter collagen fibrils oriented radially. In humans, this cell expresses collagen type X (COL10A1) and provides maximal resistance to compressive forces. It is positioned adjacent to the tidemark, where collagen fibrils extend into the calcified cartilage to anchor the articular cartilage to subchondral bone. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
calcified zone articular chondrocyte An articular chondrocyte located in the calcified cartilage zone below the tidemark at the interface between articular cartilage and subchondral bone, embedded within a mineralized extracellular matrix. In humans, this cell exhibits a hypertrophic-like phenotype and typically expresses collagen type X (COL10A1). Together with the surrounding calcified matrix, it forms a transitional region that mechanically couples the deep articular cartilage to the underlying subchondral bone. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
oRGC4 A conserved retinal ganglion cell orthotype whose transcriptomic profile groups together ON midget RGCs from primate foveal and peripheral retina with their molecularly homologous mouse alpha RGC subtype (ON-sustained α RGC, C43) (Hahn et al., 2023; Tran et al., 2019). Reference to the transcriptomic evidence is found at: GSE237215. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
oRGC5 A conserved retinal ganglion cell orthotype whose transcriptomic profile groups together OFF parasol RGCs from primate foveal and peripheral retina with their molecularly homologous mouse α RGC subtype (OFF-transient α RGC, C45) (Hahn et al., 2023; Tran et al., 2019). Reference to transcriptomic evidence can be found at: GSE237215. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fasciacyte A mesenchymal stromal cell of the deep fascia (e.g., fascia lata) that is vimentin-positive, CD68-negative, and S-100A4-positive, organized in small clusters at the interface between fibrous fascial sublayers and loose connective tissue. It is specialized for hyaluronan-rich ECM biosynthesis, as evidenced by HAS2 mRNA expression, Alcian Blue staining, and anti-HABP immunoreactivity, and functions to regulate fascial gliding and viscoelasticity. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
migratory muscle precursor Muscle precursor cells that delaminate from the dermomyotome after epithelial-to-mesenchymal transition (EMT) and undergo long-range migration while retaining proliferative capacity. Synonyms: MMP http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
serous demilune cell of salivary gland A serous secreting cell that is part of a salivary gland, forming crescent-shaped (demilune) caps at the distal ends of mucous acini in mixed glands. Prominent in human submandibular and sublingual glands, this cell delivers its watery, enzyme-rich secretions including alpha-amylase through intercellular canaliculi that run between adjacent mucous cells to reach the acinar lumen (Amano et al., 2012). In rodents, these cells also express neuronal nitric oxide synthase (nNOS). Synonyms: serous demilune cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
basal duct cell of salivary gland A basal cell that is part of the duct of a salivary gland, characterized by an undifferentiated phenotype, expression of KRT5, and a position surrounding the striated ductal epithelium. This cell is presumed to function as a salivary gland stem/progenitor cell capable of regenerating ductal and potentially acinar cell populations (Yura and Hamada, 2023). In mice, Lgr5-expressing cells within this compartment demonstrate tripotent capacity, able to generate acinar, ductal, and myoepithelial cell lineages. Synonyms: basal ductal cell of salivary gland http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
periductal fibroblast of salivary gland A fibroblast that is part of the stroma of a salivary gland, positioned in the periductal connective tissue surrounding the ductal system. This cell maintains the extracellular matrix framework around salivary gland ducts and participates in immunomodulatory signaling. In the context of Sjögren's syndrome, periductal fibroblasts respond to IL-13 stimulation by upregulating VCAM-1, PDPN, and ICAM-1, contributing to the formation of tertiary lymphoid structures (Nayar et al., 2019). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
junctional epithelial cell An epithelial cell that is part of the junctional epithelium of the gingiva, forming a collar-like band around the cervix of the tooth. This cell attaches to the tooth surface via hemidesmosomes and an internal basal lamina rich in laminin-332 and ODAM (Gavriiloglou et al., 2024). The junctional epithelium is a stratified squamous non-keratinized epithelium ranging from 15-30 cell layers coronally to 1-3 cell layers apically. This cell expresses cytokeratin 19 (CK19) as a specific marker, along with ODAM and FDC-SP, and participates in innate immune defense by producing IL-8, IL-1alpha, and MMP-7, facilitating the transmigration of polymorphonuclear leukocytes through the epithelium (Gavriiloglou et al., 2024). This cell has a high turnover rate, with complete renewal occurring every 4-6 days (Lin et al., 2025), and develops from the reduced enamel epithelium during tooth eruption, although it can regenerate de novo without this precursor. Synonyms: JE cell, cell of junctional epithelium http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tuft cell of parotid gland A tuft cell that is part of the epithelium of the parotid gland, localized to the striated ducts and never observed in acini. This cell is characterized by expression of POU2F3 and is expected to possess chemosensory function consistent with tuft cells in other tissues. Immunohistochemical analysis of normal human parotid gland tissue detected POU2F3-positive cells as a very rare population within the ductal compartment, positioned on the luminal side (Hoki et al., 2024). Synonyms: parotid gland tuft cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tuft cell of sublingual gland A tuft cell that is part of the epithelium of the sublingual gland, localized to the ductal compartment. This cell is characterized by expression of POU2F3, consistent with tuft cell identity. Immunohistochemical analysis detected POU2F3-positive cells in normal human sublingual gland tissue (Hoki et al., 2024). Synonyms: sublingual gland tuft cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ionocyte of salivary gland An ionocyte that is part of a salivary gland, localized to the ductal compartment on the luminal side. This specialized epithelial cell is characterized by expression of FOXI1 and is involved in regulating and maintaining osmotic pressure within the glandular environment (Dong et al., 2024). In normal human salivary glands, FOXI1-positive cells constitute less than 5% of ductal epithelial cells and are found exclusively in ducts, never in acini, across all major gland types including parotid, submandibular, sublingual, and minor salivary glands (Hoki et al., 2024). Like ionocytes in other tissues, this cell is expected to express high levels of CFTR and possess abundant mitochondria and ion transporters. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myoepithelial cell of salivary gland A myoepithelial cell that is part of a salivary gland, positioned between the basal lamina and the secretory or ductal epithelial cells surrounding acini and intercalated ducts. This cell adopts a stellate morphology with four to eight cellular processes around acini and an elongated form parallel to the ductal axis around intercalated ducts (Amano et al., 2012). It expresses alpha-smooth muscle actin (ACTA2/alpha-SMA) as a primary marker, along with p63 and aquaporin 1 (AQP1), and contracts rhythmically in response to neural stimulation to facilitate saliva expulsion from secretory acini into the ductal system (Amano et al., 2012). This cell also produces FGF7, which activates FGFR2b-dependent transcriptional programs essential for seromucous acinar cell differentiation (Aure et al., 2023). In mice, myoepithelial cells express SOX2 and possess regenerative capacity, contributing to acinar cell restoration during tissue repair after severe injury. Synonyms: salivary gland myoepithelial cell, salivary myoepithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesonephric nephron tubule epithelial cell Any epithelial cell that is part of some mesonephric nephron tubule. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
spinal cord radial glial cell Any radial glial cell that is part of some spinal cord. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stretch receptor cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stratified keratinized epithelial stem cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stratified non keratinized epithelial stem cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pronephric nephron tubule epithelial cell Any epithelial cell that is part of some pronephric nephron tubule. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
metanephric nephron tubule epithelial cell Any epithelial cell that is part of some metanephric nephron tubule. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lung goblet cell Any goblet cell that is part of some lung epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cardiac valve cell A cell that is part of a cardiac valve. Synonyms: heart valve cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pillar cell A rod-like cell in the inner ear, having their heads joined and their bases on the basilar membrane widely separated so as to form a spiral tunnel known as the tunnel of Corti. Synonyms: pillar cell of cochlea, pillar cell of corti, rod cell of Corti http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
growth plate cartilage chondrocyte Any chondrocyte that is part of some growth plate cartilage. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lung multiciliated epithelial cell An epithelial cell that is part of the lung epithelium. This cell is characterised by the presence of cilia on its apical surface. Synonyms: lung ciliated cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lung secretory cell Any secretory cell that is part of some lung. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
trophectodermal cell An extraembryonic cell that is part of the trophectoderm, representing the first lineage to differentiate in the embryo. This cell is crucial for implantation into the uterine wall and differentiates into trophoblast cells, which contribute to placenta formation and facilitate maternal-fetal nutrient and signal exchange. Synonyms: trophectoderm cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle cell of small intestine A smooth muscle cell that is part of the small intestine. Synonyms: non-striated muscle fiber of small intestine http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle fiber of duodenum A smooth muscle cell that is part of the duodenum. Synonyms: non-striated muscle fiber of duodenum http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle fiber of jejunum A smooth muscle cell that is part of the jejunum. Synonyms: non-striated muscle fiber of jejunum http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle fiber of ileum A smooth muscle cell that is part of the ileum. Synonyms: non-striated muscle fiber of ileum http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle cell of large intestine A smooth muscle cell that is part of the large intestine. Synonyms: non-striated muscle fiber of large intestine http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle cell of colon A smooth muscle cell that is part of the colon. Synonyms: non-striated muscle fiber of colon http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle cell of cecum A smooth muscle cell that is part of the cecum. Synonyms: non-striated muscle fiber of cecum, smooth muscle fiber of cecum http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle fiber of ascending colon A smooth muscle cell that is part of the ascending colon. Synonyms: non-striated muscle fiber of ascending colon http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle fiber of transverse colon A smooth muscle cell that is part of the transverse colon. Synonyms: non-striated muscle fiber of transverse colon http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle fiber of descending colon A smooth muscle cell that is part of the descending colon. Synonyms: non-striated muscle fiber of descending colon http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle cell of sigmoid colon A smooth muscle cell that is part of the sigmoid colon. Synonyms: non-striated muscle fiber of sigmoid colon http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle cell of rectum A smooth muscle cell that is part of the rectum. Synonyms: non-striated muscle fiber of rectum, smooth muscle fiber of rectum http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myocyte of anterior internodal tract A muscle cell that is part of the anterior internodal tract. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myocyte of atrial branch of anterior internodal tract A muscle cell that is part of the atrial branch of anterior internodal tract. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myocyte of atrial septal branch of anterior internodal tract A muscle cell that is part of the atrial septal branch of anterior internodal tract. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myocyte of middle internodal tract A muscle cell that is part of the middle internodal tract. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myocyte of posterior internodal tract A muscle cell that is part of the posterior internodal tract. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of urethra An epithelial cell that is part of the urethra. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesothelial cell of dura mater A mesothelial cell that is part of the dura mater. Synonyms: squamous mesothelial cell of dura mater http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of connective tissue of prostate A fibroblast that is part of the connective tissue of prostate. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of outer membrane of prostatic capsule A fibroblast that is part of the outer membrane of prostatic capsule. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of subepithelial connective tissue of prostatic gland A fibroblast that is part of the subepithelial connective tissue of prostatic gland. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of papillary layer of dermis A fibroblast that is part of the papillary layer of dermis. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of areolar connective tissue A fibroblast that is part of the areolar connective tissue. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of connective tissue of nonglandular part of prostate A fibroblast that is part of the connective tissue of nonglandular part of prostate. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of connective tissue of glandular part of prostate A fibroblast that is part of the connective tissue of glandular part of prostate. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of tunica adventitia of artery A fibroblast that is part of the tunica adventitia of artery. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of dense regular elastic tissue A fibroblast that is part of the dense regular elastic tissue. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibrocyte of adventitia of ureter A stromal cell that is part of the outer adventitial layer of the ureter. This cell type is marked by expression of periostin (POSTN) in mice, and it is derived from Foxd1+ mesenchymal progenitors around embryonic day 12.5. The adventitial fibrocyte initiates differentiation earlier than smooth muscle cells and becomes terminally differentiated by E16.5-18.5 in mice, exhibiting low proliferative capacity in adulthood. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epicardial adipocyte An adipocyte that is part of the epicardial fat. Synonyms: adipocyte of epicardial fat, epicardial fat cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
adipocyte of epicardial fat of right ventricle An adipocyte that is part of the epicardial fat of right ventricle. Synonyms: epicardial adipocyte of right ventricle, epicardial fat cell of right ventricle http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
adipocyte of epicardial fat of left ventricle An adipocyte that is part of the epicardial fat of left ventricle. Synonyms: epicardial adipocyte of left ventricle, epicardial fat cell of left ventricle http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
bronchial goblet cell A goblet cell that is part of the epithelium of bronchus. Synonyms: goblet cell of epithelium of bronchus http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
gastric goblet cell A goblet cell that is part of the epithelium of stomach. Synonyms: goblet cell of epithelium of stomach http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
gastric cardiac gland goblet cell A goblet cell that is part of the epithelium of gastric cardiac gland. Synonyms: goblet cell of epithelium of gastric cardiac gland http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
principal gastric gland goblet cell A goblet cell that is part of the epithelium of principal gastric gland. Synonyms: goblet cell of epithelium of principal gastric gland http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
intestinal villus goblet cell A goblet cell that is part of the epithelium of intestinal villus. Synonyms: goblet cell of epithelium of intestinal villus http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
large intestine goblet cell A goblet cell that is part of the epithelium of large intestine. Synonyms: goblet cell of epithelium of large intestine http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
large intestine crypt goblet cell A goblet cell that is part of the epithelium of crypt of Lieberkuhn of large intestine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pancreatic goblet cell A goblet cell that is part of the epithelium of pancreatic duct. Synonyms: goblet cell of epithelium of pancreatic duct http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pyloric gastric gland goblet cell A goblet cell that is part of the epithelium of pyloric gland. Synonyms: goblet cell of epithelium of pyloric gland http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
duodenal goblet cell A goblet cell that is part of the epithelium proper of duodenum. Synonyms: goblet cell of epithelium proper of duodenum http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
jejunal goblet cell A goblet cell that is part of the epithelium proper of jejunum. Synonyms: goblet cell of epithelium proper of jejunum http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ileal goblet cell A goblet cell that is part of the epithelium proper of ileum. Synonyms: goblet cell of epithelium proper of ileum http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
appendix goblet cell A goblet cell that is part of the epithelium proper of appendix. Synonyms: goblet cell of epithelium proper of appendix http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tracheal goblet cell A goblet cell that is part of the epithelium of trachea. Synonyms: goblet cell of epithelium of trachea http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
serous cell of epithelium of trachea A serous secreting cell that is part of the epithelium of trachea. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
serous cell of epithelium of bronchus A serous secreting cell that is part of the epithelium of bronchus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
serous cell of epithelium of terminal bronchiole A serous secreting cell that is part of the epithelium of terminal bronchiole. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
serous cell of epithelium of lobular bronchiole A serous secreting cell that is part of the epithelium of bronchiole. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
enterocyte of epithelium of small intestine An enterocyte that is part of the epithelium of small intestine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
enterocyte of epithelium of intestinal villus An enterocyte that is part of the epithelium of intestinal villus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
enterocyte of epithelium of duodenal gland An enterocyte that is part of the epithelium of duodenal gland. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
enterocyte of epithelium of crypt of Lieberkuhn of small intestine An enterocyte that is part of the epithelium of crypt of Lieberkuhn of small intestine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
enterocyte of epithelium proper of small intestine An enterocyte that is part of the epithelium proper of small intestine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
enterocyte of epithelium proper of duodenum An enterocyte that is part of the epithelium proper of duodenum. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
enterocyte of epithelium proper of jejunum An enterocyte that is part of the epithelium proper of jejunum. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
enterocyte of epithelium proper of ileum An enterocyte that is part of the epithelium proper of ileum. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
paneth cell of epithelium of small intestine A paneth cell that is part of the epithelium of small intestine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
paneth cell of epithelium proper of small intestine A Paneth cell that is part of the epithelium proper of small intestine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
paneth cell of epithelium of crypt of Lieberkuhn of small intestine A paneth cell that is part of the epithelium of crypt of Lieberkuhn of small intestine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
enterocyte of epithelium proper of large intestine An enterocyte that is part of the epithelium proper of large intestine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
colonocyte An enterocyte (absorptive epithelial cell) of the colonic epithelium, characterized by a columnar shape. This cell is responsible for the absorption, transport, and metabolization of short-chain fatty acids (SCFAs) produced by gut bacteria, as well as the transport and absorption of water and electrolytes. Synonyms: enterocyte of colon http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
basal cell of epithelium of trachea A basal cell that is part of the epithelium of trachea. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
basal cell of epithelium of bronchus A basal cell found in the bronchus epithelium. Synonyms: basal cell of bronchus http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
basal cell of epithelium of terminal bronchiole A basal cell that is part of the epithelium of terminal bronchiole. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
basal cell of epithelium of respiratory bronchiole A basal cell that is part of the epithelium of respiratory bronchiole. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
basal cell of epithelium of lobular bronchiole A basal cell that is part of the epithelium of bronchiole. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
microfold cell of epithelium of small intestine A M cell that is part of the epithelium of small intestine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
microfold cell of epithelium of intestinal villus A M cell that is part of the epithelium of intestinal villus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
microfold cell of epithelium proper of small intestine A M cell that is part of the epithelium proper of small intestine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
microfold cell of epithelium proper of duodenum A M cell that is part of the epithelium proper of duodenum. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
microfold cell of epithelium proper of jejunum A M cell that is part of the epithelium proper of jejunum. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
microfold cell of epithelium proper of ileum A M cell that is part of the epithelium proper of ileum. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
microfold cell of epithelium proper of appendix A M cell that is part of the epithelium proper of appendix. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
microfold cell of epithelium proper of large intestine A M cell that is part of the epithelium proper of large intestine. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
transitional myocyte of interatrial septum A transitional myocyte that is part of the interatrial septum. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
transitional myocyte of interventricular septum A transitional myocyte that is part of the interventricular septum. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
transitional myocyte of atrial branch of anterior internodal tract A transitional myocyte that is part of the atrial branch of anterior internodal tract. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
transitional myocyte of anterior internodal tract A transitional myocyte that is part of the anterior internodal tract. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
transitional myocyte of atrial septal branch of anterior internodal tract A transitional myocyte that is part of the atrial septal branch of anterior internodal tract. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
transitional myocyte of middle internodal tract A transitional myocyte that is part of the middle internodal tract. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
transitional myocyte of posterior internodal tract A transitional myocyte that is part of the posterior internodal tract. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
transitional myocyte of anterior division of left branch of atrioventricular bundle A transitional myocyte that is part of the anterior division of left branch of atrioventricular bundle. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
transitional myocyte of septal division of left branch of atrioventricular bundle A transitional myocyte that is part of the septal division of left branch of atrioventricular bundle. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
transitional myocyte of left branch of atrioventricular bundle A transitional myocyte that is part of the left branch of atrioventricular bundle. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
transitional myocyte of right branch of atrioventricular bundle A transitional myocyte that is part of the right branch of atrioventricular bundle. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
transitional myocyte of atrial part of atrioventricular bundle A transitional myocyte that is part of the atrial part of atrioventricular bundle. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
transitional myocyte of ventricular part of atrioventricular bundle A transitional myocyte that is part of the ventricular part of atrioventricular bundle. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
transitional myocyte of posterior division of left branch of atrioventricular bundle A transitional myocyte that is part of the posterior division of left branch of atrioventricular bundle. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myocardial endocrine cell of septal division of left branch of atrioventricular bundle A myocardial endocrine cell that is part of the septal division of left branch of atrioventricular bundle. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Purkinje myocyte of interventricular septum A Purkinje myocyte that is part of the interventricular septum. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
dense-core granulated cell of epithelium of trachea A Feyrter cell that is part of the epithelium of trachea. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type 1 vestibular sensory cell of stato-acoustic epithelium A type I vestibular sensory cell that is part of the stato-acoustic epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type 1 vestibular sensory cell of epithelium of macula of utricle of membranous labyrinth A type I vestibular sensory cell that is part of the epithelium of macula of utricle of membranous labyrinth. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type 1 vestibular sensory cell of epithelium of macula of saccule of membranous labyrinth A type I vestibular sensory cell that is part of the epithelium of macula of saccule of membranous labyrinth. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type 1 vestibular sensory cell of epithelium of crista of ampulla of semicircular duct of membranous labyrinth A type I vestibular sensory cell that is part of the epithelium of crista of ampulla of semicircular duct of membranous labyrinth. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type 2 vestibular sensory cell of stato-acoustic epithelium A type II vestibular sensory cell that is part of the stato-acoustic epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type 2 vestibular sensory cell of epithelium of macula of utricle of membranous labyrinth A type II vestibular sensory cell that is part of the epithelium of macula of utricle of membranous labyrinth. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type 2 vestibular sensory cell of epithelium of macula of saccule of membranous labyrinth A type II vestibular sensory cell that is part of the epithelium of macula of saccule of membranous labyrinth. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type 2 vestibular sensory cell of epithelium of crista of ampulla of semicircular duct of membranous labyrinth A type II vestibular sensory cell that is part of the epithelium of crista of ampulla of semicircular duct of membranous labyrinth. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
melanocyte of eyelid A melanocyte that is part of the eyelid. Synonyms: eyelid melanocyte, sebaceous gland of wolff http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myoepithelial cell of intralobular lactiferous duct A myoepithelial cell that is part of the intralobular part of terminal lactiferous duct. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endothelial cell of venous sinus of red pulp of spleen An endothelial cell that is part of the venous sinus of red pulp of spleen. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endothelial cell of hepatic sinusoid An endothelial cell that is part of the hepatic sinusoid. These cells possess flattened areas containing perforations about 0.1 micrometers in diameter, known as fenestrae. The fenestrae are arranged in groups known as sieve plates. Synonyms: LSEC, endotheliocyte of hepatic sinusoid, liver sinusoidal endothelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of appendix An epithelial cell that is part of the appendix. Synonyms: columnar epitheliocyte of appendix, epithelial cell of vermiform appendix http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myocyte of sinoatrial node A muscle cell that is part of the sinoatrial node. Synonyms: SA nodal myocyte, SA node cardiac muscle cell, sinoatrial node cell, sinoatrial node myocyte, sinuatrial node myocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myocyte of atrioventricular node A muscle cell that is part of the atrioventricular node. Synonyms: AV nodal myocyte, AV node cardiac muscle cell, AV node cell, atrioventricular node cell, atrioventricular node myocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endothelial cell of Peyer's patch An endothelial cell that is part of the small intestine Peyer's patch. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endothelial cell of arteriole An endothelial cell that is part of the arteriole. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endothelial cell of artery A blood vessel endothelial cell that is part of an arterial endothelium. Synonyms: arterial endothelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endothelial cell of venule An endothelial cell that is part of the venule. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of gallbladder An epithelial cell that is part of the gallbladder. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myoepithelial cell of sweat gland A myoepithelial cell that is part of the sweat gland. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myoepithelial cell of lactiferous alveolus A myoepithelial cell that is part of the mammary gland alveolus. Synonyms: basal cell of alveolus of lactiferous gland, myoepithelial cell of mammary alveolus http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myoepithelial cell of lactiferous duct A myoepithelial cell that is part of the lactiferous duct. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myoepithelial cell of terminal lactiferous duct A myoepithelial cell that is part of the terminal lactiferous duct. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
chromaffin cell of paraaortic body A chromaffin cell that is part of the paraaortic body. Synonyms: chromaffin cell of para-aortic body http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
chromaffin cell of paraganglion A chromaffin cell that is part of the paraganglion. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
chromaffin cell of adrenal gland A chromaffin cell that is part of the adrenal gland. Synonyms: adrenal chromaffin cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
adrenal cortex chromaffin cell A chromaffin cell that is part of the adrenal cortex. Synonyms: chromaffin cell of adrenal cortex http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stem cell of epidermis A somatic stem cell that is part of the epidermis. Synonyms: epidermal stem cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
conjunctival epithelial cell An epithelial cell that is part of the conjunctiva. Synonyms: epithelial cell of conjunctiva http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of lacrimal canaliculus An epithelial cell that is part of the lacrimal canaliculus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of external acoustic meatus An epithelial cell that is part of the external acoustic meatus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of lacrimal drainage system An epithelial cell that is part of the lacrimal drainage system. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of lacrimal sac An epithelial cell that is part of the lacrimal sac. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of nasolacrimal duct An epithelial cell that is part of the nasolacrimal duct. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of wall of inferior part of anal canal An epithelial cell that is part of the wall of inferior part of anal canal. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of viscerocranial mucosa An epithelial cell that is part of the viscerocranial mucosa. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
urothelial cell of trigone of urinary bladder An urothelial cell that is part of the trigone of urinary bladder. Synonyms: epithelial cell of vesical trigone http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ciliary muscle cell A smooth muscle cell that is part of the ciliary body. Synonyms: smooth muscle cell of ciliary body http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesothelial cell of anterior chamber of eye A mesothelial cell that is part of the anterior chamber of eyeball. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myoepithelial cell of dilator pupillae A myoepithelial cell that is part of the dilatator pupillae. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of stratum germinativum of esophagus A basal cell that is part of the epithelium of esophagus. Synonyms: basal cell of esophageal epithelium http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of sweat gland An epithelial cell that is part of the sweat gland. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of nephron An epithelial cell that is part of the nephron. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of glomerular capsule An epithelial cell that is part of the glomerular capsule. Synonyms: Bowmans capsule epithelial cell, epithelial cell of Bowman's capsule http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
parietal epithelial cell An epithelial cell that is part of the glomerular parietal epithelium. Synonyms: epithelial cell of parietal layer of glomerular capsule http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of intermediate tubule An epithelial cell that is part of the intermediate tubule. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney collecting duct epithelial cell An epithelial cell that is part of the collecting duct of renal tubule. Synonyms: epithelial cell of renal collecting tubule http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesothelial cell of parietal peritoneum A mesothelial cell that is part of the parietal peritoneum. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesothelial cell of visceral peritoneum A mesothelial cell that is part of the visceral peritoneum. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
melanocyte of skin A melanocyte that is part of the skin of body. Synonyms: skin melanocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
chromaffin cell of ovary A chromaffin cell that is part of the ovary. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
chromaffin cell of right ovary A chromaffin cell that is part of the right ovary. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
chromaffin cell of left ovary A chromaffin cell that is part of the left ovary. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myoepithelial cell of acinus of lactiferous gland A myoepithelial cell that is part of the acinus of lactiferous gland. Synonyms: basal cell of acinus of lactiferous gland http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myoepithelial cell of main lactiferous duct A myoepithelial cell that is part of the main lactiferous duct. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myoepithelial cell of primary lactiferous duct A myoepithelial cell that is part of the primary lactiferous duct. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myoepithelial cell of secondary lactiferous duct A myoepithelial cell that is part of the secondary lactiferous duct. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myoepithelial cell of tertiary lactiferous duct A myoepithelial cell that is part of the tertiary lactiferous duct. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myoepithelial cell of quarternary lactiferous duct A myoepithelial cell that is part of the quarternary lactiferous duct. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cardiac pacemaker cell of sinoatrial node A nodal myocyte that is part of the sinoatrial node. Synonyms: cardiac pacemaker cell of sinuatrial node, pacemaker cell of sinoatrial node, pacemaker cell of sinuatrial node http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
transitional myocyte of sinoatrial node A transitional myocyte that is part of the sinoatrial node. Synonyms: transitinal myocyte of sinuatrial node http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Purkinje myocyte of atrioventricular node A Purkinje myocyte that is part of the atrioventricular node. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
transitional myocyte of internodal tract A transitional myocyte that is part of the internodal tract. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
transitional myocyte of atrioventricular bundle A transitional myocyte that is part of the atrioventricular bundle. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myocardial endocrine cell of interventricular septum A myocardial endocrine cell that is part of the interventricular septum. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Purkinje myocyte of internodal tract A Purkinje myocyte that is part of the internodal tract. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Purkinje myocyte of atrioventricular bundle A Purkinje myocyte that is part of the atrioventricular bundle. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
basal cell of urothelium A basal cell that is part of the urothelium. Compared to other urothelial cell types, a basal cell of the urothelium is positioned along the basement membrane, is the most undifferentiated and serves a progenitor role. Synonyms: urothelial basal cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle cell of prostate A smooth muscle cell that is part of the prostate gland. Synonyms: smooth muscle fiber of prostate http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cholangiocyte An epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water. They are cuboidal epithelium in the small interlobular bile ducts, but become columnar and mucus secreting in larger bile ducts approaching the porta hepatis and the extrahepatic ducts. Synonyms: epithelial cell of bile duct http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
reticular cell of splenic cord A reticular cell that is part of the splenic cord. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesothelial cell of peritoneum A mesothelial cell that is part of the peritoneum. Synonyms: peritoneal mesothelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesothelial cell of pleura A mesothelial cell that is part of the pleura. Synonyms: pleural mesothelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesothelial cell of parietal pleura A mesothelial cell that is part of the parietal pleura. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesothelial cell of visceral pleura A mesothelial cell that is part of the visceral pleura. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
nephron tubule epithelial cell An epithelial cell that is part of a nephron tubule. Synonyms: kidney tubule epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
small intestine goblet cell A goblet cell that is part of the small intestine. Synonyms: goblet cell of epithelium of small intestine, goblet cell of small intestine, small intestinal goblet cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney cell A cell that is part of a kidney. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney interstitial cell A cell that is part of kidney interstitium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney medulla cell A cell that is part of a renal medulla. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney pelvis cell A cell that is part of a renal pelvis. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney tubule cell A cell that is part of a nephron tubule. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney glomerular epithelial cell Any kidney epithelial cell that is part of some glomerular epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney medulla collecting duct epithelial cell An epithelial cell that is part of a renal medulla collecting duct. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney inner medulla collecting duct epithelial cell An epithelial cell that is part of some inner medullary collecting duct. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney outer medulla collecting duct epithelial cell An epithelial cell that is part of an outer medullary collecting duct. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney cortex collecting duct epithelial cell An epithelial cell that is part of a cortical collecting duct. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney papillary duct principal epithelial cell Any kidney cell that is part of some papillary duct. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
inner renal cortex cell Any kidney cell that is part of some juxtamedullary cortex. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
papillary tips cell A cell that is part of a tip of a renal papilla. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lower urinary tract cell Any cell that is part of some lower urinary tract. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ureteral cell Any cell that is part of some ureter. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney nerve cell Any neuron that has its soma located in some kidney. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney corpuscule cell Any renal cortical epithelial cell that is part of some renal corpuscle. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney cortex tubule cell Any kidney tubule cell that is part of some renal cortex tubule. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney outer medulla cell Any kidney medulla cell that is part of some outer medulla of kidney. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney inner medulla cell Any kidney medulla cell that is part of some inner medulla of kidney. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
juxtaglomerular complex cell Any kidney cortical cell that is part of some juxtaglomerular apparatus. Synonyms: juxtaglomerulus cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney cortex interstitial cell A cell that is part of an interstitial compartment of a renal cortex. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney medulla interstitial cell A cell that is part of an interstitum of a renal medulla. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney interstitial myofibroblast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney interstitial fibroblast A fibroblast that is part of an interstitial compartment of a kidney. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney interstitial fibrocyte A stromal cell that infiltrates and resides in the kidney interstitium following injury, characterized by the co-expression of CD45 with mesenchymal markers including α-SMA, and collagen I in humans (Kim et al., 2023). This cell originates from circulating monocyte-derived fibrocytes. It produces extracellular matrix components, contributing to renal fibrosis by potentially differentiating into myofibroblasts upon infiltration into injured kidneys (Sun et al., 2016). Migration into the kidney is dependent on chemokine receptor signaling, particularly CCR2 in mice (Reich et al., 2013). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney interstitial alternatively activated macrophage http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney interstitial inflammatory macrophage http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney interstitial suppressor macrophage http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney resident macrophage A tissue-resident macrophage that is part of some kidney. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney resident dendritic cell A resident-dendritic cell that is part of a kidney. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney pelvis smooth muscle cell Any smooth muscle cell that is part of some kidney pelvis smooth muscle. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney pelvis urothelial cell Any kidney epithelial cell that is part of some kidney pelvis urothelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ureter urothelial cell A urothelial cell that is part of the urothelium of ureter. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ureter adventitial cell Any ureteral cell that is part of some adventitia of ureter. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney cortex collecting duct principal cell Any renal principal cell that is part of some cortical collecting duct. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney cortex collecting duct intercalated cell Any renal intercalated cell that is part of some cortical collecting duct. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney outer medulla collecting duct principal cell Principal cell that is part of some outer medullary collecting duct. It is known in some mammalian species that this cell may express the epithelial sodium channel (ENaC). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney outer medulla collecting duct intercalated cell Intercalated cell that is part of some outer medullary collecting duct. It is known in some mammalian species that this cell may contribute in the maintenance of acid/base homeostasis. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney inner medulla collecting duct principal cell Any renal principal cell that is part of some inner medullary collecting duct. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney inner medulla collecting duct intercalated cell Any renal intercalated cell that is part of some inner medullary collecting duct. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney papillary duct intercalated cell Any renal intercalated cell that is part of some papillary duct. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney papillary duct principal cell Any renal principal cell that is part of some papillary duct. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
glomerular mesangial cell A mesangial cell located among the glomerular capillaries in a renal corpuscle. Synonyms: intraglomerular mesangial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
glomerular cell Any kidney corpuscule cell that is part of some renal glomerulus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney connecting tubule epithelial cell Any nephron tubule epithelial cell that is part of some renal connecting tubule. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney inner medulla interstitial cell A cell that is part of an interstitial compartment of an inner renal medulla. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney outer medulla interstitial cell A kidney cell that is part of an interstitial compartment of an outer renal medulla. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney proximal convoluted tubule epithelial cell Any epithelial cell of proximal tubule that is part of some proximal convoluted tubule and has part some brush border. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney proximal straight tubule epithelial cell Any epithelial cell of proximal tubule that is part of some proximal straight tubule. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney distal convoluted tubule epithelial cell Any epithelial cell of distal tubule that is part of some distal convoluted tubule. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
macula densa epithelial cell An epithelial cell that is part of the macula densa, characterized by a tightly packed arrangement, apically positioned nuclei, and prominent primary cilia, creating a distinctive 'dense spot' appearance under microscopy. It is involved in regulating renal blood flow, glomerular filtration rate, and renin release. Synonyms: macula densa cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney blood vessel cell A blood vessel cell that is part of a kidney. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney arterial blood vessel cell Any kidney blood vessel cell that is part of some kidney arterial blood vessel. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney capillary endothelial cell An endothelial cell that is part of the capillary of the kidney. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney venous blood vessel cell Any kidney blood vessel cell that is part of some renal vein. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney loop of Henle epithelial cell Any nephron tubule epithelial cell that is part of some loop of Henle. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ureter smooth muscle cell Any smooth muscle cell that is part of some muscular coat of ureter. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
glomerular capillary endothelial cell An endothelial cell that is part of the glomerular capillary of the kidney. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney afferent arteriole cell An endothelial cell which is part of the afferent arteriole in the kidney. This cell is responsible for maintaining renal blood flow and glomerular filtration rate. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney efferent arteriole cell Any kidney arterial blood vessel cell that is part of some renal efferent arteriole. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney loop of Henle ascending limb epithelial cell Any kidney loop of Henle epithelial cell that is part of some ascending limb of loop of Henle. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney loop of Henle descending limb epithelial cell Any kidney loop of Henle epithelial cell that is part of some descending limb of loop of Henle. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
peritubular capillary endothelial cell An endothelial cell that is part of the peritubular capillary of the kidney. This cell is highly fenestrated and plays a vital role in the kidney's filtration process, enabling the exchange of materials between the blood and the renal tubules. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
vasa recta cell A cell that is part of a vasa recta. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney cortex artery cell Any kidney arterial blood vessel cell that is part of some renal cortex artery. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney cortex vein cell Any kidney venous blood vessel cell that is part of some renal cortex vein. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney artery smooth muscle cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney arteriole smooth muscle cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney venous system smooth muscle cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney afferent arteriole endothelial cell An endothelial cell that lines the interior surface of the afferent arteriole and maintains vascular tone. This cell responds to changing ion concentrations and blood pressure by releasing vasoactive substances, in order to regulate blood flow into the glomeruli, which is essential for glomerular filtration. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney afferent arteriole smooth muscle cell A smooth muscle cell found in the wall of the afferent arteriole. This cell contracts and relaxes in response to changes in blood pressure, a process known as a myogenic response, to alter artery diameter and regulate blood flow into the glomeruli. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney efferent arteriole endothelial cell Any endothelial cell that is part of some renal efferent arteriole. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney efferent arteriole smooth muscle cell Any smooth muscle cell that is part of some renal efferent arteriole. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney loop of Henle thick ascending limb epithelial cell An epithelial cell that is part of some loop of Henle thick ascending limb. It is known in some mammalian species that this cell may express the Na+-K+-2Cl− cotransporter (NKCC2) apically. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney loop of Henle thin ascending limb epithelial cell An epithelial cell that is part of some loop of Henle thin ascending limb. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney loop of Henle medullary thick ascending limb epithelial cell An epithelial cell that is part of some loop of Henle thick ascending limb segment located in the renal medulla. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney loop of Henle cortical thick ascending limb epithelial cell An epithelial cell that is part of some loop of Henle thick ascending limb segment located in the renal cortex. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney loop of Henle thin descending limb epithelial cell An epithelial cell that is part of some loop of Henle thin descending limb. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney outer medulla peritubular capillary cell An endothelial cell that is part of the peritubular capillary of the outer renal medulla. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney cortex peritubular capillary cell An endothelial cell that is part of the peritubular capillary of the renal cortex. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
inner renal medulla vasa recta cell Any vasa recta cell that is part of some inner renal medulla vasa recta. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
outer renal medulla vasa recta cell Any vasa recta cell that is part of some outer renal medulla vasa recta. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
vasa recta ascending limb cell A cell that is part of some vasa recta ascending limb. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
arcuate artery cell Any kidney cortex artery cell that is part of some kidney arcuate artery. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
interlobular artery cell Any kidney cortex artery cell that is part of some interlobular artery. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
arcuate vein cell Any kidney cortex vein cell that is part of some kidney arcuate vein. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
interlobular vein cell Any kidney cortex vein cell that is part of some renal interlobular vein. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
inner medulla vasa recta ascending limb cell Any vasa recta ascending limb cell that is part of some inner medulla ascending vasa recta. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
outer medulla vasa recta ascending limb cell Any vasa recta ascending limb cell that is part of some outer medulla ascending vasa recta. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
arcuate artery endothelial cell Any endothelial cell that is part of some kidney arcuate artery. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
arcuate artery smooth muscle cell Any smooth muscle cell that is part of some kidney arcuate artery. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
interlobulary artery endothelial cell Any endothelial cell that is part of some interlobular artery. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
interlobulary artery smooth muscle cell Any smooth muscle cell that is part of some interlobular artery. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
arcuate vein endothelial cell Any endothelial cell that is part of some kidney arcuate vein. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
arcuate vein smooth muscle cell Any smooth muscle cell that is part of some kidney arcuate vein. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
interlobulary vein endothelial cell Any endothelial cell that is part of some renal interlobular vein. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
interlobulary vein smooth muscle cell Any smooth muscle cell that is part of some renal interlobular vein. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney collecting duct cell A cell that is part of a collecting duct of renal tubule. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
vasa recta descending limb cell A cell that is part of some vasa recta descending limb. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
inner medulla vasa recta descending limb cell Any vasa recta descending limb cell that is part of some inner medulla descending vasa recta. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
outer medulla vasa recta descending limb cell Any vasa recta descending limb cell that is part of some outer medulla descending vasa recta. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
renal interstitial pericyte A pericyte cell located in the kidney interstitium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
bladder cell Any cell that is part of some urinary bladder. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
urethra cell Any cell that is part of some urethra. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
bladder urothelial cell A urothelial cell that is part of the urothelium of the urinary bladder. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
urethra urothelial cell A urothelial cell that is part of the urethra urothelium. This cell plays a crucial role in maintaining the urethral barrier function, protecting against toxic substances in urine, sensing environmental changes, and defending against pathogen entry. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney collecting duct principal cell Any renal principal cell that is part of some collecting duct of renal tubule. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney collecting duct intercalated cell Any renal intercalated cell that is part of some collecting duct of renal tubule. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of exocrine pancreas An epithelial cell of the exocrine pancreas. Synonyms: exocrine pancreas cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
periglomerular cell The small neuron in the glomerular layer of the olfactory bulb whose dendrites arborize within a glomerulus, where it receives synaptic input from olfactory receptor cell axon terminals, and also engages in dendrodendritic interactions with mitral and tufted cell dendrites; uses both GABA and dopamine as a neurotransmitter. Synonyms: glomerular layer cell, olfactory bulb (accessory) glomerular layer cell, olfactory bulb glomerular layer cell, olfactory bulb glomerularal cell, olfactory bulb periglomerular cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mitral cell The large glutaminergic nerve cells whose dendrites synapse with axons of the olfactory receptor neurons in the glomerular layer of the olfactory bulb, and whose axons pass centrally in the olfactory tract to the olfactory cortex. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
olfactory bulb tufted cell The principal glutaminergic neuron located in the outer third of the external plexiform layer of the olfactory bulb; a single short primary dendrite traverses the outer external plexiform layer and terminates within an olfactory glomerulus in a tuft of branches, where it receives the input from olfactory receptor neuron axon terminals; axons of the tufted cells transfer information to a number of areas in the brain, including the piriform cortex, entorhinal cortex, olfactory tubercle, and amygdala. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
intestinal enteroendocrine cell The various hormone- or neurotransmitter-secreting cells present throughout the mucosa of the intestinal tract. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stomach enteroendocrine cell The various hormone- or neurotransmitter-secreting cells present throughout the mucosa of the stomach. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lung endothelial cell Any endothelial cell of vascular tree that is part of some lung. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pulmonary artery endothelial cell Any endothelial cell of vascular tree that is part of some pulmonary artery. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
colon endothelial cell A vascular endothelial cell found in colon blood vessels. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
nasopharyngeal epithelial cell Cell of the nasopharyngeal epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
uterine cervix squamous cell Squamous cell of uterine cervix epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
oral mucosa squamous cell Squamous cell of oral epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tonsil squamous cell Squamous cell of tonsil epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
vagina squamous cell Squamous cell of vaginal epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cerebral cortex glial cell Glial cell of cerebral cortex. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lateral ventricle glial cell Glial cell of lateral ventricle. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
appendix glandular cell Glandular cell of appendix epithelium. Example: Goblet cells; enterocytes or absorptive cells; enteroendocrine and M cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mammary gland glandular cell Glandular cell of mammary epithelium. Example: glandular cells of large and intermediate ducts, glandular cells in terminal ducts. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
uterine cervix secretory cell Glandular cell of uterine cervix epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
colon glandular cell Glandular cell of colon epithelium. Example: Goblet cells; enterocytes or absorptive cells; enteroendocrine and M cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
duodenum secretory cell Glandular cell of duodenal epithelium. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Brunner's gland cell. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epididymis secretory cell Glandular cell of epididymal epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
oviduct secretory cell Glandular cell of oviduct epithelium. Example: peg cells, ciliated cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
gallbladder glandular cell Glandular cell of gallbladder epithelium. Synonyms: gall bladder glandular cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
parathyroid glandular cell Glandular (secretory) cell of parathyroid epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
rectum glandular cell Glandular cell of rectal epithelium. Example: Goblet cell; enterocytes or absorptive cells; enteroendocrine and M cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
salivary gland glandular cell Glandular cell of salivary gland. Example: Serous cells, mucous cells, cuboidal epithelial cells of the intercalated ducts, simple cuboidal epithelium of the striated ducts, epithelial cells of excretory ducts. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
seminal vesicle glandular cell Glandular cell of seminal vesicle epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
small intestine secretory cell A glandular cell found in the epithelium of the small intestine. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Somatostatin-secreting Cells (D-cells) . http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pancreas exocrine glandular cell Glandular cell of exocrine pancreas epithelium. Example: pancreatic acinar cell, glandular cells in pancreatic canaliculi, glandular cells in pancreatic ducts. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
adrenal gland glandular cell Hormone secreting cell located in the cortex of adrenal gland. Glandular cells in the adrenal cortex secrete mineralocorticoids, glucocorticoids and androgens. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cerebral cortex endothelial cell A distinct endothelial cell forming the walls of the capillaries within the cerebral cortex. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lung macrophage Circulating macrophages and tissue macrophages (alveolar macrophages) of lung. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
foreskin keratinocyte Keratinocyte from foreskin. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
articular chondrocyte Chondrocyte forming the hyaline cartilage found in joints. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
foreskin fibroblast Fibroblast from foreskin. Synonyms: BJ fibroblast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
muscle fibroblast Fibroblast from muscle organ. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
bone marrow hematopoietic cell Hematopoietic cells resident in the bone marrow. Include: hematopoietic stem cells (lymphoid stem cells and myeloid stem cells) and the precursor cells for thrombocytes, erythrocytes, basophils, neutrophils, eosinophils, monocytes and lymphocytes. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
secretory epithelial cell An epithelial cell that is specialised for the synthesis and secretion of specific biomolecules. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epidermal melanocyte Any melanocyte that is part of a epidermis. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
peripheral blood mononuclear cell A leukocyte with a single non-segmented nucleus in the mature form found in the circulatory pool of blood. Synonyms: PBMC http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
decidual cell A specialized, enlarged, connective tissue cell of the decidua with enlarged nucleus, dense membrane‐bound secretory granules and cytoplasmic accumulation of glycogen and lipid droplets. These cells develop by the transformation of endometrial stromal cells during decidualization. Synonyms: decidua cell, decidual stromal cell, decidualized endometrial stromal cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pituitary gland cell Any cell that is part of a pituitary gland. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
brain macroglial cell Any macroglial cell that is part of a brain. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tonsil germinal center B cell Any germinal center B cell that is part of a tonsil. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
articular chondrocyte of knee joint Chondrocyte forming the hyaline cartilage found in the knee joint. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
microvascular endothelial cell Any blood vessel endothelial cell that is part of a microvascular endothelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
dermis blood vessel endothelial cell Any blood vessel endothelial cell that is part of a dermis. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
dermis lymphatic vessel endothelial cell Any endothelial cell of lymphatic vessel that is part of a dermis. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of pedal digit skin Any skin fibroblast that is part of a pedal digit skin. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of skin of abdomen Any skin fibroblast that is part of a skin of abdomen. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of upper leg skin Any skin fibroblast that is part of a upper leg skin. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of arm Any skin fibroblast that is part of a arm. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lung microvascular endothelial cell Any lung endothelial cell that is part of a microvascular endothelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of peridontal ligament Any fibroblast that is part of a periodontal ligament. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endothelial cell of coronary artery Any endothelial cell of artery that is part of a coronary artery. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
inner cell mass cell Any native cell that is part of a inner cell mass. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
sebaceous gland cell Any native cell that is part of a sebaceous gland. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cardiac septum cell Any native cell that is part of a cardiac septum. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
spinal cord oligodendrocyte Any oligodendrocyte that is part of a spinal cord. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cerebellar basket cell A GABAergic inhibitory interneuron located in the molecular layer of the cerebellar cortex. It projects axons that form specialized synaptic structures around Purkinje cells, including pericellular baskets, which wrap around the Purkinje cell soma, and the pinceau: a brush-like terminal that contacts the initial segment of the Purkinje cell axon. The basket cell modulates Purkinje cell activity through both chemical (GABAergic) and non-synaptic (ephaptic) mechanisms. It is arranged in sagittal rows that align with Purkinje cell zones, contributing to the cerebellum's modular and topographically organized architecture. It plays an essential role in regulating motor coordination and potentially cognitive functions. Synonyms: cerebellum basket cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hypothalamus cell Any native cell that is part of a hypothalamus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
limb basal cell of epidermis Any basal cell of epidermis that is part of a limb. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
bladder microvascular endothelial cell Any microvascular endothelial cell that is part of a urinary bladder. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
dermis microvascular lymphatic vessel endothelial cell Any dermis lymphatic vessel endothelial cell that is part of a microvascular endothelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
embryonic fibroblast Any fibroblast that is part of a embryo. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
brain pericyte Any pericyte cell that is part of a brain. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
brain microvascular endothelial cell Any microvascular endothelial cell that is part of a brain. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
foreskin melanocyte Any melanocyte of skin that is part of a skin of prepuce of penis. Synonyms: melanocyte of foreskin http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ventricular cardiac muscle cell Any cardiac muscle cell that is part of a cardiac ventricle. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
primary motor cortex pyramidal cell Any pyramidal cell that is part of a primary motor cortex. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
splenic fibroblast Any fibroblast that is part of a spleen. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
umbilical artery endothelial cell Any endothelial cell of artery that is part of a umbilical cord. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
splenic endothelial cell Any endothelial cell that is part of a spleen. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hepatic pit cell A large, granular, liver specific natural killer cell that adheres to the endothelial cells of the hepatic sinusoid. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
liver dendritic cell Any dendritic cell that is part of a liver. Synonyms: hepatic dendritic cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Meynert cell Any pyramidal cell that is part of a regional part of cerebral cortex. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
femoral osteoblast Any osteoblast that is part of a femur. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
calvarial osteoblast Any osteoblast that is part of a skull. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
prostate gland microvascular endothelial cell Any microvascular endothelial cell that is part of a prostate gland. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
placental amniotic mesenchymal stromal cell Any mesenchymal stem cell that is part of a placenta. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
placental villus capillary endothelial cell Any capillary endothelial cell that is part of a placenta. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ovarian fibroblast Any fibroblast that is part of a female gonad. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ovarian surface epithelial cell A meso-epithelial cell of the ovarian surface epithelium, varying in shape from flat to cuboidal to pseudostratified columnar. This cell plays a crucial role in ovulation by producing proteolytic enzymes in response to gonadotropins, facilitating follicle rupture through tissue breakdown and TNF-alpha signaling. Additionally, this cell contributes to post-ovulatory wound repair (Morris et al., 2022) and exhibits stem cell-like properties (Flesken-Nikitin et al., 2013; Wang et al., 2019). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ovarian microvascular endothelial cell Any microvascular endothelial cell that is part of a female urethra. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cardiac ventricle fibroblast Any fibroblast that is part of a cardiac ventricle. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cardiac atrium fibroblast Any fibroblast that is part of a cardiac atrium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pericardium fibroblast Any fibroblast that is part of a pericardium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
gallbladder fibroblast Any fibroblast that is part of a gallbladder. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
optic choroid fibroblast Any fibroblast that is part of a optic choroid. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mammary microvascular endothelial cell Any microvascular endothelial cell that is part of a breast. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
adipose microvascular endothelial cell Any microvascular endothelial cell that is part of a adipose tissue. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
migratory cardiac neural crest cell Any migratory neural crest cell that is part of a cardiac neural crest. Synonyms: cardiac neural crest cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
splenocyte Any leukocyte that is part of a spleen. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
anterior visceral endoderm cell Any endodermal cell that is part of a anterior visceral endoderm. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hindlimb stylopod vein endothelial cell Any vein endothelial cell that is part of a hindlimb stylopod. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
skeletal muscle tissue of pectoralis major striated muscle cell Any striated muscle cell that is part of a skeletal muscle tissue of pectoralis major. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
placental pericyte Any pericyte cell that is part of a placenta. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesenchymal stem cell of femoral bone marrow Any mesenchymal stem cell of the bone marrow that is part of a femur. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesenchymal stem cell of abdominal adipose tissue Any mesenchymal stem cell of adipose tissue that is part of an abdomen. Synonyms: mesenchymal stem cell of abdominal adipose http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
melanocyte of skin of face Any melanocyte of skin that is part of a skin of face. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hair follicle dermal papilla cell of scalp Any hair follicle dermal papilla cell that is part of a scalp. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
conjunctiva goblet cell A goblet cell that is part of the conjunctival epithelium, characterized by apical accumulation of mucin granules (containing MUC5AC in humans; Muc5ac/Muc5b in mice). These gel-forming mucins support tear film stability, ocular lubrication, and pathogen defence. The conjunctival goblet cell forms tight junctions with neighbouring epithelial cells via species-specific claudins (claudin-10 in humans, claudin-2 in mice) and regulates immune homeostasis by facilitating soluble antigen transport to dendritic cells through goblet cell-associated antigen passages (GAPs) (Barbosa et al., 2017). The transcription factor SPDEF is essential for its differentiation. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mononuclear cell of umbilical cord Any mononuclear cell that is part of a umbilical cord. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
neocortex basket cell Any basket cell that is part of a neocortex. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
dentate gyrus of hippocampal formation basket cell Any basket cell that is part of a dentate gyrus of hippocampal formation. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Ammon's horn basket cell Any basket cell that is part of a Ammon's horn. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
dentate gyrus granule cell A granule cell that has soma location in the dentate gyrus cell layer of the hippocampal formation and has an elliptical cell body and characteristic cone-shaped tree of spiny apical dendrites. The branches extend throughout the molecular layer and the distal tips of the dendritic tree end just at the hippocampal fissure or at the ventricular surface. The dentate gyrus granule cell is the principal cell type of the dentate gyrus. Synonyms: dentate gyrus of hippocampal formation granule cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
dentate gyrus of hippocampal formation stellate cell Any stellate cell that is part of a dentate gyrus of hippocampal formation. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endometrial microvascular endothelial cell Any microvascular endothelial cell that is part of a endometrial blood vessel. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hair follicular keratinocyte Any keratinocyte that is part of a hair follicle. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
bronchus fibroblast of lung Any fibroblast of lung that is part of a bronchus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
nasal cavity respiratory epithelium epithelial cell of viscerocranial mucosa Any epithelial cell of viscerocranial mucosa that is part of a nasal cavity respiratory epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cord blood hematopoietic stem cell Any hematopoietic stem cell that is part of a umbilical cord blood. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of the reticular layer of dermis A fibroblast of dermis that resides in the deep reticular layer, characterised by robust extracellular matrix production with high type I collagen deposition forming densely packed, organised fibrillar networks (Ghetti et al., 2018). This cell exhibits pro-fibrotic properties during wound healing, entering wounds early where it proliferates and deposits collagen to restore dermal architecture (Knoedler et al., 2023; McAndrews et al., 2022). It is distinguished from papillary dermal fibroblasts by expression of COL11A1, POSTN, and SPP1 in humans (Wu et al., 2022). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ciliated epithelial cell of esophagus A ciliated epithelial cell of the esophagus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Hofbauer cell A tissue-resident macrophage that is part of the placenta. A Hofbauer cell expresses high levels of growth factors and metalloproteinases that support vasculogenesis, angiogenesis, branching morphogenesis and tissue remodeling. A Hofbauer cell has a fetal origin, is found in the villous stroma, chorion, and amnion, and is present throughout pregnancy. Synonyms: fetal Hofbauer cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of breast A fibroblast that is part of the breast. Synonyms: breast fibroblast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibroblast of skin of scalp A fibroblast that is part of the skin of scalp. Synonyms: skin of scalp fibroblast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
nuclear chain fiber A type of intrafusal muscle fiber that has nuclei arranged in a linear row. Unlike nuclear bag fibers, the equatorial region of these fibers (in the centre of the spindle) is not expanded. These fibers are responsible for the detection of changes in muscle length. They are innervated by static gamma motor neurons and are principally associated with type II sensory fibers. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
nuclear bag fiber A type of intrafusal muscle fiber that lies in the center of a muscle spindle. Nuclei are clustered centrally and give the equatorial region a swollen appearance. They are associated with associated with dynamic gamma motor neurons, and the stretching of the equatorial region of the nuclear bag fibers results in an increase in the firing rate of type Ia sensory fibers. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
dynamic nuclear bag fiber A nuclear bag fiber that is sensitive mainly to the rate of change in muscle length. Synonyms: bag1 fiber, nuclear bag1 intrafusal fiber http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
static nuclear bag fiber A nuclear bag fiber that is sensitive only changes in muscle length but not the rate of that change. Synonyms: bag2 fiber, nuclear bag2 intrafusal fiber http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ON retinal ganglion cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
OFF retinal ganglion cell A retinal ganglion cell that is depolarized by decreased illumination of their receptive field center. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
vascular leptomeningeal cell A transcriptomically distinct type of mesothelial fibroblast that is derived from the neural crest, is localized on blood vessels, and is a key component of the pia and arachnoid membranes surrounding the brain. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: Non-neuronal cells', Author Categories: 'CrossArea_subclass', clusters VLMC. Synonyms: VLMC http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesothelial fibroblast A mesothelial cell that has undergone mesothelial-to-mesenchymal transition (MMT) to become a fibroblast cell. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesothelial fibroblast of the leptomeninx A mesothelial fibroblast found in the leptomeninx. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
committed oligodendrocyte precursor An oligodendrocyte precursor cell that is committed to differentiate. Synonyms: COP, differentiation-committed oligodendrocyte precursor http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
meis2 expressing cortical GABAergic cell A GABAergic cell located in the cerebral cortex that expresses meis2. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
brain vascular cell A cell that is part of the brain vasculature. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
large basket cell A basket cell that is large, and typically ascends to give rise to many long horizontally and vertically projecting axon collaterals that traverse neighboring columns and can extend through all cortical layers. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
nest basket cell A basket cell which has simpler dendritic arbors (compared to small or large basket cells), and an axonal plexus of intermediate density, composed of a few long, smooth axonal branches. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
small basket cell A basket cell with axonal arbors composed of frequent, short, curvy axonal branches that tend to be near their somata and within the same layer. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
arachnoid barrier cell A mesothelial fibroblast of the arachnoid barrier layer. Arachnoid barrier cells make up the tight-junctioned layer in the leptomeninx that functions as the physiologic barrier between the cerebrospinal fluid in the subarachnoid space and the fenestrated capillaries in the dura. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
oxytocin-secreting magnocellular cell A magnocellular neurosecretory cell that is capable of producing and secreting oxytocin. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
vasopressin-secreting magnocellular cell A magnocellular neurosecretory cell that is capable of producing and secreting vasopressin. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
displaced amacrine cell A subpopulation of amacrine cell that migrate further than other amacrine cells, and come to lie basal to the inner plexiform layer (IPL) in the ganglion cell layer. Displaced amacrine cells still have their neurites extending apically into the IPL, and therefore exhibit an inverted polarity with respect to the other amacrine cells. Synonyms: dACs, inverted amacrine cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cochlea auditory hair cell An auditory hair cell found in the cochlea. Synonyms: cochlear hair cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
retinoblast A retinal cell that is immature or undifferentiated. Synonyms: retinal stem cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myelinating glial cell A glial cell that myelinates axonal processes. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
octopus cell of the mammalian cochlear nucleus A neuron in the posterior ventral cochlear nucleus that is distinguished by their long, thick and tentacle-shaped dendrites that typically emanate from one side of the cell body. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
double bouquet cell An interneuron that has double bouquet morphology. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cartwheel cell A neuron of the dorsal cochlear nucleus with spiny dendrites that receive input from the axons of granule cells and with axons that release GABA and glycine onto cartwheel, pyramidal and giant cell targets. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
bushy cell A neuron found in the anterior part of the ventral cochlear nucleus that has the appearance of bushes, having short dendrites. Bushy cells give outputs to different parts of the superior olivary complex. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
spherical bushy cell A bushy cell that receives only few large excitatory endbulb synapses from auditory nerves. Spherical bush cells give excitatory input to the lateral and medial parts of the superior olive. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
globular bushy cell A bushy cell that receives a large number of medium-sized synapses, called modified endbulbs. Globular bushy cells extend to the superior olive on both sides of the brainstem where they give input to the bipolar neurons. Synonyms: GBC http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hypendymal cell A neurecto-epithelial cell that is part of the basal layer of the subcommissural organ and specializes in the secretion of proteins into the subarachnoid space. Hypendymal cells have similar characteristics to ependymal cells and express SCO-spondin. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
koniocellular cell A neuron with a small cell body that is located in a koniocellular layer of the lateral geniculate nucleus (LGN). Synonyms: K cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
midget ganglion cell of retina A retinal ganglion cell that originate in the ganglion cell layer of the retina, and project to the parvocellular layers of the lateral geniculate nucleus (LGN). These cells are known as midget retinal ganglion cells due to the small sizes of their dendritic trees and cell bodies. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
parasol ganglion cell of retina A retinal ganglion cell located in the ganglion cell layer of the retina. This cell projects to magnocellular cells in the lateral geniculate nucleus (LGN). They have large cell bodies and extensive, branching dendritic networks that contribute to their large receptive fields. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pulmonary capillary endothelial cell Any capillary endothelial cell that is part of a lung. Synonyms: lung capillary endothelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
alveolar capillary type 1 endothelial cell An alveolar capillary endothelial cell that is located distally to alveolar capillary type 2 endothelial cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
alveolar capillary type 2 endothelial cell An alveolar capillary endothelial cell that is located proximally to alveolar capillary type 1 endothelial cells and in close apposition to alveolar type 1 epithelial cells (also known as type I pneumocytes). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
alveolar type 1 fibroblast cell A pulmonary interstitial fibroblast that is part of the alveolus and contains lipid droplets. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
alveolar adventitial fibroblast A pulmonary interstitial fibroblast that is part of the alveolus and localizes to vascular adventitia. Synonyms: alveolar type 2 fibroblast cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
gamete-nursing cell A cell that supports the development of a gamete by providing it cytoplasmic material (including entire organelles) by direct cross-membrane channels (del Pino, 2021). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
germline-derived nurse cell A gamete-nursing cell that derives from a germline cell (del Pino, 2021). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
somatic nurse-like cell A gamete-nursing cell that derives from the somatic tissues of the gonad (del Pino, 2021). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
choroidal melanocyte A melanocyte located in the vascular uvea and involved in photoprotection, regulation of oxidative damage and immune responses. Synonyms: uveal melanocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stromal cell of thymus A stromal cell that is part of the thymus. Synonyms: thymic stromal cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
effector memory CD45RA-positive, alpha-beta T cell, terminally differentiated An alpha-beta memory T cell with the phenotype CD45RA-positive. Synonyms: TEMRA cell, terminally differentiated effector memory CD45RA+ T cells, terminally differentiated effector memory cells re-expressing CD45RA http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
interstitial cell of thymus A cell that makes up the loose connective tissue of the thymus. Synonyms: thymic interstitial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
thymic nurse cell A large epithelial cell found in the thymus. This cell type may internalize thymocytes through extensions of plasma membrane. The cell surface and cytoplasmic vacuoles of a thymic nurse cell express MHC Class I and MHC Class II antigens. The interaction of these antigens with a developing thymocyte determines whether the thymocyte undergoes positive or negative selection. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney collecting duct beta-intercalated cell A renal beta-intercalated cell that is part of the cortical collecting duct. The medullary collecting duct does not contain the renal beta-intercalated cell type. Synonyms: B-IC, kidney collecting duct intercalated cell type B http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fallopian tube secretory epithelial cell An epithelial cell that is part of the fallopian tube that secretes mucus and oviduct-specific products in response to hormonal stimulation from estrogen and luteinizing hormone. This fallopian tube secretory cell is similar in height to the ciliated cell, but typically exhibits a more narrow, columnar shape. Its nucleus is ovoid and oriented perpendicular to the cell's long axis, with denser chromatin and a smaller nucleolus compared to the ciliated cell. Synonyms: uterine tube secretory epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fallopian tube multiciliated epithelial cell A multi-ciliated epithelial cell that is part of the fallopian tube, mainly found on the apex of the mucosal folds. This cell exhibits a columnar shape with an oval nucleus and is characterized by the presence of cilia on its surface. The coordinated beating of these cilia, together with peristaltic contractions, contributes to the self-propulsion of spermatozoa, the transport of ovum during ovulation and the transport of the fertilized ovum to the intramural fallopian tube. Synonyms: fallopian tube ciliated cell, fallopian tube multiciliated cell, uterine tube ciliated epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pronephric podocyte A specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells in the pronephros. Synonyms: pronephric glomerular visceral epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of proximal tubule segment 1 A brush border cell that is part of segment 1 (S1) of the proximal tubule epithelium, located in the renal cortex. Synonyms: epithelial cell of segment 1 of proximal tubule http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of proximal tubule segment 2 A brush border cell that is part of segment 2 (S2) of the proximal tubule epithelium, located in the renal cortex. In addition to its reabsorptive functions, it is also specialized in the secretion of organic anions and cations, including para-aminohippurate. Synonyms: epithelial cell of segment 2 of proximal tubule http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of proximal tubule segment 3 A brush border cell that is part of segment 3 (S3) of the proximal tubule epithelium, which extends from the medullary rays of the renal cortex into the outer medulla. Synonyms: epithelial cell of segment 3 of proximal tubule http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney loop of Henle short descending thin limb epithelial cell Epithelial cell of the descending thin limb of the short loop (cortical) nephron limited to the outer medulla (mainly inner strip). It is known in some mammalian species that the short descending limb of the loop of Henle selectively expresses the serine protease Corin, the homeobox TF Uncx, and the urea channel Slc14a2. Synonyms: epithelial cell of the descending thin limb of the short loop of Henle http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney loop of Henle long descending thin limb outer medulla epithelial cell Epithelial cell of the descending thin limb of the long loop (juxtamedullary) nephron that spans the outer medulla (inner stripe). It is known in some mammalian species that the long descending limb of the loop of Henle in the outer medulla selectively expresses the secreted activin-antagonist protein follistatin (Fst), the GPI-linked adhesion protein Cdh13, and the protein kinase Stk32a. Synonyms: epithelial cell of the outer medulla of the long descending limb of the loop of Henle http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney loop of Henle long descending thin limb inner medulla epithelial cell Epithelial cell of the descending thin limb of the long loop (juxtamedullary) nephron that spans the inner medulla. It is known in some mammalian species that the long descending limb of the loop of Henle in the inner medulla selectively expresses the nuclear receptor Nr2e3, the Ig kappa chain Igkc, and the secreted protein dermokine (Dmkn). SLC14A2, which expresses a urea transporter, is also expressed in the inner medulla. Synonyms: epithelial cell of the inner medulla of the long descending limb of the loop of Henle http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney collecting duct alpha-intercalated cell A renal alpha-intercalated cell that is part of the collecting duct of the renal tubule. Synonyms: kidney collecting duct intercalated cell type A http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of early distal convoluted tubule An epithelial cell located in the early distal convoluted tubule. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epithelial cell of late distal convoluted tubule An epithelial cell located in the late distal convoluted tubule. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney connecting tubule principal cell A renal principal cell located in the connecting tubule. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney connecting tubule intercalated cell A renal intercalated cell that is part of the renal connecting tubule. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney connecting tubule alpha-intercalated cell A renal alpha-intercalated cell that is part of the renal connecting tubule. Synonyms: connecting tubule A-IC, kidney connecting tubule intercalated cell type A http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
kidney connecting tubule beta-intercalated cell A renal beta-intercalated cell that is part of the renal connecting tubule. Synonyms: connecting tubule B-IC, kidney connecting tubule intercalated cell type B http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
renal medullary fibroblast A fibroblast that is located in the renal medulla interstitium. Synonyms: kidney medullary fibroblast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
respiratory tract hillock cell A hillock cell that is located in respiratory epithelium. In some mammalian species, this cell type has been noted to express KRT13 and KRT4 and is postulated to play a role in squamous barrier function and immunomodulation. Synonyms: hillock cell of respiratory tract, respiratory hillock cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hillock cell An epithelial, transitional cell type between basal and secretory; located in stratified, non-ciliated structures (called hillocks) with high cell turnover in epithelium. In some mammalian species, this cell type has been noted to express KRT13 and is postulated to play a role in squamous barrier function and immunomodulation. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
renal cortical fibroblast A fibroblast that is located in the renal cortical interstitium. Synonyms: kidney cortical fibroblast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
BEST4+ enterocyte An enterocyte of the human intestine expressing bestrophin-4 (BEST4) calcium-activated ion channels. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
GABAergic amacrine cell An amacrine cell that uses GABA as a neurotransmitter. Synonyms: amacrine cell, GABAergic http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
glycinergic amacrine cell An amacrine cell that uses glycine as a neurotransmitter. Synonyms: amacrine cell, glycinergic http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
blood lymphocyte A lymphocyte located in blood. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
peripheral blood lymphocyte A blood lymphocyte located in the flowing, circulating blood of the body. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
interstitial cell Any cell that is located within the interstitium between the cells most prominent in defining a given tissue. "Interstitial cell" is a morphological term and refers to a variety of cells with differing origins and phenotypes. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
valve interstitial cell An interstitial cell that is part of a cardiac valve leaflet. Along with valve endothelial cells, a valve interstitial cell maintains tissue homeostasis for the function of cardiac valves through secreting biochemical signals, matrix proteins and matrix remodeling enzymes. Synonyms: VIC, cardiac valve interstitial cell, valvular interstitial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
valve endothelial cell An endothelial cell that lines a surface of a cardiac valve leaflet. Along with valve interstitial cells, a valve endothelial cell maintains tissue homeostasis for the function of cardiac valves through secreting biochemical signals, matrix proteins and matrix remodeling enzymes. Synonyms: VEC, valvular endothelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
respiratory tract multiciliated cell A multiciliated epithelial cell located in the respiratory tract epithelium, characterized by a columnar shape and motile cilia on its apical surface. This cell develops through a highly orchestrated process, transitioning from a basal progenitor via an intermediate deuterosomal cell stage that generates centrioles essential for ciliogenesis. Synonyms: ciliated cell of the respiratory tract, respiratory ciliated cell, respiratory multiciliated cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
dental pulp stem cell A dental pulp cell that possesses stem-cell-like qualities, including self-renewal capability and multi-lineage differentiation. Synonyms: DPSC http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
early spermatid A spermatid in an early stage of maturation that has a round morphology and is transcriptionally active. Synonyms: round spermatid http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
late spermatid A spermatid in a late stage of maturation that has an elongated morphology and is transcriptionally inert when the acrosome is fully developed. Synonyms: elongated spermatid http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD24-positive, CD-133-positive, vimentin-positive proximal tubular cell A CD24-positive, CD-133-positive, vimentin-positive cell found scattered throughout a renal proximal tubule and that may participate in tubular regeneration. Compared to other proximal tubular cell types, this cell contains less cytoplasm, fewer mitochondria and no brush border. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endometrial multiciliated epithelial cell A multi-ciliated cell of the endometrial epithelium. This cell is characterized by the presence of 9+2 motile cilia on its apical surface, which facilitates the movement of mucus across the endometrial surface. Synonyms: ciliated cell of the endometrium, endometrial ciliated epithelial cell, endometrium ciliated epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
luminal endometrial multiciliated epithelial cell A ciliated cell of the endometrial luminal epithelium. This cell is characterized by the presence of motile cilia on its apical surface. Synonyms: luminal endometrial ciliated epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
glandular endometrial multiciliated epithelial cell A ciliated cell of the endometrial glandular epithelium. This cell is characterized by the presence of motile cilia on its apical surface. Synonyms: glandular endometrial ciliated epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Islands of Calleja granule cell A GABAergic neuron that resides in the islands of calleja and shows the cytoarchitectural and molecular features characteristic of this granule-like cell population. In mice and primates, it expresses D1 and D3 dopamine receptors (Drd1; Drd3), GABAergic markers (GAD1/2) and form densely packed granule cell clusters in the olfactory tubercle within the ventral striatum. Moreover it receives dense dopaminergic input from the VTA, and functionally associated with self-grooming behaviors and depression-like behaviors. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
intermediate cell of urothelium A urothelial cell that is part of the regenerative layer(s) of cells directly superficial to basal cells in urothelium. The layer of intermediate cells in the urothelium ranges from one to several layers thick depending on the species with intermediate cells attached to adjacent cell layers and one another via desmosomes. Synonyms: urothelial intermediate cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
umbrella cell of urothelium A urothelial cell that is terminally differentiated and part of the urothelial apical surface that forms the high-resistance barrier of urothelium. Umbrella cells have been described as the largest of urothelial cell types, highly polarized, and, in some species, multinucleated. In the relaxed state, these cells form a dome-shaped structure at the apical pole and can also cover multiple underlying intermediate cells, leading to the name umbrella cells. In contrast, these cells flatten when the bladder is filled. Synonyms: facet cell of urothelium, superficial cell of urothelium http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
TCR-positive macrophage A macrophage that expresses the T cell receptor complex at the cell surface. Synonyms: T cell receptor positive macrophage, TCR+ macrophage http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ureteric bud cell An epithelial cell that is part of a ureteric bud. A ureteric bud cell has the potential to induce metanephric mesenchymal cells to proliferate and convert to epithelia that form renal tubules via: (1) the secretion of multiple diffusible growth factors that rescue renal progenitors from apoptosis and stimulate them to proliferate and (2) contact-dependent mechanisms that induce mesenchymal-epithelial conversion. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
club-like cell of the urethral epithelium An epithelial cell of the urethra that has an expression profile similar to lung club cells. Club-like cells of the urethra epithelium are similar to lung club cells in their expression of SCGB1A1 and in their enrichment of immunomodulatory programs. Synonyms: club cell of the urethra epithelium, club-like cell of the prostatic urethra epithelium, prostate club cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endothelial cell of venule of lymph node A(n) endothelial cell that is part of a(n) venule of lymph node. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endothelial cell of arteriole of lymph node A(n) endothelial cell that is part of a(n) arteriole of lymph node. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myoepithelial cell of bronchus submucosal gland A(n) myoepithelial cell that is part of a(n) bronchus submucosal gland. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle cell of taenia coli A(n) smooth muscle cell that is part of a(n) taenia coli. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
serous secreting cell of bronchus submucosal gland A(n) serous secreting cell that is part of a(n) bronchus submucosal gland. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endothelial cell of efferent lymphatic vessel A(n) endothelial cell that is part of a(n) efferent lymphatic vessel. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
brush cell of epithelium of lobar bronchus A(n) brush cell that is part of a(n) epithelium of lobar bronchus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
vein endothelial cell of respiratory system A(n) vein endothelial cell that is part of a(n) respiratory system. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
goblet cell of epithelium of lobar bronchus A(n) goblet cell that is part of a(n) epithelium of lobar bronchus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle cell of large intestine smooth muscle circular layer A(n) smooth muscle cell that is part of a(n) large intestine smooth muscle circular layer. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle cell of large intestine smooth muscle longitudinal layer A(n) smooth muscle cell that is part of a(n) large intestine smooth muscle longitudinal layer. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
suprabasal keratinocyte A keratinocyte that resides in the epidermal suprabasal layer and expresses differentiation markers, including keratin 1 and keratin 10, in both humans and mice. In human interfollicular epidermis, this cell retains proliferative capacity and possesses retrodifferentiation potential, acquiring basal-like properties during wound healing or basement membrane contact. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
peg cell A small, narrow, peg-shaped epithelial cell with little cytoplasm that is part of oviduct epithelium. This cell is rarer than the ciliated and secretory epithelial cells of the fallopian tube epithelium and is often found intercalated between them. Peg cells are generally distributed basally along the epithelium and have been found in high concentrations at the fimbriated, distal end of the fallopian tube in humans. It may have a regenerative/stem-cell function. In humans, markers include EPCAM, CD44, and ITGA6. Synonyms: FTE stem-like cell, FTESC, fallopian tube epithelial stem-like cell, intercalary cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
retinal astrocyte A star-shaped glial cell that is part of some retina. This cell links neurons to blood vessels and may provide structural and physiological support to optic nerve head axons. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
secondary crest myofibroblast A myofibroblast that is part of an alveoli during alveolarization. The contractile force of this cell elongates the secondary crest, while producing a framework of elastin and tenascin. During the maturation of the septa, secondary crest myofibroblasts, together with matrix fibroblasts, secrete metalloproteinases and other ECM‐remodeling proteins to thin the septal tip ECM. The secondary crest myofibroblast continues producing elastin, eventually undergoing apoptosis during adulthood. Synonyms: secondary-crest myofibroblast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
bronchiolar smooth muscle cell A smooth muscle cell that is part of a bronchiole. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lung megakaryocyte A megakaryocyte that is resident in the lung connective tissue. Synonyms: lung resident megakaryocyte, lung-resident megakaryocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ON-blue cone bipolar cell An ON bipolar cell type with dendrites selectively contacting S-cones. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mucus secreting cell of trachea gland A mucus secreting cell that is part of a submucosal gland of the trachea. Synonyms: tracheal submucosal gland mucous cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myoepithelial cell of trachea gland A myoepithelial cell that is part of a submucosal gland of the trachea. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mucus secreting cell of bronchus submucosal gland A mucus secreting cell of a submucosal gland of the bronchus. Synonyms: bronchial gland mucous cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
airway submucosal gland collecting duct epithelial cell An epithelial cell that is part of a collecting duct of an airway submucosal gland. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
airway submucosal gland duct basal cell A basal cell that is part of a duct of an airway submucosal gland. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
perichondrial fibroblast A fibroblast that is part of the fibrous layer of the perichondrium. This cell is responsible for collagen fiber production. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lung perichondrial fibroblast A perichondrial fibroblast that is part of the lung. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
diffuse bipolar 1 cell An OFF diffuse bipolar cell that makes synaptic contact with both L/M and S-cone photoreceptors and only minimal contact with rod photoreceptors. Synonyms: Diffuse Bipolar Cell Type DB1 http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
diffuse bipolar 2 cell An OFF diffuse bipolar cell that predominantly connects to ON parasol cells and lateral amacrine cells. This cell contains a large number of synaptic ribbons and a small axon arbor area. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
diffuse bipolar 3a cell An OFF calbindin-positive bipolar cell that has a large dendritic field and stratifies narrowly close to the middle of the inner plexiform layer. Its axon terminal is characterized by regularly branching and varicose processes resembling beads on a string. Most of DB3a contacts with cones are triad-associated. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
diffuse bipolar 3b cell An OFF calbindin-negative bipolar cell that has a large dendritic field and stratifies narrowly close to the middle of the inner plexiform layer. Its axon terminal is characterized by regularly branching and varicose processes resembling beads on a string. Most of DB3b contacts with cones are non-triad-associated. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
diffuse bipolar 4 cell An ON diffuse bipolar cell that predominantly connects to ON parasol cells and lateral amacrine cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
diffuse bipolar 6 cell An ON diffuse bipolar cell that has a large dendritic field and large axon terminals, which show little or no overlap. This cell predominantly connects to narrow thorny ganglion cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
flat midget bipolar cell An OFF bipolar cell with a small dendritic tree that provides most of the triad-associated basal (flat) contacts at cone pedicles. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
invaginating midget bipolar cell An ON bipolar cell with a small dendritic tree that forms most of the central (invaginating) elements opposite the synaptic ribbon at the cone triad. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
giant bipolar cell An ON bipolar cell that has large dendritic and axonal fields. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
OFFx cell An OFF bipolar cell that is fovea-specific and expresses FEZF1, NXPH1 and NXPH2. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mucus secreting cell of tracheobronchial tree submucosal gland A mucus secreting cell of a submucosal gland of the tracheobronchial tree. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lung resident memory CD4-positive, alpha-beta T cell An alpha-beta CD4 T cell that resides in the lung. Synonyms: lung resident memory CD4 T cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lung resident memory CD8-positive, alpha-beta T cell An alpha-beta CD8 T cell that resides in the lung. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lung resident memory CD8-positive, CD103-positive, alpha-beta T cell A lung resident memory CD8-positive, alpha-beta T cell that is CD103-positive. Synonyms: lung TRM CD8-positive, CD103-positive cell, lung TRM CD8-positive, integrin alpha E-positive cell, lung resident memory CD8-positive CD103-positive, alpha-beta T cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CCL3-positive alveolar macrophage An alveolar macrophage that expresses CCL3. Synonyms: alveolar macrophage CCL3-positive http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
metallothionein-positive alveolar macrophage An alveolar macrophage that expresses metallothionein. Synonyms: alveolar macrophage MT-positive, alveolar macrophage metallothionein-positive http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lung interstitial macrophage A macrophage that is part of the lung connective tissue (pulmonary interstitium). This cell performs tissue remodeling and contributes to barrier immunity through antigen presentation. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
deuterosomal cell An epithelial cell part of respiratory tract epithelium that is a precursor of a multi-ciliated cell. This cell actively amplifies centrioles, a required step for multiciliogenesis. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lung migratory dendritic cell A dendritic cell that captures antigens in a lung and migrates to a lymph node or to the spleen to activate T cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ON midget ganglion cell A midget ganglion cell that depolarizes in response to increased light intensity in the center of its receptive field. The majority of input that this cell receives comes from invaginating midget bipolar cells. Synonyms: ON-midget RGC, ON-midget cell, inner stratifying midget cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
OFF midget ganglion cell A midget ganglion cell that depolarizes in response to decreased light intensity in the center of its receptive field. The majority of input that this cell receives comes from flat midget bipolar cells. Synonyms: OFF-midget RGC, OFF-midget cell, outer stratifying midget cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
respiratory tract suprabasal cell A respiratory epithelial cell derived from a basal cell, with a topographic nuclear position between the basal and luminal cells of the airway epithelium. This non-basal, intermediate progenitor cell has limited proliferative capacity and can differentiate into multiciliated, secretory, or rare airway cells (ionocytes, tuft cells, neuroendocrine cells). It shares some ultrastructural features with basal cells but lacks the defined characteristics of fully differentiated cellular phenotypes. Synonyms: respiratory parabasal cell, respiratory suprabasal cell, respiratory suprabasal progenitor cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
taste receptor cell of tongue A taste receptor cell that is part of a taste bud of a tongue. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
OFF parasol ganglion cell A parasol ganglion cell that depolarizes in response to decreased light intensity in the center of its receptive field. The majority of input that this cell receives comes from DB3a bipolar cells. Synonyms: OFF-parasol RGC, OFF-parasol retinal ganglion cell, outer parasol cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
ON parasol ganglion cell A parasol ganglion cell that depolarizes in response to increased light intensity in the center of its receptive field. The majority of input that this cell receives comes from DB4 bipolar cells. Synonyms: ON-parasol RGC, ON-parasol retinal ganglion cell, inner parasol cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
small bistratified retinal ganglion cell A bistratfied retinal ganglion cell with a small dendritic field that has dendrites in the ON and OFF sublamina of the retinal inner plexiform layer and carries blue-ON/yellow-OFF signals. This cell receives bipolar and amacrine input to both the OFF and ON dendritic tree. Synonyms: small bistratified cell, small bistratified cell, blue-ON/yellow-OFF ganglion cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
perivascular cell A cell that is adjacent to a vessel. A perivascular cell plays a crucial role in maintaining vascular function and tissue homeostasis. This cell type regulates vessel integrity and flow dynamics. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
airway submucosal gland duct multiciliated cell A multi-ciliated epithelial cell located in ciliated duct of an airway submucosal gland, characterized by a columnar shape and motile cilia on its apical surface. Synonyms: airway submucosal gland duct ciliated cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
onychocyte A terminally differentiated, specialized keratinocyte originating primarily from the nail matrix. During onychokeratinization, these cells undergo progressive flattening and produce high levels of hard, disulfide cross-linked keratins (Eckhart et al., 2024) that form the rigid, compact nail plate. Unlike epidermal keratinocytes, onychocytes are firmly integrated into the nail plate and do not desquamate. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
luminal adaptive secretory precursor cell of mammary gland A luminal epithelial cell of the mammary gland that can proliferate and has the potential to differentiate into a lactocyte during pregnancy. In humans, a luminal adaptive secretory precursor cell can be identified by high levels of the markers EpCAM and CD49f, and in mice it can be identified by low levels of CD29 and high levels of CD14, Kit, CD61, and Tspan8. Synonyms: ER-negative luminal alveolar progenitor http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
luminal hormone-sensing cell of mammary gland A luminal epithelial cell of the mammary gland that transduces endocrine cues to orchestrate proliferation, architectural remodeling, and differentiation of other cells in the mammary gland via paracrine signaling. This cell expresses high levels of estrogen receptors. In humans, a luminal hormone-sensing cell can be identified by high levels of EpCAM and low levels of CD49f, and in mice it can be identified by low levels of CD29 and high levels of Foxa1, CD133, and Sca1 (Ly6a). Synonyms: ER-positive luminal hormone-sensor cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lactocyte type 1 A lactocyte that highly expresses genes associated with transcription, immune cell function, and cellular stress. A lactocyte type 1 also expresses genes involved in milk component biosynthesis (e.g., LALBA and CSNs), albeit at lower levels than a lactocyte type 2. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lactocyte type 2 A lactocyte that highly expresses genes associated with lipid production and milk component biosynthesis. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endothelial cell of central vein of liver An endothelial cell that is part of a central vein of liver. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
interstitial extravillous trophoblast cell A trophoblast cell that invades the uterine wall to anchor the placenta to the uterus. An interstitial extravillous trophoblast cell differentiates from an extravillous trophoblast cell, becoming hyperchromatic and changing its morphology to a fibroblast-like spindle-shaped cell. In humans, this cell can be distinguished by the expression of placental-specific protein 8, which stimulates migration. Synonyms: invasive interstitial extravillous trophoblast cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endovascular extravillous trophoblast cell A trophoblast cell that invades the maternal spiral arteries and replace the endothelial lining, remodeling the vessels and allowing for adequate blood transport into the placenta. An endovascular extravillous trophoblast cell differentiates from an extravillous trophoblast cell. In humans, this cell can be distinguished by the expression of CD56. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
uterine resident macrophage A tissue-resident macrophage that is part of the uterus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
preplasmablast A mature B cell that serves as an intermediate stage in the differentiation of naive B cells into a plasmablast. A preplasmablast expresses CD30 and IL-6R and lacks expression of CD20, CD23, CD38 and CD138. Synonyms: pre-plasmablast, preplasmablastic cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pre-granulosa cell A supporting cell that is part of the ovary and differentiates into a granulosa cell. A pre-granulosa cell develops from an early supporting gonadal cell by repressing testis determination, which can then proliferate to form primordial follicles. Synonyms: ovarian pregranulosa cell, pregranulosa cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mural granulosa cell A follicular cell of ovary that differentiates from a cuboidal granulosa cell during the secondary follicle stage. Mural granulosa cells line the inner surface of the follicle wall, surrounding the fluid-filled antral cavity. These cells produce oestrogen during the follicular phase in response to follicle-stimulating hormone (FSH), and progesterone after ovulation in response to luteinizing hormone (LH). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cycling B cell A(n) B cell that is cycling. Synonyms: proliferating B cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cycling T cell A(n) T cell that is cycling. Synonyms: proliferating T cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cycling dendritic cell A(n) dendritic cell that is cycling. Synonyms: proliferating dendritic cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cycling natural killer cell A(n) natural killer cell that is cycling. Synonyms: proliferating natural killer cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cycling gamma-delta T cell A(n) gamma-delta T cell that is cycling. Synonyms: proliferating gamma-delta T cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cycling monocyte A(n) monocyte that is cycling. Synonyms: proliferating monocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cycling CD8-positive, alpha-beta T cell A(n) CD8-positive, alpha-beta T cell that is cycling. Synonyms: proliferating CD8-positive, alpha-beta T cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cycling CD4-positive, alpha-beta T cell A(n) CD4-positive, alpha-beta T cell that is cycling. Synonyms: proliferating CD4-positive, alpha-beta T cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cycling macrophage A(n) macrophage that is cycling. Synonyms: proliferating macrophage http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cycling alveolar macrophage A(n) alveolar macrophage that is cycling. Synonyms: proliferating alveolar macrophage http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cycling mononuclear phagocyte A(n) mononuclear phagocyte that is cycling. Synonyms: proliferating mononuclear phagocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cycling endothelial cell of lymphatic vessel A(n) endothelial cell of lymphatic vessel that is cycling. Synonyms: proliferating endothelial cell of lymphatic vessel http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cycling pulmonary alveolar type 2 cell A(n) pulmonary alveolar type 2 cell that is cycling. Synonyms: proliferating pulmonary alveolar type 2 cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cycling myeloid cell A(n) myeloid cell that is cycling. Synonyms: proliferating myeloid cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cycling basal cell A(n) basal cell that is cycling. Synonyms: proliferating basal cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
squamous granulosa cell A granulosa cell that has a squamous morphology and form a single layer around the oocyte in primordial follicles. This cell develops directly into a cuboidal granulosa cell during the primordial-to-primary follicle transition. Synonyms: flattened granulosa cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cuboidal granulosa cell A granulosa cell that has a cuboidal morphology and develops from squamous granulosa cell during the transition between primordial follicle to primary follicle. Cuboidal granulosa cells proliferate to form a second layer within secondary follicles. Synonyms: columnar granulosa cell, cuboidal epithelial granulosa cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
diffuse bipolar 5 cell An ON diffuse bipolar cell that stratifies in the stratum 3 of the inner plexiform layer to make synapses with ON parasol ganglion cells. A diffuse bipolar 5 cell has high expression of MYO16 compared with other bipolar cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lipid-associated macrophage A tissue-resident macrophage that is associated with lipids. This cell responsible of anti-inflammatory functions, lipid accumulation and enhancing phagocytosis (Wculek et al., 2022, Liu et al., 2022). In mice and humans, a lipid-associated macrophage is characterized by the marker Trem2 (Jaitlin et al., 2019). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
placental resident macrophage A tissue-resident macrophage that is part of the placenta. This cell helps preventing immunological rejection of the fetus by modulating the immune environment. A placental resident macrophage has high plasticity to adapt to the changing needs of each phase of pregnancy. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
decidual resident macrophage A resident macrophage that is part of the decidua. Some decidual macrophages are derived from maternal blood monocytes that are recruited to the uterus shortly after conception. The main functions of a decidual macrophage are implantation, placental development, immune regulation and vascular remodeling. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
atretic follicular cell of ovary A follicular cell of ovary that has begun to degenerate and undergo atresia, a specialized apoptosis. This cell is found in an atretic follicle, which is an ovarian follicle that started to mature but failed to reach full development and instead regresses. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
atretic granulosa cell A granulosa cell that is undergoing atresia. This cell type displays distinct morphological alterations compared with a healthy granulosa cell, including pyknosis (nuclear condensation) and cellular shrinkage. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
CD57-positive enterocyte An enterocyte that is part of a duodenal epithelium and expresses beta-1,3-glucuronyltransferase 1 (B3GAT1), also known as CD57 or HNK-1. Synonyms: CD57+ enterocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
limbal epithelial stem cell of cornea A stem cell that is part of the corneo-scleral limbus. This cell type resides at the basal layer of the epithelium and has a small size and high nuclear to cytoplasmatic ratio (Secker and Daniels, 2009). A limbal stem cell is responsible for corneal epithelial renewal and repair (Li et al., 2023), and to help maintain a clear corneal surface by preventing conjunctival epithelial cells from migrating onto the cornea (Wang et al., 2023). Synonyms: limbal epithelial stem cell, limbal stem cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
age-associated B cell A transcriptionally distinct memory B cell whose presence increases with age, during infections, and in autoimmune diseases. In humans and mice, this cell type can be identified by the expression of T-bet, CD11c, CD11b, and the lack of CD21. An age-associated B cell responds to TLR stimuli, may produce autoantibodies, and participates in antiviral responses and pathogen clearance. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
diffuse bipolar 4a cell An ON bipolar cell that has high expression of DIRC3, KCNJ3, LINC01915, PTPRK compared with other bipolar cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
diffuse bipolar 4b cell An ON bipolar cell that has high expression of NOS1AP compared with other bipolar cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Schlemm's canal endothelial cell A specialised endothelial cell that is part of the canal of Schlemm. This cell type shares characteristics and expresses markers of both blood and lymphatic endothelial cells (Kizhatil et al., 2014) and regulates aqueous humor outflow resistance by modulating pore formation and responding to mechanical strain (Stamer et al., 2015). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
inner wall Schlemm's canal endothelial cell A Schlemm's canal endothelial cell that lines the inner wall of the Schlemm's canal. This cell exhibits a cobblestone appearance due to the significant biomechanical load it experiences, as well as the segmental flow of aqueous humor. The degree of biomechanical stress can lead to the formation of dome-like outpouchings known as giant vacuoles. In addition, the cell contains transcellular pores that mediate aqueous humor transport (Dautriche et al., 2015). This endothelial cell also displays prominent peripheral F-actin bands which help maintain structural integrity under pressure (Ethier et al., 2004). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
outer wall Schlemm's canal endothelial cell A Schlemm's canal endothelial cell that lines the outer wall of the Schlemm's canal. This cell displays a smooth and flat morphology (Dautriche et al., 2015) and it is distinguished by the presence of Weibel-Palade bodies, specialized organelles that produce, store, and release P-Selectin (Hamanaka et al., 1992). This endothelial cell also exhibits stellate (star-shaped) actin arrangements distributed throughout much of the cell (Ethier et al., 2004). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
glial restricted tripotential precursor cell A glial precursor cell that generates oligodendrocytes and type-1 and type-2 astrocytes. It has been shown in some mammals that this cell type may express A2B5, nestin, FGFR-1, FGFR-2, FGFR-3, PLP, and DM-20 antigens. Unlike oligodendrocyte precursor cell, it does not initially express PDGFR-alpha and can differentiate into both type-1 and type-2 astrocytes. Synonyms: tripotential glial-restricted precursor cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
chorionic girdle cell A horse-specific, highly invasive trophoblast cell that invades the endometrium where it forms endometrial cups. Synonyms: equine chorionic girdle cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
enteroglial cell Glial cell that provides support to the enteric nervous system. It is involved in enteric neurotransmission, in maintaining the integrity of the mucosal barrier of the gut and serves as a link between the nervous and immune systems of the gut. In enteric nerve strands, glial processes ensheath multiaxonal bundles which distinguishes enteric glia from all other peripheral glia. Ultrastructurally, the most conspicuous trait of an enteroglial cell is the presence of 10 nm filaments, which criss-cross the cell body, form axial bundles in the processes and appear to firmly anchor the cells to the ganglionic surfaces. Similar to astrocytes, their main constituent is glial fibrillary acidic protein (GFAP). Synonyms: enteric glial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fetal pre-type II pulmonary alveolar epithelial cell Precursor of type II pneumocyte. These cells do not have lamellar bodies, which are a marker of type II pneumocyte maturity. Synonyms: fetal alveolar pre-type II epithelial cell, fetal pre-type 2 pneumocyte, fetal pre-type II alveolar epithelial cell, fetal pre-type II pneumocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesenchymal stem cell of orbital adipose tissue Any mesenchymal stem cell of adipose tissue that is part of an orbital region. Synonyms: OAMSC, Orbital ASCs, orbital adipose-derived mesenchymal stem cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mesenchymal stem cell of apical papilla A mesenchymal stem cell that is part of the apical papilla tooth root. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
dermal chromatophore A chromatophore that is part of the dermis. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
border associated macrophage A central nervous system macrophage that is part of a choroid plexus, a meninx and a perivascular space. A border associated macrophage interacts with various components of the CNS vasculature and meninges, it participates in immune surveillance and in the regulation of the blood brain barrier. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
choroid epiplexus macrophage A choroid plexus macrophage that is part of the apical surface of some choroid plexus epithelium. This macrophage has a star-like shaped body. Synonyms: Kolmer’s cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stromal choroid plexus macrophage A choroid plexus macrophage that is part of a choroid plexus stroma. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
dural macrophage A border associated macrophage which is part of a dura matter. This macrophage phagocytoses intruding pathogens and foreign molecules detected in the bloodstream or in the cerebrospinal fluid. This cell has an amoeboid body with dynamic protrusions in homeostasis. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
protoplasmic astrocyte An astrocyte with highly branched protrusions, found in neocortex layers 2-6. It is involved with the formation and elimination of synapses, glutamate clearance, modulation of synaptic functions and regulation of blood flow in response to synaptic activity. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibrous astrocyte A cell type located in the first layer of the neocortex with radial protrusions extending transversely into the deeper cortex layers, herby facilitating communication across neurons, astrocytes, capillaries, meninges and cerebrospinal fluid through contact with neurons, pia mater and capillaries. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
interlaminar astrocyte An astrocyte type that presents radial protrusions across the layers of a cortex. The soma of this astrocyte is part of the first layer of a neocortex. This astrocyte extents its protrusions transversally to the deeper layers of a cortex and it creates contact with neurons, the pia matter and capillaries. This astrocyte is involved in facilitating the communication across neurons, astrocytes, capillaries, meninges and the cerebrospinal fluid. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pial interlaminar astrocyte An interlaminar astrocyte whose soma is part of the first layer of a neocortex and is in contact with a pia surface. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
subpial interlaminar astrocyte An interlaminar astrocyte type whose soma is part of the upper first layer of the neocortex and its processes extend to a pia surface. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
nasal serous secreting cell A serous secreting cell that is part of a submucosal gland in the nasal cavity respiratory epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
alpha1-tanycyte The dorsal-most tanycyte type of the third venticle. These cells projects into the ventromedial or dorsomedial nucleus of the hypothalamus. This type of tanycyte extends its protrusions close to parenchymal neurons without contacting blood vessels. It expresses the glial marker S-100β. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
alpha2-tanycyte Tanycyte of the third ventricle, located immediately ventral to alpha-1 tanycytes. These cells project to the ventromedial and arcuate nuclei of the hypothalamus and express the glial marker S-100β. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
beta1-tanycyte A type of tanycyte located in ventral part of the lateral wall of the third ventricle and in the lateral infundibular recess of the brain. This tanycyte has an elongated morphology with multiple microvilli extending into the median eminence. This type of tanycyte expresses FGF receptors 1 and 2, is in contact with GnRH neurons, and is involved in the release of gonadotropin-releasing hormone (GnRH). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
beta2-tanycyte A type of tanycyte located in the floor of third ventricle and the infindibular recess. This tanycyte has an elongated morphology with multiple microvilli extending medially and ventrally to the median eminence, contacting the pial surface and blood vessels. This type of tanycyte expresses FGF receptors 1 and 2, is in contact with GnRH neurons, and is involved in the release of gonadotropin-releasing hormone (GnRH). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
astrocyte-restricted precursor A progenitor cell of the central nervous system that differentiates exclusively onto astrocytes. This progenitor cell expresses CD44 and S100 calcium-binding protein B. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immune oligodendroglia An oligodendrocyte of the central nervous system that exhibits immune properties such as self-presentation and non-self antigen presentation to T cells, phagocytosis of debris, and cytokine and chemokine production. Immune oligodendroglia is immunoreactive during inflammation, neurodegenerative disorders, chronic stress and major depressive disorder. Synonyms: immune oligodendrocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cycling stromal cell A(n) stromal cell that is cycling. Synonyms: proliferating stromal cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cycling glial cell A(n) glial cell that is cycling. Synonyms: proliferating glial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cycling plasma cell A(n) plasma cell that is cycling. Synonyms: proliferating plasma cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
cycling type EC enteroendocrine cell A(n) type EC enteroendocrine cell that is cycling. Synonyms: proliferating type EC enteroendocrine cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fetal artery endothelial cell An endothelial cell that lines an artery in the fetal circulatory system. Synonyms: endothelial cell of fetal artery, fetal arterial EC, fetal artery EC http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
immature pericyte A pericyte that is in an early stage of development, found in newly forming or remodeling blood vessels. An immature pericyte is characterized by it's mesenchymal stem cell-like properties and high proliferative capacity, which allows it to differentiate into various types of pericytes and contribute to the structural and functional maturation of the vasculature. Immature pericytes are stellate in new vessels and elongated with less protrusions in remodeling vessels. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fetal vein endothelial cell An endothelial cell that lines the veins in the fetal circulatory system. Synonyms: fetal venous endothelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
angiogenic pericyte A specialized pericyte that actively participates in the formation of new blood vessels during angiogenesis by undergoing phenotypic changes, increasing proliferation, and interacting closely with endothelial cells. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
transit amplifying cell of gut A transit amplifying cell of the gut epithelium, located in the wall of the intestinal crypt, just above intestinal stem cells from which they derive. These are rapidly dividing cells, capable of multiple rounds of division before differentiating into the various cell types of the gut epithelium (enterocyte, goblet, eneterodendocrine, paneth cells). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
early colonocyte An enterocyte that is part of the colon, in the early stages of differentiation, located in the intestinal crypt-villus axis. Synonyms: early enterocyte of colon http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
early enterocyte An enterocyte in the early stages of development, located above the transit-amplifying cell zone in the intestinal crypt-villus axis. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
intestinal lamina propria fibroblast A fibroblast located in the lamina propria of the intestinal mucosa. This cell expresses PDGFRα and CD81 and is negative for α-smooth muscle actin (α-SMA). This cell is predominantly located in the small intestine adjacent to myofibroblasts surrounding the crypts. It is capable of synthesizing extracellular matrix components and structural proteins such as collagen and elastin. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type G cell of stomach Any type G enteroendocrine cell that is part of some epithelium of stomach. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
post-arteriole capillary cell An endothelial cell forming the walls of capillaries immediately downstream from arterioles, facilitating the exchange of substances between blood and interstitial fluid. This cell is characterized by a small diameter and may be continuous, fenestrated, or sinusoidal, depending on their location and function. This cell plays a crucial role in tissue oxygenation, nutrient delivery, and maintaining homeostasis within the microvascular network. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pre-venule capillary cell A specialized endothelial cell located in the transition zone between capillaries and small venules in the microvascular system. It exhibits characteristics of both capillary and venous cells, expressing markers from both types. This cell plays a role in regulating blood flow and substance exchange between blood and tissues. Synonyms: Cap-Venous endothelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
secretory pericyte A specialized pericyte located within the basement membrane of a blood capillary. This cell is characterized by its ability to produce and release a variety of bioactive molecules, collectively known as the pericyte secretome, including cytokines and regulators of angiogenesis. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle cell of stomach A smooth muscle cell that is part of the muscularis externa of the stomach wall. It is characterized by its fusiform shape, involuntary control, and ability to generate slow, sustained contractions. This cell is organized in distinct layers and is essential for gastric motility and digestion. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stomach smooth muscle outer longitudinal layer cell A specialized smooth muscle cell located in the outermost layer of the muscularis externa of the stomach wall. This cell is arranged longitudinally along the stomach's axis and is responsible for the contractions that facilitate food movement toward the pylorus. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stomach smooth muscle circular layer cell A smooth muscle cell located in the middle layer of the muscularis externa of the stomach wall. This cell is arranged concentrically with the stomach's longitudinal axis, forming a continuous sheet of contractile tissue. It is fusiform in shape, containing actin and myosin filaments that enable contraction without striations. This cell contributes to the mechanical digestion and movement of food within the stomach through coordinated contractions, and plays a role in forming the pyloric sphincter in the pyloric region. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
stomach smooth muscle inner oblique layer cell A smooth muscle cell found in the innermost layer of the muscularis externa of the stomach wall. This cell forms a unique layer of smooth muscle fibers oriented obliquely to the stomach's longitudinal axis. It is responsible for aiding in the mixing and churning of gastric contents, contributing to mechanical digestion within the stomach. Synonyms: stomach smooth muscle oblique layer cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
smooth muscle circular layer cell A smooth muscle cell that is found in the inner muscular layer of hollow organs. It is characterized by its spiral/helical arrangement around organ lumens. This cell is crucial for peristaltic movements in organs. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type 1 myenteric plexus glia An enteric glial cell located within the myenteric ganglia of the gastrointestinal tract. This cell has a small somata and has very short, irregularly branched processes that surround neuron cell bodies, giving it a protoplasmic-like appearance. It plays crucial roles in modulating myenteric neuron activity, regulating oxidative stress, and influencing neuroinflammation and neurogenesis. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type 1 submucosal plexus glia An enteric glial cell that is associated with neuron cell bodies within submucosal ganglia of the gastrointestinal tract. This cell is located in the submucosa, a layer of connective tissue beneath the intestinal mucosa. This cell plays a role in modulating secretomotor neuron activity and contributes to the regulation of digestive fluid secretion and absorption. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type 2 interganglionic glia An enteric glial cell that has an elongated, fibrous morphology with long processes that run parallel to nerve fibers connecting enteric myenteric ganglia. This cell is located in the interganglionic fiber tracts of the enteric nervous system. Synonyms: type II enteric glia http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type 3 mucosal glia An enteric glial cell located in the lamina propria of the intestinal mucosa. This cell plays important roles in maintaining gut barrier function, regulating intestinal homeostasis, and mediating interactions between the enteric nervous system and the immune system. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type I enteric glial cell An enteric glial cell located within the ganglia of the enteric nervous system. This cell is characterized by it’s small somata and short, irregularly branched processes that surround neuronal cell bodies in the myenteric and submucosal ganglia. This cell plays important roles in modulating neuronal activity and neurogenesis in the gastrointestinal tract. Synonyms: intraganglionic glia, type 1 enteric glia, type I enteric glia http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type 4 muscularis propria glia An enteric glial cell characterized by a small central soma that extends long, thin, bipolar projections. This cell is primarily located along small nerve fibers within the muscle layers of the gastrointestinal tract and is known for its unbranching processes that closely follow these nerve fibers in the muscularis. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
small intestine BEST4+ enterocyte An enterocyte of the human small intestine expressing bestrophin-4 (BEST4) calcium-activated ion channels. These enterocytes have a disinctive transcriptomic profile and are scattered through the small intestine epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
BEST4+ colonocyte An enterocyte of the human colon expressing bestrophin-4 (BEST4) calcium-activated ion channels. These cells have a distinct transcriptomic profile compared to other enterocytes and are scattered through the colon epithelium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
TREM2-positive macrophage A macrophage characterized by high expression of Triggering Receptor Expressed on Myeloid cells 2 (TREM2), found in various tissues including the liver, adipose tissue, bone, gut (Colonna, 2023), and tumor microenvironments, where it is associated with immunosuppressive and anti-inflammatory activity (Colmenares, 2024; Khantakova, 2022). This cell exhibits a distinct gene expression profile in the tumor microenvironment, including overexpression of complement system genes (C1QA, C1QB, C1QC, C3), and SPP1 in both mice and humans (Xiong, 2020; Khantakova, 2022). It is involved in phagocytosis, tissue repair, and modulation of immune responses (Coeho, 2021). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
migratory dendritic cell A dendritic cell capable of capturing antigens in peripheral tissues and migrating through blood or lymphatic vessels to secondary lymphoid organs, where it presents processed antigens to T cells. It expresses MHC class II molecules and lacks lineage markers associated with other leukocyte populations, distinguishing it as a member of the dendritic cell lineage. This cell plays a pivotal role in initiating and regulating adaptive immune responses by linking peripheral antigen capture with T cell activation in lymphoid tissues. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
large mucus secreting cholangiocyte A columnar, mucin-producing cholangiocyte that lines large bile ducts, including the hilar bile duct, right and left hepatic bile ducts, and large intrahepatic bile ducts. This cell expresses phosphorylated STAT3 and TFF-3 in humans and mice. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
BAG3-positive monocyte A circulating mononuclear phagocyte characterized by the expression of BCL-2-associated athanogene 3 (BAG3) protein, a co-chaperone involved in protein quality control and anti-apoptotic processes. (Fontanella, 2009). It undergoes cellular stress during the differentiation into M2 macrophages and is linked to poor survival rates in multiple cancer types. (Park, 2023) Synonyms: BAG3+ monocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
liver-resident natural killer cell A natural killer cell resident to the liver, located in the hepatic sinusoids. In humans this cell type is distinguished from circulating natural killer cells by CD49a or CD69 gene expression. Liver-resident natural killer cells have also been shown to express CCR5, EOMES, KLRB1, GZMK, and CXCR6 in humans. Synonyms: he-NK, hepatic NK, hepatic natural killer cells, intrahepatic NK, liver NK cell, liver resident natural killer cell, liver-specific natural killer cell, lr-NK http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
multiciliated ependymal cell An ependymal cell that lines the lateral, third, and fourth ventricles of the brain. The cell is characterized by multiple motile cilia on its apical surface, which beats in a coordinated manner to facilitate the movement of cerebrospinal fluid (CSF), contributing to brain homeostasis. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
syncytial cell A multinucleate cell formed by the fusion of multiple uninuclear cells through plasma membrane fusion. This process leads to a single large cell containing multiple nuclei within a shared cytoplasm. Synonyms: syncytium http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
intestinal villus capillary endothelial cell A capillary endothelial cell that is part of the intestinal villus. This cell is highly fenestrated, with fenestrations most numerous at the villus tips, and plays a vital role in nutrient absorption and maintaining the selective permeability of the intestinal barrier. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
intestinal fibroblastic reticular cell A specialized fibroblastic reticular cell that is part of gut-associated lymphoid tissue (GALT), responsible for forming a structural network that facilitates immune cell interactions. This cell is found in Peyer's patches, cryptopatches, and isolated lymphoid follicles. It plays crucial roles in maintaining intestinal immunity by controlling innate lymphoid cell homeostasis and function, organizing lymphoid structures, and contributing to intestinal microbiome balance. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
intestinal subserosal fibroblast A fibroblast that is part of the subserosa of intestine. This cell interacts with immune cells and play roles in inflammation and fibrosis. In certain conditions, such as Crohn's disease, subserosal fibroblast may differentiate into myofibroblasts. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
intestinal enteroendocrine progenitor An epithelial cell that is part of the crypt of Lieberkuhn, originating from intestinal stem cells and giving rise to enteroendocrine cells (EECs). In mouse and human, this cell can be characterized by the expression of Neurog3, and has the ability to proliferate and differentiate into multiple EEC subtypes. Its proliferative potential contributes to crypt growth, distinguishing it from fully differentiated EECs. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
subepithelial intestinal fibroblast A fibroblast located adjacent to the intestinal epithelium in both the small intestine and colon, specifically around the crypts. This cell is characterized by the expression of PDGFRα and various collagen isoforms, including COL4A5 and COL4A6. It secretes signalling molecules like TGF-β, Wnt ligands, and BMPs, which are crucial for epithelial homeostasis, intestinal stem cell support, and basement membrane formation. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
crypt-bottom fibroblast A subepithelial intestinal fibroblast that is located adjacent to the base of the crypt of Lieberkühn, near the intestinal stem cells. Characterized by low PDGFRα expression, this cell is crucial for maintaining the intestinal stem cell niche. Crypt-bottom fibroblast secretes key signaling molecules including canonical Wnt ligands (Wnt2, Wnt2b), Wnt potentiators (Rspo3), and BMP inhibitors (Grem1), which collectively regulate intestinal stem cell function and epithelial homeostasis. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
crypt-top fibroblast A subepithelial intestinal fibroblast that is located adjacent to the top of the crypt of Lieberkuhn. Characterized by high experession of PDGFRα, this cell secretes a range of signaling factors, including WNTs and BMPs, that drive epithelial differentiation, creating a gradient that regulates the balance between stem cell maintenance and differentiation. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pre-theca cell A stromal cell that serves as a precursor to the theca cell layers in the ovary growing follicles. This cell is present in the early stages of follicular growth, particularly in smaller follicles. Unlike mature theca cell, a pre-theca cell is initially non-steroidogenic and lacks luteinizing hormone receptors. Synonyms: early theca cell, progenitor theca cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
follicle associated enterocyte An enterocyte found in the follicle-associated epithelium (FAE) that covers Peyer's patches and other mucosa-associated lymphoid tissues. This cell has reduced absorptive capacity and expresses higher levels of chemokines CCL20 and CXCL16, compared to regular villus enterocytes. It contributes to antigen sampling and immune interactions, supporting the specialized function of the FAE in mucosal immunity. Synonyms: follicle-associated epithelium enterocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
interna theca cell A specialized theca cell that forms the inner, highly vascularized layer of the theca surrounding ovarian follicles. Originating from progenitor theca cells, the theca interna cell is steroidogenic, playing a crucial role in the production of androgens, which serves as a precursor for estrogen synthesis in granulosa cells. This cell expresses luteinizing hormone receptors, enabling it to respond to hormonal signals that regulate steroidogenesis. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
externa theca cell A specialized theca cell that forms the outer layer of the theca surrounding the ovarian follicle, appearing at the antral follicle. Originating from progenitor theca cells, theca externa cell is characterized by its fibroblast-like appearance and primarily function to provide structural support to the developing follicle. This cell produces collagen fibers and extracellular matrix components such as Col1a1 and Col1a2. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pancreatic islet capillary endothelial cell A capillary endothelial cell that is part of islet of Langerhans, characterized by a high density of fenestrations —approximately ten times greater than those in exocrine pancreatic capillaries. These fenestrations facilitate efficient hormone exchange, which is essential for maintaining glucose homeostasis. The cell's structure and function are regulated by the local production of vascular endothelial growth factor-A (VEGF-A), which maintains its fenestrated architecture. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
endocrine gland capillary endothelial cell Any capillary endothelial cell that is part of an endocrine gland. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
pituitary gland capillary endothelial cell A capillary endothelial cell that is part of the pituitary gland. This cell is characterized by its fenestrated structure which facilitates the efficient transport of hormones and other signaling molecules, essential for endocrine signalling. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
choroid plexus capillary endothelial cell A capillary endothelial cell that is part of the choroid plexus, characterized by its fenestrated nature with 60 to 80 nm fenestrations and lack of tight junctions. This fenestrated structure allows for the rapid delivery of water and other components, aiding in the production of cerebrospinal fluid (CSF). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fallopian tube epithelial cell Any epithelial cell that is part of the fallopian tube. Synonyms: uterine tube epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fallopian tube non-ciliated epithelial cell Any epithelial cell that is part of the fallopian tube and lacks cilia. Synonyms: fallopian tube non-ciliated cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
lung resident granzyme K-associated CD8 T cell A granzyme K-associated CD8 T cell that resides in the lung, characterized by the expression of granzyme K (GZMK), and tissue residency markers CD103 and CD49a. This cell exhibits cytotoxic potential through its expression of multiple granzymes (GZMA, GZMB, GZMH, GZMM) in addition to GZMK. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
granzyme K-associated CD8 T cell A CD8 T cell characterized by high expression of Granzyme K (GZMK). This cell is enriched in both inflamed tissues, such as synovial tissue in rheumatoid arthritis and respiratory tissues during COVID-19, as well as non-inflamed tissues like the gut and kidneys. Unlike highly cytotoxic GZMB+ CD8+ T cell, GZMK+ CD8+ T cell exhibits lower direct cytotoxic potential, and is involved in producing pro-inflammatory cytokines such as IFN-γ and TNF-α. Synonyms: granzyme K+ CD8 T cell, tissue-enriched expressing GzmK CD8 cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fallopian tube smooth muscle cell A smooth muscle cell that is part of the fallopian tube. This cell is responsible for peristaltic contractions that facilitate gamete and embryo transport, fluid mixing, and embryo admission to the uterus. Synonyms: uterine tube smooth muscle cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
luminal endometrial unciliated epithelial cell An epithelial cell that is part of the endometrial luminal epithelium, forming a continuous layer lining the uterine cavity. This cell undergoes cyclical changes during the menstrual cycle, proliferating under estrogen in the proliferative phase, and differentiating under progesterone in the secretory phase to prepare for potential implantation. During the window of implantation, this cell changes from a tall columnar shape to a shorter columnar or cuboidal form, loses polarity, and becomes receptive to blastocyst implantation. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
type IIx muscle cell A fast type II muscle cell that is part of the skeletal muscle tissue. This cell is characterized by its intermediate metabolic profile, utilizing both glycolytic and oxidative pathways for energy production. In humans, it is distinguished by the expression of myosin heavy chain 1 (MYH1). Synonyms: type 2x fiber, type 2x muscle cell, type 2x muscle fiber, type IIx muscle fiber http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
atretic theca cell A theca cell undergoing atresia, characterized by distinct morphological changes including hypertrophy, altered cell shape, and disrupted layered organization. This cell exhibits reduced steroidogenic capacity and changes in surrounding vascularization. The onset of theca cell atresia can vary, occurring at different stages of follicle atresia depending on the phase of folliculogenesis. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
uterine natural killer cell A natural killer cell that is part of the uterus, specifically within the endometrium during the non-pregnant state and in the decidua during pregnancy. This cell exhibits dynamic changes in frequency throughout the menstrual cycle, with lower levels during menstruation and a significant increase during the mid-secretory phase and early pregnancy. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
subpleural fibroblast A fibroblast that is located beneath the visceral pleura of the lung. This cell contributes to the development of idiopathic pulmonary fibrosis (IPF) by forming fibrotic lesions that originate subpleurally and extend into lung tissue through activation, proliferation, migration, and differentiation into a myofibroblast. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
adventitial fibroblast A fibroblast of the adventitia of a blood vessel. This cell contributes to vascular homeostasis, remodeling, and inflammation by producing extracellular matrix components, cytokines, and growth factors. Adventitial fibroblast can transition into an activated state during injury or disease, marked by increased proliferation, migration, matrix deposition, and contractile protein expression http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
respiratory airway secretory cell A secretory epithelial cell of the respiratory and terminal bronchioles. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
granzyme H-associated CD8 T cell A CD8 T cell characterized by high expression of Granzyme H (GZMH). This cell exhibits a restricted TCR repertoire and elevated expression of cytotoxic, exhaustion, and type I interferon-stimulated gene signatures compared to controls. Synonyms: granzyme H+ CD8 T cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
biliary tuft cell A tuft cell that is part of the extrahepatic biliary tree, including the gallbladder and extrahepatic bile ducts. It shares a core genetic program with intestinal tuft cells but has unique tissue-specific genes. Biliary tuft cell functions as a bile acid-sensitive regulator, suppressing inflammation and modulating microbiome-dependent neutrophil infiltration in biliary tissues. Unlike its intestinal counterparts, this cell decreases in number postnatally as bile acid production matures, with its abundance negatively regulated by bile acids. Synonyms: gallbladder/extrahepatic bile duct tuft cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tuft cell of thymus A tuft cell that is part of the medullary epithelium of the thymus, characterized by lateral microvilli and specific markers, including L1CAM in both mice (Zhang et al., 2022) and humans (Sun et al., 2023), as well as MHC II in mice (Miller et al., 2018). This cell is pivotal in immune functions such as antigen presentation, central tolerance, and type 2 immunity. A tuft cell in the thymus exhibits characteristics of both a medullary thymic epithelial cell (mTEC) and a peripheral tuft cell. Its development is governed by transcription factors such as POU2F3. Synonyms: thymic tuft cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tuft cell of pancreatic duct A tuft cell that is part of the epithelium of pancreatic duct. Present in humans and rats, this cell is absent in the murine pancreas under normal conditions but emerges during acinar-to-ductal metaplasia triggered by injury, inflammation, or oncogenic mutations. It modulates the immune response and protects against pancreatic ductal adenocarcinoma progression by producing suppressive eicosanoids, such as prostaglandin D2. A tuft cell in the pancreatic duct highly expresses the transcription factor POU2F3, which is essential for its development and presence. Synonyms: pancreatic brush cell, pancreatic tuft cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tuft cell of nasal cavity A tuft cell that is part of the nasal cavity epithelium, located in both the respiratory and olfactory epithelia of the nose. This cell plays key roles in chemosensation, lipid mediator production, immune responses, and epithelial homeostasis. Synonyms: nasal brush cell, nasal tuft cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tuft cell of olfactory epithelium A tuft cell that is part of the olfactory epithelium, characterized by a globular body and the expression of neurogranin (Nrgn) in mice. This cell plays a crucial role in allergen recognition and regulating olfactory stem cell proliferation via TRPM5-dependent ATP sensing and cysteinyl leukotriene production. Unlike nasal respiratory tuft cells, it has low to absent expression of taste receptors, including the G protein Gα gustducin, and rarely contacts olfactory sensory neurons directly. Synonyms: olfactory tuft cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tuft cell of nasal cavity respiratory epithelium A tuft cell that is part of the nasal cavity respiratory epithelium. Acting as a chemosensor, it detects bitter taste ligands and bacterial signals via taste receptors, maintaining epithelial-microbial homeostasis by stimulating antimicrobial peptide secretion from adjacent epithelial cells. This cell is a major source of IL-25, promoting type 2 immune responses and potentially contributing to chronic rhinosinusitis (O'Leary et al., 2019). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tuft cell of submandibular gland A tuft cell that is part of the epithelium of the submandibular gland, localized to the striated ducts in mice, pigs, and humans, and to the main excretory ducts in rats. This cell is characterized by chemosensory functions, potential roles in immune regulation, and possible involvement in salivary secretion via acetylcholine release. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tuft cell of stomach A tuft cell that is part of the epithelium of the stomach. This cell is characterized by gastric chemosensation and immune regulation through IL-25 secretion, which activates ILC2s to produce IL-13, driving epithelial remodelling and tuft cell expansion. Unlike intestinal tuft cells, which are primarily involved in helminth defense and type 2 immunity, the tuft cell of the stomach is primarily involved in inflammation, metaplasia, and hyperplasia. Synonyms: gastric tuft cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tuft cell of auditory tube A tuft cell that is part of the epithelium of the pharyngotympanic (auditory) tube. This chemosensory cell is often positioned near cholinoreceptive sensory nerve fibers, suggesting a role in neuroimmune communication. It detects chemical signals and releases neuropeptides, such as acetylcholine (ACh) and CGRP, which contribute to inflammatory responses that help protect deeper tissues from harmful substances. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tuft cell of urethra A tuft cell that is part of the epithelium of the urethra. This cell monitors urethral contents by detecting chemical stimuli, such as bitter compounds and sugars. Upon activation, it stimulates sensory nerve fibres and triggers detrusor muscle contraction, likely aiding in pathogen clearance by promoting bladder emptying. Synonyms: urethral brush cell, urethral cholinergic chemosensory cell, urethral tuft cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
steroidogenic stromal cell of ovary A stromal cell that is part of the ovarian stroma, characterized by its ability to synthesize steroid hormones. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
early luteal cell A luteal cell that is part of the young, developing corpus luteum. This cell promotes progesterone synthesis, marked by high Parm1 expression in mice (Lan et al., 2024). An early luteal cell is associated with steroidogenesis and cell growth, contributing to early corpus luteum function and maturation. Synonyms: active corpus luteum cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
late luteal cell A luteal cell that is part of the older, regressing corpus luteum. This cell exhibits increased expression of genes involved in progesterone metabolism - Akr1c18 in mice (Lan et al., 2024), cell cycle arrest, and apoptosis. A late luteal cell contributes to corpus luteum regression and eventual clearance from the ovary through luteolysis. Synonyms: regressing corpus luteum cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
intercalated cell of salivary gland A cuboidal epithelial cell that is part of the intercalated duct of salivary gland. This cell expresses proteins commonly associated with acinar cells and displays calcium signaling characteristics similar to secretory cells, indicating an active role in the secretory process rather than ion reabsorption. Synonyms: salivary intercalated duct cells http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
striated cell of salivary gland An columnar/cuboidal epithelial cell that is part of the striated duct of salivary gland, characterized by basal striations formed by infoldings of the plasma membrane. This cell play a crucial role in modifying the electrolyte composition and concentration of saliva through active ion transport, particularly the absorption of sodium and secretion of potassium. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
luminal epithelial cell of endometrium An epithelial cell that is part of an endometrium luminal epithelium. Synonyms: endometrial luminal epithelial cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
uterine natural killer cell 1, human ​​A uterine natural killer subset that is present in the endometrial lining during the non-pregnant state (Garcia-Alonso et al., 2021) and in the decidua during pregnancy (Vento-Tormo et al., 2018). It expresses the uterine resident marker CD49a and is distinguished from uNK2 and uNK3 by CD39 expression and the absence of CD103 (Whettlock et al., 2022) and CD160 (Marečková et al., 2024). It also expresses higher levels of killer-cell immunoglobulin-like receptors (KIRs) and leukocyte immunoglobulin-like receptor B1 (LILRB1), which facilitate interaction with human leukocyte antigens (HLAs) on extravillous trophoblast cells, promoting immune tolerance and implantation. Enriched in the endometrium post-ovulation (Marečková et al., 2024) and prominent in early pregnancy (Whettlock et al., 2022), uNK1 regulates trophoblast invasion and spiral artery remodeling (Zhang & Wei, 2021). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
uterine natural killer cell 2, human A uterine natural killer subset that is present in the endometrial lining during the non-pregnant state (Garcia-Alonso et al., 2021) and in the decidua during pregnancy (Vento-Tormo et al., 2018), peaking in the first trimester. It expresses the uterine resident marker CD49a and is distinguished from uNK1 and uNK3 by the absence of CD39, CD103 (Whettlock et al., 2022), and CD160 (Marečková et al., 2024), with ITGB2 serving as a defining marker (Vento-Tormo et al., 2018). Functionally, it produces more cytokines upon stimulation than uNK1, suggesting a role in immune defense, and secretes XCL1 chemokines, facilitating interactions with maternal dendritic cells and fetal extravillous trophoblasts (Vento-Tormo et al., 2018). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
uterine natural killer cell 3, human A uterine natural killer subset found in the endometrial lining during the non-pregnant state (Garcia-Alonso et al., 2021) and in the decidua during pregnancy (Vento-Tormo et al., 2018), becoming the dominant uNK subset late in pregnancy. It expresses the uterine resident marker CD49a and is distinguished from uNK1 and uNK2 by CD160 (Marečková et al., 2024) and CD103 expression, the absence of CD39, and low KIR levels (Whettlock et al., 2022). Resembling intraepithelial ILC1 cells, uNK3 primarily supports uterine immune defense (Huhn et al., 2020) and indirectly influences trophoblast behavior through chemokine secretion, such as CCL5 (Vento-Tormo et al., 2018). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature NK T cell, human A mature NK T cell that can be identified by the expression of CD56 in humans. Synonyms: mature NK T lymphocyte, human, mature NK T-cell, human, mature NK T-lymphocyte, human, mature NKT cell, human, mature natural killer T cell, human, mature natural killer T lymphocyte, human, mature natural killer T-lymphocyte, human http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Merkel cell of epidermis A Merkel cell found mainly in the basal layer of the epidermis and the outer root sheath of hair follicles, particularly concentrated in areas with high tactile acuity, such as touch domes, hair follicles, and fingertips. Synonyms: epdiermal Merkel cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
spinous cell A differentiating keratinocyte found in the epidermis and oral epithelium, located in the stratum spinosum, characterized by a spiny appearance due to abundant intercellular desmosomal junctions. Synonyms: prickle cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
epidermal keratinocyte A keratinocyte of the skin epidermis that synthesizes keratin and undergoes successive stages of differentiation as it migrates from the basal layer to the cornified (stratum corneum) layer. These differentiation stages include the basal, spinous (prickle), and granular cell layers. This cell is central to epidermal homeostasis, mediating wound healing, immune modulation, including the secretion of cytokines and chemokines that recruit neutrophils (Simmons and Gallo, 2024), and intercellular communication with adjacent melanocytes (Marrapodi and Bellei, 2024). Synonyms: keratincyte of epidermis, skin keratinocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
onychofibroblast A specialized fibroblast located in the onychodermis that play a key role in nail growth and regeneration by interacting with LGR6-positive nail matrix keratinocytes. These interactions mediate essential signaling pathways, particularly WNT signaling, which is critical for epithelial–mesenchymal communication and coordinated nail development. In humans, this cell expresses key markers, including RSPO4, MSX1, WIF1, and BMP5, all involved in nail differentiation. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
nail bed keratinocyte A keratinocyte that resides in the nail bed, responsible for tightly attaching the nail plate to the underlying dermis. Unlike typical epidermal keratinocytes, it exhibits limited proliferation, undergoes modified differentiation that skips the granular layer and conventional cornification, and primarily ensures adhesion and maintenance of the nail plate. In humans, this cell expresses characteristic markers, including the protease inhibitor SPINK6 and the differentiation-associated protein KRT16. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
nail matrix keratinocyte A keratinocyte that is part of the nail matrix epithelium, distinguished by its high proliferative capacity and its role in nail plate formation via onychokeratinization, a differentiation process that uniquely bypasses the formation of a granular layer, resulting in the production of hard, compact keratin. Unlike skin epidermal keratinocytes, this cell expresses a distinctive mix of hard (hair-type) and select epidermal keratins (Kitahara and Ogawa, 1993). In humans, LGR6 and WNT6 are enriched in the basal compartment, with LGR6 marking nail stem cells in both mice and humans, and exhibiting strong expression in the human proximal nail matrix (Kim et al., 2021). Synonyms: nail matrix epithelial keratinocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
serous acinar cell of salivary gland An acinar cell of the salivary gland, characterized by a pyramidal or triangular shape with a spherical nucleus and abundant eosinophilic zymogen granules. This cell secretes watery, enzyme‐rich fluid containing α-amylase, proline-rich proteins, and secretory immunoglobulins for starch digestion and antimicrobial defence. In humans and mice, serous acinar cell predominates in the parotid gland and to a lesser extent in the submandibular gland, where it exists alongside mucous acinar cells (Maruyama et al., 2019). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mucous acinar cell of salivary gland An acinar cell of the salivary gland, responsible for producing a viscous, mucin‐rich solution, thereby facilitating lubrication and protection of the oral mucosa. This cell is characterized by an elongated shape, clear cytoplasm filled with mucin granules, and a basally compressed nucleus (Barrows et al., 2020). In humans and mice, the mucous acinar cell predominates in the sublingual gland and minor salivary glands, while also being present in mixed glands such as the submandibular gland, where it coexists with serous acinar cells (Maruyama et al., 2019). http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
seromucous acinar cell of salivary gland An acinar cell of the salivary gland, with a hybrid seromucous phenotype, co-expressing serous and mucous markers and producing a mixed secretion of enzymes-containing serous fluid and mucins essential for lubrication, digestion, and antimicrobial defense. Predominant in the submandibular glands of humans and mice, its differentiation and secretory gene expression are regulated by FGFR2b–MAPK signaling, driven by paracrine FGF7 from adjacent myoepithelial cells, which provides a key niche signal for seromucous identity. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
excretory duct cell of salivary gland A duct epithelial cell that is part of the excretory duct of the salivary gland, which transports saliva from the intralobular ductal system to the oral cavity. While primarily serving as a conduit, this cell may play a role in the saliva modification, contributing to its hypotonicity. In humans, this cell has a pseudostratified columnar shape. Synonyms: salivary excretory duct cell http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
dual-feature fallopian tube progenitor cell A bipotent progenitor cell within the human fallopian tube epithelium, characterized by the concurrent expression of epithelial (e.g., EpCAM/CD326) and endothelial (e.g., PECAM1/CD31) markers at both the cell surface and transcript levels. This cell has the capacity to differentiate into ciliated and secretory epithelial cells, as well as potentially endothelial/stromal lineages. Positioned at the apex of lineage bifurcation, the cell exhibits stem-like and endothelial features, representing an intermediate developmental state between undifferentiated progenitors and lineage-committed epithelial cells. Synonyms: unclassified fallopian tube progenitor http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
quiescent fibroblast A fibroblast in a quiescent state, characterized by a smaller, spindle-shaped morphology with a relatively small cytoplasm, modest rough endoplasmic reticulum and condensed chromatin. Despite low proliferation and contractility, it maintains high metabolic activity for extracellular-matrix homeostasis through continuous matrix protein turnover and mechanosensitive signaling. This cell can rapidly differentiate into contractile myofibroblasts under injury or inflammatory cues to drive tissue repair. Synonyms: inactive fibroblast http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
IgD-negative class switched memory B cell A class switched memory B cell that lacks IgD on the cell surface. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
newly formed oligodendrocyte A post-mitotic oligodendrocyte that has exited the cell cycle and begun early stage differentiation. The cell begins to acquire oligodendrocyte-like characteristics but has not yet initiated myelination. In mice, NFOL is marked by the expression of Tcf7l2 and Cemip2 (also known as Tmem2), among other early myelin-related genes. These markers highlight cells transitioning from a precursor to a more differentiated, pre-myelinating state. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
myelin-forming oligodendrocyte A postmitotic and differentiated oligodendrocyte derived from a oligodendrocyte progenitor cell. A myelin-forming oligodendrocyte begins the expression of myelin genes and actively engages in the myelination process. In mice and humans, it is characterized by the upregulation of the key myelin-associated markers Mbp and Opalin. Additionally, Ctps (CTP synthase) shows peak expression at this stage, suggesting a heightened demand for nucleotide biosynthesis during membrane expansion and myelin production. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
mature myelinating oligodendrocyte A post-mitotic oligodendrocyte derived from a myelin-forming oligodendrocyte (MFOL). A mature Myelinating Oligodendrocyte is a fully differentiated cell that is actively engaged in myelination. In addition to high expression of canonical myelin genes (e.g., Mbp, Plp1, Mog), a MOL can be distinguished by the expression of stage-enriched genes Grm3, Klk6, Ptgds, Anxa5, and Hopx in mice. These markers reflect the functional specialization of a mature oligodendrocyte, including roles in signalling, lipid metabolism, and myelin maintenance. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
tanycyte of vascular organ of lamina terminalis A specialized, non-ciliated ependymal glial cell located in the ventricular wall of the organum vasculosum of the lamina terminalis (OVLT) and characterized by elongated basal processes extending into the parenchyma to contact fenestrated capillaries. In mice, it is characterised by the expression of tight junction proteins (claudin 1, occludin, ZO-1) forming a continuous honeycomb junctional pattern. This cell contributes to a functional blood–cerebrospinal fluid (CSF) barrier at the ventricular interface of the OVLT. Synonyms: tanycyte-like cell of OVLT, tanycyte-like ependymal cell of OVLT http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
monocyte-derived Kupffer cell A Kupffer cell located within the hepatic sinusoids, derived from circulating bone marrow monocytes that acquire the phenotypic markers and functional properties of resident Kupffer cells through niche-dependent imprinting, typically following depletion of the embryonically derived Kupffer cell population. During liver injury, MoKCs become the dominant Kupffer cell subset, exhibiting enhanced proliferation, resistance to apoptosis, and key roles in tissue repair and fibrosis attenuation. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
hair follicle dermal stem cell A bipotent mesenchymal stem cell that resides in the dermal sheath, specifically within the dermal sheath cup at the base of the hair follicle, characterized by its capacity for self-renewal and differentiation into both dermal sheath and dermal papilla cells throughout hair cycling. In humans, this cell is marked by enriched expression of gremlin-2 (GREM2) and dipeptidase-1 (DPEP1), and acts as a progenitor reservoir sustaining and regenerating the follicle's mesenchymal compartments. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
fibrochondrocyte A chondrocyte with hybrid fibroblastic-chondrogenic characteristics found in fibrocartilage, particularly in the avascular inner zone and transitional middle zone of the meniscus. In humans, fibrochondrocytes are marked by predominant expression of type I collagen (COL1A1) and fibril-associated collagens (COL3A1, COL6A1), while retaining type II collagen (COL2A1) expression and exhibiting lower SOX9 than hyaline chondrocytes. This molecular profile underlies the synthesis of abundant type I collagen essential for fibrocartilage matrix and reflects an intermediate phenotype between fibroblast and chondrocyte. Synonyms: fibrocartilage chondrocyte http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
Islands of Calleja granule cell (Primate) A Islands of Calleja granule cell of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:OT D1 ICj. Synonyms: D1-ICj (Islands of Calleja), OT D1 ICj, OT Granular GABA http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
juxtacanalicular tissue cell A trabecular meshwork cell of the juxtacanalicular tissue (JCT), characterized by a spindle-shaped, fibroblast-like morphology within a loose extracellular matrix immediately adjacent to Schlemm's canal. It expresses CHI3L1 (human and mouse) and ANGPTL7 (human), as well as smooth muscle actin for contractility. Unlike other trabecular meshwork cells, it does not form monolayers but exists in a loose network, regulating aqueous humor outflow resistance through continuous ECM remodelling, mechanotransduction, and formation of intracellular pores historically called giant vacuoles. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
beam A cell A beam cell within the eye's trabecular meshwork, molecularly distinguished by FABP4 expression in humans and spatially intermingled with Beam B cells throughout the uveal and corneoscleral meshwork regions. In mice, a transcriptionally analogous Beam A–like cluster (mC14) exists, sharing core TM markers (Myoc, Mgp, Pdpn, Chil1) and functional attributes. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
suprabasal cell An epithelial cell that resides in the layer(s) immediately above the basal layer in stratified or pseudostratified epithelia. This cell mainly originates from basal cells and is found across various tissues, including skin, esophagus, oral mucosa, airway, and cornea. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
beam cell A trabecular meshwork cell that is part of the eye's trabecular meshwork, residing in the uveal and corneoscleral meshwork regions and serving as the primary biological filter in the aqueous humor drainage cascade. This cell exhibits endothelial-like properties, including production of antithrombogenic substances such as tissue plasminogen activator, while also demonstrating phagocytic activity to remove cellular debris from aqueous humour before the fluid moves deeper into the less porous juxtacanalicular tissue. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl
beam B cell, human A trabecular meshwork cell within the eye's trabecular meshwork. This cell is molecularly distinguished by TMEFF2 expression in humans. A beam B cell is spatially intermingled with beam A cells throughout the uveal and corneoscleral meshwork regions, but demonstrates a tendency to localise closer to the juxtacanalicular tissue. http://purl.obolibrary.org/obo/cl/releases/2026-03-26/cl.owl